Angicor 20mg Tablet (isosorbide Mononitrate): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not respond to rest or fast-acting nitrates
- Fainting or severe dizziness
- Bluish lips or skin, confusion, or shortness of breath
- Severe headache that does not improve
- Rash, itching, or swelling of the face, lips, or throat
- Slow or irregular heartbeat
- Sudden increase in the frequency or severity of angina attacks
If experiencing severe symptoms, call emergency services immediately.
What is angifree 20mg tablet used for?
This medicine is an oral nitrate used to prevent angina attacks. It works by relaxing blood vessels to improve blood flow to the heart. It is not for immediate relief of an ongoing angina attack.
- Generic Name: Isosorbide Mononitrate
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 angifree 20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) के दौरों को रोकने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त का प्रवाह बढ़ाती है और हृदय पर दबाव कम करती है। यह दवा तीव्र एंजाइना के दौरे के तत्काल उपचार के लिए नहीं है। इसका उपयोग दिल की बीमारी वाले रोगियों में लंबे समय तक एंजाइना को रोकने के लिए किया जाता है।
साइड इफेक्ट्स: सबसे आम दुष्प्रभाव सिरदर्द है, जो आमतौर पर इलाज शुरू करने पर होता है और समय के साथ कम हो जाता है। अन्य सामान्य दुष्प्रभावों में चक्कर आना, हल्का सिर घूमना, चेहरे पर लालिमा और दिल की धड़कन तेज होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप, बेहोशी और एलर्जी प्रतिक्रिया शामिल हो सकती है।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। दवा की खुराक बदलें या बंद करें नहीं। सहनशीलता से बचने के लिए डॉक्टर द्वारा बताए गए नाइट्रेट-मुक्त अंतराल का पालन करें। शराब से बचें क्योंकि इससे रक्तचाप कम हो सकता है और चक्कर आ सकते हैं। सिल्डेनाफिल, टैडालाफिल जैसी दवाएं इस दवा के साथ न लें। बैठने या लेटने से उठते समय धीरे-धीरे उठें। किसी भी सर्जरी या दंत प्रक्रिया से पहले अपने डॉक्टर को इस दवा के बारे में बताएं।
💊 angifree 20mg tablet Uses & Benefits
[{"condition":"Prevention of angina pectoris","description":"Used for long-term prophylaxis of angina attacks in patients with coronary artery disease.","evidence":"Well-established"},{"condition":"Heart failure (adjunct)","description":"May be used as part of combination therapy in chronic heart failure to reduce symptoms and improve exercise tolerance.","evidence":"Moderate"},{"condition":"Esophageal spasm","description":"Sometimes used to relieve esophageal spasm, though this is not a primary indication.","evidence":"Limited"}]
Off-label uses: [{"condition":"Raynaud's phenomenon","description":"Occasionally used to improve blood flow in Raynaud's phenomenon, but evidence is limited.","evidence":"Limited"},{"condition":"Prevention of contrast-induced nephropathy","description":"Investigated for prevention of kidney damage from contrast dyes, but not standard practice.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Heart failure, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Isosorbide Mononitrate |
| Brand Name | Angicor |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Isosorbide mononitrate is a nitrate that is converted in the body to nitric oxide, which activates guanylate cyclase. This leads to increased cyclic GMP, causing relaxation of vascular smooth muscle. The result is dilation of veins and arteries, which reduces preload and afterload on the heart, lowering myocardial oxygen demand and improving blood flow to the heart muscle.
Mechanism Steps
💡 How to Take angifree 20mg tablet
Strength: Isosorbide Mononitrate 20 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 20 mg once daily or as directed by your doctor. For angina prophylaxis, the dose may be increased to 40 mg or 60 mg once daily based on response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a low dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor closely. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 120 mg, but doses above 80 mg are rarely used. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of angifree 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Riociguat | Major | |
| Metoprolol | Moderate | |
| Amlodipine | Moderate | |
| Lisinopril | Moderate | |
| Amitriptyline | Moderate | |
| Ibuprofen | Minor | |
| Alcohol | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- Riociguat
⚡ Moderate Interactions
- Antihypertensives (e.g., beta-blockers, calcium channel blockers, ACE inhibitors)
- Alcohol
- Tricyclic antidepressants
🍷 Alcohol Interaction
Alcohol can enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol or limit its intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to isosorbide mononitrate or other nitrates","Severe hypotension (systolic blood pressure
⚠️ Warnings & Precautions
["Do not use for acute angina attacks; use a fast-acting nitrate for immediate relief.","Tolerance to the effects can develop; maintain a nitrate-free interval as prescribed.","Avoid abrupt discontinuation; may cause rebound angina.","Use with caution in patients with low blood pressure or volume depletion.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have liver or kidney disease.","Alcohol may enhance the hypotensive effect; avoid or limit intake."]
🤱 Lactation Safety
Isosorbide mononitrate is excreted in breast milk. Caution is advised when used during breastfeeding. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose can cause severe hypotension, headache, dizziness, palpitations, and fainting. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic, including placing the patient in a supine position with legs elevated, and administering intravenous fluids if necessary. Methemoglobinemia may be treated with methylene blue if indicated.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily or as directed. Do not change the dose or stop taking it without consulting your doctor. To avoid tolerance, your doctor may prescribe a nitrate-free interval, often at night. Rise slowly from sitting or lying down to prevent dizziness. Avoid alcohol, as it can increase the blood pressure-lowering effect and cause dizziness. Do not take erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil while on this medicine, as this can cause a dangerous drop in blood pressure. Inform all healthcare providers that you take this medicine before any surgery or dental procedure. Store the tablets at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a low dose and monitor blood pressure regularly. Rise slowly to prevent falls.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine should be used only if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with medications used during surgery and affect blood pressure.
🦷 Dental Procedures
Inform your dentist that you take this medicine before any dental procedure. It may affect blood pressure and interact with local anesthetics containing vasoconstrictors.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activities that may trigger angina. Consult your doctor before starting any new exercise program. Stop and rest if you experience chest pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition changes, your doctor may adjust or discontinue the medicine. Abrupt withdrawal can worsen angina.
📅 Long-Term Use Effects
Long-term use may lead to tolerance if a nitrate-free interval is not maintained. Regular monitoring of blood pressure, heart rate, and angina frequency is recommended. Periodic review with your doctor is necessary to adjust the dose and assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be used for angina prophylaxis and may be combined with nitrates.
Evidence: Well-establishedAlternative or add-on therapy for angina prevention.
Evidence: Well-establishedDiet, exercise, and stress reduction complement medical therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor about this medicine before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes after oral administration, but its full preventive effect may take a few days.
A: No, this medicine is for prevention. For an acute attack, use a fast-acting nitrate as prescribed by your doctor.
A: No, stopping suddenly can cause rebound angina. Consult your doctor before stopping.
🤔 Common Patient Concerns
🔄 Substitutes for angifree 20mg tablet
View AllAlternative brands with exact same active ingredient:
-
insocalm 20mg tabletSun Pharmaceutical Industries Ltd ₹8.78 23.9% CHEAPER
-
davaindia isosorbide mononitrate 20mg tabletDavaindia Generic Pharmacy ₹13.00 12.7% COSTLIER
-
monex 20mg tabletRedson Laboratories Pvt Ltd ₹16.41 42.2% COSTLIER
-
monicor 20mg tabletWallace Pharmaceuticals Pvt Ltd ₹18.19 57.6% COSTLIER
-
Sormo 20mg TabletMano Pharma Pvt Ltd ₹18.66 61.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate chest pain relief.
Fact: This medicine is for prevention of angina, not for acute attacks. A fast-acting nitrate is used for immediate relief. - Myth: It is safe to take erectile dysfunction medicines with this medicine.
Fact: Combining this medicine with erectile dysfunction medicines can cause a dangerous drop in blood pressure and is contraindicated. - Myth: You can take this medicine continuously without a break.
Fact: A nitrate-free interval is necessary to prevent tolerance and maintain effectiveness.
🔄 Alternative Options
Generic Alternatives
- Isosorbide Mononitrate 20 mg tablet
Brand Alternatives
- Angicor 20mg tablet