kunim cold syrup - Chlorpheniramine Maleate (0.5mg) + Paracetamol (125mg) medicine

Alcicold Oral Suspension: Complete Medicine Guide

No reviews yet
🏭 Stenkem Molecules Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain or yellowing of eyes or skin
  • Blood in vomit or stool
  • Irregular heartbeat or chest pain
  • Confusion or severe dizziness
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is kunim cold syrup used for?

This medicine is a combination of chlorpheniramine maleate (an antihistamine) and paracetamol (a pain reliever and fever reducer) used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever.

  • Generic Name: Chlorpheniramine Maleate (0.5mg) + Paracetamol (125mg)
  • Manufacturer: Stenkem Molecules Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 kunim cold syrup के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में पानी आना और हल्के बुखार में राहत देने के लिए इस्तेमाल की जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना और पेट खराब होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई या लीवर की समस्या हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के अनुसार ही लें। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 kunim cold syrup Uses & Benefits

[{"condition":"Common cold","description":"Relieves symptoms such as runny nose, sneezing, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Helps reduce sneezing, runny nose, and itchy, watery eyes caused by allergies.","evidence":"Well-established"},{"condition":"Upper respiratory tract allergies","description":"Provides symptomatic relief from allergic reactions affecting the nose and throat.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic rhinitis

Also treats: Upper respiratory tract allergies, Sneezing, Runny nose

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (0.5mg) + Paracetamol (125mg)
Brand Namekunim cold syrup
ManufacturerStenkem Molecules Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Shake the bottle well before each use to ensure uniform mixing of the suspension.
2
Use a proper measuring device to avoid under- or over-dosing.
3
Avoid giving this medicine to children under 2 years without doctor's advice.
4
Do not use this medicine for more than 5 days without consulting a doctor.
5
Be cautious when driving or operating machinery due to drowsiness.
6
Inform your doctor if you have liver or kidney problems before taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly used for this symptom.
Likely Use
✅
Sneezing
This medicine helps relieve sneezing.
Likely Use
✅
Mild fever
Paracetamol in this medicine reduces fever.
Likely Use
❌
Severe headache
This medicine is not a primary treatment for severe headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly and almost completely absorbed from the gastrointestinal tract. The suspension formulation may provide faster absorption compared to solid dosage forms.
DistributionChlorpheniramine maleate is widely distributed throughout the body, including the central nervous system. Paracetamol distributes rapidly into most body tissues, with high concentrations in the liver, kidney, and cerebrospinal fluid.
Protein BindingChlorpheniramine maleate is approximately 70% bound to plasma proteins. Paracetamol is only minimally bound to plasma proteins (about 10-25%).
MetabolismChlorpheniramine maleate is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6 and CYP3A4. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), which is normally detoxified by glutathione.
Half-LifeThe elimination half-life of chlorpheniramine maleate is approximately 12-15 hours in adults. The elimination half-life of paracetamol is about 2-3 hours in adults with normal liver function.
ExcretionChlorpheniramine maleate and its metabolites are excreted primarily in the urine. Paracetamol metabolites are excreted mainly in the urine, with about 90% of the dose excreted within 24 hours.
BioavailabilityThe oral bioavailability of chlorpheniramine maleate is approximately 25-50% due to first-pass metabolism. Paracetamol has a high oral bioavailability of about 80-100%.
Onset of ActionThe onset of action for chlorpheniramine is about 30-60 minutes after oral administration. Paracetamol begins to reduce fever and pain within 30-60 minutes.
Peak Plasma TimePeak plasma concentrations of chlorpheniramine are reached in about 2-6 hours. Paracetamol reaches peak plasma levels in about 30-60 minutes.
Duration of ActionThe effects of chlorpheniramine last about 4-6 hours, while paracetamol provides relief for about 4-6 hours.

How It Works

This medicine combines an antihistamine and an analgesic-antipyretic. Chlorpheniramine maleate works by competitively blocking histamine H1 receptors, thereby reducing allergic symptoms such as sneezing, runny nose, and watery eyes. Paracetamol acts centrally to relieve pain and reduce fever, though its exact mechanism is not fully understood; it is believed to inhibit prostaglandin synthesis in the central nervous system.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine maleate binds to H1 receptors on effector cells, preventing histamine from triggering allergic responses such as sneezing, itching, and vasodilation.
2
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and blocks central H1 receptors, leading to sedation and reduced alertness.
3
Prostaglandin synthesis inhibition: Paracetamol inhibits prostaglandin synthesis in the central nervous system, which helps lower fever and alleviate pain.
4
Antipyretic effect: Paracetamol acts on the hypothalamic heat-regulating center to produce sweating and vasodilation, thereby reducing body temperature.

💡 How to Take kunim cold syrup

Strength: Each 5 mL of suspension contains Chlorpheniramine Maleate 0.5 mg and Paracetamol 125 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the correct dose.
3Take orally, with or without food.
4Follow the dosage instructions provided by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 mL (2 teaspoons) every 4 to 6 hours as needed, not to exceed 4 doses in 24 hours. However, dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects, especially drowsiness and anticholinergic effects. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseFor adults: Maximum 8 tablets or 40 mL of suspension in 24 hours. Do not exceed recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of kunim cold syrup

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. Usually resolves with continued use.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Liver damage (Rare (<0.1%))
Seek medical help if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Blood disorders (Very rare (<0.01%))
Report unusual bleeding, bruising, or fatigue to your doctor immediately.

⚠️ Rare Side Effects

Photosensitivity
Use sunscreen and protective clothing when outdoors.
Urinary retention
Consult doctor if you have difficulty urinating.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Major
Warfarin Moderate
CNS depressants Moderate
Anticholinergics Moderate
Cholestyramine Moderate
Antacids Minor
Caffeine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol
  • Warfarin

⚡ Moderate Interactions

  • CNS depressants (e.g., benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Cholestyramine

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness and the risk of liver damage, especially due to the paracetamol component.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, paracetamol, or any component","Severe liver disease","Narrow-angle glaucoma","Urinary retention","MAOI therapy within 14 days"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol.","Do not exceed recommended dose.","Use with caution in patients with liver or kidney disease.","Consult doctor before use in pregnancy or breastfeeding.","Do not use for longer than directed without medical advice."]

🤱 Lactation Safety

Chlorpheniramine and paracetamol are excreted in breast milk in small amounts. Caution is advised; consult your doctor before use.

💊 Overdose Management

Overdose can cause severe liver damage due to paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal and acetylcysteine.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Do not consume alcohol while taking this medicine, as it can increase drowsiness and the risk of liver damage. Inform your doctor if you have liver or kidney disease, glaucoma, difficulty urinating, or any chronic illness. Do not use this medicine for longer than directed without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Do not take other medicines containing paracetamol while on this medicine to avoid overdose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as drowsiness, confusion, and anticholinergic effects. Use with caution and consult a doctor for dose adjustment.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy or are pregnant. The safety of this combination in pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Avoid exposure to allergens if you have allergies.
💧
Use a humidifier to ease nasal congestion.
🧘
Wash your hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel drowsy or dizzy from this medicine. Light activities are fine if you feel well.

🥗 Diet Recommendations

Include warm soups and broths.
Avoid cold beverages if you have a sore throat.
Eat light, easily digestible meals.
Stay hydrated with water and herbal teas.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is best to avoid these activities until you know how the medicine affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 5 days, if they worsen, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol may increase the risk of liver damage, especially with high doses or alcohol consumption. Chlorpheniramine may cause tolerance to its sedative effects. Regular monitoring of liver function may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal rinse

Helps relieve nasal congestion without medication.

Evidence: Well-established
Steam inhalation

Can help ease breathing and loosen mucus.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule accordingly, but do not exceed the maximum daily dose. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergies
She experienced sneezing, runny nose, and itchy eyes every spring. Her doctor prescribed this medicine. She took it as directed and found significant relief within 30 minutes. She noted drowsiness, so she took it at bedtime.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while providing relief from allergy symptoms.
👤 A 5-year-old child with common cold
The child had a runny nose, mild fever, and sneezing. The pediatrician recommended this medicine in a weight-based dose. The parents measured the dose carefully and gave it with food. The child's symptoms improved within a day.
💡 Lesson: Always follow pediatric dosing instructions and use a proper measuring device for liquid medicines.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral administration.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: Is it safe for children?

A: It may be used in children above 2 years under medical supervision. Consult a pediatrician for appropriate dosing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for kunim cold syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: It only relieves symptoms; it does not cure the viral infection.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases drowsiness and risk of liver damage.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine + Paracetamol suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Chlorpheniramine + Paracetamol","uses":"Cold and allergy symptoms","sedation":"Moderate"},{"medicine":"Cetirizine + Paracetamol","active_ingredients":"Cetirizine + Paracetamol","uses":"Cold and allergy symptoms","sedation":"Low"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory