myset r 4mg/150mg tablet - Ondansetron (4mg) + Ranitidine (150mg) medicine

Acidom O 4 mg/150 mg Tablet: Complete Medicine Guide

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🏭 Captab Biotec 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or stool
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Irregular heartbeat or palpitations
  • Swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is myset r 4mg/150mg tablet used for?

This medicine is a combination of Ondansetron (4 mg) and Ranitidine (150 mg) used to treat nausea, vomiting, and acid-related stomach problems. It works by blocking nausea signals and reducing stomach acid.

  • Generic Name: Ondansetron (4mg) + Ranitidine (150mg)
  • Manufacturer: Captab Biotec
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 myset r 4mg/150mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ओंडानसेट्रॉन 4 मिलीग्राम और रैनिटिडीन 150 मिलीग्राम का संयोजन है। इसका उपयोग मतली, उल्टी और पेट की अम्लता से जुड़ी समस्याओं के इलाज के लिए किया जाता है। यह मतली और उल्टी को रोकने में मदद करती है और पेट में एसिड का स्तर कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, कब्ज, दस्त, थकान, चक्कर आना और पेट में परेशानी शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, एलर्जी, और सेरोटोनिन सिंड्रोम शामिल हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। अन्य दवाओं के बारे में डॉक्टर को बताएं। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। चक्कर आने पर वाहन न चलाएं। ठंडी और सूखी जगह पर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 myset r 4mg/150mg tablet Uses & Benefits

[{"condition":"Nausea and vomiting with acid-related disorders","description":"Used to control nausea and vomiting in patients who also have conditions like GERD or gastritis where acid suppression is beneficial.","evidence":"Moderate"},{"condition":"Chemotherapy-induced nausea and vomiting (CINV) with acid suppression","description":"Ondansetron prevents CINV, while Ranitidine reduces stomach acid that may exacerbate nausea.","evidence":"Moderate"},{"condition":"Postoperative nausea and vomiting (PONV) with acid reduction","description":"May be used post-surgery to manage nausea and prevent acid-related discomfort.","evidence":"Limited"}]

Off-label uses: [{"condition":"Hyperemesis gravidarum","description":"Ondansetron is sometimes used off-label for severe morning sickness, but Ranitidine is not typically recommended in pregnancy without medical advice.","evidence":"Limited"}]

Primary treatment for: Nausea and vomiting with acid-related disorders

Also treats: Gastroesophageal reflux disease (GERD), Gastritis, Chemotherapy-induced nausea and vomiting

📋 Drug Information

Generic Name(s)Ondansetron (4mg) + Ranitidine (150mg)
Brand Namemyset r 4mg/150mg tablet
ManufacturerCaptab Biotec
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Do not exceed the prescribed dose.
3
Avoid alcohol while taking this medicine.
4
Inform your doctor if you have heart rhythm problems.
5
Report any unusual bleeding or bruising immediately.
6
Consult your doctor if symptoms persist beyond 7 days.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nausea and vomiting
This medicine is commonly prescribed for this.
Likely Use
✅
Heartburn
Ranitidine component helps reduce acid.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOndansetron is well absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations reached in about 1.5 to 2 hours. Ranitidine is also rapidly absorbed, with peak levels in 1 to 3 hours. Food does not significantly affect the absorption of either component.
DistributionBoth drugs are distributed widely throughout the body. Ondansetron has a volume of distribution of about 140 L, while Ranitidine has a volume of distribution of about 1.4 L/kg. Ondansetron crosses the blood-brain barrier; Ranitidine crosses the placenta and is excreted in breast milk.
Protein BindingOndansetron is approximately 70-76% bound to plasma proteins. Ranitidine is about 15% bound to plasma proteins.
MetabolismOndansetron is extensively metabolized in the liver by cytochrome P450 enzymes, including CYP3A4, CYP2D6, and CYP1A2. Ranitidine undergoes hepatic metabolism to a lesser extent, with about 30-40% metabolized in the liver.
Half-LifeOndansetron: 3-6 hours; Ranitidine: 2-3 hours.
ExcretionOndansetron is excreted in urine and feces as metabolites and unchanged drug. Ranitidine is primarily excreted unchanged in urine (about 70%) and feces (about 30%).
BioavailabilityOndansetron oral bioavailability is about 60%. Ranitidine oral bioavailability is about 50%.
Onset of ActionOndansetron: within 30-60 minutes; Ranitidine: within 1 hour.
Peak Plasma TimeOndansetron: 1.5-2 hours; Ranitidine: 1-3 hours.
Duration of ActionOndansetron: 4-8 hours; Ranitidine: 8-12 hours.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Ondansetron selectively blocks serotonin 5-HT3 receptors in the gastrointestinal tract and central nervous system, preventing nausea and vomiting. Ranitidine competitively inhibits histamine H2 receptors on gastric parietal cells, reducing both basal and stimulated gastric acid secretion.

Mechanism Steps

1
Ondansetron blocks 5-HT3 receptors: Ondansetron binds to 5-HT3 receptors on vagal afferent nerves and in the chemoreceptor trigger zone, blocking serotonin signals that trigger nausea and vomiting.
2
Ranitidine inhibits H2 receptors: Ranitidine competes with histamine for H2 receptors on gastric parietal cells, reducing cyclic AMP production and thus decreasing gastric acid secretion.
3
Combined effect: The combination addresses both nausea/vomiting and excess acid, providing symptomatic relief in conditions where both are problematic.

💡 How to Take myset r 4mg/150mg tablet

Strength: Tablet containing Ondansetron 4 mg and Ranitidine 150 mg.

1Swallow the tablet whole with a glass of water.
2Take with food to reduce stomach upset.
3Do not crush or chew the tablet.
4Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally up to twice daily, or as directed by your doctor. The dose may be adjusted based on your condition, kidney and liver function, and other medications. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment due to reduced kidney and liver function. Consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be needed in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum daily dose should not exceed what is prescribed by your doctor. Typically, ondansetron 8 mg and ranitidine 300 mg per day in divided doses, but individual limits vary.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase drowsiness and stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of myset r 4mg/150mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if severe.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if persistent.
Fatigue (Common (5-10%))
Rest. Avoid driving if drowsy.
Dizziness (Common (5-10%))
Avoid sudden movements. Consult doctor if severe.

🚨 Serious Side Effects

Irregular heartbeat (QT prolongation) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or shortness of breath.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you have rash, itching, swelling, or difficulty breathing.
Serotonin syndrome (Rare (<0.1%))
Seek immediate care if you have agitation, hallucinations, fever, fast heart rate, or muscle stiffness.

⚠️ Rare Side Effects

Blood disorders (e.g., thrombocytopenia)
Report unusual bruising or bleeding to your doctor.
Liver enzyme elevation
Regular monitoring may be needed. Report yellowing of skin or eyes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Apomorphine Major
Amiodarone Major
Tramadol Moderate
Fluoxetine Moderate
Ketoconazole Moderate
Antacids Minor

🚨 Major Interactions

  • Apomorphine
  • QT-prolonging drugs (e.g., amiodarone, sotalol)

⚡ Moderate Interactions

  • Tramadol
  • SSRIs (e.g., fluoxetine)
  • Ketoconazole

🍷 Alcohol Interaction

Alcohol may increase drowsiness, dizziness, and the risk of stomach irritation. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ondansetron or ranitidine","Use with apomorphine","Severe liver impairment without medical supervision","Congenital long QT syndrome"]

⚠️ Warnings & Precautions

["May cause dizziness; avoid driving until you know how it affects you.","Use with caution in patients with heart rhythm disorders.","May mask symptoms of gastric cancer; rule out malignancy before use.","Adjust dose in renal and hepatic impairment.","Avoid in patients with phenylketonuria (some formulations may contain aspartame)."]

🤱 Lactation Safety

Ondansetron and ranitidine are excreted in breast milk. Consult a doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause severe drowsiness, irregular heartbeat, or allergic reactions. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Inform your doctor about all other medications you are taking, especially those for heart rhythm problems, depression, or infections. Avoid alcohol while taking this medicine as it may increase drowsiness and stomach irritation. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects like dizziness and confusion. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy or are pregnant. Ondansetron may be used with caution, but Ranitidine should be used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used post-surgery for nausea and acid control. Inform your surgeon and anesthesiologist about all medicines you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain anesthetics or medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid spicy and fatty foods that can worsen acidity.
🥗
Eat small, frequent meals.
😴
Stay hydrated with water and clear fluids.
💧
Avoid lying down immediately after eating.
🧘
Manage stress through relaxation techniques.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after taking this medicine if you feel dizzy or drowsy. Stay hydrated during exercise.

🥗 Diet Recommendations

Include bland, easy-to-digest foods.
Avoid caffeine and carbonated drinks.
Reduce alcohol intake.
Eat smaller meals more frequently.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to concentrate.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor will advise on tapering or stopping based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may require monitoring of liver and kidney function, and heart rhythm. Ranitidine has been associated with rare blood disorders. Consult your doctor for regular check-ups if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can help reduce acid reflux and nausea.

Evidence: Well-established
Stress management

Yoga and meditation can help reduce stress-related nausea and acidity.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor before any vaccination while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with frequent nausea and acid reflux
She was prescribed this medicine for her symptoms. After taking it as directed with meals, her nausea reduced significantly and her heartburn improved within a few days. She was advised to avoid spicy foods and alcohol.
💡 Lesson: Taking the medicine with food and following lifestyle advice improves outcomes.
👤 A 50-year-old man undergoing chemotherapy
He experienced severe nausea after chemotherapy. His doctor added this medicine to his regimen. It helped control his nausea and reduced stomach discomfort. He was monitored for heart rhythm changes.
💡 Lesson: Combination therapy can be effective for chemotherapy-induced nausea when acid suppression is also needed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Ondansetron starts working within 30-60 minutes, while Ranitidine takes about 1 hour to reduce acid.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe for long-term use?

A: Long-term use should be under medical supervision. Regular monitoring may be needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for myset r 4mg/150mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure all types of stomach pain.
    Fact: It is specifically for nausea, vomiting, and acid-related conditions, not all stomach pain.
  • Myth: It is safe to take without a prescription.
    Fact: It is a prescription medicine and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Ondansetron 4 mg + Ranitidine 150 mg tablet (generic)

📊 Comparison with Similar Medicines

[{"medicine":"Ondansetron alone","difference":"Only treats nausea and vomiting, no acid suppression."},{"medicine":"Ranitidine alone","difference":"Only reduces stomach acid, no anti-nausea effect."}]

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