nicardia 5 capsule - Nifedipine (5mg) medicine

Depicor 5mg Tablet (nifedipine): Complete Medicine Guide

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🏭 J B Chemicals and Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 31, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Oct 31, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Chest pain that worsens or does not go away
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Irregular or very fast heartbeat
  • Yellowing of skin or eyes
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is nicardia 5 capsule used for?

This medicine contains nifedipine 5 mg, a calcium channel blocker used to treat high blood pressure and angina. It works by relaxing blood vessels. Take it exactly as prescribed, and avoid grapefruit juice.

  • Generic Name: Nifedipine (5mg)
  • Manufacturer: J B Chemicals and Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nicardia 5 capsule के बारे में (Hindi Summary)

उपयोग: यह दवा निफेडिपिन 5 मिलीग्राम की टैबलेट है, जिसका उपयोग उच्च रक्तचाप (हाई ब्लड प्रेशर) और एनजाइना (सीने में दर्द) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर चौड़ा करती है, जिससे रक्तचाप कम होता है और हृदय को रक्त की आपूर्ति बेहतर होती है। यह दवा रेनॉड्स फेनोमेनन और समय से पहले प्रसव को रोकने के लिए भी कभी-कभी उपयोग की जाती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चेहरे पर गर्मी लगना, चक्कर आना और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी धड़कन तेज होना, जी मिचलाना या कब्ज हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको बेहोशी, तेज धड़कन या चेहरे, होंठ या गले में सूजन हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को चबाएं या तोड़ें नहीं। अंगूर का जूस पीने से बचें, क्योंकि इससे दवा का स्तर बढ़ सकता है। बैठने या लेटने से उठते समय धीरे-धीरे उठें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। नियमित रूप से रक्तचाप की जांच कराएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 nicardia 5 capsule Uses & Benefits

[{"condition":"Hypertension","description":"Lowers blood pressure by relaxing blood vessels, reducing the risk of stroke and heart attack.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Relieves chest pain by improving blood flow to the heart and reducing its workload.","evidence":"Well-established"},{"condition":"Raynaud's phenomenon","description":"Helps reduce frequency and severity of attacks by improving circulation to fingers and toes.","evidence":"Moderate"},{"condition":"Preterm labor","description":"Used to relax uterine muscles and delay premature birth, under specialist supervision.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Anal fissure","description":"Topical nifedipine may help heal anal fissures by relaxing smooth muscle.","evidence":"Limited"},{"condition":"High-altitude pulmonary edema","description":"May be used to prevent or treat this condition in some settings.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Raynaud's phenomenon

📋 Drug Information

Generic Name(s)Nifedipine (5mg)
Brand Namenicardia 5 capsule
ManufacturerJ B Chemicals and Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Avoid grapefruit juice and grapefruit-containing products while on this medicine.
3
Monitor your blood pressure regularly and keep a log to share with your doctor.
4
Rise slowly from sitting or lying positions to prevent dizziness.
5
Do not stop this medicine abruptly without consulting your doctor.
6
Report any swelling of ankles, shortness of breath, or unusual weight gain.
7
Inform your doctor if you experience persistent headaches or flushing.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps relieve angina.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration.
DistributionIt is highly protein-bound and distributes widely in the body, crossing the placenta and appearing in breast milk.
Protein BindingApproximately 92-98% bound to plasma proteins.
MetabolismIt is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4.
Half-LifeThe elimination half-life is approximately 2 to 5 hours.
ExcretionMetabolites are excreted mainly in the urine, with a small amount in feces.
BioavailabilityThe oral bioavailability is about 40-70% due to first-pass metabolism.
Onset of ActionThe onset of action is within 20 to 30 minutes after oral administration.
Peak Plasma TimePeak plasma concentration is reached in about 30 to 60 minutes.
Duration of ActionThe duration of action is approximately 4 to 8 hours.

How It Works

This medicine blocks calcium channels in the smooth muscle cells of blood vessels. By inhibiting calcium influx, it causes relaxation and widening of arteries, leading to reduced peripheral resistance and lower blood pressure. It also dilates coronary arteries, improving oxygen supply to the heart muscle.

Mechanism Steps

1
Calcium channel blockade: This medicine binds to L-type calcium channels on vascular smooth muscle cells.
2
Reduced calcium influx: This prevents calcium from entering the cells, leading to relaxation.
3
Vasodilation: Blood vessels widen, reducing peripheral resistance and blood pressure.
4
Improved blood flow: Coronary arteries dilate, increasing oxygen supply to the heart and relieving angina.

💡 How to Take nicardia 5 capsule

Strength: Nifedipine 5 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it at the same times each day.
4You may take it with or without food, but be consistent.
5Avoid grapefruit juice.

Dosage Information

Adult DosageThe usual starting dose for hypertension is 5 mg three times daily, but your doctor may adjust based on response. For angina, the dose may be 5-10 mg three times daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects. Start with a lower dose and monitor closely.
Renal ImpairmentNo specific dose adjustment is usually required, but use with caution in severe renal impairment.
Hepatic ImpairmentDose reduction may be necessary in patients with liver impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 mg for immediate-release tablets, but this may vary based on indication and patient factors.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nicardia 5 capsule

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Flushing (Common (5-10%))
May subside with continued use. Avoid alcohol.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position.
Peripheral edema (Common (5-10%))
Elevate legs and consult doctor if severe.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you feel faint or have very low blood pressure.
Worsening angina (Rare (<0.1%))
Contact doctor immediately if chest pain increases.
Allergic reactions (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Gum hyperplasia
Maintain good oral hygiene and consult dentist.
Hepatotoxicity
Report yellowing of eyes or skin to doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Beta-blockers Major
Grapefruit juice Major
Digoxin Moderate
Cimetidine Moderate
Antacids Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • Beta-blockers
  • Grapefruit juice

⚡ Moderate Interactions

  • Digoxin
  • Cimetidine

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect and increase dizziness. Avoid or limit alcohol consumption.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to nifedipine","Cardiogenic shock","Severe aortic stenosis","Unstable angina (unless under specialist care)","Within 4 weeks of myocardial infarction"]

⚠️ Warnings & Precautions

["May cause dizziness; avoid driving until you know how it affects you.","Avoid grapefruit juice.","Use with caution in elderly and those with liver or kidney disease.","Do not stop abruptly without medical advice.","Inform your doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

Nifedipine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor.

💊 Overdose Management

Overdose may cause severe hypotension, tachycardia, and loss of consciousness. Seek immediate medical attention. Treatment is supportive and may include activated charcoal, intravenous fluids, and vasopressors.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed. Do not crush or chew the tablet unless your doctor advises otherwise. Avoid drinking grapefruit juice while taking this medicine, as it can increase the drug levels in your body. Stand up slowly from a sitting or lying position to prevent dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments and monitor your blood pressure regularly. Store this medicine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to blood pressure lowering effects. Start with a lower dose and monitor closely for dizziness and falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine is generally considered safe in pregnancy but requires monitoring.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine. It may need to be temporarily stopped before surgery.

🦷 Dental Procedures

Inform your dentist about this medicine. It may cause gum swelling, so maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Reduce salt intake in your diet.
😴
Engage in regular physical activity like walking or swimming.
💧
Manage stress through relaxation techniques.
🧘
Get adequate sleep.
🌞
Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise initially as it may cause dizziness. Stay hydrated and rise slowly after exercise.

🥗 Diet Recommendations

Follow a low-sodium diet.
Include potassium-rich foods like bananas and oranges.
Avoid grapefruit and grapefruit juice.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

May cause dizziness or drowsiness initially. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use is generally safe when monitored. Regular check-ups for blood pressure, heart rate, and liver function are advised. Some patients may develop gum swelling or ankle edema. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage blood pressure.

Evidence: Well-established
Other antihypertensives

ACE inhibitors, ARBs, or diuretics may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines. Continue routine vaccinations as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about dose timing. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure
Started this medicine as prescribed. Initially experienced mild headache and flushing, which subsided after a week. Blood pressure improved significantly. He learned to avoid grapefruit juice and take the medicine at the same time daily.
💡 Lesson: Consistency and avoiding grapefruit juice are key to safe and effective treatment.
👤 A 62-year-old woman with angina
Was prescribed this medicine for chest pain. She noticed fewer angina attacks within two weeks. She was advised to rise slowly due to dizziness. She now monitors her blood pressure regularly.
💡 Lesson: Regular monitoring and slow position changes help manage side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 20-30 minutes, but full effects on blood pressure may take a few days.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause a dangerous rise.

Q: What should I avoid while taking this medicine?

A: Avoid grapefruit juice and alcohol. Be cautious when driving until you know how it affects you.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nicardia 5 capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine can cause a dangerous rise in blood pressure. Continue as prescribed.
  • Myth: This medicine damages the kidneys.
    Fact: This medicine is used to protect kidneys from damage caused by high blood pressure. It does not damage kidneys when used appropriately.

🔄 Alternative Options

Generic Alternatives

  • Nifedipine 5 mg immediate-release tablet

Brand Alternatives

  • Depicor 5mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Nifedipine immediate-release","class":"Calcium channel blocker","onset":"20-30 minutes","duration":"4-8 hours","common_uses":"Hypertension, angina"},{"medicine":"Amlodipine","class":"Calcium channel blocker","onset":"6-12 hours","duration":"24 hours","common_uses":"Hypertension, angina"}]

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