mucospel syrup - Bromhexine (NA) medicine

Bisolvon Syrup (Bromhexine): Comprehensive Medicine Guide

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🏭 S R Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for mucolytic effects in respiratory conditions.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is mucospel syrup used for?

This medicine is a mucolytic syrup containing bromhexine, used to thin and loosen mucus in the airways, making it easier to cough out. It is commonly used for productive coughs associated with bronchitis and other respiratory conditions.

  • Generic Name: Bromhexine (NA)
  • Manufacturer: S R Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 mucospel syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन सिरप है, जो कफ को पतला करने और बलगम को आसानी से बाहर निकालने में मदद करती है। इसका उपयोग ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं में गाढ़े बलगम के कारण होने वाली खांसी के इलाज के लिए किया जाता है। यह दवा बलगम को पतला करके श्वसन मार्ग को साफ करने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असुविधा, सिरदर्द, चक्कर आना और पसीना आना शामिल हो सकते हैं। कभी-कभी एलर्जी प्रतिक्रियाएं जैसे दाने, खुजली या चेहरे, होंठ या गले में सूजन हो सकती है। यदि कोई गंभीर या लगातार दुष्प्रभाव हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। यदि आपको पेप्टिक अल्सर, लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। यदि आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। 14 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें। बच्चों की पहुंच से दूर रखें। ठंडी, सूखी जगह पर स्टोर करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 mucospel syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps to thin and loosen mucus in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Used as a mucolytic to relieve symptoms of acute or chronic bronchitis with excessive mucus.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May be used to help clear mucus in patients with COPD, though it is not a primary treatment.","evidence":"Limited"}]

Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to help thin mucus in sinusitis, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Productive cough

Also treats: Bronchitis, COPD

📋 Drug Information

Generic Name(s)Bromhexine (NA)
Brand Namemucospel syrup
ManufacturerS R Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytics
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
If you have a history of peptic ulcer, inform your doctor before use.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine is rapidly absorbed from the gastrointestinal tract after oral administration.
DistributionIt is widely distributed in the body, with high concentrations in the lungs, liver, and kidneys.
Protein BindingApproximately 99% of bromhexine is bound to plasma proteins.
MetabolismBromhexine undergoes extensive first-pass metabolism in the liver, primarily by cytochrome P450 enzymes, to active metabolites.
Half-LifeThe elimination half-life of bromhexine is approximately 1-2 hours, but its active metabolites have a longer half-life.
ExcretionBromhexine and its metabolites are mainly excreted in the urine.
BioavailabilityThe oral bioavailability of bromhexine is low, approximately 20%, due to first-pass metabolism.
Onset of ActionThe onset of action is typically within 30 minutes to 1 hour after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1 hour after oral administration.
Duration of ActionThe duration of action is approximately 6-8 hours.

How It Works

Bromhexine works by increasing the production of serous fluid in the respiratory tract and breaking down the structure of acidic mucopolysaccharide fibers in mucus. This reduces the viscosity of mucus, making it thinner and easier to expel. It also stimulates the production of surfactant, which helps to keep the airways open.

Mechanism Steps

1
Penetration into mucus: Bromhexine reaches the respiratory tract and comes into contact with mucus.
2
Breakdown of mucus fibers: It breaks down the acidic mucopolysaccharide fibers, reducing mucus viscosity.
3
Increased serous fluid: It stimulates the production of serous fluid, further thinning the mucus.
4
Enhanced clearance: Thinned mucus is more easily cleared by coughing and mucociliary action.

💡 How to Take mucospel syrup

Strength: Bromhexine syrup is available in various strengths, typically 4 mg/5 ml or 8 mg/5 ml. The specific strength of this product is not provided.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the prescribed dose accurately.
3Take the syrup orally, with or without food.
4Follow the dosage schedule prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 8-16 mg (10-20 ml of syrup) three times a day. However, the dose may vary depending on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but caution is advised due to potential reduced liver or kidney function. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment, dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 48 mg (60 ml of syrup) for adults, but this may vary. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of mucospel syrup

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (1-10%))
Stay hydrated. If vomiting is severe or persistent, contact your doctor.
Diarrhea (Common (1-10%))
Drink plenty of fluids. If diarrhea is severe or lasts more than a few days, consult your doctor.
Stomach discomfort (Common (1-10%))
Take with meals. If discomfort continues, talk to your doctor.
Headache (Uncommon (0.1-1%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Peptic ulcer (Rare (<0.1%))
Report symptoms such as severe stomach pain, black stools, or vomiting blood to your doctor immediately.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in the mouth.

⚠️ Rare Side Effects

Dizziness
Avoid driving or operating machinery if affected. Consult your doctor if it persists.
Sweating
Usually resolves on its own. If excessive, consult your doctor.
Skin rash
Discontinue use and consult your doctor if rash develops.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Amoxicillin Moderate
Guaifenesin Minor

🚨 Major Interactions

  • Antitussives (e.g., codeine)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, cefuroxime)

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach irritation and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to bromhexine or any component of the syrup","Peptic ulcer disease","Severe liver disease","Severe kidney disease"]

⚠️ Warnings & Precautions

["Do not use for prolonged periods without medical advice.","Caution in patients with a history of peptic ulcer.","Caution in patients with severe liver or kidney impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Not recommended for children under 2 years without medical advice."]

🤱 Lactation Safety

It is not known whether bromhexine passes into breast milk. Consult your doctor before use.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. Seek immediate medical attention if overdose is suspected. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. If you have a history of peptic ulcer, liver disease, or kidney disease, inform your doctor before taking this medicine. Avoid taking this medicine if you are allergic to bromhexine or any other ingredients. If you are pregnant or breastfeeding, consult your doctor before use. Do not use this medicine for more than 14 days without consulting a doctor. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use if the syrup is discolored or has particles. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and gastrointestinal upset. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of bromhexine during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before taking this medicine, as it may affect mucus clearance and interact with other medications.

🦷 Dental Procedures

No specific precautions for dental procedures. However, inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice good hand hygiene to prevent infections.
🧘
Get plenty of rest to support recovery.

🏋️ Exercise Considerations

If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe the throat.
Include foods rich in vitamin C to support immune function.
Avoid dairy products if they seem to thicken mucus.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal daily activities, but take precautions if you feel drowsy.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects. Do not stop prescribed medication without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine beyond 14 days is not recommended without medical supervision. Prolonged use may lead to gastrointestinal disturbances. Regular monitoring by a doctor is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Rinsing nasal passages with saline solution can help clear mucus.

Evidence: Well-established
Honey

A spoonful of honey can soothe cough and throat irritation.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place, away from direct sunlight. If traveling across time zones, continue with your regular dosing schedule as prescribed. Check customs regulations for carrying medicines. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic bronchitis
Started this medicine as prescribed for thick mucus and persistent cough. Within a few days, noticed that coughing became more productive and easier. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retiree with COPD
Used this medicine as an adjunct to other treatments. Found it helpful in clearing mucus, making breathing easier. Experienced mild nausea initially, which subsided after taking it with meals.
💡 Lesson: Taking the medicine with food can minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 30 minutes to 1 hour after taking a dose. You may notice relief from chest congestion as mucus thins.

Q: Can I take this medicine with antibiotics?

A: Yes, this medicine can be taken with antibiotics. In fact, it may enhance the penetration of certain antibiotics into lung tissue. However, always consult your doctor before combining medicines.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children under 2 years without medical advice. For older children, consult a pediatrician for appropriate dosing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for mucospel syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any cough.
    Fact: This medicine is specifically for productive coughs with thick mucus. It is not effective for dry coughs or coughs due to other causes.
  • Myth: It is safe to take this medicine for as long as you want.
    Fact: Prolonged use without medical supervision is not recommended. Consult a doctor if symptoms persist beyond 14 days.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine syrup (generic)

Brand Alternatives

  • Bisolvon
  • Bromhexine
  • Mucolyte
  • Bromex

📊 Comparison with Similar Medicines

[{"medicine":"Bromhexine","class":"Mucolytic","uses":"Thick mucus, productive cough","onset":"30-60 min"},{"medicine":"Ambroxol","class":"Mucolytic","uses":"Thick mucus, productive cough","onset":"30-60 min"},{"medicine":"Guaifenesin","class":"Expectorant","uses":"Thin mucus, productive cough","onset":"30 min"}]

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