Anicold Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or yellowing of eyes/skin
- Difficulty breathing or swelling of face, lips, or throat
- Severe drowsiness, confusion, or seizures
- Decreased urine output or inability to urinate
- Persistent high fever unresponsive to treatment
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is coldova-ds syrup used for?
This medicine is a combination syrup containing chlorpheniramine maleate (an antihistamine) and paracetamol (a pain and fever reducer). It is used to relieve symptoms of common cold and allergies such as sneezing, runny nose, and mild fever. It should be taken as prescribed, usually every 4-6 hours, and should not exceed 4 doses in 24 hours.
- Generic Name: Chlorpheniramine Maleate + Paracetamol
- Manufacturer: Nectar Biopharma Pvt Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coldova-ds syrup के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल का संयोजन है, जिसका उपयोग सर्दी-जुकाम और एलर्जी के लक्षणों जैसे छींक आना, नाक बहना, आंखों में पानी आना, और हल्के बुखार या दर्द को कम करने के लिए किया जाता है। यह दवा डॉक्टर के परामर्श से ही लेनी चाहिए और निर्धारित मात्रा से अधिक नहीं लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, यकृत की क्षति, या रक्त विकार हो सकते हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब और अन्य नींद लाने वाली दवाओं से बचें। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। यकृत या गुर्दे की बीमारी, ग्लूकोमा, प्रोस्टेट की समस्या, या अस्थमा हो तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 coldova-ds syrup Uses & Benefits
[{"condition":"Common cold","description":"Relieves sneezing, runny nose, and mild fever associated with the common cold.","evidence":"Well-established for symptomatic relief"},{"condition":"Allergic rhinitis","description":"Reduces nasal itching, sneezing, and rhinorrhea due to seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps control itching and skin rash in mild allergic urticaria.","evidence":"Moderate"},{"condition":"Fever and mild pain","description":"Paracetamol component lowers fever and relieves headache, body ache, or sore throat.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insomnia due to allergy","description":"Sometimes used for its sedative effect in allergic patients with sleep disturbance.","evidence":"Limited"}]
Primary treatment for: Common cold and allergic rhinitis
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Paracetamol |
| Brand Name | Alex P Syrup |
| Manufacturer | Nectar Biopharma Pvt Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, and runny nose. It also crosses the blood-brain barrier and causes sedation by blocking central H1 receptors. Paracetamol acts mainly in the central nervous system by inhibiting prostaglandin synthesis, which lowers fever and reduces pain perception. The combination provides both antihistaminic and analgesic-antipyretic effects.
Mechanism Steps
💡 How to Take coldova-ds syrup
Strength: Each 5 ml contains Chlorpheniramine Maleate 2 mg and Paracetamol 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10 ml (2 teaspoons) every 4 to 6 hours as needed, not exceeding 4 doses in 24 hours. However, dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects of chlorpheniramine. Use with caution and consider lower doses. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Paracetamol dose should be reduced or avoided in severe liver disease. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | For adults: maximum 4 doses (40 ml) in 24 hours. Do not exceed 4 grams of paracetamol per day from all sources. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coldova-ds syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Warfarin | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Fluoxetine | Moderate | |
| Rifampicin | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol and other CNS depressants
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- CYP2D6 inhibitors (e.g., fluoxetine, quinidine)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it can intensify drowsiness, dizziness, and sedation caused by chlorpheniramine. Additionally, chronic alcohol use increases the risk of paracetamol-induced liver damage.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to chlorpheniramine, paracetamol, or any component","Severe liver disease or active liver failure","Use within 14 days of MAO inhibitor therapy","Newborns and premature infants","Narrow-angle glaucoma","Urinary retention due to prostatic hypertrophy"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Do not exceed recommended dose of paracetamol; risk of liver damage.","Use with caution in patients with glaucoma, prostatic hypertrophy, asthma, or thyroid disease.","Consult doctor before use in pregnancy or breastfeeding.","Do not use for more than 5 days without medical advice."]
🤱 Lactation Safety
Chlorpheniramine may pass into breast milk and cause drowsiness in the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose can cause severe liver damage from paracetamol and severe anticholinergic effects from chlorpheniramine. Symptoms include nausea, vomiting, abdominal pain, confusion, seizures, and coma. Seek emergency medical help immediately. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Avoid alcohol and other sedatives because they can increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have liver or kidney disease, glaucoma, enlarged prostate, asthma, or thyroid problems. Do not use other paracetamol-containing products at the same time to prevent overdose. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant or breastfeeding, consult your doctor before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine. They may also have reduced liver and kidney function, increasing the risk of side effects. Use with caution and consider lower doses under medical supervision.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Paracetamol is generally considered safe, but chlorpheniramine should be used with caution.
🏥 Post-Surgery Considerations
Consult your surgeon or anesthesiologist before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with anesthetics or sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine because it can cause drowsiness and dizziness. Light activities like walking are generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is best to avoid such activities until you know how the medicine affects you. Inform your employer if your work involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 5 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver and kidney damage. Chlorpheniramine may cause tolerance and dependence. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps clear nasal passages and reduce congestion without medication.
Evidence: Well-establishedCan temporarily relieve nasal congestion.
Evidence: LimitedAlternative for allergic rhinitis with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after oral administration.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for coldova-ds syrup
View AllAlternative brands with exact same active ingredient:
-
dencold oral suspensionBMW Pharmaco India Pvt. Ltd. ₹25.31 15.6% CHEAPER
-
ezinoz oral suspensionDR Best pharmaceuticals Pvt Ltd ₹26.25 12.5% CHEAPER
-
exhale p suspensionIndian Pharmaceuticals ₹30.84 2.8% COSTLIER
-
vista cold suspensionInnova Formulations Pvt Ltd ₹35.00 16.7% COSTLIER
-
nonucold syrupAmbience Pharma ₹37.50 25% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage from paracetamol. - Myth: This medicine is safe for everyone.
Fact: It is not safe for newborns, people with certain medical conditions, or those taking MAO inhibitors.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Paracetamol syrup (generic)
Brand Alternatives
- Anicold Syrup