aquadol spas 20mg/50mg injection - Uses, Price, Side Effects & Substitutes
What is aquadol spas 20mg/50mg injection used for?
Aquadol Spas 20mg/50mg Injection (Dicyclomine + Diclofenac) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (20mg) + Diclofenac (50mg), which Dicyclomine blocks muscarinic acetylcholine receptors, reducing smooth muscle sp. Always consult your doctor before use. Take as prescribed.
- Generic Name: Dicyclomine + Diclofenac
- Manufacturer: Themis Medicare Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aquadol spas 20mg/50mg injection Uses & Benefits
๐ Drug Information
| Generic Name(s) | Dicyclomine + Diclofenac |
| Brand Name | Aquadol Spas 20mg/50mg Injection |
| Manufacturer | Themis Medicare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Intramuscular injection |
| Storage | Store at room temperature (20-25ยฐC); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Dicyclomine blocks muscarinic acetylcholine receptors, reducing smooth muscle spasms; Diclofenac inhibits cyclooxygenase (COX-1 and COX-2), decreasing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take aquadol spas 20mg/50mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aquadol spas 20mg/50mg injection
โ Common Side Effects
- Nausea
- Dizziness
- Dry mouth
- Blurred vision
- Constipation
- Headache
- Injection site pain
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Renal failure
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Aplastic anemia
- Pancreatitis
- Hearing loss
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Diuretics | Major | Reduced diuretic effect, increased nephrotoxicity |
| Anticoagulants | Major | Increased bleeding risk |
| Aspirin | Moderate | Increased GI side effects |
| Corticosteroids | Moderate | Increased GI ulceration risk |
| SSRIs | Moderate | Increased bleeding risk |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Tacrolimus | Moderate | Increased nephrotoxicity |
| Antacids | Minor | Reduced absorption of diclofenac |
| Cholestyramine | Minor | Reduced absorption of diclofenac |
| Digoxin | Minor | Increased digoxin levels |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
- Anticoagulants
โก Moderate Interactions
- Aspirin
- Corticosteroids
- SSRIs
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Digoxin
๐ฝ๏ธ Food Interactions
Avoid alcohol; may increase GI irritation.
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; active GI bleeding; severe hepatic or renal impairment; history of asthma, urticaria, or allergic reactions to NSAIDs; third trimester pregnancy; coronary artery bypass graft surgery.
๐ Monitoring Parameters
Renal function, hepatic function, blood pressure, signs of GI bleeding, and CNS effects.
๐คฑ Lactation Safety
Use with caution; both drugs excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; induce emesis or gastric lavage if oral; monitor for CNS depression, respiratory depression, seizures, and GI bleeding.
โฐ Missed Dose
Administer as soon as remembered; if close to next dose, skip missed dose.