Nyaibi Syrup: Complete Medicine Guide for Patients and Caregivers
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of face, lips, tongue, or throat, or difficulty breathing
- Severe drowsiness, confusion, or hallucinations
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Unusual bleeding or bruising, fever, or sore throat
- Palpitations, fainting, or chest pain
- Inability to pass urine
- Seizures or uncontrolled movements
If experiencing severe symptoms, call emergency services immediately.
What is nyaibi syrup used for?
This medicine is a combination of lysine and cyproheptadine used to treat allergic symptoms such as sneezing, runny nose, and itching, and to stimulate appetite. It works by blocking histamine and serotonin receptors. It is available as a syrup and should be taken only under a doctor's prescription.
- Generic Name: Lysine (150mg) + Cyproheptadine (2mg)
- Manufacturer: Ciron Drugs & Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nyaibi syrup के बारे में (Hindi Summary)
उपयोग: यह दवा लाइसिन और साइप्रोहेप्टाडीन का मिश्रण है, जिसका उपयोग एलर्जी के लक्षणों जैसे छींक, नाक बहना, खुजली और आंखों में पानी आना को कम करने के लिए किया जाता है। यह भूख बढ़ाने में भी मदद करती है, इसलिए इसे अक्सर उन बच्चों और बड़ों को दिया जाता है जिनकी भूख कम लगती है या वजन नहीं बढ़ रहा होता। यह दवा सिर्फ डॉक्टर के पर्चे पर ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना और पेट में हल्की गड़बड़ हो सकती है। कुछ लोगों में भूख बढ़ सकती है, जो अक्सर इच्छित प्रभाव होता है। कभी-कभी धुंधली दृष्टि, कब्ज, पेशाब करने में कठिनाई और नाक या गले में सूखापन हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर एलर्जी, सांस लेने में तकलीफ, पीलिया, या दिल की धड़कन में बदलाव महसूस हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बढ़ाएं। यह दवा नींद ला सकती है, इसलिए जब तक आपको इसका असर पता न चल जाए, वाहन न चलाएं और मशीनें न चलाएं। इस दवा के साथ शराब बिल्कुल न पिएं। बच्चों की पहुंच से दूर रखें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। अपनी सभी दवाओं और स्वास्थ्य समस्याओं की जानकारी डॉक्टर को दें। दवा को उसके मूल डिब्बे में, ठंडी और सूखी जगह पर, धूप से दूर रखें।
💊 nyaibi syrup Uses & Benefits
[{"condition":"Allergic rhinitis","description":"This medicine helps relieve sneezing, runny nose, nasal itching, and watery eyes caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria (hives)","description":"Cyproheptadine in this medicine reduces itching and skin rash associated with urticaria.","evidence":"Well-established"},{"condition":"Poor appetite and inadequate weight gain","description":"This medicine is commonly prescribed to stimulate appetite and support weight gain in children and adults with poor oral intake.","evidence":"Commonly used, evidence varies"},{"condition":"Pruritus (itching) due to various causes","description":"The antihistamine action of this medicine helps reduce itching in conditions such as insect bites, eczema, and drug rashes.","evidence":"Well-established"},{"condition":"Migraine prophylaxis","description":"Cyproheptadine may be used to reduce the frequency of migraine attacks in some patients, especially children.","evidence":"Limited to moderate"}]
Off-label uses: [{"condition":"Cyproheptadine for serotonin syndrome","description":"In hospital settings, cyproheptadine has been used as an antidote for serotonin syndrome, but this is a specialized off-label use.","evidence":"Limited"},{"condition":"Cyproheptadine for insomnia","description":"Because of its sedating effect, cyproheptadine is sometimes used off-label for short-term sleep problems, but this is not a recommended first-line use.","evidence":"Limited"},{"condition":"Lysine for herpes simplex prevention","description":"Lysine has been studied for reducing cold sore outbreaks, but evidence is mixed and this is not a primary use of this combination.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis and poor appetite
Also treats: Urticaria, Pruritus, Migraine prophylaxis, Poor weight gain in children
📋 Drug Information
| Generic Name(s) | Lysine (150mg) + Cyproheptadine (2mg) |
| Brand Name | nyaibi syrup |
| Manufacturer | Ciron Drugs & Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep the bottle tightly closed and protect it from direct sunlight and moisture. Do not freeze the syrup. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary components. Cyproheptadine is a first-generation antihistamine that blocks histamine H1 receptors, which reduces allergy symptoms such as sneezing, itching, and runny nose. It also blocks serotonin 5-HT2 receptors, which contributes to appetite stimulation and may help prevent migraines. In addition, cyproheptadine has anticholinergic properties that can cause dry mouth, blurred vision, and constipation. Lysine is an essential amino acid that supports protein synthesis, collagen formation, and nutritional status. When combined, lysine supports general nutrition and appetite while cyproheptadine provides the main antihistamine and appetite-stimulating effects.
Mechanism Steps
💡 How to Take nyaibi syrup
Strength: Each 5 mL of syrup contains lysine 150 mg and cyproheptadine 2 mg.
Dosage Information
| Adult Dosage | The adult dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, and liver and kidney function. For allergic conditions, a common starting dose is 2 mg to 4 mg of cyproheptadine every 6 to 8 hours, not exceeding 16 mg to 20 mg per day. For appetite stimulation, lower doses may be used. The syrup contains 2 mg of cyproheptadine and 150 mg of lysine per 5 mL. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing of this medicine is not established from available information for all age groups. It is contraindicated in newborns and premature infants. For children above 2 years, the dose is usually calculated by weight and prescribed by a pediatrician. Do not give this medicine to children without a doctor's prescription. Consult a pediatrician for exact dosing. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. The dose should be started low and increased gradually only if needed, under close medical supervision. Regular monitoring for confusion, falls, and urinary retention is advised. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney disease because cyproheptadine may accumulate. Consult a doctor for individualized dosing. |
| Hepatic Impairment | This medicine should be used with caution in patients with liver disease. Dose reduction or avoidance may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of cyproheptadine for adults is generally 16 mg to 20 mg per day, but this must be determined by a qualified clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nyaibi syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Tricyclic antidepressants | Major | |
| SSRIs | Moderate | |
| Beta-blockers | Moderate | |
| Metoclopramide | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor | |
| Opioid pain relievers | Major |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- CNS depressants (e.g., alcohol, benzodiazepines, opioids, sleeping pills)
- Anticholinergic drugs (e.g., atropine, benztropine, tricyclic antidepressants)
⚡ Moderate Interactions
- SSRIs (e.g., fluoxetine, sertraline)
- Beta-blockers (e.g., propranolol)
- Metoclopramide
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it can increase drowsiness, dizziness, and difficulty concentrating. Combining alcohol with this medicine can also increase the risk of falls and accidents. If you consume alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cyproheptadine, lysine, or any component of this medicine","Newborns and premature infants","Narrow-angle glaucoma","Bladder neck obstruction or symptomatic prostate enlargement","Severe liver disease","Concurrent use with MAO inhibitors","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not drink alcohol while taking this medicine.","Use with caution in elderly patients because they are more sensitive to sedation and anticholinergic effects.","Use with caution in patients with asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.","Do not stop this medicine suddenly after long-term use; taper gradually under medical supervision.","Keep out of reach of children; accidental overdose can be dangerous.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Cyproheptadine may pass into breast milk and could cause drowsiness in a breastfed infant. Breastfeeding mothers should consult their doctor before using this medicine. If used, monitor the infant for excessive sleepiness or poor feeding.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, confusion, hallucinations, rapid heartbeat, fever, flushing, and seizures. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal, intravenous fluids, and monitoring of vital signs. There is no specific antidote for cyproheptadine overdose, but physostigmine may be used in severe anticholinergic toxicity under medical supervision.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not increase the dose on your own, even if you feel the medicine is not working quickly enough. Because this medicine can cause drowsiness, avoid driving, cycling, or operating heavy machinery until you know how it affects you. Do not drink alcohol while taking this medicine, as alcohol can increase drowsiness and dizziness. Keep this medicine out of the reach of children. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before using this medicine. Inform your doctor about all other medicines, supplements, and herbal products you are taking, because this medicine can interact with many drugs. If you have glaucoma, prostate problems, asthma, liver disease, kidney disease, or heart disease, tell your doctor before starting this medicine. Do not stop this medicine suddenly if you have been taking it for a long time; your doctor will guide you on how to stop it safely. Store the syrup in its original container, tightly closed, at room temperature, and away from direct sunlight. Do not use the syrup after the expiry date printed on the pack.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. They may experience increased drowsiness, confusion, dry mouth, constipation, and urinary retention. The dose should be started low and increased gradually only if needed, with close monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Cyproheptadine is not recommended during pregnancy unless clearly needed. Your doctor may suggest alternative treatments.
🏥 Post-Surgery Considerations
After surgery, this medicine should be used with caution because it can increase sedation and interact with anesthetic agents and pain medicines. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental problems. Inform your dentist that you are taking this medicine before any dental procedure. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Because this medicine can cause drowsiness and dizziness, avoid strenuous exercise or activities that require full alertness until you know how the medicine affects you. If you exercise, do so in a safe environment and stop if you feel dizzy or unusually tired.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks that require concentration. It is best to avoid these activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about adjusting the dose or timing.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or if the medicine is no longer needed, your doctor will advise you on how to stop it safely, especially if you have been taking it for a long time.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance to its sedative effects, weight gain, and rarely blood disorders or liver problems. Regular monitoring of weight, blood counts, and liver function may be advised by your doctor. It is important to review the need for continued use periodically and to taper the dose gradually if stopping after long-term use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to allergens can help manage allergic symptoms without medicine.
Evidence: Well-establishedA dietitian can help improve appetite and weight gain through dietary changes.
Evidence: Well-establishedThese may be used for allergies with less sedation, but they do not stimulate appetite.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case customs or security asks for it. Keep the syrup in a cool, dry place, away from direct sunlight. If you are crossing time zones, continue taking the medicine at the same intervals as prescribed, but consult your doctor if you need to adjust the schedule. Do not leave the medicine in a hot car or checked luggage. If you are traveling for a long time, carry enough supply to last the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose. Appetite stimulation may take a few days to become noticeable.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: This medicine is not safe for newborns or premature infants. For older children, it should only be given under a pediatrician's supervision with the correct dose.
A: Do not stop this medicine suddenly if you have been taking it for a long time. Your doctor will guide you on how to taper it safely.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for nyaibi syrup
View AllAlternative brands with exact same active ingredient:
-
cadictin l syrupMediwin Pharmaceuticals ₹39.50 12.6% CHEAPER
-
cyptone l syrupNumed ₹89.06 97% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a general tonic for all children.
Fact: This medicine is a prescription drug and should only be used for specific indications such as allergies or poor appetite, not as a general tonic. - Myth: This medicine can be taken long-term without any monitoring.
Fact: Long-term use requires medical supervision and monitoring for side effects such as sedation, weight gain, and rare blood or liver problems. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be strictly avoided because it increases drowsiness and dizziness.
🔄 Alternative Options
Generic Alternatives
- Cyproheptadine hydrochloride syrup
- Lysine hydrochloride syrup
Brand Alternatives
- Ciplactin
- Practin