Ismo 20 Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not go away with rest or fast-acting nitrates
- Fainting or loss of consciousness
- Severe dizziness or lightheadedness
- Bluish lips or skin, confusion, or shortness of breath
- Severe headache that does not improve
- Signs of an allergic reaction such as rash, itching, or swelling of the face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is monicor 20mg tablet used for?
This medicine is a nitrate used to prevent chest pain (angina) in people with heart conditions. It works by relaxing blood vessels to improve blood flow to the heart. It is not for immediate relief of an ongoing angina attack.
- Generic Name: Isosorbide Mononitrate (20mg)
- Manufacturer: Wallace Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 monicor 20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) को रोकने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर दिल तक रक्त का प्रवाह बढ़ाती है और दिल पर दबाव कम करती है। यह दवा तीव्र एंजाइना के दौरे के इलाज के लिए नहीं है, बल्कि दौरे पड़ने की आवृत्ति को कम करने के लिए नियमित रूप से ली जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, और चेहरे पर गर्मी लगना शामिल हैं। ये आमतौर पर शुरुआत में होते हैं और धीरे-धीरे कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको बहुत कम रक्तचाप, बेहोशी, या दिल की धड़कन तेज होने का अनुभव हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा की खुराक खुद से न बदलें और न ही बंद करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। उठते समय धीरे-धीरे उठें। यदि आपको तीव्र एंजाइना का दौरा पड़े तो तुरंत अपनी तेज काम करने वाली दवा लें और डॉक्टर से संपर्क करें।
💊 monicor 20mg tablet Uses & Benefits
[{"condition":"Prevention of angina pectoris","description":"This medicine is used to reduce the frequency and severity of angina attacks in patients with coronary artery disease.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"It helps improve exercise tolerance and reduces the need for short-acting nitrates in patients with stable angina.","evidence":"Well-established"},{"condition":"Vasospastic angina","description":"It may be used to prevent coronary artery spasms in patients with vasospastic angina.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Heart failure","description":"Sometimes used in combination with hydralazine for heart failure, especially in certain patient populations.","evidence":"Moderate"},{"condition":"Esophageal spasm","description":"May be used off-label to relieve esophageal spasm-related chest pain.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Heart failure (off-label)
📋 Drug Information
| Generic Name(s) | Isosorbide Mononitrate (20mg) |
| Brand Name | monicor 20mg tablet |
| Manufacturer | Wallace Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | Not established from the available information. Refer to the packaging for the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by releasing nitric oxide, which activates an enzyme called guanylate cyclase in smooth muscle cells. This leads to an increase in cyclic guanosine monophosphate (cGMP), which causes relaxation of vascular smooth muscle. The relaxation of veins and arteries reduces the workload on the heart and improves blood flow to the heart muscle, thereby preventing angina.
Mechanism Steps
💡 How to Take monicor 20mg tablet
Strength: Isosorbide Mononitrate 20 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 20 mg taken once or twice daily, depending on the indication and your doctor's assessment. The dose may be increased gradually to a maximum of 40 mg twice daily, but the exact dose must be individualized by a qualified clinician based on your condition, age, and other medications. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Your doctor may start with a lower dose and monitor you closely. |
| Renal Impairment | No specific dose adjustment is established from the available information. Use with caution in patients with severe renal impairment. |
| Hepatic Impairment | No specific dose adjustment is established from the available information. Use with caution in patients with severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 80 mg (40 mg twice daily), but this must be determined by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of monicor 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Riociguat | Major | |
| Alcohol | Moderate | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Ergot alkaloids | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)
- Riociguat
⚡ Moderate Interactions
- Alcohol
- Antihypertensives (e.g., beta-blockers, calcium channel blockers)
- Ergot alkaloids
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine and may cause dizziness, lightheadedness, or fainting. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to isosorbide mononitrate or other nitrates","Severe hypotension (low blood pressure)","Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)","Concomitant use with riociguat","Increased intracranial pressure","Severe anemia","Hypovolemia"]
⚠️ Warnings & Precautions
["This medicine may cause severe hypotension, especially when standing up. Rise slowly.","Tolerance to the effects can develop with continuous use. A nitrate-free interval is often recommended.","Avoid alcohol while taking this medicine.","Use with caution in patients with glaucoma.","Use with caution in patients with severe liver or kidney disease.","Do not use this medicine to treat an acute angina attack. Use fast-acting nitrates for acute attacks."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe hypotension, headache, dizziness, palpitations, and fainting. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including measures to support blood pressure and heart rate.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. To reduce the risk of tolerance, your doctor may prescribe a nitrate-free interval, usually at night. Avoid alcohol while taking this medicine, as it can increase the blood pressure-lowering effect and cause dizziness. Stand up slowly from a sitting or lying position to prevent lightheadedness. If you have an acute angina attack, use your fast-acting nitrate (such as sublingual nitroglycerin) as instructed, and seek emergency help if the pain persists. Inform all your healthcare providers that you are taking this medicine, especially before surgery or dental procedures. Store this medicine at room temperature, away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Your doctor may start with a lower dose and monitor you closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with medications used during surgery and affect blood pressure.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or lightheadedness, especially when you start treatment or change doses. Avoid strenuous exercise until you know how the medicine affects you. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Inform your employer if your job involves such tasks.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition changes, your doctor may adjust or stop the medicine. Always follow medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, where the medicine becomes less effective. To prevent this, doctors often recommend a nitrate-free interval. Regular monitoring of blood pressure and heart rate is advised. Do not stop the medicine suddenly without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, regular exercise, and stress management can complement medicine for angina.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, or ranolazine may be alternatives or additions.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccinations while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust the timing of doses gradually as advised by your doctor. Store at room temperature and protect from moisture. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes after taking a dose, but its full preventive effect may take a few days of regular use.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for monicor 20mg tablet
View AllAlternative brands with exact same active ingredient:
-
insocalm 20mg tabletSun Pharmaceutical Industries Ltd ₹8.78 51.7% CHEAPER
-
angifree 20mg tabletMicro Labs Ltd ₹11.54 36.6% CHEAPER
-
davaindia isosorbide mononitrate 20mg tabletDavaindia Generic Pharmacy ₹13.00 28.5% CHEAPER
-
monex 20mg tabletRedson Laboratories Pvt Ltd ₹16.41 9.8% CHEAPER
-
Sormo 20mg TabletMano Pharma Pvt Ltd ₹18.66 2.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken to relieve an acute angina attack.
Fact: This medicine is for prevention, not for immediate relief of an ongoing attack. Use fast-acting nitrates for acute attacks. - Myth: You can take this medicine with erectile dysfunction drugs.
Fact: Combining this medicine with erectile dysfunction drugs can cause a dangerous drop in blood pressure and is contraindicated.
🔄 Alternative Options
Generic Alternatives
- Isosorbide Mononitrate 20 mg tablet
Brand Alternatives
- Ismo 20 Tablet