cardules 5mg capsule - Nifedipine (5mg) medicine

Angiblock 5mg Capsule: Complete Medicine Guide

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🏭 Abbott 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 1, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High for hypertension and angina; moderate for Raynaud's phenomenon.
Reviewed by
SaathiMed Expert Panel | Nov 01, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Chest pain that is new or worsening
  • Swelling of face, lips, tongue, or throat
  • Irregular or very fast heartbeat
  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is cardules 5mg capsule used for?

This medicine is a calcium channel blocker used to treat high blood pressure and angina. It works by relaxing blood vessels, making it easier for the heart to pump blood. It is available as a 5mg immediate-release capsule and is taken orally, usually three times a day. Common side effects include headache, flushing, and dizziness. It should not be used in patients with cardiogenic shock or severe aortic stenosis.

  • Generic Name: Nifedipine
  • Manufacturer: Abbott
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cardules 5mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर रक्त के प्रवाह को आसान बनाती है, जिससे रक्तचाप कम होता है और हृदय पर दबाव कम पड़ता है। यह दवा तुरंत प्रभाव के लिए बनाई गई है और इसे दिन में तीन बार तक लिया जा सकता है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर गर्मी लगना, चक्कर आना और टखनों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में बहुत कम रक्तचाप, दिल की धड़कन तेज होना, और एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, इसे पूरा निगल लें। इस दवा के साथ अंगूर का जूस न पिएं क्योंकि इससे दवा का असर बढ़ सकता है और दुष्प्रभाव हो सकते हैं। डॉक्टर की सलाह के बिना दवा लेना अचानक बंद न करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cardules 5mg capsule Uses & Benefits

[{"condition":"Hypertension","description":"This medicine helps lower high blood pressure by relaxing blood vessels, reducing the risk of strokes and heart attacks.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"It reduces the frequency and severity of chest pain by improving blood flow to the heart.","evidence":"Well-established"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"This medicine is effective in preventing coronary artery spasms that cause chest pain at rest.","evidence":"Well-established"},{"condition":"Raynaud's phenomenon","description":"It can help reduce the frequency and severity of attacks in some patients.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Preterm labor (tocolytic)","description":"Sometimes used to delay premature labor, but not first-line.","evidence":"Limited"},{"condition":"Anal fissure","description":"Topical nifedipine may be used to relieve pain and promote healing.","evidence":"Moderate"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Raynaud's phenomenon

📋 Drug Information

Generic Name(s)Nifedipine
Brand NameAngiblock 5mg Capsule
ManufacturerAbbott
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same times each day to maintain consistent blood levels.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Avoid grapefruit juice and grapefruit-containing products while on this medicine.
4
Rise slowly from a sitting or lying position to prevent dizziness due to low blood pressure.
5
Do not stop this medicine abruptly; your doctor will taper the dose if needed.
6
Report any swelling of ankles, shortness of breath, or rapid heartbeat to your doctor.
7
Limit alcohol intake as it can enhance the blood pressure-lowering effect.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for hypertension.
Likely Use
✅
Chest pain (angina)
This medicine helps prevent angina attacks.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not used for headache relief; it may cause headache as a side effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. However, it undergoes extensive first-pass metabolism in the liver, resulting in a bioavailability of about 40-70%.
DistributionThis medicine is highly bound to plasma proteins (approximately 92-98%) and is widely distributed in the body. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 92-98% bound to plasma proteins, primarily albumin and lipoproteins.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4, into inactive metabolites.
Half-LifeThe elimination half-life of this medicine is approximately 2 to 5 hours in healthy adults. In patients with liver cirrhosis, the half-life may be prolonged.
ExcretionThis medicine is primarily excreted in the urine as inactive metabolites, with a small amount excreted in the feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 40-70% due to first-pass metabolism.
Onset of ActionThe onset of action for this medicine is within 20-30 minutes after oral administration for immediate-release capsules.
Peak Plasma TimePeak plasma concentrations are reached within 30 minutes to 2 hours after oral administration.
Duration of ActionThe duration of action of this medicine is approximately 4 to 8 hours for immediate-release formulations.

How It Works

This medicine works by blocking calcium channels in the smooth muscle cells of blood vessels and the heart. By inhibiting the influx of calcium ions, it causes relaxation and widening of blood vessels (vasodilation), which lowers blood pressure and improves blood flow to the heart. This also reduces the workload on the heart and helps relieve angina.

Mechanism Steps

1
Calcium channel blockade: This medicine binds to L-type calcium channels on the surface of smooth muscle cells and cardiac muscle cells.
2
Inhibition of calcium influx: By blocking these channels, it prevents calcium ions from entering the cells during depolarization.
3
Smooth muscle relaxation: Reduced intracellular calcium leads to relaxation of vascular smooth muscle, causing vasodilation.
4
Decreased peripheral resistance: Vasodilation lowers systemic vascular resistance, which reduces blood pressure and afterload.
5
Improved coronary blood flow: Dilation of coronary arteries increases oxygen delivery to the heart muscle, relieving angina.

💡 How to Take cardules 5mg capsule

Strength: Nifedipine 5mg immediate-release capsule

1Swallow the capsule whole with a glass of water.
2Do not crush, chew, or break the capsule.
3Take it at the same times each day, with or without food.
4Avoid grapefruit juice while taking this medicine.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual starting dose of this medicine for hypertension is 10 mg three times a day. For angina, the dose may be 10-20 mg three times a day. Your doctor may adjust the dose based on your response and tolerance. The maximum recommended dose is 120 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is required for renal impairment, but use with caution. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with liver impairment, the dose of this medicine should be reduced and titrated slowly. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 120 mg for immediate-release formulations. However, doses above 90 mg are rarely used. Dose must be individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Grapefruit
Avoid
May increase drug levels and risk of side effects.
High-fat meals
Take consistently
May delay absorption but not clinically significant.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cardules 5mg capsule

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if it persists or is severe.
Flushing (Common (5-10%))
This is a temporary effect. If bothersome, talk to your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate your legs when sitting. Consult your doctor if swelling is severe or persistent.
Nausea (Common (1-5%))
Take with food to reduce stomach upset.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or rapid heartbeat.
Worsening angina or heart attack (Rare (<0.1%))
Get emergency help if you have new or worsening chest pain.
Allergic reactions (Rare (<0.1%))
Seek immediate medical attention if you notice rash, itching, swelling of face/lips/tongue, or difficulty breathing.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

⚠️ Rare Side Effects

Gynecomastia
Consult your doctor if you notice breast enlargement or tenderness.
Mood changes
Talk to your doctor if you experience depression or anxiety.
Thrombocytopenia
Report unusual bruising or bleeding to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Grapefruit juice Major
Metoprolol Major
Cimetidine Moderate
Rifampicin Moderate
Digoxin Moderate
Antacids Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir)
  • Grapefruit juice
  • Beta-blockers (e.g., metoprolol, atenolol)
  • Alpha-blockers (e.g., prazosin)

⚡ Moderate Interactions

  • Cimetidine
  • Rifampicin
  • Digoxin

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, or increased heart rate. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to nifedipine","Cardiogenic shock","Severe aortic stenosis","Unstable angina (immediate-release form)","Within 4 weeks of myocardial infarction"]

⚠️ Warnings & Precautions

["May cause severe hypotension; monitor blood pressure closely.","Use with caution in patients with heart failure.","May worsen angina at the start of therapy.","Avoid abrupt withdrawal; taper dose gradually.","Use with caution in patients with liver impairment.","May cause dizziness; avoid driving until you know how it affects you."]

🤱 Lactation Safety

This medicine is excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.

💊 Overdose Management

Overdose of this medicine can cause severe hypotension, tachycardia, and loss of consciousness. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Gastric lavage may be considered if taken recently. Administer intravenous fluids and vasopressors if needed to maintain blood pressure.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a glass of water. Avoid drinking grapefruit juice while taking this medicine, as it can increase the amount of medicine in your blood and cause side effects. Do not stop taking this medicine suddenly without consulting your doctor, as this can worsen your condition. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, tell your doctor about all other medicines you are taking, especially blood pressure medicines, antibiotics, and antifungal drugs. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor closely for dizziness and falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine is Category C and may not be the first choice during pregnancy. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect blood pressure during surgery. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it can cause gum hyperplasia and may interact with certain dental anesthetics. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Limit salt intake to help control blood pressure.
💧
Practice stress-reduction techniques such as deep breathing or meditation.
🧘
Get adequate sleep to support heart health.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

This medicine may cause dizziness or lightheadedness, especially when you first start taking it. Avoid strenuous exercise or heavy lifting until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Include potassium-rich foods like bananas and oranges.
Reduce sodium intake.
Avoid grapefruit and grapefruit juice.
Eat a balanced diet rich in fruits, vegetables, and whole grains.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your daily activities, but take precautions when rising from sitting or lying positions.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your condition improves, your doctor may gradually reduce the dose. Abrupt withdrawal can worsen your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance and reduced effectiveness in some patients. Regular monitoring of blood pressure, heart rate, and liver function is recommended. It may also cause gum hyperplasia (gum overgrowth) in rare cases. Periodic review with your doctor is essential to adjust the dose and assess the need for continued therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage hypertension and angina.

Evidence: Well-established
Other antihypertensive medications

ACE inhibitors, ARBs, diuretics, or beta-blockers may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually under your doctor&#039;s guidance. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of high blood pressure
He was prescribed this medicine 5mg three times a day. After a week, his blood pressure improved, but he experienced mild headaches and flushing. His doctor advised him to continue and the side effects gradually subsided. He now monitors his blood pressure daily and feels more energetic.
💡 Lesson: Common side effects like headache and flushing often diminish with continued use. Regular monitoring helps track progress.
👤 A 62-year-old woman with angina
She started this medicine for chest pain and noticed fewer episodes within two weeks. She learned to avoid grapefruit juice after her doctor warned her about interactions. She also started walking daily, which improved her overall heart health.
💡 Lesson: Combining medicine with lifestyle changes like exercise and dietary adjustments can significantly improve outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 20-30 minutes after oral administration, with peak effects in about 1-2 hours.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset. Avoid grapefruit juice.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to stop this medicine suddenly?

A: No, stopping suddenly can cause a rebound increase in blood pressure or angina. Always consult your doctor before stopping.

Q: Can I take this medicine during pregnancy?

A: This medicine is Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cardules 5mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken only when you have chest pain.
    Fact: This medicine is used regularly to prevent angina and control blood pressure, not just for acute attacks.
  • Myth: You can stop taking this medicine once your blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine can cause a dangerous rise in blood pressure. Always consult your doctor before stopping.
  • Myth: This medicine is safe to take with grapefruit juice.
    Fact: Grapefruit juice can increase the levels of this medicine in your body, leading to serious side effects. Avoid it.

🔄 Alternative Options

Generic Alternatives

  • Nifedipine 5mg immediate-release capsule

Brand Alternatives

  • Angiblock 5mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Nifedipine","class":"Calcium channel blocker","half_life":"2-5 hours","common_side_effects":"Headache, flushing, edema"},{"medicine":"Amlodipine","class":"Calcium channel blocker","half_life":"30-50 hours","common_side_effects":"Edema, dizziness, flushing"},{"medicine":"Felodipine","class":"Calcium channel blocker","half_life":"11-16 hours","common_side_effects":"Headache, flushing, edema"}]

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