nam cold tablet sr - Nimesulide (100mg) + Loratadine (5mg) medicine

Nam Cold Tablet Sr: Complete Medicine Guide

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🏭 Lincoln Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Nimesulide is not recommended during pregnancy, especially in the third trimester, due to risks to the fetus. Loratadine is generally considered safe in pregnancy but consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is nam cold tablet sr used for?

This medicine is a combination of nimesulide (an NSAID) and loratadine (an antihistamine) used for short-term relief of allergic symptoms with pain and inflammation. It should be taken orally with food, usually once or twice daily, as prescribed by a doctor. It is not recommended for children under 12, pregnant women in the third trimester, or people with severe liver or kidney disease.

  • Generic Name: Nimesulide (100mg) + Loratadine (5mg)
  • Manufacturer: Lincoln Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nam cold tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा नाइमेसुलाइड और लोराटाडीन का संयोजन है, जिसका उपयोग एलर्जी के लक्षणों जैसे छींक, नाक बहना, आंखों में खुजली और पानी आना, तथा साथ में दर्द और सूजन के इलाज के लिए किया जाता है। यह दवा सर्दी-जुकाम के साथ एलर्जी होने पर भी राहत देती है। इसे डॉक्टर की सलाह के अनुसार ही लें और खाने के बाद लें ताकि पेट में जलन न हो।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, नींद आना और मुंह सूखना शामिल हैं। कभी-कभी पेट में अल्सर या खून आना, लिवर की समस्या, किडनी की समस्या, या गंभीर एलर्जी हो सकती है। अगर आपको काला मल, खून की उल्टी, पीलिया, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, खुद से ज्यादा मात्रा में न लें। इसे खाने के बाद पानी के साथ लें। इस दवा के साथ शराब न पिएं। अगर आपको पेट की बीमारी, किडनी, लिवर, या दिल की बीमारी है, तो डॉक्टर को बताएं। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना इसका इस्तेमाल न करें। बच्चों को 12 साल से कम उम्र में यह दवा न दें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 nam cold tablet sr Uses & Benefits

[{"condition":"Allergic rhinitis","description":"This medicine helps relieve sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Moderate"},{"condition":"Common cold with allergic symptoms","description":"It provides symptomatic relief from fever, body ache, and allergic symptoms such as sneezing and watery eyes during a cold.","evidence":"Limited"},{"condition":"Mild to moderate pain with allergic features","description":"The nimesulide component helps reduce pain and inflammation, while loratadine addresses associated allergic symptoms.","evidence":"Limited"},{"condition":"Urticaria (hives) with pain","description":"Loratadine controls itching and rash, while nimesulide may help with any accompanying pain or inflammation.","evidence":"Limited"}]

Off-label uses: [{"condition":"Post-operative pain with allergic component","description":"Sometimes prescribed off-label for short-term pain relief after surgery when allergic symptoms are also present.","evidence":"Limited"},{"condition":"Dental pain with allergic rhinitis","description":"May be used off-label for dental pain in patients who also have allergic symptoms.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis with pain and inflammation

Also treats: Common cold with allergic symptoms, Urticaria with pain, Mild to moderate pain with allergic features

📋 Drug Information

Generic Name(s)Nimesulide (100mg) + Loratadine (5mg)
Brand Namenam cold tablet sr
ManufacturerLincoln Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not drive or operate machinery if you feel drowsy.
8
Inform your doctor about all other medicines you are taking.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
✅
Itchy and watery eyes
Loratadine helps relieve allergic eye symptoms.
Likely Use
✅
Fever with body ache
Nimesulide helps reduce fever and pain.
Likely Use
❌
Chest pain
This medicine is not for chest pain; seek immediate medical attention.
Not Primary
❌
Severe abdominal pain
This medicine is not for severe abdominal pain; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNimesulide is rapidly absorbed from the gastrointestinal tract after oral administration. Loratadine is also well absorbed orally. Food may slightly delay the absorption of loratadine but does not significantly affect the extent of absorption.
DistributionNimesulide is highly bound to plasma proteins and distributes well into tissues, including synovial fluid. Loratadine is widely distributed and does not readily cross the blood-brain barrier at therapeutic doses.
Protein BindingNimesulide is approximately 99% bound to plasma proteins. Loratadine is approximately 97-99% bound to plasma proteins.
MetabolismNimesulide is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2C9. Loratadine is metabolized in the liver to descarboethoxyloratadine, an active metabolite, mainly via CYP3A4 and CYP2D6.
Half-LifeThe elimination half-life of nimesulide is approximately 2-5 hours. The elimination half-life of loratadine is approximately 8-14 hours, and its active metabolite has a longer half-life of about 17-24 hours.
ExcretionNimesulide and its metabolites are primarily excreted in urine and feces. Loratadine and its metabolites are excreted mainly in urine and feces.
BioavailabilityNimesulide has an oral bioavailability of approximately 80-90%. Loratadine has an oral bioavailability of approximately 40-60% due to first-pass metabolism.
Onset of ActionNimesulide typically begins to relieve pain and fever within 30-60 minutes after oral administration. Loratadine starts reducing allergic symptoms within 1-3 hours.
Peak Plasma TimeNimesulide reaches peak plasma concentration in about 1.5-3 hours. Loratadine reaches peak plasma concentration in about 1-2 hours.
Duration of ActionThe analgesic and anti-inflammatory effects of nimesulide last about 6-8 hours. The anti-allergic effects of loratadine last about 24 hours.

How It Works

This medicine combines two active ingredients with different mechanisms. Nimesulide is a non-steroidal anti-inflammatory drug that selectively inhibits the cyclo-oxygenase-2 (COX-2) enzyme, which reduces the production of prostaglandins that cause pain, inflammation, and fever. Loratadine is a second-generation antihistamine that selectively blocks peripheral histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, runny nose, and watery eyes. The combination provides both anti-inflammatory and anti-allergic effects.

Mechanism Steps

1
COX-2 inhibition by nimesulide: Nimesulide selectively binds to and inhibits the COX-2 enzyme, reducing the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Lower prostaglandin levels lead to decreased pain, inflammation, and fever.
3
Histamine H1 receptor blockade by loratadine: Loratadine competes with histamine for binding at peripheral H1 receptors, preventing histamine-mediated allergic responses.
4
Reduced allergic symptoms: Blockade of H1 receptors decreases sneezing, itching, runny nose, and watery eyes.

💡 How to Take nam cold tablet sr

Strength: Immediate-release tablet containing nimesulide 100 mg and loratadine 5 mg.

1Take the tablet orally with a full glass of water.
2Take it after a meal to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not take more than the prescribed dose.
5Follow your doctor's instructions regarding duration of treatment.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, preferably after food, as prescribed by your doctor. The exact dose and duration depend on the condition being treated, your age, weight, kidney and liver function, and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney problems, and liver injury. Use with caution and at the lowest effective dose. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction or avoidance may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction or avoidance may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is one tablet twice daily, but this must be confirmed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and gastrointestinal irritation.
Grapefruit
Avoid
May increase drug levels by affecting metabolism.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver problems.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nam cold tablet sr

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Stomach pain (Common (5-10%))
Take after meals. If pain is severe or persistent, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe.
Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Dry mouth (Common (5-10%))
Drink plenty of water. Chew sugar-free gum if needed.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Liver injury (Rare (<0.1%))
Stop the medicine and seek immediate medical help if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical care immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or unexplained weight gain to your doctor promptly.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in the mouth.
Blood disorders (agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, fever, and sensitivity to light.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ibuprofen Major
Corticosteroids Major
ACE inhibitors Major
Diuretics Major
Lithium Moderate
Methotrexate Moderate
Fluconazole Moderate
Ketoconazole Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, diclofenac)
  • Corticosteroids
  • ACE inhibitors and angiotensin receptor blockers (ARBs)
  • Diuretics

⚡ Moderate Interactions

  • Lithium
  • Methotrexate
  • CYP2C9 inhibitors (e.g., fluconazole)
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulcers, and liver damage, especially when combined with nimesulide. It may also increase drowsiness caused by loratadine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to nimesulide, loratadine, or any other NSAID","Active or history of peptic ulcer or gastrointestinal bleeding","Severe liver disease","Severe kidney disease","Severe heart failure","Third trimester of pregnancy","Breastfeeding","Children below 12 years of age","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs"]

⚠️ Warnings & Precautions

["Use the lowest effective dose for the shortest duration possible.","Take with food to reduce gastrointestinal irritation.","Avoid alcohol while taking this medicine.","Do not use concurrently with other NSAIDs.","Use with caution in elderly patients due to increased risk of side effects.","Monitor liver and kidney function during prolonged use.","Stop the medicine and consult a doctor if you experience signs of liver injury, bleeding, or allergic reaction.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not drive or operate machinery if you feel drowsy.","Keep out of reach of children."]

🤱 Lactation Safety

Nimesulide is not recommended during breastfeeding as it may pass into breast milk and harm the infant. Loratadine is considered safe during breastfeeding but consult your doctor before use.

💊 Overdose Management

Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, drowsiness, and potentially liver or kidney damage. If you suspect an overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and symptomatic, with monitoring of vital signs, liver and kidney function, and electrolyte levels. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, and do not exceed the recommended dose or duration. Swallow the tablet whole with a glass of water, preferably after food, to reduce the chance of stomach upset. Avoid drinking alcohol while taking this medicine because it can increase the risk of gastrointestinal bleeding and liver problems. Do not take other pain relievers, fever reducers, or anti-inflammatory medicines without consulting your doctor, as this may increase the risk of side effects. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before starting this medicine. Do not use this medicine for more than the recommended number of days unless your doctor advises otherwise. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this product. Keep this medicine out of the reach of children and store it in a cool, dry place away from direct sunlight. If you experience any signs of an allergic reaction, such as rash, swelling, or difficulty breathing, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and liver injury from this medicine. Use with caution, at the lowest effective dose, and for the shortest duration. Regular monitoring of kidney and liver function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Nimesulide is not recommended during pregnancy, especially in the third trimester, due to risks to the fetus. Alternative treatments may be safer.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your doctor. It may increase the risk of bleeding and interfere with wound healing. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and improve overall health.
🥗
Regular low-impact exercise like walking or swimming can help reduce pain and improve mobility.
😴
Practice good posture to prevent musculoskeletal strain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich foods in your diet.
🧘
Get adequate sleep to support your immune system and recovery.
🌞
Stay well hydrated throughout the day.
🚭
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

While taking this medicine, you may feel drowsy or dizzy. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you experience muscle pain or weakness, consult your doctor before continuing exercise.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated by drinking plenty of water.
Avoid alcohol and caffeine in excess.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some people, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. It is advisable to take it after food and rest if needed. Inform your employer if your work requires alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as stomach bleeding, liver problems, or allergic reactions. Do not stop or change the dose without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, liver injury, kidney problems, and cardiovascular events. It should only be used for short-term relief unless otherwise directed by a doctor. Regular monitoring of liver and kidney function may be required if prolonged use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps relieve nasal congestion and allergic symptoms without medication.

Evidence: Well-established
Antihistamine alone (e.g., loratadine)

May be sufficient for allergic symptoms without pain or inflammation.

Evidence: Well-established
Paracetamol for pain and fever

Safer alternative for pain and fever, especially if NSAIDs are not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, continue taking your doses as prescribed, but consult your doctor if you need to adjust the timing. Keep enough supply for your entire trip. Check local customs regulations regarding carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis and mild body ache
She was prescribed this medicine for her allergic symptoms and body pain. She took it after breakfast as advised. Within a few days, her sneezing and runny nose improved significantly, and her body ache reduced. She experienced mild drowsiness initially but it subsided after a few days.
💡 Lesson: Taking the medicine with food and following the prescribed dose helps achieve good symptom relief with minimal side effects.
👤 A 50-year-old man with a common cold and allergic symptoms
He started this medicine on his doctor's advice. He noticed relief from fever and sneezing within a day. However, he developed mild stomach pain, which improved when he took it after meals. He was advised not to take it for more than 5 days.
💡 Lesson: Taking this medicine after food reduces gastrointestinal side effects, and it should not be used for prolonged periods without medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain and fever within 30-60 minutes, and allergic symptoms within 1-3 hours.

Q: Can I take this medicine on an empty stomach?

A: It is best to take this medicine after food to reduce the risk of stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I take this medicine with other pain relievers?

A: Do not take other NSAIDs or pain relievers without consulting your doctor, as it may increase the risk of side effects.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children below 12 years of age. Consult a pediatrician for appropriate treatment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other cold medicines?

🔄 Substitutes for nam cold tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of pain.
    Fact: This medicine is specifically for allergic symptoms with pain and inflammation. It is not suitable for all types of pain and should only be used as prescribed.
  • Myth: It is safe to take this medicine for a long time.
    Fact: Long-term use of this medicine can increase the risk of liver, kidney, and gastrointestinal problems. It should be used for the shortest duration possible.
  • Myth: This medicine is safe for children.
    Fact: This medicine is not recommended for children below 12 years of age due to safety concerns.

🔄 Alternative Options

Generic Alternatives

  • Nimesulide 100 mg + Loratadine 5 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Nimesulide + Loratadine","composition":"Nimesulide 100 mg + Loratadine 5 mg","uses":"Allergic symptoms with pain and inflammation","notes":"Combination product"},{"medicine":"Nimesulide alone","composition":"Nimesulide 100 mg","uses":"Pain, inflammation, fever","notes":"No antihistamine effect"},{"medicine":"Loratadine alone","composition":"Loratadine 10 mg","uses":"Allergic rhinitis, urticaria","notes":"No anti-inflammatory effect"}]

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