Adikold Plus Oral Suspension: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat.
- Yellowing of the skin or eyes (jaundice).
- Severe abdominal pain or vomiting blood.
- Blood in stool or black, tarry stools.
- Seizures or severe confusion.
- Irregular heartbeat or palpitations.
- Decreased urine output or inability to urinate.
- High fever that does not respond to treatment.
If experiencing severe symptoms, call emergency services immediately.
What is kynicold plus oral suspension used for?
This medicine is a combination of chlorpheniramine maleate (an antihistamine) and paracetamol (a pain reliever and fever reducer) used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever. It is available as an oral suspension and should be taken as directed by a doctor.
- Generic Name: Chlorpheniramine Maleate (2mg/5ml) + Paracetamol (250mg/5ml)
- Manufacturer: Kyna Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kynicold plus oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा आम सर्दी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में पानी आना, नाक या गले में खुजली, हल्का बुखार और शरीर में दर्द से राहत दिलाने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल दो सक्रिय तत्व हैं। यह दवा 2 साल से बड़े बच्चों और वयस्कों के लिए है, लेकिन डोज डॉक्टर द्वारा तय की जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सूजन, सांस लेने में कठिनाई, या लीवर की समस्या हो सकती है। अगर कोई भी दुष्प्रभाव लंबे समय तक रहे तो डॉक्टर से सलाह लें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको लीवर या किडनी की बीमारी, अस्थमा, ग्लूकोमा, पेशाब करने में कठिनाई, या कोई अन्य चिकित्सीय स्थिति है। निर्धारित खुराक से अधिक न लें। इस दवा के साथ शराब और अन्य नींद लाने वाली दवाओं से बचें। बिना डॉक्टर की सलाह के लंबे समय तक इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 kynicold plus oral suspension Uses & Benefits
[{"condition":"Common cold","description":"Relieves runny nose, sneezing, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, rhinorrhea, and itching of the nose and throat due to allergies.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Helps alleviate watery, itchy eyes caused by allergic reactions.","evidence":"Moderate"},{"condition":"Mild pain and fever","description":"Paracetamol component provides relief from mild to moderate pain and reduces fever.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects, but not recommended due to risk of dependence and side effects.","evidence":"Limited"},{"condition":"Motion sickness","description":"Chlorpheniramine may be used off-label to prevent motion sickness, but other agents are preferred.","evidence":"Limited"}]
Primary treatment for: Common cold and allergic rhinitis
Also treats: Allergic conjunctivitis, Mild pain and fever
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate (2mg/5ml) + Paracetamol (250mg/5ml) |
| Brand Name | kynicold plus oral suspension |
| Manufacturer | Kyna Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, protected from light. Do not freeze. Keep the bottle tightly closed. Shake well before each use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. It also possesses anticholinergic properties, which contribute to drying of secretions and sedation. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to reduction of fever and pain. The exact mechanism of paracetamol is not fully understood, but it is believed to involve inhibition of cyclooxygenase enzymes in the brain and spinal cord.
Mechanism Steps
💡 How to Take kynicold plus oral suspension
Strength: Each 5 mL of oral suspension contains Chlorpheniramine Maleate 2 mg and Paracetamol 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mL (2 teaspoons) every 4 to 6 hours as needed for symptoms, not to exceed 6 doses in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Use the measuring cup provided with the product for accurate dosing. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. This medicine is not recommended for children under 2 years of age. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of chlorpheniramine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Paracetamol dose should be reduced or avoided in severe liver disease. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | For adults: Maximum of 6 doses (60 mL) in 24 hours. Do not exceed 4 grams of paracetamol per day from all sources. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kynicold plus oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Warfarin | Major | |
| Anticholinergics | Moderate | |
| SSRIs | Moderate | |
| Carbamazepine | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol and other CNS depressants
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, benztropine)
- Selective serotonin reuptake inhibitors (SSRIs)
- Carbamazepine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of liver damage from paracetamol. Concurrent use may also impair judgment and coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, paracetamol, or any component of the formulation.","Severe liver disease or severe active liver disease.","Severe kidney impairment.","Patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI.","Children under 2 years of age (due to risk of serious adverse effects).","Narrow-angle glaucoma.","Urinary retention due to prostatic hypertrophy.","Severe cardiovascular disease."]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how this medicine affects you.","Avoid alcohol and other CNS depressants.","Do not exceed the recommended dose of paracetamol; high doses can cause liver damage.","Use with caution in patients with liver or kidney disease, asthma, glaucoma, or difficulty urinating.","May cause paradoxical excitation in children.","Elderly patients are more susceptible to anticholinergic effects and drowsiness.","Do not use for longer than directed without consulting a doctor.","Consult a doctor if symptoms persist or worsen."]
🤱 Lactation Safety
Chlorpheniramine and paracetamol are excreted in breast milk in small amounts. This medicine should be used with caution during breastfeeding, as chlorpheniramine may cause drowsiness in the infant. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and severe anticholinergic effects due to chlorpheniramine. Symptoms of paracetamol overdose include nausea, vomiting, abdominal pain, and liver failure. Symptoms of chlorpheniramine overdose include drowsiness, confusion, seizures, and respiratory depression. If overdose is suspected, seek immediate medical attention. Treatment includes activated charcoal, acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have liver or kidney disease, asthma, glaucoma, difficulty urinating due to an enlarged prostate, or any other medical condition. Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. Do not use this medicine for longer than directed without consulting a doctor. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not use this medicine if the seal is broken or if the suspension appears discolored. Store at room temperature and protect from light. Do not freeze.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of chlorpheniramine, including drowsiness, dizziness, confusion, and anticholinergic effects such as dry mouth, constipation, and urinary retention. They may also be at higher risk of liver toxicity from paracetamol. Use with caution and consider lower doses. Regular monitoring of liver and kidney function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination in pregnancy is not well established. Paracetamol is generally considered safe when used at recommended doses, but chlorpheniramine may pose risks. Discuss alternative treatments with your doctor.
🏥 Post-Surgery Considerations
After surgery, consult your doctor before taking this medicine. Chlorpheniramine may interact with anesthetics and other medications used during surgery, and paracetamol may mask fever that could indicate an infection. Your doctor will determine if it is safe to use.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. Chlorpheniramine can cause dry mouth, which may increase the risk of dental problems. Paracetamol may interact with other pain medications used during dental work. Your dentist may adjust your treatment plan accordingly.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may impair your ability to exercise safely. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. If you exercise, do so with caution and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks that require mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about timing the dose or alternative treatments.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 5-7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of chlorpheniramine may lead to tolerance, dependence, and anticholinergic effects. Chronic use of paracetamol at high doses can cause liver damage. Regular monitoring of liver and kidney function may be required if used for extended periods. Consult your doctor if you need to use this medicine for more than a few days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve nasal congestion without medication.
Evidence: Well-establishedFor allergic conjunctivitis, may provide targeted relief.
Evidence: ModerateCan help loosen mucus and relieve congestion.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider if you are taking this medicine, especially if you have a fever. Vaccination may be postponed if you have a moderate or severe illness with fever.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before use
❌ DON'T
Do not use if the suspension appears discolored
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue taking the medicine as prescribed, but adjust the timing gradually. Do not leave it in a hot car or checked luggage. If you are traveling for an extended period, ensure you have enough supply and consult your doctor for a refill.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to relieve symptoms within 30-60 minutes after taking a dose.
A: It is generally recommended to take this medicine with food or milk to reduce the risk of stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. The safety of this combination in pregnancy is not well established.
A: Inform your doctor about all medications you are taking, as this medicine can interact with several drugs, including MAOIs, alcohol, and warfarin.
🤔 Common Patient Concerns
🔄 Substitutes for kynicold plus oral suspension
View AllAlternative brands with exact same active ingredient:
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dencold oral suspensionBMW Pharmaco India Pvt. Ltd. ₹25.31 47.3% CHEAPER
-
ezinoz oral suspensionDR Best pharmaceuticals Pvt Ltd ₹26.25 45.3% CHEAPER
-
coldova-ds syrupNectar Biopharma Pvt Limited ₹30.00 37.5% CHEAPER
-
exhale p suspensionIndian Pharmaceuticals ₹30.84 35.8% CHEAPER
-
vista cold suspensionInnova Formulations Pvt Ltd ₹35.00 27.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take this medicine with other paracetamol-containing products.
Fact: Taking multiple paracetamol-containing products can lead to overdose and liver damage. - Myth: This medicine is safe for children under 2 years.
Fact: This medicine is not recommended for children under 2 years due to risk of serious adverse effects.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine Maleate + Paracetamol oral suspension
Brand Alternatives
- Adikold Plus Oral Suspension