Longifene Syrup (Buclizine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (rash, itching, swelling, difficulty breathing)
- Irregular heartbeat or palpitations
- Confusion, hallucinations, or seizures
- Severe drowsiness or difficulty staying awake
- Yellowing of skin or eyes (jaundice)
- Decreased urine output
- Persistent vomiting or inability to keep fluids down
If experiencing severe symptoms, call emergency services immediately.
What is longimax 6mg syrup used for?
This medicine is an antihistamine syrup containing buclizine, used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vertigo. It works by blocking histamine receptors in the brain.
- Generic Name: Buclizine (6mg/5ml)
- Manufacturer: Lemford Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 longimax 6mg syrup के बारे में (Hindi Summary)
उपयोग: यह दवा बुक्लिज़ीन नामक एंटीहिस्टामिन का सिरप है, जिसका उपयोग मोशन सिकनेस (यात्रा के दौरान उल्टी और चक्कर) और वर्टिगो (चक्कर आना) के इलाज में किया जाता है। यह मतली, उल्टी और चक्कर को कम करने में मदद करती है। यह दवा दिमाग में हिस्टामिन रिसेप्टर्स को ब्लॉक करके काम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, धुंधली दृष्टि और चक्कर आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको एलर्जी, दिल की धड़कन अनियमित, भ्रम या मतिभ्रम का अनुभव हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा नींद ला सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और बढ़ सकती है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। बच्चों को डॉक्टर की सलाह के बिना न दें। निर्धारित खुराक से अधिक न लें।
💊 longimax 6mg syrup Uses & Benefits
[{"condition":"Motion sickness","description":"Prevents and treats nausea, vomiting, and dizziness associated with travel.","evidence":"Well-established"},{"condition":"Vertigo","description":"Helps relieve dizziness and spinning sensation due to vestibular disorders.","evidence":"Moderate"},{"condition":"Nausea and vomiting","description":"Used to control nausea and vomiting from various causes.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine-associated nausea","description":"Sometimes prescribed to relieve nausea during migraine attacks.","evidence":"Limited"},{"condition":"Anxiety","description":"Occasionally used for its sedative effects in anxiety, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Motion sickness
Also treats: Vertigo, Nausea and vomiting
📋 Drug Information
| Generic Name(s) | Buclizine (6mg/5ml) |
| Brand Name | longimax 6mg syrup |
| Manufacturer | Lemford Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | H1 Antihistaminics (First Generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Buclizine is a piperazine antihistamine that competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. By blocking H1 receptors in the brain, it reduces vestibular stimulation and inhibits the chemoreceptor trigger zone, thereby alleviating nausea and vomiting. It also possesses anticholinergic properties that contribute to its antiemetic and sedative effects.
Mechanism Steps
💡 How to Take longimax 6mg syrup
Strength: Buclizine 6mg/5ml syrup
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 25-50 mg (as buclizine hydrochloride) taken 30-60 minutes before travel or as directed by a physician. For vertigo, the dose may be 25 mg two to three times daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Not established from the available information. Use with caution in patients with renal impairment. Consult a doctor for dose adjustment. |
| Hepatic Impairment | Not established from the available information. Use with caution in patients with hepatic impairment. Consult a doctor for dose adjustment. |
| Maximum Daily Dose | Not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of longimax 6mg syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Opioids | Major | |
| MAO inhibitors | Major | |
| Tricyclic antidepressants | Moderate | |
| Metoclopramide | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, opioids, benzodiazepines)
- MAO inhibitors
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- Metoclopramide
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness and impair motor skills. Combining alcohol with buclizine may also enhance CNS depression, leading to excessive sedation, respiratory depression, and impaired judgment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to buclizine or any component of the formulation","Premature infants and neonates","Patients with glaucoma","Patients with prostatic hypertrophy or urinary retention","Patients with severe liver disease"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Use with caution in patients with asthma, COPD, or sleep apnea.","May cause dry mouth, constipation, and urinary retention.","Do not exceed recommended dose.","Consult doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Not established from the available information. It is not known whether buclizine is excreted in human milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, confusion, hallucinations, seizures, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
This medicine can cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Do not consume alcohol while taking this medicine as it can increase drowsiness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not exceed the recommended dose. Keep out of reach of children. If symptoms persist or worsen, consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. They may experience increased drowsiness, confusion, dry mouth, and urinary retention. Use with caution and start with a lower dose. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of buclizine during pregnancy is not well established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist if you are taking this medicine. It may need to be stopped before surgery as advised by your doctor.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental problems. Inform your dentist if you are taking this medicine. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may impair your ability to exercise safely. Avoid activities that require balance or coordination until you know how the medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires such activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you have been taking it regularly. If you experience severe side effects or your symptoms worsen, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects such as sedation, dry mouth, and urinary retention. Regular monitoring by a doctor is advised if long-term therapy is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help reduce motion sickness without medication.
Evidence: LimitedNatural remedy for nausea, may complement or serve as an alternative.
Evidence: ModerateFor vertigo, vestibular rehabilitation exercises can be effective.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions between this medicine and vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid customs issues. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep the bottle tightly closed and upright to prevent leakage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 30-60 minutes after oral administration. For motion sickness, it is best taken 30-60 minutes before travel.
A: It may interact with certain medications such as CNS depressants, MAO inhibitors, and anticholinergics. Always inform your doctor about all medicines you are taking.
A: Pediatric dosing is not established from available information. Consult a pediatrician before giving this medicine to children.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for longimax 6mg syrup
View AllAlternative brands with exact same active ingredient:
-
buc syrupS.S.M Pharmaceuticals ₹52.28 20.3% CHEAPER
-
longifene syrupMankind Pharma Ltd ₹141.79 116% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of nausea.
Fact: This medicine is specifically effective for motion sickness and vertigo-related nausea. It may not be effective for nausea due to other causes. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol increases the sedative effects of this medicine and should be avoided. - Myth: This medicine is safe for infants.
Fact: This medicine is contraindicated in premature infants and neonates. Consult a pediatrician for young children.
🔄 Alternative Options
Generic Alternatives
- Buclizine hydrochloride syrup
Brand Alternatives
- Longifene syrup