Abclopid A 75 Capsule: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or stomach cramps
- Sudden severe headache, confusion, or difficulty speaking
- Unexplained bruising or bleeding that does not stop
- Chest pain or difficulty breathing
- Swelling of the face, lips, or throat
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is myogrel ap 75mg/75mg tablet used for?
This medicine is a combination of aspirin and clopidogrel, two antiplatelet drugs used to prevent blood clots in people with heart or blood vessel disease. It is taken once daily by mouth, usually with food, and must be prescribed by a doctor. Do not stop taking it without medical advice.
- Generic Name: Aspirin (75mg) + Clopidogrel (75mg)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 myogrel ap 75mg/75mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एस्पिरिन और क्लोपिडोग्रेल का संयोजन है, जिसका उपयोग रक्त के थक्के बनने से रोकने के लिए किया जाता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें दिल का दौरा, स्ट्रोक या दिल की धमनियों में स्टेंट लगाया गया है। यह दवा रक्त को पतला करके थक्के बनने के खतरे को कम करती है। इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए और बिना पूछे बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में जलन, अपच, मतली, और आसानी से चोट लगने या खून बहने की समस्या शामिल है। कुछ लोगों को सिरदर्द, दस्त या नाक बहना भी हो सकता है। गंभीर दुष्प्रभावों में पेट या दिमाग में खून बहना, और एलर्जी की प्रतिक्रिया शामिल है। अगर आपको काला मल, खून की उल्टी, या अचानक कमजोरी महसूस हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे खाने के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में खून बहने का खतरा बढ़ सकता है। कोई भी सर्जरी या दांत का इलाज कराने से पहले अपने डॉक्टर को बताएं कि आप यह दवा ले रहे हैं। अगर आपको कोई नई दवा शुरू करनी है तो पहले डॉक्टर से सलाह लें। दवा को कमरे के तापमान पर, धूप और नमी से दूर रखें।
💊 myogrel ap 75mg/75mg tablet Uses & Benefits
[{"condition":"Acute coronary syndrome (heart attack or unstable angina)","description":"This medicine is used to prevent further blood clots in patients who have had a heart attack or unstable angina, often along with other treatments.","evidence":"Well-established"},{"condition":"Post-stent placement (after angioplasty)","description":"It helps prevent stent thrombosis, a serious complication where a blood clot forms inside the stent.","evidence":"Well-established"},{"condition":"Ischemic stroke or transient ischemic attack (TIA)","description":"It reduces the risk of recurrent stroke or TIA in patients with a history of these conditions.","evidence":"Well-established"},{"condition":"Peripheral artery disease","description":"It may be prescribed to reduce the risk of cardiovascular events in patients with narrowed arteries in the legs.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prevention of blood clots in certain high-risk patients with atrial fibrillation who cannot take anticoagulants","description":"Sometimes considered off-label, but not standard first-line therapy.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention (secondary prevention after heart attack, stroke, or stent placement)
Also treats: Peripheral artery disease, Transient ischemic attack (TIA), Stable angina
📋 Drug Information
| Generic Name(s) | Aspirin (75mg) + Clopidogrel (75mg) |
| Brand Name | myogrel ap 75mg/75mg tablet |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Do not refrigerate unless specified. Keep in the original container, tightly closed. Keep out of reach of children. |
| Shelf Life | Typically 24 months from the date of manufacture, but check the expiry date on the pack. |
| WHO Guideline | Not established from the available information. Guidelines from various cardiology societies recommend dual antiplatelet therapy with aspirin and a P2Y12 inhibitor like clopidogrel for a certain duration after acute coronary syndrome or stent placement, but the exact duration and indication should be determined by a qualified clinician. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research may have guidelines on antiplatelet therapy, but specific recommendations for this combination should be verified with a doctor. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antiplatelet agents with complementary mechanisms. Aspirin irreversibly inhibits the cyclooxygenase-1 (COX-1) enzyme in platelets, which blocks the production of thromboxane A2, a substance that promotes platelet clumping and blood vessel narrowing. Clopidogrel is a prodrug that is activated in the liver and then irreversibly blocks the P2Y12 ADP receptor on platelets. This prevents ADP from activating the platelet and reduces the activation of the glycoprotein IIb/IIIa complex, which is needed for platelets to stick together. By blocking two different pathways, this medicine provides stronger and more consistent prevention of blood clot formation than either ingredient alone.
Mechanism Steps
💡 How to Take myogrel ap 75mg/75mg tablet
Strength: Capsule containing aspirin 75 mg and clopidogrel 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (containing aspirin 75 mg and clopidogrel 75 mg) taken orally once daily, with or without food. However, the dose and duration of treatment must be individualized by a qualified clinician based on the specific indication, the patient's age, weight, kidney and liver function, and other medications being taken. Some patients may need a loading dose of clopidogrel at the start of treatment, as determined by the doctor. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be at a higher risk of bleeding while taking this medicine. The dose is generally the same as for adults, but careful monitoring for bleeding is recommended. The doctor may adjust the dose based on kidney and liver function. |
| Renal Impairment | No specific dose adjustment is usually needed for mild to moderate kidney impairment. In severe kidney disease, caution is advised, and the doctor may monitor kidney function closely. The dose should be individualized by a clinician. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe liver disease. In mild to moderate liver impairment, caution is advised, and the doctor may adjust the dose or monitor liver function. The dose should be individualized by a clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (aspirin 75 mg + clopidogrel 75 mg) once daily. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of myogrel ap 75mg/75mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Omeprazole | Major | |
| SSRIs | Major | |
| Corticosteroids | Moderate | |
| Methotrexate | Moderate | |
| Fluconazole | Moderate | |
| Carbamazepine | Moderate | |
| Antacids | Minor | |
| Ginkgo biloba | Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- NSAIDs (e.g., ibuprofen, naproxen)
- Omeprazole and esomeprazole
- SSRIs and SNRIs (antidepressants)
⚡ Moderate Interactions
- Corticosteroids
- Methotrexate
- Fluconazole, ketoconazole, voriconazole
- Carbamazepine, phenytoin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the risk of stomach bleeding and may reduce the effectiveness of the medicine. If you drink alcohol, talk to your doctor about safe limits.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding, such as bleeding ulcers or bleeding in the brain","Known allergy to aspirin or clopidogrel","Severe liver disease","Bleeding disorders (e.g., hemophilia)","Recent or upcoming surgery where bleeding risk is high","Children and teenagers with viral infections (risk of Reye's syndrome with aspirin)"]
⚠️ Warnings & Precautions
["This medicine increases the risk of bleeding. Report any unusual bleeding or bruising to your doctor.","Do not stop taking this medicine without consulting your doctor, especially if you have a heart stent.","Inform your doctor if you have a history of stomach ulcers or bleeding.","Avoid alcohol while taking this medicine.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","This medicine may interact with many other drugs. Always inform your doctor about all medicines you are taking.","If you are scheduled for surgery or dental work, tell your doctor or dentist that you are taking this medicine."]
🤱 Lactation Safety
Aspirin and clopidogrel may pass into breast milk. The use of this medicine while breastfeeding is not recommended unless clearly needed and advised by a doctor. Consult your doctor to discuss the risks and benefits.
💊 Overdose Management
Overdose of this medicine can cause severe bleeding, stomach pain, vomiting, and other symptoms. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include stomach lavage, activated charcoal, and supportive care. There is no specific antidote for clopidogrel, but platelet transfusion may be considered in severe bleeding.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop taking it without consulting your doctor, especially if you have a stent in your heart, because stopping suddenly can increase the risk of a heart attack or stent blockage. Take this medicine with food to reduce stomach upset. Avoid alcohol while taking this medicine because it can increase the risk of stomach bleeding. Inform all your healthcare providers, including your dentist, that you are taking this medicine before any surgery or dental procedure. Do not take other pain relievers or blood thinners without checking with your doctor first. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at a higher risk of bleeding while taking this medicine. The dose is generally the same as for younger adults, but careful monitoring for signs of bleeding is recommended. Kidney and liver function should be assessed regularly, and the dose may need adjustment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before stopping or continuing this medicine. The safety of this medicine during pregnancy is not well established, and it may increase the risk of bleeding for both mother and baby. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
This medicine increases the risk of bleeding during and after surgery. Your doctor may advise you to stop taking it several days before a planned surgery. Do not stop it on your own. After surgery, your doctor will decide when it is safe to restart.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure, including tooth extraction. Your dentist may consult with your doctor to decide whether to adjust or temporarily stop the medicine to reduce bleeding risk. Do not stop the medicine without your doctor's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is good for your heart, but because this medicine increases bleeding risk, avoid contact sports or activities with a high risk of injury. Activities like walking, swimming, and cycling are generally safe. If you experience any bleeding or unusual symptoms during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to work or drive. However, if you experience dizziness or unusual bleeding, avoid driving or operating heavy machinery until you feel better. Inform your employer about your condition if your job involves a risk of injury.
🛑 When to Stop This Medicine
Do not stop taking this medicine unless your doctor tells you to. If you experience serious side effects such as severe bleeding, your doctor may advise you to stop. In some cases, the medicine may be stopped after a certain period, such as one year after stent placement, but this decision must be made by your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is often necessary to prevent cardiovascular events. The main risk of long-term use is an increased tendency to bleed, including gastrointestinal bleeding. Regular monitoring for signs of bleeding is important. Your doctor may also monitor your blood counts and kidney function. Do not stop the medicine without medical advice, as the risk of clots may return.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be sufficient for some patients who do not need dual antiplatelet therapy.
Evidence: Well-establishedAn option for patients who cannot take aspirin.
Evidence: Well-establishedAnother dual antiplatelet option, but with different dosing and side effect profile.
Evidence: Well-establishedHeart-healthy diet, exercise, and smoking cessation can complement medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, because this medicine increases bleeding risk, intramuscular injections should be given with caution. Inform your healthcare provider before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or moisture. If you are crossing time zones, continue taking your dose at the same time each day according to your home schedule, or adjust gradually as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect begins within a few hours, but the full protective effect builds up over several days. If you are given a loading dose, the effect is faster.
A: No, you should never stop taking this medicine without consulting your doctor. Stopping suddenly can increase the risk of heart attack, stroke, or stent blockage.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is best to avoid alcohol while taking this medicine because it can increase the risk of stomach bleeding.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for myogrel ap 75mg/75mg tablet
View AllAlternative brands with exact same active ingredient:
-
starclop-a 75mg/75mg capsuleZinnia Life Sciences ₹2.91 83.9% CHEAPER
-
clopiril-as tabletZeelab Pharmacy Pvt Ltd ₹18.00 0.5% CHEAPER
-
davaindia aspirin+clopidogrel 75mg/75mg tabletDavaindia Generic Pharmacy ₹20.00 10.6% COSTLIER
-
carpigrel-a tabletShrrishti Health Care Products Pvt Ltd ₹22.27 23.1% COSTLIER
-
clopid as 75mg/75mg tabletHetero Drugs Ltd ₹23.12 27.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller. It is an antiplatelet medicine used to prevent blood clots. - Myth: I can stop taking this medicine once I feel better.
Fact: You should never stop taking this medicine without consulting your doctor, as stopping suddenly can increase the risk of heart attack or stroke. - Myth: This medicine can be taken with any other medicine.
Fact: This medicine can interact with many other drugs, including painkillers and blood thinners. Always check with your doctor before taking any new medicine. - Myth: This medicine is safe to take during pregnancy.
Fact: The safety of this medicine during pregnancy is not well established. Consult your doctor if you are pregnant or planning to become pregnant.
🔄 Alternative Options
Generic Alternatives
- Aspirin + Clopidogrel combination (generic versions available)
Brand Alternatives
- Clopilet A 75
- Deplatt A 75
- Combiplat 75
- Noklot 75
- Pidogrel A 75