Eurovil 22.75mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swallowing
- Swelling of the face, lips, tongue, or throat
- Severe dizziness or fainting
- Rapid or irregular heartbeat
- Confusion or hallucinations
- Inability to urinate
- Yellowing of the skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is nicophen 22.75mg injection used for?
This medicine is a pheniramine injection used for rapid relief of severe allergic reactions. It works by blocking histamine H1 receptors and is given by a healthcare professional.
- Generic Name: Pheniramine (22.75mg)
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nicophen 22.75mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा फेनिरामाइन इंजेक्शन है, जिसका उपयोग गंभीर एलर्जी प्रतिक्रियाओं जैसे पित्ती, एंजियोएडेमा, और एलर्जिक राइनाइटिस के त्वरित उपचार के लिए किया जाता है। यह केवल एक योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि और थकान शामिल हैं। गंभीर दुष्प्रभावों में बहुत कम रक्तचाप, तेज़ धड़कन, भ्रम, और पेशाब रोकना शामिल हो सकते हैं।
सुरक्षा सलाह: यह दवा केवल डॉक्टर द्वारा दी जानी चाहिए। इंजेक्शन लेने के बाद कम से कम 30 मिनट तक निगरानी में रहें। शराब का सेवन न करें और वाहन चलाने से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं।
💊 nicophen 22.75mg injection Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Provides rapid relief from sneezing, runny nose, and itching when oral therapy is not possible.","evidence":"Well-established"},{"condition":"Urticaria","description":"Controls itching and hives in acute severe cases.","evidence":"Well-established"},{"condition":"Angioedema","description":"Used as an adjunct to reduce inflammation" class="semantic-link" title="Medicines for swelling">swelling and itching in allergic angioedema.","evidence":"Well-established"},{"condition":"Anaphylaxis (adjunct)","description":"Used alongside epinephrine to counteract histamine-mediated symptoms; not a substitute for epinephrine.","evidence":"Well-established"},{"condition":"Pre-operative sedation","description":"May be used as a component of premedication to reduce anxiety and allergic reactions.","evidence":"Limited"},{"condition":"Transfusion reactions","description":"Given to prevent or treat mild allergic reactions during blood transfusions.","evidence":"Limited"}]
Off-label uses: [{"condition":"Insomnia","description":"Occasionally used off-label for short-term management of insomnia due to its sedative properties.","evidence":"Limited"},{"condition":"Motion sickness","description":"May be used off-label for prevention of motion sickness, though less commonly than other antihistamines.","evidence":"Limited"}]
Primary treatment for: Allergic reactions
Also treats: Urticaria, Angioedema, Allergic rhinitis, Anaphylaxis (adjunct)
📋 Drug Information
| Generic Name(s) | Pheniramine (22.75mg) |
| Brand Name | nicophen 22.75mg injection |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | H1 Antihistaminics (First Generation) |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store below 25°C, protected from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively blocking histamine H1 receptors on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. By binding to these receptors, it prevents histamine from exerting its effects, thereby reducing allergic symptoms such as vasodilation, increased vascular permeability, itching, and bronchoconstriction. Additionally, because it crosses the blood-brain barrier, it causes central nervous system depression, which accounts for its sedative effects.
Mechanism Steps
💡 How to Take nicophen 22.75mg injection
Strength: Injection: 22.75 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 22.75 mg given by intramuscular or intravenous injection, as directed by a physician. The dose may be repeated every 4 to 6 hours as needed, but the maximum daily dose should not exceed 90 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider dose reduction. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. Consult a healthcare provider for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, dose adjustment may be necessary. Consult a healthcare provider for individualized dosing. |
| Maximum Daily Dose | 90 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nicophen 22.75mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Opioids | Major | |
| Benzodiazepines | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Anticholinergics | Moderate | |
| Cimetidine | Minor | |
| Ritonavir | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol
- Opioids
⚡ Moderate Interactions
- Benzodiazepines
- Tricyclic antidepressants
- Anticholinergic drugs (e.g., atropine)
🍷 Alcohol Interaction
Alcohol should be strictly avoided while receiving this medicine and for at least 24 hours afterward. Combining alcohol with this medicine can lead to severe drowsiness, impaired coordination, and increased risk of accidents. It can also intensify central nervous system depression, making it dangerous to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to pheniramine or any component of the formulation","Narrow-angle glaucoma","Prostatic hypertrophy","Bladder neck obstruction","Acute asthma attack","Severe liver disease","Premature infants and neonates"]
⚠️ Warnings & Precautions
["This medicine may cause marked drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostatic hypertrophy, or urinary retention.","Use with caution in patients with cardiovascular disease, hypertension, or hyperthyroidism.","Use with caution in elderly patients due to increased risk of confusion and falls.","Not recommended for children under 2 years of age.","May impair mental and physical abilities required for performing hazardous tasks."]
🤱 Lactation Safety
Pheniramine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, coma, seizures, respiratory depression, and anticholinergic effects. Treatment is supportive and symptomatic. There is no specific antidote. If overdose is suspected, seek emergency medical attention immediately. Gastric lavage may be considered if ingestion was recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
Since this medicine is usually given as a single dose or as needed under medical supervision, a missed dose is unlikely. If you miss a scheduled dose, contact your healthcare provider for guidance. Do not double the dose to catch up.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional. Do not attempt to self-administer. After receiving this injection, remain under medical supervision for at least 30 minutes to monitor for any adverse reactions. Avoid alcohol and other central nervous system depressants for at least 24 hours after receiving this medicine, as they can increase drowsiness and impair your ability to think clearly. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also tell your doctor about all other medicines you are taking, especially sedatives, opioids, and antidepressants, as interactions may occur. Keep all follow-up appointments and report any unusual symptoms immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Use with caution and consider dose reduction. Monitor for confusion, falls, and urinary retention.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before receiving this medicine. It is classified as Pregnancy Category C, and its use should be avoided unless clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used as a pre-operative medication. After surgery, it may contribute to sedation and should be used with caution. Inform your surgeon if you have received this medicine recently.
🦷 Dental Procedures
Inform your dentist if you have received this medicine, as it may interact with sedatives or anesthetics used during dental procedures. It can also cause dry mouth, which may affect dental health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities requiring mental alertness until the sedative effects of this medicine have worn off. Dizziness and drowsiness may increase the risk of injury.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause significant drowsiness and impair your ability to drive or operate machinery. It is advisable to arrange for transportation after receiving the injection and to avoid work that requires alertness for at least 24 hours.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek medical attention immediately. Your doctor will determine if and when to discontinue treatment based on your condition and response.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects such as sedation, anticholinergic effects, and cognitive impairment. Regular monitoring by a healthcare provider is advised if long-term therapy is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For milder allergic reactions, oral antihistamines may be sufficient.
Evidence: Well-establishedIdentifying and avoiding allergens can reduce the need for medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, consult your doctor about any adjustments to your dosing schedule. Keep it in your carry-on luggage if flying, and be prepared to present documentation at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 15 to 30 minutes after injection.
A: The effects usually last for 4 to 6 hours, but drowsiness may persist longer.
A: No, you should avoid driving or operating machinery until you know how this medicine affects you, as it can cause significant drowsiness.
A: It is classified as Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
A: This medicine is excreted in breast milk. Consult your doctor before breastfeeding.
🤔 Common Patient Concerns
🔄 Substitutes for nicophen 22.75mg injection
View AllAlternative brands with exact same active ingredient:
-
instavil 22.75mg injectionIntas Pharmaceuticals Ltd ₹3.75 73.6% COSTLIER
-
eurovil 22.75mg injectionEuro Biogenics ₹5.63 160.6% COSTLIER
-
avil injectionSanofi India Ltd ₹5.86 171.3% COSTLIER
-
kayphen 22.75mg injectionKaytross Health Care ₹17.00 687% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine must be given by a healthcare professional in a medical setting. - Myth: This medicine is safe to use with alcohol.
Fact: Alcohol increases the sedative effects and should be avoided. - Myth: This medicine can replace epinephrine in anaphylaxis.
Fact: This medicine is an adjunct and does not replace epinephrine.
🔄 Alternative Options
Generic Alternatives
- Pheniramine injection
Brand Alternatives
- Eurovil 22.75mg injection