acirox 500mg tablet - Ciprofloxacin (500mg) medicine

Acirox 500mg Tablet - Uses, Price, Side Effects

4.5 (15 reviews)

Ciprofloxacin (500mg)

🏭 Comex Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is acirox 500mg tablet used for?

Acirox 500mg Tablet contains Ciprofloxacin, a fluoroquinolone antibiotic that treats bacterial infections by stopping bacteria from multiplying. It is used for urinary tract infections, respiratory infections, gastrointestinal infections, and skin infections. Take as prescribed, usually twice daily, with or without food. Avoid antacids within 2 hours.

Generic Name: Ciprofloxacin
Manufacturer: Comex Pharma
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 acirox 500mg tablet Uses & Benefits

Urinary tract infections, respiratory tract infections, skin and soft tissue infections, bone and joint infections, gastrointestinal infections, septicemia, and anthrax.

Off-label uses: Prostatitis, epididymitis, pelvic inflammatory disease, and some mycobacterial infections.

📋 Drug Information

Generic Name(s)	Ciprofloxacin
Brand Name	Alciflox 500mg Tablet
Manufacturer	Comex Pharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Quinolones/ Fluroquinolones
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and well absorbed from the gastrointestinal tract after oral administration.

DistributionWidely distributed throughout the body; high concentrations in tissues and fluids including lung, sinus, bone, prostate, and urine.

Protein Binding20-40%

MetabolismPartially metabolized in the liver; produces four metabolites (desethylene-, sulfonyl-, oxo-, and N-formylciprofloxacin).

Half-Life4 hours (range 3-5 hours)

ExcretionPrimarily excreted unchanged in urine (50-70%) via glomerular filtration and tubular secretion; also in feces (15-25%).

Bioavailability70-80%

Onset of Action1-2 hours

Peak Plasma Time1-2 hours

Duration of Action12 hours

How It Works

Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventing DNA replication, transcription, repair, and recombination.

Mechanism Steps

1Ciprofloxacin enters bacterial cell via porin channels.

2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV.

3Inhibits the resealing of DNA strands after cleavage.

💡 How to Take acirox 500mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of acirox 500mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Insomnia
Abdominal pain

🚨 Serious Side Effects

Tendonitis or tendon rupture
Peripheral neuropathy
CNS effects (seizures, confusion)
QT prolongation
Clostridium difficile diarrhea
Hypersensitivity reactions

⚠️ Rare Side Effects

Hemolytic anemia
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Interstitial nephritis
Hepatitis
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
NSAIDs	Moderate	Increased risk of CNS stimulation and seizures
Theophylline	Moderate	Increased theophylline levels and toxicity
Antacids	Moderate	Reduced absorption of ciprofloxacin
Corticosteroids	Major	Increased risk of tendon rupture

🚨 Major Interactions

Tizanidine
Theophylline
Warfarin
Caffeine
NSAIDs

⚡ Moderate Interactions

Cyclosporine
Methotrexate
Phenytoin
Glyburide
Probenecid

ℹ️ Minor Interactions

Diazepam
Metoprolol
Omeprazole
Ranitidine

🍽️ Food Interactions

Dairy products, calcium-fortified juices, and antacids reduce absorption; avoid concurrent administration.

🍷 Alcohol Interaction

No direct interaction, but alcohol may increase CNS side effects like dizziness.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category C

🚫 Contraindications

Hypersensitivity to ciprofloxacin or any fluoroquinolone; concomitant use with tizanidine; history of tendon disorders related to fluoroquinolones.

📊 Monitoring Parameters

Renal function, hepatic function, blood counts, signs of tendonitis or tendon rupture, CNS effects, and QT interval if risk factors.

🤱 Lactation Safety

Excreted in breast milk; use with caution, potential for adverse effects in nursing infants.

💊 Overdose Management

Supportive care; monitor ECG for QT prolongation; consider activated charcoal if recent ingestion; hemodialysis removes only 10-20%.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for acirox 500mg tablet

View All

Alternative brands with exact same active ingredient (Ciprofloxacin (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026