GLX MR Plus 8 mg/8 mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash or blistering
- Persistent high fever
If experiencing severe symptoms, call emergency services immediately.
What is lorsumo 8mg/8mg tablet mr used for?
This medicine is a combination of Lornoxicam (an NSAID) and Thiocolchicoside (a muscle relaxant) used for short-term relief of acute musculoskeletal pain and muscle spasm. It is taken orally with food, usually once or twice daily, and should not be used for more than 7 days without medical advice.
- Generic Name: Lornoxicam (8mg) + Thiocolchicoside (8mg)
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lorsumo 8mg/8mg tablet mr के बारे में (Hindi Summary)
उपयोग: यह दवा लॉर्नोक्सिकैम और थायोकोलचिकोसाइड का संयोजन है, जिसका उपयोग तीव्र मस्कुलोस्केलेटल दर्द और मांसपेशियों की ऐंठन के अल्पकालिक उपचार के लिए किया जाता है। यह दर्द, सूजन और मांसपेशियों की अकड़न को कम करने में मदद करती है। इसे भोजन के साथ लेना चाहिए और डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी, गुर्दे या यकृत की समस्या शामिल हो सकती है। यदि आपको काला मल, उल्टी में खून, तेज पेट दर्द, सांस लेने में कठिनाई, या त्वचा या आंखों का पीला पड़ना दिखे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे हमेशा भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इसका सेवन न करें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें।
💊 lorsumo 8mg/8mg tablet mr Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"Relieves pain and reduces muscle spasm in conditions such as low back pain, neck pain, and myofascial pain syndrome.","evidence":"Well-established"},{"condition":"Post-traumatic pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling","description":"Reduces inflammation and pain following injuries such as sprains, strains, and contusions.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain and muscle spasm after surgical procedures.","evidence":"Moderate"},{"condition":"Osteoarthritis flare-up","description":"Provides symptomatic relief of pain and stiffness during acute exacerbations of osteoarthritis.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes prescribed off-label for tension headaches associated with muscle spasm.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"May be used off-label for short-term relief of muscle pain in fibromyalgia, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Post-traumatic pain, Post-operative pain, Osteoarthritis flare-up
📋 Drug Information
| Generic Name(s) | Lornoxicam (8mg) + Thiocolchicoside (8mg) |
| Brand Name | lorsumo 8mg/8mg tablet mr |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Lornoxicam is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased production of prostaglandins, which are mediators of pain, inflammation, and fever. Thiocolchicoside is a centrally acting muscle relaxant that acts as a GABA-A receptor agonist, enhancing inhibitory neurotransmission in the spinal cord and brainstem, thereby reducing muscle spasm and stiffness. Together, they provide both anti-inflammatory and muscle relaxant effects.
Mechanism Steps
💡 How to Take lorsumo 8mg/8mg tablet mr
Strength: Tablet containing Lornoxicam 8 mg and Thiocolchicoside 8 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, preferably with food. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Not recommended in severe renal impairment. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Not recommended in severe hepatic impairment. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose is generally two tablets (16 mg Lornoxicam and 16 mg Thiocolchicoside) per day, but this must be confirmed by a qualified clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lorsumo 8mg/8mg tablet mr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors/ARBs | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Beta-blockers | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, diclofenac)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics
- SSRIs
- Beta-blockers
- Cyclosporine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulcers, and drowsiness. It may also worsen liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Lornoxicam, Thiocolchicoside, or any component of the formulation","History of gastrointestinal bleeding or peptic ulcer disease","Severe liver impairment","Severe kidney impairment","Heart failure (severe)","Third trimester of pregnancy","Breastfeeding","Children and adolescents under 18 years (safety not established)","Active bleeding disorders"]
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of gastrointestinal bleeding, especially with long-term use.","Inform your doctor if you have a history of kidney or liver disease, heart failure, or hypertension.","Do not use for longer than prescribed without medical advice.","Avoid concurrent use with other NSAIDs.","Consult your doctor before taking any other medication, including over-the-counter drugs and herbal supplements."]
🤱 Lactation Safety
Not established from the available information. It is not known whether Lornoxicam or Thiocolchicoside are excreted in human breast milk. Breastfeeding is not recommended while taking this medicine unless clearly advised by a doctor.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, dizziness, and kidney or liver damage. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs, renal and hepatic function, and manage complications accordingly.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or bleeding disorders. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at a higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events when taking NSAIDs like Lornoxicam. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use with other NSAIDs or anticoagulants unless clearly necessary.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like Lornoxicam may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Discuss safer alternatives for pain management with your doctor.
🏥 Post-Surgery Considerations
This medicine may be prescribed for short-term pain management after surgery. However, it should be used with caution due to the risk of bleeding and kidney impairment. Follow your surgeon's instructions carefully and do not exceed the recommended dose or duration.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop the medicine temporarily before certain procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or activities that could worsen your condition. Gentle stretching and low-impact exercises may be beneficial, but consult your doctor or physiotherapist before starting any exercise program. Stop immediately if you experience increased pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest and avoid strenuous activities while recovering from acute musculoskeletal pain. Inform your employer if your work involves heavy lifting or operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as black stools, vomiting blood, severe abdominal pain, allergic reactions, or signs of liver or kidney problems. Do not stop taking this medicine abruptly if you have been on it for a longer duration without consulting your doctor. Usually, this medicine is prescribed for short-term use, and your doctor will advise you when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the increased risk of serious side effects such as gastrointestinal bleeding, ulcers, kidney impairment, liver toxicity, and cardiovascular events. If long-term use is necessary, regular monitoring of liver and kidney function, blood counts, and gastrointestinal symptoms is essential. Consult your doctor regularly to assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength and flexibility.
Evidence: Well-establishedApplying heat or cold packs can help reduce muscle spasm and pain.
Evidence: ModerateMay provide relief for certain types of musculoskeletal pain.
Evidence: LimitedCreams or gels containing NSAIDs or capsaicin can provide localized pain relief.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive any vaccine, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations regarding prescription medicines before traveling internationally. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it with food. However, the full effect may take a few hours.
A: No, it is recommended to take this medicine with food or milk to reduce the risk of stomach upset and gastrointestinal bleeding.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.
A: Inform your doctor about all medications you are taking, as this medicine can interact with several drugs, including blood thinners, other NSAIDs, and certain antidepressants.
🤔 Common Patient Concerns
🔄 Substitutes for lorsumo 8mg/8mg tablet mr
View AllAlternative brands with exact same active ingredient:
-
lornoxi t tabletHetero Drugs Ltd ₹38.10 81.1% CHEAPER
-
zenlong t 8 mg/8 mg tabletKhandelwal Laboratories Pvt Ltd ₹190.00 5.9% CHEAPER
-
Flexispaz 8 mg/8 mg CapsuleGlenmark Pharmaceuticals Ltd ₹203.50 0.8% COSTLIER
-
glx mr plus 8 mg/8 mg tabletGufic Bioscience Ltd ₹252.55 25.1% COSTLIER
-
laxmo t 8mg/8mg tabletAsterisk Laboratories India Pvt Ltd ₹281.25 39.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects such as gastrointestinal bleeding, kidney problems, and liver toxicity. - Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking this medicine on an empty stomach increases the risk of stomach upset and gastrointestinal bleeding. Always take it with food or milk. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is generally avoided during pregnancy, especially in the third trimester, due to potential risks to the fetus. Consult your doctor for safer alternatives. - Myth: You can stop this medicine abruptly without any issues.
Fact: This medicine is usually taken for a short duration. If you have been taking it for a longer period, consult your doctor before stopping to avoid any withdrawal effects or rebound pain.
🔄 Alternative Options
Generic Alternatives
- Lornoxicam + Thiocolchicoside combination