Nobel Spas 40 Mg/100 Mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is nimif d 40mg/100mg tablet used for?
This medicine is a combination of Drotaverine and Nimesulide used for short-term relief of painful muscle spasms. It works by relaxing smooth muscles and reducing pain and inflammation.
- Generic Name: Drotaverine (40mg) + Nimesulide (100mg)
- Manufacturer: Caudex Lifecare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimif d 40mg/100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ड्रोटावेरिन और नाइमेसुलाइड का संयोजन है, जिसका उपयोग मांसपेशियों की ऐंठन, पेट दर्द, पित्ताशय की ऐंठन, गुर्दे की पथरी के दर्द और मासिक धर्म की ऐंठन में राहत के लिए किया जाता है। यह दर्द और सूजन को कम करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द और दस्त शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, यकृत की क्षति और गुर्दे की समस्या हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको अल्सर, यकृत या गुर्दे की बीमारी है, तो डॉक्टर को बताएं। बिना सलाह के लंबे समय तक इसका उपयोग न करें।
💊 nimif d 40mg/100mg tablet Uses & Benefits
[{"condition":"Gastrointestinal spasms","description":"Relieves painful spasms of the stomach and intestines.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Helps relieve pain from gallbladder spasms.","evidence":"Well-established"},{"condition":"Renal colic","description":"Used for pain relief in kidney stones and urinary tract spasms.","evidence":"Well-established"},{"condition":"Gynecological spasms","description":"Used for menstrual cramps and other pelvic spasms.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Musculoskeletal pain","description":"Sometimes used for muscle spasms in other conditions.","evidence":"Limited"}]
Primary treatment for: Painful muscle spasms
Also treats: Gastrointestinal spasms, Biliary colic, Renal colic, Gynecological spasms
📋 Drug Information
| Generic Name(s) | Drotaverine (40mg) + Nimesulide (100mg) |
| Brand Name | nimif d 40mg/100mg tablet |
| Manufacturer | Caudex Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Drotaverine inhibits phosphodiesterase 4 (PDE4), increasing cyclic adenosine monophosphate (cAMP) and causing smooth muscle relaxation. Nimesulide is a selective cyclooxygenase-2 (COX-2) inhibitor that reduces prostaglandin synthesis, leading to analgesic and anti-inflammatory effects.
Mechanism Steps
💡 How to Take nimif d 40mg/100mg tablet
Strength: Tablet containing Drotaverine 40 mg and Nimesulide 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet two to three times daily, or as directed by your doctor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and adjust dose as advised by a clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Avoid in patients with severe liver impairment. Use with caution in mild to moderate impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is 3 tablets (120 mg drotaverine and 300 mg nimesulide). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimif d 40mg/100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Lithium | Major | |
| Diuretics | Moderate | |
| ACE inhibitors | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Lithium
⚡ Moderate Interactions
- Diuretics
- ACE inhibitors
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine as it may increase the risk of gastrointestinal bleeding and liver damage.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to drotaverine or nimesulide","Active peptic ulcer or history of recurrent ulcers","Severe liver impairment","Severe kidney impairment","Pregnancy (especially third trimester)","Breastfeeding","Children below 12 years"]
⚠️ Warnings & Precautions
["Take with food to reduce gastrointestinal irritation.","Avoid alcohol.","Do not use for prolonged periods without medical supervision.","Use with caution in elderly patients.","Inform your doctor if you have a history of ulcers, liver or kidney disease, or bleeding disorders."]
🤱 Lactation Safety
Not recommended. Nimesulide may pass into breast milk and could harm the infant. Consult your doctor for alternatives.
💊 Overdose Management
Seek immediate medical attention. Symptoms of overdose may include severe abdominal pain, vomiting, drowsiness, and gastrointestinal bleeding. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food to reduce stomach upset. Avoid alcohol while taking this medicine. Inform your doctor if you have a history of ulcers, liver or kidney disease, or bleeding disorders. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal, liver, and kidney side effects. Use with caution and lower doses may be required. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for safer alternatives.
🏥 Post-Surgery Considerations
Use with caution after surgery due to increased risk of bleeding and kidney impairment. Consult your surgeon before taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while experiencing muscle spasms. Gentle stretching and low-impact activities may help, but consult your doctor before starting any exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery if you experience these effects. It is advisable to rest until you know how the medicine affects you.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or liver problems. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, liver damage, and kidney impairment. Regular monitoring of liver and kidney function is advised if prolonged use is necessary. It is not recommended for chronic use without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve muscle spasms and improve flexibility.
Evidence: Well-establishedApplying heat to the affected area can relax muscles.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after oral administration.
A: It is best taken with food to reduce the risk of stomach upset.
A: Consult your doctor before combining with other painkillers, especially NSAIDs, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for nimif d 40mg/100mg tablet
View AllAlternative brands with exact same active ingredient:
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ospas 40mg/100mg tabletAuspi Medicaments ₹26.25 34.9% CHEAPER
-
dotrasulide 40mg/100mg tabletOyster Labs Ltd ₹28.13 30.2% CHEAPER
-
drotanim 40mg/100mg capsuleShiwalic Formulations Pvt Ltd ₹33.00 18.1% CHEAPER
-
inlid spas 40mg/100mg tabletDonnel Healthcare Pvt Ltd ₹35.63 11.6% CHEAPER
-
mielid spas 40mg/100mg tabletMits Healthcare Pvt Ltd ₹51.56 27.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: It is intended for short-term use only. Prolonged use may increase the risk of side effects. - Myth: It is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Drotaverine + Nimesulide combination generics
Brand Alternatives
- Nobel Spas 40 mg/100 mg Tablet