What is bronkasma tablet used for?

This medicine is a combination of salbutamol and theophylline used to treat asthma and COPD. It works by relaxing the muscles around the airways to make breathing easier. It is taken orally, usually 2-3 times a day, and must be used under medical supervision.

Generic Name: Salbutamol + Theophylline
Manufacturer: Bevit Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 bronkasma tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सल्ब्यूटामोल और थियोफिलिन का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी में सांस लेने में कठिनाई, घरघराहट और छाती में जकड़न को कम करने के लिए किया जाता है। यह वायुमार्ग की मांसपेशियों को आराम देकर सांस लेना आसान बनाती है। इसे मुँह से लिया जाता है और डॉक्टर की सलाह के अनुसार ही लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में हाथों का कंपन, घबराहट, सिरदर्द, धड़कन तेज होना और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, छाती में दर्द, चक्कर आना और पोटैशियम का स्तर कम होना शामिल है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। शराब का सेवन न करें क्योंकि इससे पेट की जलन और दिल की धड़कन बढ़ सकती है। अगर आपको दिल की बीमारी, उच्च रक्तचाप, थायरॉइड, मधुमेह या लीवर की समस्या है तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के कोई अन्य दवा शुरू या बंद न करें। नियमित जांच कराते रहें।

💊 bronkasma tablet Uses & Benefits

[{"condition":"Asthma","description":"Used as maintenance therapy to prevent wheezing and breathlessness in patients with persistent asthma.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps relieve bronchospasm and improve airflow in patients with COPD.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Provides bronchodilation and may reduce exacerbations in chronic bronchitis with reversible airway obstruction.","evidence":"Moderate"},{"condition":"Emphysema","description":"May improve symptoms and exercise tolerance in selected patients with emphysema and bronchospasm.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Bronchiolitis obliterans","description":"Occasionally used in specialized settings for bronchiolitis obliterans after lung transplant, but evidence is limited.","evidence":"Limited"},{"condition":"Apnea of prematurity","description":"Theophylline has been used off-label in premature infants for apnea, but this combination is not standard for that use.","evidence":"Limited"}]

Primary treatment for: Asthma

Also treats: Chronic obstructive pulmonary disease (COPD), Chronic bronchitis, Emphysema

📋 Drug Information

Generic Name(s)	Salbutamol + Theophylline
Brand Name	Asthelite
Manufacturer	Bevit Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	RESPIRATORY
Action Class	Bronchodilator (Beta-2 agonist + Xanthine derivative)
Route of Administration	Oral
Storage	Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container.
Shelf Life	24 months from the date of manufacture.
WHO Guideline	Not established from the available information.
ICMR Guideline	Not established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1

Take this medicine with food to reduce stomach upset.

2

Do not crush or chew the tablet; swallow it whole with water.

3

Avoid caffeine and alcohol while taking this medicine.

4

Monitor your heart rate and report any palpitations or irregular heartbeat.

5

Keep a diary of your symptoms to help your doctor adjust the dose.

6

Do not use this medicine as a rescue inhaler for sudden severe attacks.

7

Inform your doctor about all other medicines you are taking.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Wheezing

This medicine is commonly prescribed for wheezing due to asthma or COPD.

Likely Use

✅

Shortness of breath

Helps improve breathing in obstructive airway diseases.

Likely Use

❌

Fever

This medicine is not a primary fever reducer.

Not Primary

✅

Chest tightness

Bronchodilation helps relieve chest tightness.

Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalbutamol is rapidly absorbed from the gastrointestinal tract after oral administration. Theophylline is also well absorbed orally, but absorption can be affected by food and formulation. This combination tablet is immediate-release, so both ingredients are absorbed relatively quickly.

DistributionSalbutamol distributes widely into body tissues, including the lungs. Theophylline distributes into extracellular fluid and tissues, with a volume of distribution of approximately 0.5 L/kg in adults. Both agents cross the placenta and are excreted in breast milk.

Protein BindingSalbutamol is approximately 10% bound to plasma proteins. Theophylline is about 40% bound to plasma proteins in adults.

MetabolismSalbutamol undergoes extensive first-pass metabolism in the liver, mainly by sulfation. Theophylline is metabolized in the liver by cytochrome P450 enzymes, including CYP1A2 and CYP3A4. Metabolism of theophylline can be affected by many drugs and liver function.

Half-LifeThe elimination half-life of salbutamol is approximately 4 to 6 hours. Theophylline has a variable half-life, typically 3 to 8 hours in healthy adults, but it can be longer in liver disease, heart failure, and in the elderly.

ExcretionSalbutamol and its metabolites are excreted primarily in the urine. Theophylline is excreted partly unchanged in the urine, but most is metabolized before excretion.

BioavailabilityOral salbutamol has a bioavailability of approximately 40% due to first-pass metabolism. Theophylline oral bioavailability is high, generally around 90% to 100% for immediate-release formulations.

Onset of ActionSalbutamol begins to act within 5 to 15 minutes after oral administration. Theophylline has a slower onset, typically 30 to 60 minutes.

Peak Plasma TimePeak plasma concentrations for salbutamol are reached in about 2 to 4 hours. For theophylline, peak levels occur in about 1 to 2 hours for immediate-release formulations.

Duration of ActionSalbutamol's bronchodilator effect lasts about 4 to 6 hours. Theophylline provides bronchodilation for 6 to 12 hours, depending on the dose and individual metabolism.

How It Works

This medicine combines two bronchodilators with different mechanisms. Salbutamol is a short-acting beta-2 adrenergic agonist that stimulates beta-2 receptors on airway smooth muscle, causing relaxation and rapid bronchodilation. Theophylline, a methylxanthine derivative, inhibits phosphodiesterase enzymes, increases cyclic AMP, and blocks adenosine receptors, leading to sustained smooth muscle relaxation and mild anti-inflammatory effects. Together they reduce airway resistance and improve ventilation.

Mechanism Steps

1

Salbutamol binds beta-2 receptors: Salbutamol selectively stimulates beta-2 adrenergic receptors on airway smooth muscle cells.

2

Increased cyclic AMP: Beta-2 receptor activation increases intracellular cyclic AMP, which relaxes smooth muscle.

3

Theophylline inhibits phosphodiesterase: Theophylline blocks phosphodiesterase enzymes, preventing the breakdown of cyclic AMP and prolonging bronchodilation.

4

Adenosine receptor blockade: Theophylline blocks adenosine receptors, reducing bronchoconstriction and mast cell mediator release.

5

Combined bronchodilation: The additive effects of both ingredients lead to significant airway relaxation and improved breathing.

💡 How to Take bronkasma tablet

Strength: Tablet containing salbutamol 4 mg and theophylline 200 mg.

1Take the tablet by mouth with a glass of water.

2Swallow the tablet whole; do not crush or chew.

3Take with food to reduce stomach upset.

4Take at the same times each day to maintain stable levels.

5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult Dosage	The usual adult dose is one tablet taken orally two to three times daily, or as directed by your doctor. The exact dose depends on the indication, severity of symptoms, and individual response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly Dosage	Elderly patients may be more sensitive to the effects of this medicine, especially theophylline. Start with a lower dose and monitor closely for side effects. Dose must be individualized by a qualified clinician.
Renal Impairment	Use with caution in patients with renal impairment. Theophylline and its metabolites are excreted by the kidneys, so dose adjustment may be necessary. Consult your doctor for individualized dosing.
Hepatic Impairment	Use with caution in patients with hepatic impairment. Theophylline metabolism may be reduced, increasing the risk of toxicity. Dose reduction and close monitoring are advised. Consult your doctor for individualized dosing.
Maximum Daily Dose	The maximum daily dose should not exceed the prescribed amount. Typically, theophylline doses above 600 mg per day require monitoring of serum levels. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset and helps maintain consistent absorption.

Caffeine

Limit

Can increase nervousness, tremor, and palpitations.

Charcoal-grilled meats

Avoid excessive intake

May reduce theophylline levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Take the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of bronkasma tablet

✅ Common Side Effects

Tremor (Common (5-10%))

Usually reduces with continued use. If bothersome, consult your doctor.

Nervousness (Common (5-10%))

Try relaxation techniques. Report if it interferes with daily activities.

Headache (Common (5-10%))

Stay hydrated and rest. Consult doctor if persistent.

Palpitations (Common (5-10%))

Avoid caffeine. If palpitations are frequent or severe, seek medical advice.

Nausea (Common (5-10%))

Take with food to reduce stomach upset.

🚨 Serious Side Effects

Cardiac arrhythmias (Uncommon (0.1-1%))

Seek immediate medical attention if you experience irregular heartbeat, chest pain, or fainting.

Severe hypokalemia (Rare (<0.1%))

Report muscle weakness, cramps, or palpitations to your doctor immediately.

Seizures (Rare (<0.1%))

This is a medical emergency. Call for emergency help if seizures occur.

Anaphylaxis (Rare (<0.1%))

Seek emergency care for swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Hyperglycemia

Monitor blood sugar if diabetic. Report persistent high readings.

Hypotension

Report dizziness or fainting to your doctor.

Rash

Discontinue and consult doctor if rash develops.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Ciprofloxacin	Major
Propranolol	Major
Erythromycin	Major
Furosemide	Moderate
Corticosteroids	Moderate
Phenytoin	Moderate
Caffeine	Minor
Ophthalmic beta-blockers	Minor

🚨 Major Interactions

Ciprofloxacin
Propranolol
Erythromycin

⚡ Moderate Interactions

Furosemide
Corticosteroids
Phenytoin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of stomach irritation, worsen palpitations, and may affect theophylline metabolism. It can also add to central nervous system effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to salbutamol, theophylline, or any component of the formulation","Severe cardiac disease, including uncontrolled arrhythmias","Active peptic ulcer disease","Hyperthyroidism (relative contraindication)","Seizure disorders (relative contraindication)"]

⚠️ Warnings & Precautions

["Theophylline has a narrow therapeutic index; dose must be individualized.","Use with caution in patients with heart disease, hypertension, or arrhythmias.","Monitor potassium levels, especially in patients on diuretics or corticosteroids.","Avoid in patients with active peptic ulcer.","Use with caution in the elderly and in patients with liver or kidney disease.","Do not exceed the prescribed dose."]

🤱 Lactation Safety

Salbutamol and theophylline are excreted in breast milk. Theophylline can cause irritability or insomnia in breastfed infants. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose can cause severe nausea, vomiting, tremors, palpitations, seizures, and cardiac arrhythmias. Seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, monitoring of vital signs, and management of seizures and arrhythmias. There is no specific antidote for salbutamol; theophylline overdose may require charcoal hemoperfusion in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not crush or chew the tablet unless your doctor approves. Avoid drinking alcohol because it can increase the risk of stomach irritation and heart rhythm problems. Tell your doctor if you have heart disease, high blood pressure, thyroid problems, diabetes, or liver disease. Do not start or stop any other medicine without consulting your doctor, especially antibiotics, antifungals, or medicines for heart conditions. Keep regular follow-up appointments so your doctor can monitor your heart rate, blood levels of theophylline, and lung function. If you experience palpitations, severe headache, or vomiting, seek medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to theophylline and salbutamol effects. Start with lower doses and monitor closely for cardiac and neurological side effects. Regular follow-up is essential.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before continuing this medicine. Your doctor will weigh the benefits and risks and may adjust or change the treatment.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents and affect heart rate. Your doctor may advise temporary discontinuation or dose adjustment.

🦷 Dental Procedures

Inform your dentist about this medicine. It can cause dry mouth and may interact with certain local anesthetics containing epinephrine. Your dentist may take precautions.

💚 Lifestyle Tips for Better Results

🏃

Avoid smoking and exposure to secondhand smoke.

🥗

Maintain a healthy weight to reduce breathing effort.

😴

Practice breathing exercises as advised by your doctor.

💧

Get adequate rest and sleep.

🧘

Stay hydrated to keep airways moist.

🌞

Use a humidifier if the air is dry.

🏋️ Exercise Considerations

Exercise may trigger bronchospasm in some patients. Use your rescue inhaler if prescribed before exercise. Avoid strenuous activity in cold or polluted air. Consult your doctor before starting a new exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.

Limit caffeine intake.

Avoid excessive charcoal-grilled meats.

Stay well hydrated.

Include foods rich in potassium if advised.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor, which can affect driving or operating machinery. Avoid these activities until you know how the medicine affects you. It should not interfere with most desk jobs, but discuss with your doctor if your work involves heavy machinery.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Abrupt discontinuation may lead to worsening of asthma or COPD symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine requires regular monitoring of theophylline levels, heart rate, and potassium levels. High doses over a long period can lead to chronic insomnia, tremors, and cardiac issues. Your doctor may adjust the dose or add other medicines as needed. Do not stop suddenly without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled salbutamol or other bronchodilators may be preferred for rapid relief and fewer systemic side effects.

Evidence: Well-established

Inhaled corticosteroids

Used as controller therapy for asthma to reduce inflammation.

Evidence: Well-established

Pulmonary rehabilitation

Exercise and education program for COPD patients.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Patients with chronic respiratory diseases should receive annual influenza and pneumococcal vaccinations as advised by their doctor. This medicine does not interact with vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Store away from direct sunlight and moisture.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with chronic asthma

He was prescribed this medicine for maintenance therapy. After taking it regularly with food, his wheezing episodes decreased significantly. He learned to avoid caffeine and reported mild hand tremors initially, which reduced over time.

💡 Lesson: Consistent use with food and avoiding caffeine helps improve tolerability and effectiveness.

👤 A 65-year-old woman with COPD

She started this medicine and noticed improved breathing within a week. However, she experienced palpitations and informed her doctor, who adjusted the dose. She now monitors her heart rate regularly.

💡 Lesson: Elderly patients may need dose adjustment and close monitoring for cardiac side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Salbutamol starts working within 5-15 minutes, while theophylline takes about 30-60 minutes. Full effects may take a few days of regular use.

Q: Can I take it with other asthma medicines?

A: Only if prescribed by your doctor. Some combinations may increase side effects or reduce efficacy.

Q: Is it safe during pregnancy?

A: Consult your doctor. Both ingredients have been used in pregnancy, but risks and benefits must be assessed individually.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my heart?
Can I drive after taking this medicine?
Does it interact with my blood pressure medicine?
What if I miss a dose?
Can I drink alcohol while taking this?

🔄 Substitutes for bronkasma tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: This medicine can be used as a rescue inhaler for sudden attacks.
Fact: This is an oral maintenance medicine and is not suitable for immediate relief of acute severe attacks. A fast-acting inhaler is needed for rescue.
Myth: More is better for breathing problems.
Fact: Taking more than the prescribed dose can cause serious heart and nervous system side effects. Always follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

Salbutamol 4 mg + Theophylline 200 mg tablet

Brand Alternatives

Bronkasma Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Salbutamol alone","difference":"Provides rapid bronchodilation but shorter duration; no anti-inflammatory effect."},{"medicine":"Theophylline alone","difference":"Provides longer bronchodilation but slower onset; narrow therapeutic index."},{"medicine":"This combination","difference":"Combines rapid and sustained bronchodilation for maintenance therapy."}]

Bronkasma Tablet: Complete Medicine Guide

When to Call Your Doctor IMMEDIATELY

What is bronkasma tablet used for?

🇮🇳 bronkasma tablet के बारे में (Hindi Summary)

💊 bronkasma tablet Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take bronkasma tablet

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of bronkasma tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for bronkasma tablet

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

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