m cold tablet - Paracetamol (NA) + Caffeine (NA) medicine

Dolopar Cc Tablet: Complete Medicine Guide

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🏭 Abbott 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 28, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for paracetamol as an analgesic/antipyretic; caffeine as an adjuvant has moderate evidence.
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of the skin or eyes (jaundice)
  • Dark-colored urine or pale stools
  • Severe abdominal pain or vomiting blood
  • Difficulty breathing or swelling of the face, lips, or throat
  • Unusual bleeding or bruising
  • Persistent fever lasting more than 3 days
  • Severe headache with confusion or vision changes

If experiencing severe symptoms, call emergency services immediately.

What is m cold tablet used for?

This medicine is a combination of paracetamol and caffeine used for short-term relief of mild to moderate pain and fever. It works by reducing pain signals in the brain and enhancing alertness. Take it exactly as prescribed, and do not exceed the recommended dose to avoid liver damage.

  • Generic Name: Paracetamol (NA) + Caffeine (NA)
  • Manufacturer: Abbott
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 m cold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और कैफीन का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मासिक धर्म में होने वाले दर्द, और मांसपेशियों के दर्द में राहत देती है। यह दवा दर्द को कम करने और शरीर के तापमान को नियंत्रित करने में मदद करती है। कैफीन दर्द निवारक प्रभाव को बढ़ाता है और सतर्कता बढ़ाता है। इसका उपयोग केवल डॉक्टर की सलाह पर और सीमित समय के लिए करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, पेट में असहजता, बेचैनी, अनिद्रा और घबराहट शामिल हैं, जो मुख्य रूप से कैफीन के कारण होते हैं। कभी-कभी त्वचा पर चकत्ते या एलर्जी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अत्यधिक मात्रा में लेने पर लीवर को गंभीर नुकसान हो सकता है। यदि आपको पीलिया, गहरे रंग का मूत्र, या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अनुशंसित मात्रा से अधिक न लें, क्योंकि इससे लीवर को गंभीर नुकसान हो सकता है। इस दवा के साथ शराब न पिएं। यदि आपको लीवर या किडनी की बीमारी है, तो डॉक्टर से सलाह लें। बिना डॉक्टर की सलाह के इस दवा को कई दिनों तक न लें। बच्चों की पहुंच से दूर रखें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से परामर्श करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 m cold tablet Uses & Benefits

[{"condition":"Tension headache","description":"Relieves mild to moderate headache pain by inhibiting central prostaglandin synthesis and caffeine-induced vasoconstriction.","evidence":"Well-established"},{"condition":"Migraine","description":"Provides symptomatic relief of migraine pain, with caffeine enhancing the analgesic effect of paracetamol.","evidence":"Well-established"},{"condition":"Dental pain","description":"Used for short-term relief of toothache and post-dental procedure pain.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Helps alleviate dysmenorrhea-related pain and discomfort.","evidence":"Moderate"},{"condition":"Fever","description":"Reduces fever by acting on the hypothalamic heat-regulating center.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Provides relief from mild to moderate pain associated with muscle strains and sprains.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used as an adjunct for mild post-operative pain, but not a first-line option.","evidence":"Limited"},{"condition":"Osteoarthritis pain","description":"May be used for short-term pain relief in osteoarthritis when other analgesics are not suitable.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Migraine, Dental pain, Menstrual cramps, Musculoskeletal pain

📋 Drug Information

Generic Name(s)Paracetamol (NA) + Caffeine (NA)
Brand Namem cold tablet
ManufacturerAbbott
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce the risk of stomach upset.
2
Do not exceed the recommended dose; taking too much paracetamol can cause serious liver damage.
3
Avoid alcohol completely while taking this medicine to prevent liver toxicity.
4
If you are taking blood thinners like warfarin, inform your doctor before using this medicine.
5
Do not use this medicine for more than 3 days for fever or 10 days for pain without consulting a doctor.
6
Keep track of all paracetamol-containing products you take to avoid accidental overdose.
7
If you experience insomnia or restlessness, avoid taking this medicine in the evening.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly used for tension headaches and migraines.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
✅
Toothache
Provides temporary relief from dental pain.
Likely Use
✅
Menstrual cramps
Helps relieve dysmenorrhea.
Likely Use
❌
Chest pain
This medicine is not appropriate for chest pain; seek immediate medical attention.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. Caffeine is also rapidly absorbed. The presence of caffeine may slightly enhance the rate of paracetamol absorption. Food may delay the onset of action.
DistributionParacetamol is distributed widely throughout most body tissues, with a volume of distribution of approximately 0.9 L/kg. It crosses the placenta and is excreted in breast milk. Caffeine is distributed throughout body fluids and tissues, with a volume of distribution of about 0.6 L/kg. It also crosses the placenta and is excreted in breast milk.
Protein BindingParacetamol is minimally bound to plasma proteins (about 10-25%). Caffeine is approximately 10-35% bound to plasma proteins.
MetabolismParacetamol is primarily metabolized in the liver via glucuronidation and sulfation to inactive metabolites. A small fraction is metabolized by cytochrome P450 2E1 to N-acetyl-p-benzoquinone imine (NAPQI), a toxic intermediate that is normally detoxified by glutathione. In overdose, glutathione is depleted, leading to liver damage. Caffeine is metabolized in the liver by cytochrome P450 1A2 to paraxanthine, theobromine, and theophylline, which are further metabolized and excreted.
Half-LifeParacetamol: 2-3 hours in adults; may be prolonged in liver disease. Caffeine: 3-7 hours, with significant inter-individual variation.
ExcretionParacetamol metabolites are excreted primarily in the urine. Less than 5% is excreted unchanged. Caffeine metabolites are excreted in the urine, with only a small amount excreted unchanged.
BioavailabilityParacetamol: approximately 80-100% after oral administration. Caffeine: approximately 99% after oral administration.
Onset of ActionParacetamol: 30-60 minutes for pain relief and fever reduction. Caffeine: 15-45 minutes for stimulant effects.
Peak Plasma TimeParacetamol: 0.5-2 hours. Caffeine: 0.5-2 hours.
Duration of ActionParacetamol: 4-6 hours. Caffeine: 3-5 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system, primarily through actions on cyclooxygenase enzymes in the brain and spinal cord. Caffeine acts as a central nervous system stimulant and vasoconstrictor; it blocks adenosine receptors, which can enhance the analgesic effect of paracetamol and reduce fatigue. Together, they provide more effective pain relief than paracetamol alone for certain types of headaches.

Mechanism Steps

1
Paracetamol inhibits central prostaglandin synthesis: Paracetamol reduces the production of prostaglandins in the brain and spinal cord by inhibiting cyclooxygenase enzymes, leading to decreased pain perception and fever reduction.
2
Caffeine blocks adenosine receptors: Caffeine antagonizes adenosine A1 and A2A receptors in the brain, which leads to increased neuronal firing and release of neurotransmitters like dopamine and norepinephrine, promoting alertness and enhancing pain relief.
3
Caffeine enhances paracetamol absorption: Caffeine may increase gastric emptying and intestinal absorption of paracetamol, leading to faster onset of action.
4
Synergistic analgesic effect: The combined actions result in improved pain relief compared to paracetamol alone, particularly for headaches and mild to moderate pain.

💡 How to Take m cold tablet

Strength: This medicine is available as an immediate-release tablet. The specific strength of paracetamol and caffeine is not provided in the available information.

1Take this medicine orally with a full glass of water.
2You may take it with or without food. Taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not exceed the recommended dose.
5If you are taking other medications, consult your doctor or pharmacist before use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for pain or fever, not exceeding 4 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and other medications being taken. Do not exceed the maximum daily dose. This medicine is intended for short-term use only.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of caffeine and may have reduced liver or kidney function. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, the dose may need to be reduced or the dosing interval increased. Consult a doctor for guidance.
Hepatic ImpairmentIn patients with hepatic impairment, the dose should be reduced or avoided due to the risk of liver toxicity. Consult a doctor for guidance.
Maximum Daily DoseThe maximum daily dose of paracetamol for adults is 4000 mg (4 grams). For this combination, the maximum daily dose is typically 4 tablets in 24 hours, but the exact limit depends on the strength of the tablet. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine-containing foods and beverages
Limit intake
Excessive caffeine can increase side effects like insomnia and palpitations.
Alcohol
Avoid
Increases risk of liver toxicity.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of m cold tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food or milk to reduce stomach upset. If persistent, consult your doctor.
Nervousness or restlessness (Common (1-10%))
Usually due to caffeine. Reduce dose or avoid taking in the evening. Consult doctor if severe.
Insomnia (Common (1-10%))
Avoid taking this medicine close to bedtime. If sleep disturbances persist, consult your doctor.
Stomach discomfort (Common (1-10%))
Take with food. If it continues, talk to your doctor.

🚨 Serious Side Effects

Liver damage (hepatotoxicity) (Rare (<0.1%))
Seek immediate medical attention if you experience yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face, lips, or throat, or a severe rash.
Blood disorders (e.g., thrombocytopenia) (Very rare (<0.01%))
Report unusual bleeding or bruising to your doctor immediately.
Acute pancreatitis (Very rare (<0.01%))
Seek immediate medical care if you have severe upper abdominal pain that radiates to your back.

⚠️ Rare Side Effects

Skin rash or itching
Discontinue use and consult your doctor if rash develops.
Palpitations
Avoid caffeine-containing products and consult your doctor if palpitations occur.
Anxiety
Reduce dose or discontinue if anxiety is bothersome. Consult your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Other paracetamol products Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Fluconazole Moderate
Ketoconazole Moderate
Theophylline Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other paracetamol-containing products

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, rifampicin
  • Fluconazole, ketoconazole
  • Theophylline

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of paracetamol-induced liver damage, especially with chronic use or high doses. It can also exacerbate caffeine-related side effects such as anxiety and palpitations.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to paracetamol, caffeine, or any component of the formulation","Severe hepatic impairment or active liver disease","Severe renal impairment","Chronic alcoholism","G6PD deficiency (for paracetamol, due to risk of hemolysis)"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose; taking more can cause serious liver damage.","Avoid alcohol while taking this medicine.","Do not use for more than 3 days for fever or 10 days for pain without medical advice.","Consult a doctor before use if you have liver or kidney disease, heart disease, or are pregnant or breastfeeding.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Keep out of reach of children.","Do not take with other paracetamol-containing products."]

🤱 Lactation Safety

Paracetamol and caffeine are excreted in breast milk in small amounts. Short-term use at recommended doses is generally considered compatible with breastfeeding. However, caffeine may accumulate in the infant and cause irritability or poor sleep. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite, which may not appear immediately. If you suspect an overdose, seek emergency medical attention immediately, even if you feel well. The antidote, N-acetylcysteine, is most effective when given within 8-10 hours of ingestion. Caffeine overdose can cause insomnia, restlessness, palpitations, and in severe cases, seizures. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose, as excessive paracetamol can cause serious liver damage. Avoid drinking alcohol while taking this medicine, as it increases the risk of liver toxicity. If you have a history of liver or kidney disease, consult your doctor before use. Do not use this medicine for more than a few days for pain or fever without medical advice. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Be cautious when driving or operating machinery if you experience dizziness or drowsiness. Inform your doctor about all other medications you are taking, especially blood thinners like warfarin, as this medicine may interact with them. Do not take this medicine with other products containing paracetamol to avoid overdose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of caffeine and may have reduced liver and kidney function. Use with caution and consult a doctor for appropriate dosing. They may also be at higher risk of drug interactions.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe, but caffeine intake should be limited. High caffeine consumption has been associated with reduced fertility and increased risk of miscarriage.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used for mild pain relief, but it is not a substitute for stronger pain medications if needed. Consult your surgeon before taking any medication post-surgery.

🦷 Dental Procedures

This medicine can be taken for dental pain, but inform your dentist if you are taking it before any dental procedure. It may interact with anesthetics or other medications used during dental work.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and muscles.
🥗
Stay hydrated by drinking plenty of water throughout the day.
😴
Get regular exercise, but avoid overexertion.
💧
Practice stress-reducing techniques such as deep breathing or meditation.
🧘
Ensure adequate sleep to help your body recover.
🌞
Limit caffeine intake from other sources to avoid excessive stimulation.

🏋️ Exercise Considerations

This medicine may cause dizziness or drowsiness in some individuals. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. If you experience palpitations or increased heart rate, stop exercising and consult your doctor.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Choose whole grains over refined carbohydrates.
Limit processed and high-sugar foods.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, drowsiness, or restlessness, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. It is generally safe for office work, but if you experience side effects, inform your supervisor.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever persists beyond 3 days, if symptoms worsen, or if you experience any serious side effects such as yellowing of the skin or eyes, severe abdominal pain, or allergic reactions. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine, especially at high doses, can increase the risk of liver and kidney damage. It may also lead to dependence on caffeine. Regular monitoring of liver and kidney function may be required if used for extended periods. It is not recommended for chronic pain management without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help manage chronic pain through exercises and manual techniques.

Evidence: Well-established
Relaxation techniques

Mindfulness and meditation can reduce stress and tension headaches.

Evidence: Moderate
Hot/cold therapy

Applying heat or cold packs can relieve localized pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination, as fever may be a contraindication for certain vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and away from direct sunlight. If crossing time zones, adjust dosing times accordingly, but do not exceed the maximum daily dose. Check local customs regulations regarding carrying medications. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with tension headaches
She frequently experienced headaches due to work stress. Her doctor prescribed this medicine. She took one tablet when the headache started and found relief within 30 minutes. She was advised not to take more than 4 tablets a day and to avoid alcohol. She also started practicing relaxation techniques to reduce stress.
💡 Lesson: This medicine can provide quick relief for tension headaches, but it should be used short-term and combined with lifestyle modifications.
👤 A 50-year-old man with dental pain
He had a toothache and took this medicine as prescribed by his dentist. The pain subsided, but he also experienced mild nausea. He then started taking it with food, which helped. He was advised to see a dentist for the underlying cause.
💡 Lesson: Taking this medicine with food can reduce stomach upset. It is important to treat the underlying cause of pain, not just the symptoms.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It can be taken on an empty stomach, but taking it with food may reduce the risk of stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to take with other medications?

A: It can interact with certain medications like warfarin and other paracetamol-containing products. Always inform your doctor about all medications you are taking.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe to take with other pain relievers?

🔄 Substitutes for m cold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe and can be taken in any amount.
    Fact: Exceeding the recommended dose can cause severe liver damage. Always follow the prescribed dose.
  • Myth: This medicine can cure all types of pain.
    Fact: It is effective for mild to moderate pain but not for severe pain or pain from serious conditions. Consult a doctor for persistent pain.
  • Myth: Taking this medicine with alcohol is safe.
    Fact: Alcohol increases the risk of liver toxicity. Avoid alcohol while taking this medicine.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol + Caffeine tablets (various manufacturers)

Brand Alternatives

  • Dolopar CC Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Paracetamol + Caffeine)","composition":"Paracetamol + Caffeine","uses":"Mild to moderate pain, fever","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Paracetamol alone","composition":"Paracetamol","uses":"Mild to moderate pain, fever","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen + Paracetamol","uses":"Moderate pain, inflammation","onset":"30-60 minutes","duration":"6-8 hours"}]

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