anset or 4mg/150mg tablet - Ondansetron (4mg) + Ranitidine (150mg) medicine

Anset 4mg/150mg Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Bennet Mypher Pharmaceuticals LLP 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Irregular heartbeat or palpitations
  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Blood in vomit or stool
  • Severe abdominal pain
  • Yellowing of skin or eyes
  • Decreased urine output
  • Confusion or hallucinations
  • Fainting or loss of consciousness

If experiencing severe symptoms, call emergency services immediately.

What is anset or 4mg/150mg tablet used for?

This medicine is a combination of Ondansetron (4 mg) and Ranitidine (150 mg) used to treat nausea, vomiting, and acid-related stomach problems. It works by blocking serotonin signals that cause vomiting and reducing stomach acid production. It is available as an oral tablet and should be taken as prescribed by a doctor.

  • Generic Name: Ondansetron + Ranitidine
  • Manufacturer: Bennet Mypher Pharmaceuticals LLP
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anset or 4mg/150mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ओंडानसेट्रॉन 4 मिलीग्राम और रैनिटिडीन 150 मिलीग्राम का संयोजन है। इसका उपयोग मतली, उल्टी और एसिडिटी से जुड़ी पेट की समस्याओं के इलाज के लिए किया जाता है। ओंडानसेट्रॉन उल्टी को रोकता है और रैनिटिडीन पेट में एसिड बनने को कम करता है। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, कब्ज, दस्त, थकान, चक्कर आना और पेट दर्द शामिल हैं। कुछ लोगों को मुँह सूखना, नींद आना या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, गंभीर एलर्जी, या खून की समस्या हो सकती है। अगर कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। पानी के साथ पूरी गोली निगलें। खाने के साथ या बिना खाने के ले सकते हैं, लेकिन पेट खराब लगे तो खाने के साथ लें। शराब न पिएं। अगर चक्कर या नींद आए तो वाहन न चलाएं। दिल, लिवर, किडनी की बीमारी हो तो डॉक्टर को बताएं। बिना सलाह दवा बंद न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 anset or 4mg/150mg tablet Uses & Benefits

[{"condition":"Nausea and vomiting associated with acid peptic disease","description":"This combination helps control vomiting while reducing gastric acid, providing relief in conditions like gastritis and gastroesophageal reflux disease.","evidence":"Well-established"},{"condition":"Chemotherapy-induced nausea and vomiting (CINV)","description":"Ondansetron is a standard antiemetic for CINV, and ranitidine may be added to reduce acid-related stomach discomfort.","evidence":"Well-established"},{"condition":"Postoperative nausea and vomiting (PONV)","description":"Ondansetron is commonly used to prevent and treat PONV, and ranitidine helps manage acid secretion during recovery.","evidence":"Well-established"},{"condition":"Gastritis with vomiting","description":"Ranitidine reduces acid production, while ondansetron controls nausea and vomiting, offering dual symptom relief.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Hyperemesis gravidarum","description":"Ondansetron is sometimes used off-label for severe nausea and vomiting in pregnancy, but ranitidine is generally avoided in pregnancy unless clearly needed.","evidence":"Limited"},{"condition":"Cyclic vomiting syndrome","description":"Ondansetron may be used off-label to manage episodes of cyclic vomiting, but the combination with ranitidine is not standard.","evidence":"Limited"}]

Primary treatment for: Nausea and vomiting with acid peptic disease

Also treats: Gastroesophageal reflux disease (GERD), Gastritis, Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting

📋 Drug Information

Generic Name(s)Ondansetron + Ranitidine
Brand NameAnset OR 4mg/150mg Tablet
ManufacturerBennet Mypher Pharmaceuticals LLP
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntiemetic + H2 Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed; do not self-adjust the dose.
2
Take it with food if it causes stomach upset.
3
Avoid alcohol while taking this medicine to prevent increased drowsiness and stomach irritation.
4
Do not drive or operate heavy machinery if you feel dizzy or drowsy.
5
Inform your doctor if you have heart, liver, or kidney problems before taking this medicine.
6
Report any unusual symptoms like palpitations, fainting, or severe allergic reactions immediately.
7
Do not take this medicine for longer than recommended without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nausea and vomiting
This medicine is commonly prescribed for this.
Likely Use
✅
Heartburn and acid indigestion
Ranitidine component helps reduce stomach acid.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not intended for headache relief.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOndansetron is well absorbed from the gastrointestinal tract after oral administration, with an absolute bioavailability of about 60%. Ranitidine is rapidly absorbed, with a bioavailability of approximately 50%. Food does not significantly affect the absorption of either component.
DistributionOndansetron is widely distributed in the body, with a volume of distribution of about 140 L. Ranitidine distributes widely to tissues, including breast milk, and has a volume of distribution of about 1.4 L/kg. Both drugs cross the placenta.
Protein BindingOndansetron is approximately 70-76% bound to plasma proteins. Ranitidine is about 15% bound to plasma proteins.
MetabolismOndansetron is extensively metabolized in the liver by cytochrome P450 enzymes, including CYP3A4, CYP2D6, and CYP1A2. Ranitidine undergoes hepatic metabolism to a lesser extent, primarily to N-oxide, S-oxide, and desmethyl metabolites.
Half-LifeThe elimination half-life of ondansetron is approximately 3-6 hours in adults. Ranitidine has an elimination half-life of about 2-3 hours.
ExcretionOndansetron is excreted in urine (about 44%) and feces (about 56%) as metabolites and unchanged drug. Ranitidine is primarily excreted unchanged in urine (about 70%) via active tubular secretion.
BioavailabilityOndansetron oral bioavailability is about 60%. Ranitidine oral bioavailability is approximately 50%.
Onset of ActionOndansetron begins to relieve nausea within 30-60 minutes after oral administration. Ranitidine starts reducing gastric acid within 1 hour.
Peak Plasma TimeOndansetron reaches peak plasma concentration in about 1.5-2 hours. Ranitidine peaks in about 1-3 hours.
Duration of ActionOndansetron's antiemetic effect lasts about 4-8 hours. Ranitidine's acid-suppressive effect lasts up to 8-12 hours.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Ondansetron selectively blocks 5-HT3 receptors in the gastrointestinal tract and the central nervous system, preventing serotonin from triggering the vomiting reflex. Ranitidine competitively blocks histamine H2 receptors on gastric parietal cells, reducing both basal and stimulated gastric acid secretion. Together, they address nausea and vomiting while reducing stomach acid, which can help alleviate associated discomfort.

Mechanism Steps

1
Ondansetron blocks 5-HT3 receptors: Ondansetron binds to 5-HT3 receptors on vagal afferent nerves and in the chemoreceptor trigger zone, preventing serotonin from initiating the vomiting reflex.
2
Ranitidine blocks H2 receptors: Ranitidine competitively inhibits histamine at H2 receptors on gastric parietal cells, reducing cyclic AMP production and subsequent acid secretion.
3
Combined effect: The antiemetic action of ondansetron and the acid-suppressive action of ranitidine work together to relieve nausea, vomiting, and acid-related stomach discomfort.

💡 How to Take anset or 4mg/150mg tablet

Strength: Tablet containing Ondansetron 4 mg and Ranitidine 150 mg.

1Swallow the tablet whole with a glass of water.
2Do not crush, chew, or break the tablet.
3Take it with or without food, but with food if it upsets your stomach.
4Follow the prescribed schedule consistently.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet containing Ondansetron 4 mg and Ranitidine 150 mg taken orally once or twice daily, or as directed by your doctor. The exact dose and frequency depend on the condition being treated, your age, kidney and liver function, and other medications you are taking. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and heart rhythm changes. Dose adjustment may be necessary based on kidney and liver function. Consult your doctor.
Renal ImpairmentRanitidine dose should be reduced in patients with renal impairment. Ondansetron does not require dose adjustment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, the dose of ondansetron should not exceed 8 mg per day. Ranitidine should be used with caution. Consult your doctor for dose adjustment.
Maximum Daily DoseThe maximum daily dose of ondansetron is generally 16 mg (for oral use) and ranitidine is 300 mg. However, the maximum daily dose of this combination should not exceed the prescribed limit. Follow your doctor's advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase drowsiness and stomach irritation.
Caffeine
Moderate intake
May increase nervousness or palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anset or 4mg/150mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if it persists.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if it lasts more than 2 days.
Fatigue (Common (5-10%))
Rest and avoid driving if you feel tired. Consult doctor if it interferes with daily activities.
Dizziness (Common (5-10%))
Avoid sudden movements. Do not drive or operate machinery if dizzy.

🚨 Serious Side Effects

QT prolongation and arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or irregular heartbeat.
Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Call emergency services if you notice swelling of face, lips, throat, or difficulty breathing.
Blood disorders (e.g., thrombocytopenia) (Rare (<0.1%))
Report unusual bruising or bleeding to your doctor immediately.
Liver enzyme elevation (Rare (<0.1%))
Inform your doctor if you notice yellowing of skin or eyes, dark urine, or abdominal pain.

⚠️ Rare Side Effects

Confusion or hallucinations
Contact your doctor if you experience mental status changes, especially if you are elderly or have kidney disease.
Slow heart rate (bradycardia)
Seek medical attention if you feel faint or have a very slow pulse.
Serotonin syndrome
Seek immediate care if you have agitation, hallucinations, fever, sweating, or muscle stiffness, especially if taking other serotonergic drugs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Apomorphine Major
Amiodarone Major
SSRIs Major
Ketoconazole Moderate
Rifampicin Moderate
Warfarin Moderate
Antacids Minor
Ketoconazole (for antifungal use) Minor

🚨 Major Interactions

  • Apomorphine
  • QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
  • Serotonergic drugs (e.g., SSRIs, SNRIs, MAOIs)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)
  • Warfarin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of stomach irritation. It may also worsen nausea and vomiting.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ondansetron, ranitidine, or any component of the formulation","Concurrent use with apomorphine","Congenital long QT syndrome","Severe hepatic impairment (for ranitidine)","Use in patients with phenylketonuria if the formulation contains aspartame (not applicable to tablets)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with heart disease, electrolyte abnormalities, or those taking other QT-prolonging drugs.","Ranitidine dose should be reduced in renal impairment.","Ondansetron may mask symptoms of intestinal obstruction.","Avoid alcohol during treatment.","Do not exceed the recommended dose.","Consult your doctor if symptoms persist or worsen."]

🤱 Lactation Safety

Ondansetron is excreted in breast milk in small amounts; caution is advised. Ranitidine is also excreted in breast milk and may cause side effects in the infant. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, dizziness, fainting, irregular heartbeat, or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor ECG and vital signs.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless instructed. Swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase drowsiness and stomach irritation. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have heart problems, liver disease, kidney disease, or electrolyte imbalances. Do not take this medicine for longer than recommended without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose. If you experience any serious side effects, contact your doctor immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects like confusion, dizziness, and heart rhythm changes. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Ondansetron and ranitidine should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used to prevent postoperative nausea and vomiting. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures. It may also cause dry mouth, which can affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Eat small, frequent meals to reduce acid reflux.
🥗
Avoid spicy, oily, and acidic foods.
😴
Stay hydrated by drinking plenty of water.
💧
Avoid lying down immediately after eating.
🧘
Manage stress through relaxation techniques like deep breathing.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or fatigued. Light activities like walking are generally safe. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Include bland, easy-to-digest foods like bananas, rice, applesauce, and toast.
Avoid caffeine, alcohol, and carbonated drinks.
Reduce intake of spicy and fatty foods.
Eat smaller, more frequent meals.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause fatigue, so plan your work accordingly.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Abrupt discontinuation may cause rebound symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of vitamin B12 deficiency due to ranitidine, and rare blood disorders. Prolonged use should be monitored by a doctor, with periodic blood tests if necessary. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can help manage acid reflux and nausea.

Evidence: Well-established
Stress reduction

Techniques like yoga and meditation may reduce nausea and acid symptoms.

Evidence: Moderate
Acupuncture

May help with nausea and vomiting in some patients.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your doctor about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with severe nausea and vomiting due to gastritis
She was prescribed this medicine twice daily. Within a day, her vomiting stopped and stomach discomfort reduced. She was advised to take it with food and avoid spicy meals. She completed the 5-day course and felt much better.
💡 Lesson: Taking the medicine with food and following dietary advice improves tolerability and effectiveness.
👤 A 60-year-old man receiving chemotherapy experienced nausea and acid reflux
His doctor added this combination to his regimen. It helped control both chemotherapy-induced nausea and acid-related stomach pain. He was monitored for heart rhythm changes due to his age and history of hypertension.
💡 Lesson: Elderly patients and those with heart conditions need careful monitoring while on this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Ondansetron starts relieving nausea within 30-60 minutes, and ranitidine reduces acid within 1 hour.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: Is it safe during pregnancy?

A: Consult your doctor. Ondansetron is used in pregnancy only if clearly needed, and ranitidine should be used with caution.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but skip if it's almost time for the next dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anset or 4mg/150mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure all types of stomach problems.
    Fact: It is specifically for nausea, vomiting, and acid-related conditions. It does not treat infections or other causes of stomach pain.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This is a prescription medicine. Self-medication can be harmful, especially if you have heart, liver, or kidney problems.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: Always complete the prescribed course and consult your doctor before stopping, as abrupt discontinuation may cause rebound symptoms.

🔄 Alternative Options

Generic Alternatives

  • Ondansetron 4 mg + Ranitidine 150 mg tablet (generic)

📊 Comparison with Similar Medicines

[{"medicine":"Ondansetron + Ranitidine","composition":"Ondansetron 4 mg + Ranitidine 150 mg","uses":"Nausea, vomiting, acid peptic disease","notes":"Combination product"},{"medicine":"Ondansetron alone","composition":"Ondansetron 4 mg","uses":"Nausea and vomiting","notes":"No acid suppression"},{"medicine":"Ranitidine alone","composition":"Ranitidine 150 mg","uses":"Acid peptic disease","notes":"No antiemetic effect"}]

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