nova ventiphylline forte tablet - Salbutamol (4mg) + Theophylline (200mg) medicine

Nova Ventiphylline Forte Tablet: Complete Medicine Guide

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🏭 Yash Pharma Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or pressure
  • Irregular or very fast heartbeat
  • Difficulty breathing that does not improve with rescue inhaler
  • Seizures or convulsions
  • Swelling of face, lips, or throat
  • Severe nausea, vomiting, or stomach pain
  • Muscle weakness or cramps

If experiencing severe symptoms, call emergency services immediately.

What is nova ventiphylline forte tablet used for?

This medicine is a combination of Salbutamol and Theophylline used to treat asthma and COPD by relaxing the muscles in the airways to make breathing easier. It is taken orally, usually after food, and must be prescribed by a doctor.

  • Generic Name: Salbutamol (4mg) + Theophylline (200mg)
  • Manufacturer: Yash Pharma Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nova ventiphylline forte tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सल्ब्यूटामोल और थियोफिलीन का संयोजन है, जिसका उपयोग अस्थमा और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) में सांस लेने में आसानी के लिए किया जाता है। यह वायुमार्ग की मांसपेशियों को ढीला करके घरघराहट, सीने में जकड़न और सांस फूलने जैसे लक्षणों को कम करती है। इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथ कांपना, घबराहट, सिरदर्द, धड़कन तेज होना और पेट में गड़बड़ी शामिल हैं। कुछ लोगों को मतली या उल्टी भी हो सकती है। गंभीर दुष्प्रभाव कम होते हैं, लेकिन दिल की धड़कन अनियमित होना, सीने में दर्द, या एलर्जी की प्रतिक्रिया हो सकती है। अगर कोई भी दुष्प्रभाव लंबे समय तक बना रहे, तो डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के बाद पानी के साथ निगलें। शराब का सेवन न करें क्योंकि इससे दिल की धड़कन अनियमित हो सकती है। बिना डॉक्टर की सलाह के कोई अन्य दवा न लें। अगर आपको दिल, किडनी, या लीवर की बीमारी है, तो डॉक्टर को बताएं। अचानक सांस फूलने पर इस दवा का इस्तेमाल न करें, बल्कि अपने रेस्क्यू इनहेलर का उपयोग करें और तुरंत मदद लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 nova ventiphylline forte tablet Uses & Benefits

[{"condition":"Bronchial asthma","description":"Used as maintenance therapy to prevent and relieve bronchospasm in adults and older children with reversible airway obstruction.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps reduce breathlessness and wheezing in patients with chronic bronchitis or emphysema when used as part of a comprehensive treatment plan.","evidence":"Established"},{"condition":"Exercise-induced bronchospasm","description":"May be prescribed to prevent narrowing of airways triggered by physical activity in some patients.","evidence":"Limited"},{"condition":"Nocturnal asthma","description":"Sometimes used to reduce nighttime wheezing and cough in patients whose symptoms worsen at night.","evidence":"Limited"}]

Off-label uses: [{"condition":"Apnea of prematurity","description":"Theophylline has been used off-label in newborns to stimulate breathing, but this is not a standard use for the oral combination tablet.","evidence":"Limited"},{"condition":"Severe bronchospasm in intensive care","description":"Intravenous forms of these agents may be used in hospital settings, but the oral tablet is not intended for emergency care.","evidence":"Limited"}]

Primary treatment for: Bronchial asthma

Also treats: Chronic obstructive pulmonary disease (COPD), Chronic bronchitis, Emphysema

📋 Drug Information

Generic Name(s)Salbutamol (4mg) + Theophylline (200mg)
Brand Namenova ventiphylline forte tablet
ManufacturerYash Pharma Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information. The World Health Organization does not specifically recommend this fixed-dose combination for routine use; treatment should follow national asthma and COPD guidelines.
ICMR GuidelineNot established from the available information. The Indian Council of Medical Research guidelines for asthma and COPD management should be consulted for appropriate use.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after food to reduce stomach upset.
2
Do not use this medicine for sudden severe breathing difficulty; use your rescue inhaler.
3
Avoid caffeine and alcohol while taking this medicine.
4
Monitor your heart rate and report any palpitations or irregular heartbeat.
5
Keep a diary of your symptoms and peak flow readings to share with your doctor.
6
Do not stop this medicine suddenly without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for wheezing due to asthma or COPD.
Likely Use
✅
Chest tightness
It helps relax airway muscles and relieve chest tightness.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Sore throat
This medicine is not used for throat infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalbutamol is well absorbed from the gastrointestinal tract after oral administration, although oral bioavailability is lower than with inhaled routes due to first-pass metabolism. Theophylline is also rapidly and completely absorbed from the gastrointestinal tract when given as an immediate-release tablet. Food may slightly affect the rate but not the extent of absorption of Theophylline.
DistributionSalbutamol distributes widely into body tissues and crosses the placenta. Theophylline distributes into extracellular fluid and tissues, with a volume of distribution of approximately 0.5 L/kg in adults. Both agents can cross the blood-brain barrier to some extent, which explains some central nervous system effects.
Protein BindingSalbutamol is approximately 10% bound to plasma proteins. Theophylline is about 40% bound to plasma proteins in adults, and this binding may be lower in newborns and in patients with liver disease.
MetabolismSalbutamol undergoes extensive first-pass metabolism in the liver, mainly by sulfation to an inactive sulfate conjugate. Theophylline is metabolized in the liver by cytochrome P450 enzymes, primarily CYP1A2 and CYP3A4, to inactive metabolites including 1,3-dimethyluric acid and 3-methylxanthine.
Half-LifeThe elimination half-life of Salbutamol is approximately 4 to 6 hours. Theophylline has a variable half-life ranging from 3 to 12 hours in healthy adults, but it can be longer in patients with liver disease, heart failure, or in the elderly, and shorter in smokers.
ExcretionSalbutamol and its metabolites are excreted mainly in the urine, with a smaller fraction in the feces. Theophylline metabolites are excreted primarily in the urine, and about 10% of Theophylline is excreted unchanged in the urine.
BioavailabilityThe oral bioavailability of Salbutamol is approximately 40% due to first-pass metabolism. Theophylline has a high oral bioavailability of about 96% when taken as an immediate-release formulation.
Onset of ActionSalbutamol begins to act within 15 to 30 minutes after oral intake. Theophylline has a slower onset, typically within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations of Salbutamol are reached in about 2 to 4 hours after oral dosing. Theophylline peaks in about 1 to 2 hours for immediate-release tablets.
Duration of ActionThe bronchodilator effect of Salbutamol lasts about 4 to 6 hours. Theophylline provides a longer duration of action, typically 6 to 12 hours depending on the dose and individual metabolism.

How It Works

This medicine works through two complementary mechanisms. Salbutamol selectively stimulates beta-2 adrenergic receptors on the smooth muscle cells of the airways, which increases cyclic AMP levels and causes the muscles to relax, thereby widening the bronchial tubes. Theophylline, a methylxanthine, inhibits phosphodiesterase enzymes and blocks adenosine receptors, which also raises cyclic AMP and leads to bronchial smooth muscle relaxation. In addition, Theophylline improves the strength of the diaphragm, stimulates the respiratory center in the brain, and reduces the release of inflammatory mediators from mast cells. The combined effect is a rapid and sustained opening of the airways, making it easier for the patient to breathe.

Mechanism Steps

1
Salbutamol binds beta-2 receptors: Salbutamol attaches to beta-2 adrenergic receptors on airway smooth muscle cells and triggers a signaling cascade.
2
Increased cyclic AMP: This binding activates adenylate cyclase, which raises intracellular cyclic AMP levels and promotes muscle relaxation.
3
Theophylline inhibits phosphodiesterase: Theophylline blocks phosphodiesterase enzymes that normally break down cyclic AMP, so cyclic AMP remains elevated for longer.
4
Adenosine receptor blockade: Theophylline also blocks adenosine receptors, which prevents adenosine-mediated bronchoconstriction and mast cell activation.
5
Bronchodilation and symptom relief: The combined rise in cyclic AMP and receptor blockade relaxes airway smooth muscle, reduces inflammation, and improves airflow.

💡 How to Take nova ventiphylline forte tablet

Strength: Each immediate-release tablet contains Salbutamol 4 mg and Theophylline 200 mg.

1Swallow the tablet whole with a glass of water.
2Take it after food to reduce stomach upset.
3Do not crush, chew, or break the tablet unless your doctor advises.
4Follow the same times each day to maintain steady blood levels.
5If you have trouble swallowing, ask your doctor about alternative formulations.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times a day, but the exact dose and frequency depend on the patient's condition, response to treatment, and Theophylline blood levels. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Your doctor may start with a lower dose and gradually increase it to minimize side effects.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may require lower doses because of reduced liver and kidney function, and they are more sensitive to the side effects of Theophylline. Close monitoring is recommended.
Renal ImpairmentDose adjustment may be needed in patients with severe renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentDose reduction is often necessary in patients with liver disease because Theophylline clearance is reduced. Close monitoring of Theophylline levels is advised.
Maximum Daily DoseThe maximum daily dose should not exceed the limit prescribed by your doctor. For Theophylline, the usual maximum is 10 mg/kg per day, but this must be confirmed by a clinician. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Caffeine-containing drinks
Limit or avoid
May increase nervousness, tremor, and palpitations.
High-fat meals
Take with caution
May affect Theophylline absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nova ventiphylline forte tablet

✅ Common Side Effects

Tremor (Common (5-10%))
Usually reduces with continued use. Avoid caffeine and report if it interferes with daily activities.
Palpitations (Common (5-10%))
Monitor your pulse. If it feels very fast or irregular, contact your doctor.
Nervousness or restlessness (Common (5-10%))
Try relaxation techniques. If it persists, speak to your doctor about dose adjustment.
Headache (Common (5-10%))
Stay hydrated and rest. Consult a doctor if the headache is severe or persistent.
Nausea or stomach upset (Common (5-10%))
Take the tablet with food or milk to reduce stomach irritation.

🚨 Serious Side Effects

Irregular heartbeat (arrhythmia) (Uncommon (0.1-1%))
Seek immediate medical attention if you feel a racing, fluttering, or irregular heartbeat.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you develop swelling of the face, lips, or throat, or difficulty breathing.
Seizures (Rare (<0.1%))
This can occur with high Theophylline levels. Seek emergency care immediately if a seizure occurs.
Severe hypokalemia (low potassium) (Uncommon (0.1-1%))
Report muscle weakness, cramps, or palpitations to your doctor for blood tests.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if you are diabetic and inform your doctor.
Lactic acidosis
Seek medical help if you experience rapid breathing, confusion, or extreme fatigue.
Skin rash
Stop the medicine and consult a doctor if a rash appears.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Propranolol Major
Erythromycin Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Cimetidine Minor
Phenytoin Minor
Caffeine Minor
Alcohol Moderate

🚨 Major Interactions

  • Ciprofloxacin
  • Propranolol
  • Erythromycin

⚡ Moderate Interactions

  • Furosemide
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of irregular heartbeat, worsen stomach irritation, and may affect Theophylline metabolism, leading to unpredictable blood levels. It can also add to central nervous system side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Salbutamol, Theophylline, or any component of the tablet","Active peptic ulcer disease","Uncontrolled cardiac arrhythmias","Acute porphyria","Severe liver disease","Uncontrolled hyperthyroidism"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, high blood pressure, or arrhythmias.","Monitor potassium levels, especially if taking diuretics or corticosteroids.","Avoid in patients with a history of seizures unless benefits outweigh risks.","Do not use for acute severe asthma attacks; use a rescue inhaler instead.","Theophylline has a narrow therapeutic index; dose adjustments are critical.","Elderly patients and those with liver or heart disease may need lower doses.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Salbutamol and Theophylline are excreted in breast milk in small amounts. Theophylline can cause irritability or insomnia in a nursing infant. Breastfeeding mothers should consult their doctor before using this medicine.

💊 Overdose Management

Overdose of this medicine can cause severe tachycardia, arrhythmias, seizures, and hypokalemia. If overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal, intravenous fluids, and management of seizures and arrhythmias. Theophylline levels should be measured, and the patient should be monitored in a hospital setting.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop it without medical advice. Swallow the tablet whole with a glass of water, preferably after food to reduce stomach upset. Avoid drinking alcohol while taking this medicine because it can increase the risk of irregular heartbeat and stomach irritation. Do not take other medicines for asthma, cold, or cough without asking your doctor, as many of them can interact with this product. If you have heart disease, high blood pressure, thyroid problems, liver disease, or kidney disease, tell your doctor before starting this medicine. Keep all follow-up appointments so your doctor can monitor your heart rate, breathing, and blood levels of Theophylline if needed. Do not use this medicine to treat a sudden severe asthma attack; use your prescribed rescue inhaler instead and seek emergency help if breathing does not improve.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of this medicine, especially cardiac effects and Theophylline toxicity. Lower doses and close monitoring are recommended. They should also be checked for drug interactions due to multiple medications.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established, and alternative treatments may be considered.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate. Your doctor may adjust the dose before surgery.

🦷 Dental Procedures

Tell your dentist that you are taking this medicine. It can cause dry mouth or tremor, which may affect dental procedures. No major interactions are expected, but maintaining good oral hygiene is important.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Maintain a healthy weight to reduce breathing effort.
😴
Practice breathing exercises as advised by your doctor.
💧
Keep your home free from dust and allergens.
🧘
Get adequate rest and sleep.
🌞
Stay hydrated by drinking plenty of water.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but avoid strenuous activity if you have severe breathlessness. Use your rescue inhaler before exercise if prescribed. Stop and rest if you feel dizzy, chest pain, or severe shortness of breath.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine intake.
Avoid heavy, high-fat meals close to dosing time.
Include potassium-rich foods like bananas and oranges if advised.

💼 Impact on Daily Work & Life

This medicine may cause tremor or dizziness in some people, which can affect driving or operating machinery. Avoid these activities until you know how the medicine affects you. It should not interfere with most desk jobs, but discuss with your doctor if your work involves heavy physical exertion.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition improves, your doctor may adjust or stop the medicine gradually. Sudden discontinuation can worsen asthma or COPD symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine requires regular monitoring of heart rate, blood pressure, and Theophylline blood levels. Prolonged high doses of Theophylline can lead to chronic insomnia, irritability, and rarely, heart or nervous system problems. Periodic review by a doctor is necessary to ensure the dose remains safe and effective.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled Salbutamol or other bronchodilators can provide targeted relief with fewer systemic side effects.

Evidence: Well-established
Inhaled corticosteroids

Used as controller therapy to reduce airway inflammation in asthma.

Evidence: Well-established
Pulmonary rehabilitation

Exercise and education program that improves breathing and quality of life in COPD.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Patients with chronic respiratory diseases should stay up to date with influenza and pneumococcal vaccinations as advised by their doctor. This medicine does not interact with vaccines, but vaccination helps prevent respiratory infections that can worsen asthma or COPD.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the dosing schedule. Store it away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with chronic asthma
He was prescribed this medicine as part of his asthma maintenance plan. He initially experienced mild hand tremor, which reduced after a week. Taking the tablet after breakfast and dinner helped him remember his doses and reduced stomach discomfort. His wheezing episodes became less frequent over a month.
💡 Lesson: Taking the medicine with food and at the same time each day improves tolerability and adherence.
👤 A 65-year-old woman with COPD
She started this medicine along with an inhaled bronchodilator. Her doctor monitored her heart rate and Theophylline levels. She was advised to avoid alcohol and caffeine. She reported better breathing during daily walks, but had to adjust the dose after her kidney function changed.
💡 Lesson: Regular monitoring and dose adjustment are essential, especially in older adults with other health conditions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Salbutamol starts working within 15-30 minutes, while Theophylline takes about 30-60 minutes. The full effect may take a few days of regular use.

Q: Can I take it with my other asthma medicines?

A: Only if your doctor approves. Some combinations can increase side effects, so always inform your doctor about all medicines you take.

Q: Is it safe to take during pregnancy?

A: Consult your doctor. The benefits and risks must be weighed for your specific situation.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nova ventiphylline forte tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for sudden asthma attacks.
    Fact: This medicine is for maintenance therapy and is not a rescue medicine for acute attacks. Use a fast-acting inhaler for sudden symptoms.
  • Myth: It is safe to take extra doses if breathing is difficult.
    Fact: Taking extra doses can cause serious heart and nervous system side effects. Always follow the prescribed dose.
  • Myth: Once symptoms improve, the medicine can be stopped.
    Fact: Stopping suddenly can worsen symptoms. Always consult your doctor before making changes.

🔄 Alternative Options

Generic Alternatives

  • Salbutamol 4 mg + Theophylline 200 mg tablet

Brand Alternatives

  • Nova Ventiphylline Forte Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Salbutamol alone","difference":"Provides rapid bronchodilation but shorter duration; no Theophylline effects."},{"medicine":"Theophylline alone","difference":"Slower onset but longer duration; no beta-2 agonist effects."},{"medicine":"Inhaled Salbutamol","difference":"Faster onset and fewer systemic side effects; used as rescue therapy."}]

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