asklerol 3% injection - Polidocanol (30mg) medicine

asklerol 3% injection

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🏭 Samarth Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
🤰 Pregnancy Category A 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is asklerol 3% injection used for?

This medicine contains Polidocanol (30mg) and is used to treat OTHERS. Sclerosant that damages endothelial cells, leading to thrombosis and fibrosis of the vein.. Always consult your doctor before use.

  • Generic Name: Polidocanol
  • Manufacturer: Samarth Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 asklerol 3% injection Uses & Benefits

Treatment of varicose veins and telangiectasias.

Off-label uses: Hemorrhoids, Esophageal varices, Vascular malformations

📋 Drug Information

Generic Name(s)Polidocanol
Brand NameAsklerol 3% Injection
ManufacturerSamarth Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTHERS
Action ClassSclerosing agent-Varicose Vein
Route of AdministrationIntravenous (local injection into the vein)
StorageStore at room temperature (20-25°C), protect from light.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot applicable; administered directly into the vein via injection.
DistributionDistributes into the vascular wall and surrounding tissues.
Protein BindingNot well characterized; likely low.
MetabolismMetabolized by esterases in plasma and liver.
Half-LifeApproximately 1-2 hours.
ExcretionPrimarily renal excretion of metabolites.
Bioavailability100% (intravenous administration).
Onset of ActionImmediate upon injection.
Peak Plasma TimeNot applicable; local effect.
Duration of ActionVariable; depends on vessel size and dose.

How It Works

Sclerosant that damages endothelial cells, leading to thrombosis and fibrosis of the vein.

Mechanism Steps

1Injection into the vein lumen.
2Damage to endothelial cells due to detergent effect.
3Exposure of subendothelial collagen.
4Platelet aggregation and thrombus formation.
5Inflammatory response and fibrosis.
6Obliteration of the vein lumen.

💡 How to Take asklerol 3% injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of asklerol 3% injection

✅ Common Side Effects

Pain at injection site
Bruising
Swelling
Itching

🚨 Serious Side Effects

Deep vein thrombosis
Pulmonary embolism
Allergic reaction
Skin necrosis

⚠️ Rare Side Effects

Anaphylaxis
Arterial embolism
Nerve damage

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Heparin Major Increased bleeding risk
Antiplatelet agents Major Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Corticosteroids Moderate May reduce efficacy
Hormonal contraceptives Moderate Increased risk of thromboembolism
Antihistamines Minor Possible reduced efficacy
Alcohol Minor Increased bleeding risk

🚨 Major Interactions

  • Warfarin
  • Heparin
  • Antiplatelet agents

⚡ Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Hormonal contraceptives

🍷 Alcohol Interaction

May increase risk of bleeding; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to polidocanol, acute thromboembolic disease, severe arterial insufficiency, infected or ulcerated varicose veins.

🤱 Lactation Safety

Not recommended; excretion in breast milk unknown.

💊 Overdose Management

Supportive care; monitor for bleeding, thrombosis, or allergic reactions.

⏰ Missed Dose

Not applicable; administered by healthcare professional.

🔄 Substitutes for asklerol 3% injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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