lamrest 5 tablet - Melatonin (5mg) medicine

Lamrest 5 Tablet: Complete Guide To Uses, Side Effects, And Safety

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🏭 Tas Med India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 11, 2026
🤰 Pregnancy Category Not established from the available information. Melatonin is not recommended during pregnancy unless advised by a doctor. Consult your healthcare provider. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for sleep disorders.
Dr. Ravishankar Kumar
Medically Reviewed by Dr. Ravishankar Kumar ✓ Verified Doctor
B.A.M.S. (RMLAU Ayodhya) • Ex-Balrampur Hospital, Lucknow
Dr. Ravishankar Kumar
Clinically Verified by Dr. Ravishankar Kumar (B.A.M.S., RMLAU) — View Medical Verification Profile ↗
Clinical Background: Balrampur Hospital, Lucknow (Emergency Medicine) & SCPM Hospital | Standards: CDSCO, Indian Pharmacopoeia (IP) & WHO

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing.
  • Confusion or disorientation.
  • Extreme drowsiness or difficulty waking up.
  • Mood changes, depression, or suicidal thoughts.
  • Palpitations or irregular heartbeat.
  • Severe headache that does not go away.
  • Signs of liver problems: yellowing of skin or eyes, dark urine, abdominal pain.

If experiencing severe symptoms, call emergency services immediately.

What is lamrest 5 tablet used for?

This medicine contains melatonin 5 mg, a hormone that helps regulate your sleep-wake cycle. It is used to treat insomnia, jet lag, and shift work sleep disorder. Take it 30-60 minutes before bedtime. Avoid alcohol and driving after taking it.

  • Generic Name: Melatonin (5mg)
  • Manufacturer: Tas Med India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lamrest 5 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मेलाटोनिन 5 मिलीग्राम की गोली है, जिसका उपयोग नींद न आने की समस्या (अनिद्रा), जेट लैग और शिफ्ट वर्क स्लीप डिसऑर्डर के इलाज के लिए किया जाता है। यह शरीर की प्राकृतिक नींद-जागने की चक्र को नियमित करने में मदद करती है। इसे सोने से 30-60 मिनट पहले लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, मतली, नींद आना और दिन में सुस्ती शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको एलर्जी, सांस लेने में कठिनाई, या मानसिक भ्रम महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसकी खुराक से अधिक न लें। दवा लेने के बाद 4-5 घंटे तक वाहन न चलाएं या मशीनरी न चलाएं, क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

lamrest 5 tablet Uses & Benefits

Insomnia Well-established

Helps reduce the time it takes to fall asleep and improves overall sleep quality in people with difficulty initiating sleep.

Jet lag Well-established

Helps reset the body's internal clock when travelling across multiple time zones, reducing daytime fatigue and improving sleep at the destination.

Shift work sleep disorder Moderate

May help night-shift workers adjust their sleep schedule and improve daytime sleep quality.

Delayed sleep phase syndrome Moderate

Used to advance sleep timing in people who habitually go to sleep very late and have difficulty waking up in the morning.

Off-Label & Investigational Uses:

Anxiety before surgery Limited (Off-label)

Sometimes used to reduce preoperative anxiety and improve sleep the night before surgery.

Migraine prophylaxis Limited (Off-label)

May be prescribed off-label to reduce the frequency of migraines in some patients.

Tinnitus Insufficient (Off-label)

Occasionally used to help with sleep disturbances associated with tinnitus.

Primary Treatment for: Insomnia
Also Treats:
Jet lag Shift work sleep disorder Delayed sleep phase syndrome

📋 Drug Information

Generic Name(s)Melatonin (5mg)
Brand Namelamrest 5 tablet
ManufacturerTas Med India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTHERS
Action ClassMelatonin agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine 30-60 minutes before your planned bedtime.
2
Maintain a consistent sleep schedule by going to bed and waking up at the same time daily.
3
Avoid screens and bright lights for at least an hour before bedtime.
4
Do not take this medicine with alcohol or other sedatives.
5
If you don't see improvement in sleep after 7-10 days, consult your doctor.
6
Do not drive or operate machinery for at least 4-5 hours after taking this medicine.
7
Keep a sleep diary to track your sleep patterns and share with your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Difficulty falling asleep
This medicine is commonly prescribed for this.
Likely Use
✅
Jet lag
This medicine helps reset the sleep-wake cycle.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Anxiety
This medicine is not a primary treatment for anxiety.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMelatonin is rapidly absorbed from the gastrointestinal tract after oral administration. However, it undergoes extensive first-pass metabolism, which reduces its bioavailability.
DistributionMelatonin is widely distributed throughout the body, including the brain, and can cross the blood-brain barrier and placenta. It is also found in breast milk.
Protein BindingApproximately 60% of melatonin is bound to plasma proteins.
MetabolismMelatonin is primarily metabolized in the liver by cytochrome P450 enzymes, mainly CYP1A2 and to a lesser extent CYP2C19. The major metabolite is 6-hydroxymelatonin, which is further conjugated with sulfate or glucuronic acid.
Half-LifeThe elimination half-life of melatonin is approximately 30 to 50 minutes.
ExcretionMelatonin and its metabolites are excreted primarily in the urine. About 80% of the administered dose is excreted in urine as 6-sulfatoxymelatonin.
BioavailabilityThe oral bioavailability of melatonin is approximately 15% due to extensive first-pass metabolism. It varies widely among individuals.
Onset of ActionThis medicine typically starts working within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 2 hours after oral administration.
Duration of ActionThe effects of this medicine last for approximately 4 to 6 hours.

How It Works

This medicine contains melatonin, which is a synthetic version of the natural hormone produced by the pineal gland. Melatonin works by binding to melatonin receptors (MT1 and MT2) in the brain, particularly in the suprachiasmatic nucleus of the hypothalamus, which is the master clock that controls circadian rhythms. Activation of these receptors helps regulate the timing of sleep and wakefulness, promoting sleep onset and adjusting the body's internal clock.

Mechanism Steps

1
Binding to melatonin receptors: Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus of the brain.
2
Inhibition of neuronal firing: Activation of MT1 receptors inhibits neuronal firing in the suprachiasmatic nucleus, reducing alertness.
3
Phase shifting of circadian rhythm: Activation of MT2 receptors helps shift the timing of the circadian clock, promoting sleep at the desired time.
4
Promotion of sleep: The overall effect is a reduction in sleep onset latency and an increase in total sleep time.

💡 How to Take lamrest 5 tablet

Strength: Melatonin 5 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2Take it 30 to 60 minutes before your planned bedtime.
3Do not crush or chew the tablet; swallow it whole.
4Take it at the same time each night for best results.
5Avoid taking it with a heavy meal, as it may delay absorption.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 mg taken orally once daily, 30 to 60 minutes before bedtime. However, the dose may vary depending on the indication, age, and individual response. For jet lag, it is often taken at the destination bedtime for a few days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose (e.g., 1-2 mg) and adjust as needed under medical supervision. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution in severe kidney disease. Consult your doctor.
Hepatic ImpairmentIn patients with liver impairment, melatonin clearance may be reduced. Use with caution and consult your doctor for dose adjustment.
Maximum Daily DoseThe maximum recommended daily dose is 5 mg, but higher doses may be prescribed by a doctor in specific cases. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take on an empty stomach or with a light snack
Food may delay the onset of action.
Caffeine
Avoid in the evening
Caffeine can counteract the sleep-inducing effects.
Alcohol
Avoid
Increases drowsiness and disrupts sleep.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of lamrest 5 tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Nausea (Common (5-10%))
Take with a light snack if it bothers you. Consult doctor if it continues.
Drowsiness (Common (5-10%))
This is expected. Avoid activities requiring alertness. If excessive, consult your doctor.
Daytime sleepiness (Common (5-10%))
Adjust the timing of the dose as advised by your doctor. Do not increase the dose.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Confusion (Rare (<0.1%))
Contact your doctor immediately if you feel confused or disoriented.
Mood changes (Rare (<0.1%))
Report any unusual mood swings, depression, or irritability to your doctor.

⚠️ Rare Side Effects

Vivid dreams or nightmares
Discuss with your doctor if it disturbs your sleep.
Abdominal pain
Usually temporary. Consult doctor if severe or persistent.
Palpitations
Seek medical advice if you experience a racing or pounding heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Fluvoxamine Major
Warfarin Major
Benzodiazepines Major
Oral contraceptives Moderate
Propranolol Moderate
Caffeine Moderate
Alcohol Moderate
Rifampicin Minor

🚨 Major Interactions

  • Fluvoxamine
  • Warfarin
  • CNS depressants (e.g., benzodiazepines, opioids)

⚡ Moderate Interactions

  • Oral contraceptives
  • Beta-blockers (e.g., propranolol)
  • Caffeine

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, impair coordination, and worsen sleep quality. It may also increase the risk of falls and accidents.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to melatonin or any component of this medicine","Severe liver impairment","Severe kidney impairment","Pregnancy and breastfeeding (unless advised by a doctor)","Children under 18 years (unless prescribed by a doctor)"]

⚠️ Warnings & Precautions

["Do not drive or operate heavy machinery for at least 4-5 hours after taking this medicine.","Avoid alcohol while taking this medicine.","Inform your doctor if you have liver or kidney disease.","Inform your doctor if you are taking any other medications, especially blood thinners, antidepressants, or sedatives.","Do not take more than the prescribed dose.","If you experience any allergic reaction, stop the medicine and seek immediate medical help.","Use with caution in elderly patients due to increased risk of falls."]

🤱 Lactation Safety

Melatonin is excreted in breast milk. It is not recommended during breastfeeding unless advised by a doctor. Consult your healthcare provider.

💊 Overdose Management

Overdose of this medicine may cause excessive drowsiness, dizziness, headache, nausea, and disorientation. If you suspect an overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember if it is still close to your usual bedtime. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Avoid driving or operating heavy machinery for at least 4-5 hours after taking this medicine, as it may cause drowsiness. Do not consume alcohol while taking this medicine, as it can increase drowsiness and impair your ability to sleep well. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, including drowsiness and dizziness. Start with a lower dose and use with caution to prevent falls. Consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Melatonin is not recommended during pregnancy unless specifically advised by a healthcare provider.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery, as it may interact with anesthesia and other medications. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause drowsiness and interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a consistent sleep schedule by going to bed and waking up at the same time daily.
🥗
Create a relaxing bedtime routine, such as reading or taking a warm bath.
😴
Avoid screens and bright lights for at least an hour before bedtime.
💧
Limit caffeine and alcohol intake, especially in the evening.
🧘
Exercise regularly, but avoid vigorous activity close to bedtime.
🌞
Keep your bedroom dark, quiet, and cool for optimal sleep.

🏋️ Exercise Considerations

This medicine may cause drowsiness. Avoid exercising immediately after taking it, as it may increase the risk of falls or injuries. Exercise earlier in the day is generally safe.

🥗 Diet Recommendations

Include foods rich in tryptophan, such as turkey, milk, and bananas, which may promote sleep.
Avoid heavy meals close to bedtime.
Stay hydrated throughout the day, but reduce fluid intake before bed to prevent night-time awakenings.
Limit caffeine and alcohol, especially in the evening.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to take it when you can get a full night's sleep. If you work night shifts, adjust the timing as advised by your doctor. Avoid taking it if you need to be alert shortly after.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience any serious side effects, if your sleep does not improve after 7-10 days, or if you develop new symptoms. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is generally considered safe for most people, but its effects beyond a few months are not well-studied. Some people may experience reduced effectiveness over time. It is advisable to use it for the shortest duration necessary and under medical supervision. Regular follow-up with your doctor is recommended to assess ongoing need and monitor for any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive Behavioral Therapy for Insomnia (CBT-I)

A structured program to change sleep habits and thoughts that affect sleep.

Evidence: Well-established
Sleep hygiene education

Practices and habits that promote consistent, uninterrupted sleep.

Evidence: Well-established
Relaxation techniques

Techniques such as deep breathing, meditation, and progressive muscle relaxation.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. For jet lag, take it at the destination bedtime for a few days. Store it in a cool, dry place away from direct sunlight. Check customs regulations for bringing melatonin into your destination country, as it may be regulated.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old software engineer working night shifts
Ravi struggled with sleep during the day due to his night shift schedule. His doctor prescribed this medicine 5 mg before his daytime sleep. Within a week, he was able to fall asleep faster and felt more refreshed. He made sure to take it at the same time every day and avoided caffeine before sleep.
💡 Lesson: Consistent timing and good sleep hygiene are key to getting the most benefit from this medicine.
👤 A 50-year-old woman with chronic insomnia
Mrs. Sharma had difficulty falling asleep for years. She was prescribed this medicine 5 mg at bedtime. She noticed improvement in sleep onset but experienced mild daytime drowsiness initially. Her doctor advised her to take it earlier in the evening and avoid driving. After two weeks, the drowsiness subsided, and her sleep improved significantly.
💡 Lesson: Mild side effects often diminish with continued use. Adjusting the timing can help manage daytime drowsiness.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 30 to 60 minutes after taking it.

Q: Can I take it every night?

A: It is generally recommended for short-term use. Consult your doctor if you need it for more than a few weeks.

Q: Is it safe to take with other medications?

A: Inform your doctor about all medications you are taking, as melatonin can interact with blood thinners, antidepressants, and sedatives.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember if it's still close to bedtime. If it's almost time for your next dose, skip it and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe to take with other sleep aids?

🔄 Substitutes for lamrest 5 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Melatonin is a sleeping pill that knocks you out.
    Fact: Melatonin is not a sedative; it helps regulate your sleep-wake cycle and signals your body that it's time to sleep.
  • Myth: Melatonin is addictive.
    Fact: Melatonin is not known to cause dependence or addiction like benzodiazepines.
  • Myth: You can take melatonin anytime you want to sleep.
    Fact: Melatonin works best when taken at the same time each night, 30-60 minutes before bedtime, to reset your circadian rhythm.

🔄 Alternative Options

Generic Alternatives

  • Melatonin 5 mg tablets

Brand Alternatives

  • Meloset 5 mg tablet
  • Zolfresh 5 mg tablet
  • Melatonin 5 mg tablet (various brands)

📊 Comparison with Similar Medicines

MedicineActive IngredientRelease TypePrimary Use
Lamrest 5 tabletMelatonin 5 mgImmediate releaseInsomnia, jet lag
Meloset 5 tabletMelatonin 5 mgImmediate releaseInsomnia, jet lag
Zolfresh 5 tabletMelatonin 5 mgImmediate releaseInsomnia, jet lag

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