Dmr-cc Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, tongue, or throat
- Severe rash or hives
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Blood in sputum or vomit
- Yellowing of skin or eyes (jaundice)
If experiencing severe symptoms, call emergency services immediately.
What is koxma-cc tablet used for?
This medicine is a combination syrup of Ambroxol (30 mg) and Cetirizine (5 mg) per 5 mL. It is used to treat productive cough with thick mucus and allergic symptoms like runny nose and sneezing. It works by thinning mucus and blocking histamine. It is not for dry cough and should not be used in children under 2 years.
- Generic Name: Ambroxol (30mg) + Cetirizine (5mg)
- Manufacturer: West-Coast Pharmaceutical Works Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 koxma-cc tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एम्ब्रोक्सोल और सेटीरिज़ीन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना और आंखों में पानी आना के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और एलर्जी को कम करती है। यह सूखी खांसी के लिए नहीं है और 2 साल से छोटे बच्चों को नहीं दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, चक्कर आना और पेट में असहजता शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई या दिल की धड़कन अनियमित लगे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। यदि आपको नींद आती है तो वाहन चलाने या मशीन चलाने से बचें। इस दवा के साथ शराब न लें। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। सूखी खांसी के लिए इसका उपयोग न करें। 7 दिनों से अधिक उपयोग करने से पहले डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 koxma-cc tablet Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin mucus, making it easier to expel, thereby relieving chest congestion.","evidence":"Well-established"},{"condition":"Allergic bronchitis","description":"Reduces allergic symptoms such as sneezing, runny nose, and watery eyes while also clearing mucus.","evidence":"Well-established"},{"condition":"Upper respiratory tract infections with allergic component","description":"Provides symptomatic relief from cough and allergic rhinitis symptoms associated with common cold.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chronic sinusitis with post-nasal drip","description":"Sometimes prescribed to reduce mucus viscosity and allergic symptoms, but not a standard approved use.","evidence":"Limited"}]
Primary treatment for: Productive cough with allergic symptoms
Also treats: Allergic bronchitis, Common cold with cough, Upper respiratory tract infections
📋 Drug Information
| Generic Name(s) | Ambroxol (30mg) + Cetirizine (5mg) |
| Brand Name | koxma-cc tablet |
| Manufacturer | West-Coast Pharmaceutical Works Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and promotes ciliary clearance, making cough more productive. Cetirizine is a selective peripheral H1-receptor antagonist that inhibits histamine-mediated allergic responses, reducing sneezing, rhinorrhea, and lacrimation. Together, they address both mucus congestion and allergic symptoms.
Mechanism Steps
💡 How to Take koxma-cc tablet
Strength: Each 5 mL of syrup contains Ambroxol 30 mg and Cetirizine 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 mL (1-2 teaspoons) taken orally two to three times a day, depending on the severity of symptoms and the doctor's prescription. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Shake the bottle well before use. Use a measuring cup or spoon for accurate dosing. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 2 years of age. For children above 2 years, the dose is typically based on age and weight, and must be determined by a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative effects of cetirizine. Dose adjustment may be necessary based on renal function. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with renal impairment, dose reduction of cetirizine is recommended. For creatinine clearance 30-49 mL/min, the dose should be reduced; for creatinine clearance <30 mL/min, further reduction or alternative therapy may be needed. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with severe hepatic impairment, dose adjustment may be required. Use with caution and under medical supervision. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 30 mL (providing 180 mg Ambroxol and 30 mg Cetirizine) per day, but this should not be exceeded. Individual dosing must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of koxma-cc tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Moderate | |
| Theophylline | Moderate | |
| Ritonavir | Minor | |
| Sedative hypnotics | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- Theophylline
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of cetirizine, leading to increased drowsiness, dizziness, and impaired coordination. This can affect your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ambroxol, Cetirizine, or any component of the formulation","Children under 2 years of age","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with renal or hepatic impairment.","Not recommended for children under 2 years.","Do not use for dry cough or for more than 7 days without medical advice.","Consult doctor if you have a history of seizures, urinary retention, or glaucoma.","Pregnant and breastfeeding women should consult a doctor before use."]
🤱 Lactation Safety
Cetirizine is excreted in breast milk in small amounts and may cause drowsiness in the infant. Ambroxol's safety during breastfeeding is not well established. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, nausea, vomiting, and in children, paradoxical excitation. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery if you feel drowsy. Do not consume alcohol while taking this medicine as it can increase drowsiness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for a dry cough or for more than 7 days without consulting a doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the sedative and anticholinergic effects of cetirizine. Dose adjustment may be needed based on renal function. Monitor for dizziness, confusion, and urinary retention.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, consult your doctor before using this medicine, as it may interact with anesthetics or other medications. It may also affect your ability to recover if drowsiness is a concern.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues. Also, if you are scheduled for surgery, discuss with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience drowsiness or dizziness, avoid strenuous exercise or activities requiring alertness. Light exercise like walking may be fine if you feel well. Consult your doctor before starting any exercise routine while on this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid such activities until you know how it affects you. It may also cause dry mouth, so keep water handy. Otherwise, it should not significantly impact your daily work life.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine without medical supervision is not recommended. Prolonged use of cetirizine may lead to tolerance or increased side effects. Ambroxol is generally well-tolerated. Regular monitoring of renal and hepatic function may be needed if used for extended periods. Consult your doctor for periodic review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal passages and reduce allergic symptoms.
Evidence: ModerateIf mucus is not a major issue, a plain antihistamine may suffice.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines. Do not leave it in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ambroxol starts working within 30-60 minutes, while Cetirizine's effect begins within 1 hour. You may notice improvement in cough and allergic symptoms within a few hours.
A: Yes, it can be taken with antibiotics if prescribed, but always consult your doctor to ensure no interactions.
A: It is not recommended for children under 2 years. For older children, consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🔄 Substitutes for koxma-cc tablet
View AllAlternative brands with exact same active ingredient:
-
trussex dmr tabletHamax Pharmaceuticals ₹32.81 30% CHEAPER
-
ambrocet syrupSimcare Pharma ₹44.56 4.9% CHEAPER
-
zine ax 5mg/30mg tabletNebulae Pharma ₹45.00 4% CHEAPER
-
Tbrox-CT SyrupTechnica Lab Pvt Ltd ₹45.00 4% CHEAPER
-
coldiva-dmr tabletMediva Lifecare ₹46.88 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for productive cough with mucus and allergic symptoms. It is not effective for dry cough. - Myth: It is safe to take this medicine for a long time without doctor's advice.
Fact: Prolonged use without medical supervision can lead to side effects and may mask underlying conditions. - Myth: This medicine can be given to infants for cough.
Fact: This medicine is not recommended for children under 2 years due to safety concerns.
🔄 Alternative Options
Generic Alternatives
- Ambroxol + Cetirizine syrup (various manufacturers)
Brand Alternatives
- Dmr-cc syrup