Larither 40mg Capsule (Artemether): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Fainting or very slow pulse
- Seizures
- Severe skin rash with blistering or peeling
If experiencing severe symptoms, call emergency services immediately.
What is malither 40mg capsule used for?
This medicine contains Artemether 40mg, an antimalarial used as part of combination therapy to treat uncomplicated malaria caused by Plasmodium falciparum. It works by killing the malaria parasite in the blood. It must be taken exactly as prescribed, usually for 3 days, and should not be used alone.
- Generic Name: Artemether (40mg)
- Manufacturer: Themis Medicare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 malither 40mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा आर्टेमेथर 40mg कैप्सूल के रूप में उपलब्ध है और मलेरिया के इलाज के लिए इस्तेमाल की जाती है। यह प्लास्मोडियम फाल्सीपेरम नामक परजीवी के कारण होने वाले मलेरिया के इलाज में कारगर है। यह दवा अकेले नहीं, बल्कि किसी अन्य मलेरिया-रोधी दवा के साथ मिलाकर दी जाती है ताकि परजीवी में प्रतिरोधक क्षमता विकसित न हो। यह दवा खून में मौजूद मलेरिया परजीवी को मारती है, जिससे बुखार, ठंड लगना और पसीना आना जैसे लक्षण कम होते हैं। इसे डॉक्टर के बताए अनुसार पूरा कोर्स करना बहुत जरूरी है, भले ही आपको जल्दी आराम महसूस होने लगे।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, चक्कर आना, जी मिचलाना, उल्टी, पेट दर्द और भूख न लगना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी दिल की धड़कन धीमी हो सकती है या एलर्जी हो सकती है। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, पीलिया, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो और दवा अच्छी तरह अवशोषित हो। इस दवा के साथ शराब न लें। अपने डॉक्टर को अपनी सभी दवाओं, खासकर दिल और लीवर से जुड़ी दवाओं के बारे में बताएं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर रखें और मूल डिब्बे में ही स्टोर करें।
💊 malither 40mg capsule Uses & Benefits
[{"condition":"Acute uncomplicated Plasmodium falciparum malaria","description":"This medicine is used as part of artemisinin-based combination therapy to treat uncomplicated malaria caused by Plasmodium falciparum, reducing parasite load and resolving symptoms such as fever and chills.","evidence":"Well-established"},{"condition":"Severe malaria (in combination, in hospital settings)","description":"In severe malaria, artemether is often given by injection initially, but oral artemether may be used to complete treatment after stabilization, always in combination with another antimalarial.","evidence":"Well-established"},{"condition":"Malaria due to other Plasmodium species (when appropriate)","description":"This medicine may be used for other malaria species in combination therapy, but it is not the preferred treatment for Plasmodium vivax because a radical cure with primaquine is also needed.","evidence":"Limited"}]
Off-label uses: [{"condition":"Not established from the available information.","description":"There are no widely accepted off-label uses for this medicine outside of malaria treatment.","evidence":"Not established from the available information."}]
Primary treatment for: Malaria
Also treats: Plasmodium falciparum malaria, Severe malaria (after stabilization)
📋 Drug Information
| Generic Name(s) | Artemether (40mg) |
| Brand Name | malither 40mg capsule |
| Manufacturer | Themis Medicare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial- Artemisinin and derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep in the original container, away from direct sunlight and moisture. Do not refrigerate unless specified on the label. |
| Shelf Life | Typically 24 months from the date of manufacture, but check the expiry date on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization recommends artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated Plasmodium falciparum malaria. Artemether is one of the artemisinin derivatives used in ACTs. The specific combination and dosing should follow national guidelines. |
| ICMR Guideline | The Indian Council of Medical Research recommends artemisinin-based combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria in India. The choice of ACT should be based on national guidelines and local resistance patterns. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Artemether is a prodrug that is converted in the body to its active metabolite, dihydroartemisinin. This active metabolite contains an endoperoxide bridge that reacts with iron-containing molecules inside the malaria parasite, generating highly reactive free radicals. These free radicals damage the parasite's proteins, membranes, and other essential molecules, leading to rapid parasite death. Artemether is effective against the blood stages of the malaria parasite, which are responsible for the symptoms of the disease.
Mechanism Steps
💡 How to Take malither 40mg capsule
Strength: Artemether 40mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is determined by your doctor based on the type of malaria, your weight, and other factors. It is typically taken once or twice daily for 3 days as part of combination therapy. The exact dose and duration must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and heart rhythm changes. Dose adjustment may be needed based on kidney and liver function. Consult your doctor for personalized dosing. |
| Renal Impairment | No specific dose adjustment is established for patients with kidney impairment, but use with caution in severe kidney disease. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose adjustment may be needed. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum daily dose is determined by your doctor based on your condition and weight. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of malither 40mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Amiodarone | Major | |
| Lumefantrine | Major | |
| Warfarin | Moderate | |
| Grapefruit juice | Moderate | |
| Hormonal contraceptives | Moderate | |
| Antacids | Minor | |
| Carbamazepine | Major | |
| Ritonavir | Major |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine)
- Other antimalarials (e.g., lumefantrine, mefloquine)
- Drugs that prolong QT interval (e.g., amiodarone, sotalol, certain antipsychotics)
⚡ Moderate Interactions
- Grapefruit juice
- Hormonal contraceptives
- Warfarin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and liver problems. It may also worsen the side effects of artemether.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to artemether or other artemisinin derivatives","First trimester of pregnancy (unless life-threatening situation and no safer alternative)","Severe malaria requiring immediate injectable therapy (oral form not suitable initially)","Use as monotherapy for malaria (must be combined with another antimalarial)"]
⚠️ Warnings & Precautions
["Take this medicine exactly as prescribed and complete the full course.","Do not use as a single medicine for malaria; combination therapy is essential.","Avoid alcohol while taking this medicine.","Inform your doctor if you have heart, liver, or kidney problems.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid driving or operating machinery if you feel dizzy.","Keep out of reach of children.","Store in original container away from direct sunlight and moisture."]
🤱 Lactation Safety
It is not known whether artemether passes into breast milk in significant amounts. Consult your doctor before breastfeeding while taking this medicine. Your doctor will weigh the benefits of treatment against the potential risks to the infant.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe dizziness, slow heart rate, nausea, and vomiting. Treatment is supportive and symptomatic. There is no specific antidote for artemether overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you vomit within 30 minutes of taking a dose, consult your doctor; you may need to take another dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, and do not stop early even if you feel better, because completing the full course is essential to cure malaria and prevent relapse. Swallow the capsule whole with water, and take it with food to improve absorption and reduce stomach upset. Avoid alcohol while taking this medicine, as it may worsen dizziness and liver stress. Inform your doctor about all other medicines you take, especially other antimalarials, heart rhythm medicines, and drugs that affect liver enzymes. Do not share this medicine with anyone else, even if they have similar symptoms. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before taking this medicine. Keep this medicine out of reach of children, and store it in its original container away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, slow heart rate, and liver problems. Dose adjustment may be needed based on kidney and liver function. Close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Artemether is generally avoided during the first trimester. If you become pregnant while taking this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medicines used during surgery. Your doctor will advise you on whether to continue or temporarily stop the medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain medicines used in dentistry. Your dentist may advise you to postpone non-urgent procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may feel dizzy or weak. Avoid strenuous exercise until you have fully recovered from malaria. Light activities like walking are fine if you feel up to it. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness and fatigue, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. You may need to take rest from work while recovering from malaria. Consult your doctor before resuming normal activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. You must complete the full prescribed course, even if you feel better, to ensure the malaria parasite is completely cleared. If you experience severe side effects, contact your doctor immediately; they will advise you on whether to stop or adjust the treatment.
📅 Long-Term Use Effects
This medicine is usually taken for a short duration (typically 3 days) to treat malaria. Long-term effects are not well established because it is not intended for prolonged use. However, if used for extended periods, it may rarely cause liver enzyme elevations or heart rhythm changes. Regular monitoring may be required if prolonged use is necessary. Always consult your doctor before taking this medicine for longer than prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Alternatives like artesunate-amodiaquine or artemether-lumefantrine may be used depending on local guidelines and availability.
Evidence: Well-establishedIn areas where artemisinin resistance is a concern, other antimalarials may be used, but they are generally less effective.
Evidence: LimitedUsing mosquito nets, repellents, and preventive medicines can help avoid malaria.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for a vaccine, inform your doctor that you are taking this medicine. Live vaccines should be avoided during acute illness, including malaria.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough medicine for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 24 to 48 hours, reducing fever and parasite load. However, you must complete the full course as prescribed to ensure a complete cure.
A: It is best to take this medicine with food, especially fatty food, as it improves absorption and reduces stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is generally avoided during the first trimester. In the second and third trimesters, it may be used under medical supervision if the benefits outweigh the risks. Consult your doctor.
A: It is advisable to avoid alcohol while taking this medicine, as it can increase dizziness and liver stress.
🤔 Common Patient Concerns
🔄 Substitutes for malither 40mg capsule
View AllAlternative brands with exact same active ingredient:
-
malether 40mg injectionUnicure India Pvt Ltd ₹70.31 36.1% CHEAPER
-
orther 40 injectionJohnlee Pharmaceuticals Pvt Ltd ₹98.44 10.5% CHEAPER
-
Rmether 40mg CapsuleTrends Pharma Pvt Ltd ₹108.00 1.8% CHEAPER
-
Rezart M 40mg CapsuleShreya Life Sciences Pvt Ltd ₹110.00 SAME PRICE
-
larither 40mg capsuleIpca Laboratories Ltd ₹121.88 10.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Artemether can be taken alone to treat malaria.
Fact: Artemether should always be used in combination with another antimalarial medicine to prevent resistance and ensure complete cure. - Myth: You can stop taking artemether once you feel better.
Fact: You must complete the full course as prescribed, even if you feel better, to ensure the parasite is completely cleared. - Myth: Artemether is safe to take without a prescription.
Fact: Artemether is a prescription medicine and should only be taken under medical supervision. - Myth: Artemether can prevent malaria.
Fact: Artemether treats malaria but does not prevent it. Preventive measures like mosquito nets and repellents are important.
🔄 Alternative Options
Generic Alternatives
- Artemether 40mg capsule
Brand Alternatives
- Larither 40mg capsule