Plegiocard Injection: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting during or after the injection
- Slow or irregular heartbeat
- Difficulty breathing or shortness of breath
- Severe muscle weakness or inability to move limbs
- Confusion or extreme drowsiness
- Swelling of face, lips, or throat
- Chest pain or tightness
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is plegiocard injection used for?
This medicine is an injectable combination of magnesium carbonate and potassium chloride used to treat low magnesium and low potassium levels, especially in hospital settings. It is given by a healthcare professional and requires monitoring of blood levels and heart rhythm.
- Generic Name: Magnesium Carbonate (162.65mg) + Potassium Chloride (59.65mg)
- Manufacturer: Samarth Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 plegiocard injection के बारे में (Hindi Summary)
उपयोग: यह दवा मैग्नीशियम कार्बोनेट और पोटैशियम क्लोराइड का इंजेक्शन है। इसका उपयोग शरीर में मैग्नीशियम और पोटैशियम की कमी को पूरा करने के लिए किया जाता है। यह अस्पताल में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है। यह दिल की धड़कन को सामान्य करने, मांसपेशियों की कमजोरी और ऐंठन को कम करने, और कुछ मामलों में गंभीर दमा या प्री-एक्लेम्पसिया में मदद करती है। इसे घर पर स्वयं नहीं लगाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में चेहरे पर गर्मी लगना, पसीना आना, चक्कर आना, जी मिचलाना और इंजेक्शन की जगह पर दर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और धीरे-धीरे इंजेक्शन देने पर कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन धीमी हृदय गति, अनियमित धड़कन, सांस लेने में कठिनाई, गंभीर मांसपेशियों की कमजोरी और एलर्जी प्रतिक्रिया हो सकती है। ऐसा होने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा अस्पताल या क्लिनिक में ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। इंजेक्शन से पहले अपने डॉक्टर को अपनी सभी दवाओं, खासकर पानी की गोलियां, ब्लड प्रेशर और दिल की दवाओं के बारे में बताएं। अगर आपको किडनी या दिल की बीमारी है, या आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर को जरूर बताएं। इंजेक्शन के दौरान चक्कर आना, धड़कन धीमी होना या मांसपेशियों में कमजोरी महसूस हो तो तुरंत बताएं। इंजेक्शन के बाद तब तक वाहन न चलाएं जब तक आप पूरी तरह सतर्क न हो जाएं।
💊 plegiocard injection Uses & Benefits
[{"condition":"Hypomagnesemia with hypokalemia","description":"Used to correct low magnesium and low potassium levels when oral supplements are not enough or not possible.","evidence":"Well-established"},{"condition":"Cardiac arrhythmias due to electrolyte imbalance","description":"Helps stabilize heart rhythm in patients with low magnesium or potassium, especially after heart surgery or in intensive care.","evidence":"Well-established"},{"condition":"Severe asthma exacerbation","description":"Magnesium can help relax bronchial smooth muscle and is sometimes added to standard treatment in severe attacks.","evidence":"Moderate"},{"condition":"Preeclampsia and eclampsia","description":"Magnesium is used to prevent and treat seizures in pregnant women with severe preeclampsia, often with potassium monitoring.","evidence":"Well-established"},{"condition":"Digitalis toxicity","description":"Magnesium and potassium can help manage certain arrhythmias caused by digitalis overdose.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Intravenous magnesium is sometimes used in emergency settings for acute migraine, but evidence for prevention is limited.","evidence":"Limited"},{"condition":"Postoperative pain management","description":"Magnesium infusion may reduce opioid requirements after surgery, but it is not a standard use for this combination.","evidence":"Limited"}]
Primary treatment for: Electrolyte imbalance (hypomagnesemia and hypokalemia)
Also treats: Cardiac arrhythmias, Severe asthma, Preeclampsia, Digitalis toxicity
📋 Drug Information
| Generic Name(s) | Magnesium Carbonate (162.65mg) + Potassium Chloride (59.65mg) |
| Brand Name | plegiocard injection |
| Manufacturer | Samarth Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | |
| Route of Administration | Parenteral (intravenous injection or infusion) |
| Storage | Store at room temperature (15-30°C). Protect from light and freezing. Keep in the original container until use. |
| Shelf Life | Not established from the available information. Check the expiry date on the label. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Magnesium carbonate and potassium chloride work by replenishing two key electrolytes. Magnesium acts as a natural calcium channel blocker, helps regulate sodium-potassium ATPase, and stabilizes nerve and muscle cell membranes. Potassium chloride directly increases potassium levels, which are needed for repolarization of cardiac cells and for normal muscle contraction. Together they restore the electrical balance across cell membranes, support normal heart rhythm, and improve nerve signal transmission.
Mechanism Steps
💡 How to Take plegiocard injection
Strength: Injection containing Magnesium Carbonate 162.65 mg and Potassium Chloride 59.65 mg per unit.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the patient's magnesium and potassium levels, kidney function, heart condition, and the reason for treatment. It is given as a slow intravenous injection or infusion in a hospital or clinic. Typical doses range from one to several ampoules per day, but the exact amount must be determined by the doctor. Never self-administer this medicine. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may need lower doses because kidney function often declines with age. Close monitoring of magnesium and potassium levels is required. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with kidney impairment, the dose must be reduced or avoided. Close monitoring of serum magnesium and potassium is essential. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | No specific dose adjustment is established for liver disease, but monitoring is advised. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | Not established from the available information. The maximum dose depends on the patient's clinical condition and blood levels, and must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of plegiocard injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| ACE inhibitors | Major | |
| Digoxin | Major | |
| Neuromuscular blockers | Major | |
| Calcium channel blockers | Moderate | |
| Loop diuretics | Moderate | |
| Aminoglycosides | Moderate | |
| Antacids with magnesium | Minor | |
| Laxatives with magnesium | Minor | |
| Potassium supplements | Major |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone)
- ACE inhibitors and ARBs
- Digoxin
- Neuromuscular blockers
⚡ Moderate Interactions
- Calcium channel blockers
- Loop diuretics (e.g., furosemide)
- Aminoglycoside antibiotics
🍷 Alcohol Interaction
Alcohol can worsen dehydration and electrolyte imbalance. It is best to avoid alcohol while receiving this medicine and until your electrolyte levels are stable.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe kidney failure or anuria","Hyperkalemia (high potassium levels)","Hypermagnesemia (high magnesium levels)","Heart block (second or third degree) without a pacemaker","Severe dehydration or shock","Known allergy to any component"]
⚠️ Warnings & Precautions
["Must be given slowly to avoid sudden drops in blood pressure.","Use with caution in patients with kidney disease; dose reduction may be needed.","Monitor for signs of magnesium toxicity such as loss of deep tendon reflexes, respiratory depression, and confusion.","Monitor for signs of potassium toxicity such as irregular heartbeat and muscle weakness.","Do not use if the solution is discolored or contains particles.","Use with caution in patients taking digoxin or other heart medicines.","Elderly patients may be more sensitive to electrolyte changes."]
🤱 Lactation Safety
Magnesium and potassium are excreted in breast milk, but the amounts from a single injection are not expected to harm a nursing infant. Consult your doctor before receiving this medicine while breastfeeding.
💊 Overdose Management
Overdose can cause high magnesium and potassium levels, leading to slow heart rate, low blood pressure, confusion, muscle weakness, and difficulty breathing. Treatment includes stopping the injection, supporting breathing and circulation, and giving calcium gluconate for magnesium toxicity. Potassium levels may be lowered with insulin and glucose, sodium bicarbonate, or dialysis in severe cases. Immediate medical attention is required.
⏰ Missed Dose
This medicine is given by a healthcare professional in a controlled setting. Missed doses are not applicable for home use. If you miss a scheduled injection, contact your doctor or clinic to reschedule as soon as possible.
Additional Safety Advice
This medicine must only be given by a doctor or nurse in a clinic or hospital. Do not try to use it at home. Before receiving this injection, tell your doctor about all your medicines, especially water pills, blood pressure medicines, heart medicines, and any antibiotics. Also tell your doctor if you have kidney problems, heart problems, or if you are pregnant or breastfeeding. Blood tests will be done to check your magnesium and potassium levels before and during treatment. The injection is given slowly to avoid sudden drops in blood pressure. If you feel dizzy, have a slow heartbeat, or notice muscle weakness during the injection, tell your nurse or doctor right away. Do not drive or operate heavy machines right after the injection until you feel fully alert. Keep all follow-up appointments so your doctor can adjust your treatment safely.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have kidney impairment and heart disease, so they need lower doses and closer monitoring. Watch for confusion, weakness, and slow heart rate.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor. This medicine is used in pregnancy only when clearly needed, such as in preeclampsia. It is not a routine supplement for pregnancy planning.
🏥 Post-Surgery Considerations
After surgery, electrolyte imbalances are common. This medicine may be used to correct low magnesium and potassium. Your surgical team will monitor your levels and adjust the dose accordingly.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, especially if you have heart conditions. No specific precautions are required for dental work, but your dentist may consult your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until your electrolyte levels are stable and your doctor says it is safe. Mild activity like walking is usually fine, but listen to your body and stop if you feel dizzy or weak.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
After receiving this injection, you may feel dizzy or tired for a few hours. Do not drive or operate heavy machinery until you feel fully alert. Most people can return to normal activities the same day or the next day, depending on their condition.
🛑 When to Stop This Medicine
This medicine is stopped when your magnesium and potassium levels are back to normal and your symptoms have improved. Your doctor will decide when to stop based on blood tests. Do not stop treatment on your own.
📅 Long-Term Use Effects
Long-term use of this injection is not common because it is typically given for short periods to correct severe deficiencies. Prolonged use can lead to high magnesium or potassium levels, especially in kidney disease. Regular monitoring of blood levels and kidney function is required. If you need long-term electrolyte support, your doctor may switch you to oral supplements.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Used for mild deficiencies or after initial correction with injections.
Evidence: Well-establishedIncreasing intake of foods rich in magnesium and potassium can help maintain normal levels.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction with vaccines is known. However, if you are scheduled for vaccination, inform your doctor that you are receiving this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from direct sunlight
❌ DON'T
Do not use if the solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic, so travel advice is limited. If you are prescribed this injection during travel, carry it in its original packaging with a copy of your prescription. Keep it at room temperature and protect it from light and freezing. Inform airport security about your medical condition and carry a doctor's letter. Plan ahead for time zone changes if you need scheduled doses, and arrange for a healthcare professional to administer it at your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects begin within minutes after the injection, especially on heart rhythm and blood pressure. However, your electrolyte levels may take longer to fully normalize.
A: No, this medicine must be given by a healthcare professional in a hospital or clinic with proper monitoring.
A: Signs include slow heartbeat, confusion, extreme muscle weakness, and difficulty breathing. Tell your doctor immediately if you experience any of these.
A: Usually not. Once your levels are corrected, you may be switched to oral supplements. Your doctor will decide based on your condition.
🤔 Common Patient Concerns
🔄 Substitutes for plegiocard injection
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken as a supplement at home.
Fact: No, it is an injectable medicine that must be given by a healthcare professional in a medical setting. - Myth: It is safe for everyone with low energy.
Fact: It is only for patients with confirmed low magnesium and potassium levels, and it is not safe for people with kidney or heart conditions without careful monitoring. - Myth: More is always better for electrolyte balance.
Fact: Too much magnesium or potassium can be dangerous and even life-threatening, so doses must be carefully controlled.
🔄 Alternative Options
Generic Alternatives
- Magnesium carbonate and potassium chloride injection (generic)
Brand Alternatives
- Plegiocard Injection