Bisolvon Syrup (Bromhexine): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is bisolvon syrup used for?
This medicine is a mucolytic syrup containing bromhexine, used to thin and loosen mucus in the airways, making it easier to cough out. It is commonly used for productive coughs associated with bronchitis and other respiratory conditions.
- Generic Name: Bromhexine (NA)
- Manufacturer: Zydus Cadila
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bisolvon syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमहेक्सिन सिरप है, जो कफ को पतला करने और बलगम को आसानी से बाहर निकालने में मदद करती है। इसका उपयोग ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं में गाढ़े बलगम के कारण होने वाली खांसी के इलाज के लिए किया जाता है। यह दवा बलगम को पतला करके श्वसन मार्ग को साफ करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असुविधा, सिरदर्द, चक्कर आना और पसीना आना शामिल हो सकते हैं। कभी-कभी एलर्जी प्रतिक्रियाएं जैसे दाने, खुजली या चेहरे, होंठ या गले में सूजन हो सकती है। यदि कोई गंभीर या लगातार दुष्प्रभाव हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। यदि आपको पेप्टिक अल्सर, लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। यदि आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। 14 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें। बच्चों की पहुंच से दूर रखें। ठंडी, सूखी जगह पर स्टोर करें।
💊 bisolvon syrup Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps to thin and loosen mucus in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Used as a mucolytic to relieve symptoms of acute or chronic bronchitis with excessive mucus.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May be used to help clear mucus in patients with COPD, though it is not a primary treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to help thin mucus in sinusitis, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Productive cough
Also treats: Bronchitis, COPD
📋 Drug Information
| Generic Name(s) | Bromhexine (NA) |
| Brand Name | bisolvon syrup |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Mucolytics |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Bromhexine works by increasing the production of serous fluid in the respiratory tract and breaking down the structure of acidic mucopolysaccharide fibers in mucus. This reduces the viscosity of mucus, making it thinner and easier to expel. It also stimulates the production of surfactant, which helps to keep the airways open.
Mechanism Steps
💡 How to Take bisolvon syrup
Strength: Bromhexine syrup is available in various strengths, typically 4 mg/5 ml or 8 mg/5 ml. The specific strength of this product is not provided.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 8-16 mg (10-20 ml of syrup) three times a day. However, the dose may vary depending on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but caution is advised due to potential reduced liver or kidney function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with severe renal impairment, dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with severe hepatic impairment, dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 48 mg (60 ml of syrup) for adults, but this may vary. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bisolvon syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Amoxicillin | Moderate | |
| Guaifenesin | Minor |
🚨 Major Interactions
- Antitussives (e.g., codeine)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, cefuroxime)
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach irritation and dizziness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to bromhexine or any component of the syrup","Peptic ulcer disease","Severe liver disease","Severe kidney disease"]
⚠️ Warnings & Precautions
["Do not use for prolonged periods without medical advice.","Caution in patients with a history of peptic ulcer.","Caution in patients with severe liver or kidney impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Not recommended for children under 2 years without medical advice."]
🤱 Lactation Safety
It is not known whether bromhexine passes into breast milk. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. Seek immediate medical attention if overdose is suspected. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. If you have a history of peptic ulcer, liver disease, or kidney disease, inform your doctor before taking this medicine. Avoid taking this medicine if you are allergic to bromhexine or any other ingredients. If you are pregnant or breastfeeding, consult your doctor before use. Do not use this medicine for more than 14 days without consulting a doctor. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use if the syrup is discolored or has particles. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and gastrointestinal upset. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of bromhexine during pregnancy is not well established.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, consult your doctor before taking this medicine, as it may affect mucus clearance and interact with other medications.
🦷 Dental Procedures
No specific precautions for dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal daily activities, but take precautions if you feel drowsy.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects. Do not stop prescribed medication without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine beyond 14 days is not recommended without medical supervision. Prolonged use may lead to gastrointestinal disturbances. Regular monitoring by a doctor is advised if extended use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Inhaling steam can help loosen mucus and relieve congestion.
Evidence: Well-establishedRinsing nasal passages with saline solution can help clear mucus.
Evidence: Well-establishedA spoonful of honey can soothe cough and throat irritation.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place, away from direct sunlight. If traveling across time zones, continue with your regular dosing schedule as prescribed. Check customs regulations for carrying medicines. Keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 30 minutes to 1 hour after taking a dose. You may notice relief from chest congestion as mucus thins.
A: Yes, this medicine can be taken with antibiotics. In fact, it may enhance the penetration of certain antibiotics into lung tissue. However, always consult your doctor before combining medicines.
A: This medicine is not recommended for children under 2 years without medical advice. For older children, consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🔄 Substitutes for bisolvon syrup
View AllAlternative brands with exact same active ingredient:
-
mucospel syrupS R Pharmaceuticals ₹43.13 24.4% COSTLIER
-
bromex kid syrupHygeia Pharmaceuticals ₹48.46 39.8% COSTLIER
-
theosal pd syrupMonichem Healthcare Pvt Ltd ₹56.25 62.2% COSTLIER
-
brohex syrupBiochem Pharmaceutical Industries ₹77.16 122.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any cough.
Fact: This medicine is specifically for productive coughs with thick mucus. It is not effective for dry coughs or coughs due to other causes. - Myth: It is safe to take this medicine for as long as you want.
Fact: Prolonged use without medical supervision is not recommended. Consult a doctor if symptoms persist beyond 14 days.
🔄 Alternative Options
Generic Alternatives
- Bromhexine syrup (generic)
Brand Alternatives
- Bisolvon
- Bromhexine
- Mucolyte
- Bromex