pedycyp syrup - Cyproheptadine (2mg) + Tricholine Citrate (275mg) medicine

Kemlactin Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety

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🏭 Comex Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for appetite stimulation; well-established for antihistamine effects.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe drowsiness or difficulty staying awake
  • Confusion, hallucinations, or unusual behavior
  • Rapid, irregular, or pounding heartbeat
  • Difficulty urinating or inability to urinate
  • Swelling of face, lips, tongue, or throat
  • Yellowing of skin or eyes
  • Seizures or convulsions
  • Severe abdominal pain or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is pedycyp syrup used for?

This medicine is a combination of cyproheptadine and tricholine citrate used to stimulate appetite and promote weight gain in individuals with poor appetite or unexplained weight loss. It works by blocking histamine and serotonin receptors in the brain, which can increase hunger. It is also used for allergic conditions. It should be taken under medical supervision and is not recommended for newborns, patients with glaucoma, or those with urinary retention.

  • Generic Name: Cyproheptadine (2mg) + Tricholine Citrate (275mg)
  • Manufacturer: Comex Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 pedycyp syrup के बारे में (Hindi Summary)

उपयोग: यह दवा साइप्रोहेप्टाडाइन और ट्राइकोलीन सिट्रेट का संयोजन है, जिसका उपयोग भूख बढ़ाने और वजन बढ़ाने के लिए किया जाता है। यह उन लोगों के लिए फायदेमंद है जिनकी भूख कम है या जिनका वजन अचानक कम हो गया है। यह एलर्जी, जैसे नाक बहना, छींक आना और खुजली में भी राहत देती है। यह दवा मस्तिष्क में हिस्टामिन और सेरोटोनिन रिसेप्टर्स को ब्लॉक करके भूख को बढ़ाती है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना, धुंधली दृष्टि और कब्ज शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में तेज नींद, भ्रम, मतली, दिल की धड़कन तेज होना, पेशाब में रुकावट और एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसकी मात्रा या अवधि को बढ़ाएँ नहीं। इस दवा को लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आपको ग्लूकोमा, अस्थमा, पेशाब में रुकावट, लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। बच्चों और गर्भवती महिलाओं में इसका उपयोग डॉक्टर की सलाह के बिना न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 pedycyp syrup Uses & Benefits

[{"condition":"Appetite stimulation and weight gain","description":"Used to stimulate appetite in patients with poor appetite, cachexia, or unexplained weight loss.","evidence":"Well-established for cyproheptadine; tricholine citrate is adjunctive."},{"condition":"Allergic conditions","description":"Cyproheptadine component provides antihistamine relief for allergic rhinitis, urticaria, and itching.","evidence":"Well-established for cyproheptadine."},{"condition":"Nausea and vomiting","description":"Cyproheptadine has antiemetic properties and may help reduce nausea.","evidence":"Moderate evidence."}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Cyproheptadine is sometimes used off-label to prevent migraines, especially in children.","evidence":"Limited"},{"condition":"Serotonin syndrome","description":"Cyproheptadine has been used off-label as an antidote for serotonin syndrome.","evidence":"Case reports only"}]

Primary treatment for: Poor appetite and weight loss

Also treats: Allergic rhinitis, Urticaria, Nausea and vomiting

📋 Drug Information

Generic Name(s)Cyproheptadine (2mg) + Tricholine Citrate (275mg)
Brand Namepedycyp syrup
ManufacturerComex Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine before meals to maximize its appetite-stimulating effect.
2
Use a calibrated measuring spoon or cup to ensure accurate dosing.
3
Avoid driving or operating heavy machinery until you know how this medicine affects you.
4
Do not consume alcohol while taking this medicine, as it can increase drowsiness.
5
Monitor weight gain and report excessive or unwanted weight gain to your doctor.
6
Consult your doctor if you experience persistent drowsiness, dry mouth, or constipation.
7
Do not use this medicine for longer than prescribed without medical supervision.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Poor appetite
This medicine is commonly prescribed for this.
Likely Use
Unexplained weight loss
This medicine may be prescribed to promote weight gain.
Likely Use
Allergic rhinitis
Cyproheptadine component provides antihistamine relief.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCyproheptadine is well absorbed from the gastrointestinal tract after oral administration. Tricholine citrate is also absorbed orally. Specific absorption data for the combination syrup is not established from the available information.
DistributionCyproheptadine is widely distributed in the body, including the central nervous system. It crosses the blood-brain barrier and placenta, and is excreted in breast milk. Distribution data for tricholine citrate is not established from the available information.
Protein BindingCyproheptadine is approximately 96% bound to plasma proteins. Protein binding of tricholine citrate is not established from the available information.
MetabolismCyproheptadine undergoes extensive hepatic metabolism, primarily through glucuronidation. Tricholine citrate is metabolized to choline and citrate. Specific metabolic pathways for the combination are not established from the available information.
Half-LifeThe elimination half-life of cyproheptadine is approximately 8 hours. The half-life of tricholine citrate is not established from the available information.
ExcretionCyproheptadine and its metabolites are excreted primarily in urine and to a lesser extent in feces. Tricholine citrate metabolites are excreted in urine and exhaled as carbon dioxide.
BioavailabilityBioavailability of cyproheptadine is approximately 30-40% due to first-pass metabolism. Bioavailability of tricholine citrate is not established from the available information.
Onset of ActionAppetite stimulation may begin within a few days of starting therapy. Antihistamine effects occur within 1-2 hours. Full effects on weight gain may take several weeks.
Peak Plasma TimePeak plasma concentration of cyproheptadine is reached within 1-2 hours after oral administration. Peak plasma time for tricholine citrate is not established from the available information.
Duration of ActionThe antihistamine effect of cyproheptadine lasts approximately 4-8 hours. Appetite-stimulating effects may persist with continued dosing. Duration of tricholine citrate action is not established from the available information.

How It Works

Cyproheptadine is a first-generation antihistamine that competitively blocks histamine H1 receptors and also antagonizes serotonin 5-HT2 receptors. Its appetite-stimulating effect is thought to be mediated through serotonin antagonism in the hypothalamus, which can increase hunger. Tricholine citrate is a choline salt of citric acid that acts as a bile acid sequestrant, binding bile acids in the intestine and potentially improving fat digestion and absorption. The combination is intended to enhance appetite and nutritional status.

Mechanism Steps

1
Histamine H1 receptor blockade: Cyproheptadine binds to H1 receptors, preventing histamine from causing allergic symptoms such as itching, sneezing, and vasodilation.
2
Serotonin 5-HT2 receptor antagonism: Cyproheptadine blocks serotonin receptors in the brain, which can reduce nausea and stimulate appetite, possibly by affecting satiety centers.
3
Anticholinergic effects: Cyproheptadine also has anticholinergic properties, which can cause dry mouth, constipation, and urinary retention.
4
Bile acid sequestration: Tricholine citrate binds bile acids in the gut, potentially enhancing fat digestion and absorption, and may support liver function.

💡 How to Take pedycyp syrup

Strength: Each 5 mL of syrup contains Cyproheptadine 2 mg and Tricholine Citrate 275 mg.

1Shake the bottle well before each use.
2Use a calibrated measuring spoon or cup to measure the prescribed dose.
3Take the medicine orally, preferably before meals to enhance appetite stimulation.
4Swallow the syrup directly; do not mix with large amounts of water unless instructed.
5Follow the prescribed schedule consistently.
6Do not exceed the recommended dose or duration without medical advice.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1 to 2 teaspoons (5 mL to 10 mL) two to three times daily, preferably before meals. However, the exact dose and duration must be individualized by a qualified clinician based on the patient's age, weight, indication, and renal and hepatic function. Do not self-adjust the dose. Follow your doctor's instructions carefully.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the anticholinergic and sedative effects of cyproheptadine. Use with caution and consider lower initial doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be necessary in patients with renal impairment. Consult a healthcare provider for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be required. Consult a healthcare provider for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take before meals
Enhances appetite stimulation.
Alcohol
Avoid
Increases drowsiness and CNS depression.
Grapefruit juice
Avoid excessive intake
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of pedycyp syrup

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (10-15%))
Sip water frequently, chew sugar-free gum, or use saliva substitutes.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid sudden movements.
Constipation (Common (5-10%))
Increase dietary fiber and fluid intake. Consult doctor if severe.
Blurred vision (Uncommon (1-5%))
Usually temporary. Avoid driving if vision is affected.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Blood dyscrasias (e.g., agranulocytosis, hemolytic anemia) (Rare (<0.1%))
Report unusual bruising, bleeding, fever, or sore throat to your doctor immediately.
Liver dysfunction (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or abdominal pain.
Seizures (Rare (<0.1%))
Discontinue and seek emergency care if seizures occur.

⚠️ Rare Side Effects

Hallucinations
Contact your doctor immediately if you experience hallucinations or confusion.
Urinary retention
Seek medical attention if you are unable to urinate.
Photosensitivity
Use sunscreen and protective clothing when outdoors.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
CNS depressants Major
Anticholinergics Major
SSRIs Moderate
Beta-blockers Moderate
Levodopa Moderate
Antacids Minor
Corticosteroids Minor

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)

⚡ Moderate Interactions

  • SSRIs
  • Beta-blockers
  • Levodopa

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and impair motor skills. Combining alcohol with cyproheptadine may also increase the risk of respiratory depression and other central nervous system effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to cyproheptadine, tricholine citrate, or any component of the formulation","Newborns and premature infants","Narrow-angle glaucoma","Urinary retention","Severe asthma","Concurrent use with MAO inhibitors","Breastfeeding (relative contraindication)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, asthma, urinary retention, or prostatic hypertrophy.","May impair mental alertness in children.","Prolonged use may lead to excessive weight gain.","Not recommended for use in children under 2 years of age.","Consult doctor before use in pregnancy or breastfeeding."]

🤱 Lactation Safety

Cyproheptadine is excreted in breast milk and may cause drowsiness or other effects in the nursing infant. It is not recommended for use during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, hallucinations, seizures, respiratory depression, and cardiovascular collapse. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not consume alcohol while taking this medicine, as it can increase drowsiness and impair judgment. Inform your doctor if you have a history of glaucoma, asthma, urinary retention, liver disease, or kidney disease. This medicine may interact with other medications, including sedatives, antidepressants, and antihistamines, so always disclose all medicines you are taking. Do not use this medicine for weight gain without addressing underlying nutritional and lifestyle factors. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to the anticholinergic and sedative effects of this medicine. Use with caution and lower doses may be required. Monitor for confusion, urinary retention, and falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Discuss potential risks and benefits with your healthcare provider.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to stimulate appetite during recovery. However, consult your surgeon before taking it, as it may interact with other postoperative medications.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental caries. Maintain good oral hygiene and stay hydrated. Inform your dentist if you are taking this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Eat small, frequent meals to stimulate appetite.
🥗
Include nutrient-dense foods like nuts, dairy, and lean proteins.
😴
Stay physically active to improve overall health and appetite.
💧
Get adequate sleep to support recovery and weight gain.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Avoid skipping meals and maintain a regular eating schedule.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light to moderate exercise is generally safe and can complement appetite stimulation.

🥗 Diet Recommendations

Include high-calorie, nutrient-rich foods like avocados, nuts, and whole grains.
Drink smoothies or shakes between meals for extra calories.
Add healthy fats like olive oil and ghee to meals.
Eat protein-rich foods to support muscle mass.
Stay hydrated but avoid drinking large amounts of water before meals.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Do not stop taking this medicine abruptly without consulting your doctor. Your doctor will advise you on the appropriate duration and tapering schedule if needed. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to excessive weight gain, persistent drowsiness, and anticholinergic effects. Regular monitoring of weight, liver function, and blood counts may be advised. It should be used for the shortest duration necessary and under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary counseling

A nutritionist can help create a high-calorie, nutrient-rich diet plan.

Evidence: Well-established
Physical therapy

Can help improve appetite and overall health through regular exercise.

Evidence: Moderate
Treating underlying conditions

Addressing the root cause of poor appetite, such as depression or gastrointestinal disorders.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with unexplained weight loss and poor appetite
She was prescribed this medicine by her doctor after a thorough evaluation. She started taking it before meals as directed. Within two weeks, her appetite improved significantly, and she began to regain weight. She reported mild drowsiness initially, which subsided after a few days. She emphasized the importance of taking it consistently and following a nutritious diet.
💡 Lesson: Consistent use as prescribed, along with a balanced diet, can lead to improved appetite and healthy weight gain.
👤 A 50-year-old man recovering from a prolonged illness with loss of appetite
After a severe infection, he had lost a lot of weight and had no desire to eat. His doctor prescribed this medicine. He noticed an increase in hunger within a week. He also experienced dry mouth, which he managed by drinking water frequently. He completed the prescribed course and regained his strength.
💡 Lesson: This medicine can be effective for appetite stimulation during recovery, but side effects like dry mouth should be managed with adequate hydration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Appetite stimulation may begin within a few days, but noticeable weight gain may take several weeks.

Q: Can I take this medicine without a prescription?

A: No, this medicine is a prescription drug and should only be taken under medical supervision.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than half the dosing interval has passed; otherwise, skip it and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for pedycyp syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for weight gain without any dietary changes.
    Fact: This medicine stimulates appetite but should be combined with a balanced diet and healthy lifestyle for optimal results.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for individuals with certain conditions like glaucoma, urinary retention, or asthma, and should be used only under medical supervision.
  • Myth: You can stop taking this medicine abruptly without consulting a doctor.
    Fact: Always consult your doctor before stopping this medicine, as abrupt discontinuation may lead to withdrawal effects or return of symptoms.

🔄 Alternative Options

Generic Alternatives

  • Cyproheptadine + Tricholine Citrate syrup (generic)

Brand Alternatives

  • Kemlactin Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cyproheptadine 2mg + Tricholine Citrate 275mg per 5mL","uses":"Appetite stimulation, weight gain, allergies","notes":"Combination product"},{"medicine":"Cyproheptadine alone","composition":"Cyproheptadine only","uses":"Appetite stimulation, allergies","notes":"No tricholine citrate"}]

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