acnegel-b gel - Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w) medicine

Aclind BP 5% Gel: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 West-Coast Pharmaceutical Works Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for acne vulgaris.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
  • Severe diarrhea, abdominal cramps, or blood in stool.
  • Extreme skin redness, blistering, or peeling.
  • Signs of infection: pus, increased pain, warmth.
  • No improvement after 8-12 weeks of consistent use.
  • New or worsening symptoms.

If experiencing severe symptoms, call emergency services immediately.

What is acnegel-b gel used for?

This medicine is a topical gel containing benzoyl peroxide 5% and clindamycin 1%, used to treat moderate to severe acne by killing bacteria and reducing inflammation. Apply a thin layer to affected areas once or twice daily as directed by your doctor.

  • Generic Name: Benzoyl Peroxide + Clindamycin
  • Manufacturer: West-Coast Pharmaceutical Works Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acnegel-b gel के बारे में (Hindi Summary)

उपयोग: यह दवा मुँहासे (एक्ने) के इलाज के लिए इस्तेमाल की जाने वाली टॉपिकल जेल है। इसमें बेंज़ॉयल पेरोक्साइड 5% और क्लिंडामाइसिन 1% होता है। यह मुँहासे पैदा करने वाले बैक्टीरिया को मारती है और सूजन को कम करती है। यह मध्यम से गंभीर मुँहासे के लिए प्रभावी है। इसे चिकित्सक के निर्देशानुसार प्रभावित त्वचा पर पतली परत में लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा का सूखना, छीलना, लालिमा, जलन और खुजली शामिल हैं। ये आमतौर पर हल्के होते हैं और उपयोग जारी रखने पर कम हो जाते हैं। दुर्लभ मामलों में गंभीर एलर्जी, गंभीर दस्त या आंतों की सूजन हो सकती है। यदि आपको लगातार दस्त, पेट में ऐंठन या मल में खून दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। आँखों, होंठों और म्यूकस झिल्ली से बचाएं। उपयोग से पहले चेहरे को सौम्य क्लेंज़र से धोएं और सुखाएं। धूप से बचाव के लिए सनस्क्रीन लगाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 acnegel-b gel Uses & Benefits

[{"condition":"Acne vulgaris (moderate to severe)","description":"Reduces inflammatory and non-inflammatory acne lesions by killing Cutibacterium acnes and decreasing inflammation.","evidence":"Well-established"},{"condition":"Inflammatory acne","description":"Targets papules and pustules through combined antibacterial and anti-inflammatory actions.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Rosacea","description":"Sometimes used off-label for rosacea with inflammatory papules, but evidence is limited.","evidence":"Limited"},{"condition":"Hidradenitis suppurativa","description":"May be used as adjunctive therapy in mild cases, but not standard.","evidence":"Limited"}]

Primary treatment for: Acne vulgaris

Also treats: Inflammatory acne, Comedonal acne

📋 Drug Information

Generic Name(s)Benzoyl Peroxide + Clindamycin
Brand NameAclind BP 2.5% Gel
ManufacturerWest-Coast Pharmaceutical Works Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassTopical Antibiotic + Keratolytic
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer to the entire affected area, not just individual pimples.
2
Start with once-daily application to assess tolerance, then increase if advised.
3
Use a non-comedogenic moisturizer to manage dryness.
4
Avoid using abrasive scrubs or other irritating products concurrently.
5
Be patient; visible improvement may take 4-8 weeks.
6
Always use sunscreen, as benzoyl peroxide increases sun sensitivity.
7
Do not use on broken or inflamed skin without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Inflammatory acne (papules, pustules)
This medicine is commonly prescribed for this.
Likely Use
Comedonal acne (blackheads, whiteheads)
This medicine can help unclog pores.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information. Systemic absorption of clindamycin after topical application is minimal but can occur, especially if applied to large areas or broken skin.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismClindamycin is metabolized in the liver, primarily by CYP3A4. Benzoyl peroxide is converted to benzoic acid in the skin.
Half-LifeNot established from the available information.
ExcretionClindamycin and its metabolites are excreted in urine and bile. Benzoyl peroxide metabolites are excreted renally.
BioavailabilityNot established from the available information.
Onset of ActionImprovement in acne lesions may be seen within 2-4 weeks, but full effect may take 8-12 weeks.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two agents with complementary mechanisms. Benzoyl peroxide is a powerful oxidizing agent that releases free radicals, which disrupt bacterial cell membranes and proteins, leading to the death of Cutibacterium acnes. It also has mild comedolytic and anti-inflammatory properties. Clindamycin is a lincosamide antibiotic that binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Together, they reduce bacterial load, inflammation, and comedone formation.

Mechanism Steps

1
Benzoyl peroxide releases oxygen: Benzoyl peroxide decomposes in the skin to release oxygen, creating an environment hostile to anaerobic bacteria like Cutibacterium acnes.
2
Clindamycin inhibits protein synthesis: Clindamycin binds to the bacterial 50S ribosomal subunit, blocking peptide bond formation and preventing bacterial protein synthesis.
3
Reduction of inflammation: Both agents reduce the release of inflammatory mediators, leading to decreased redness and swelling of acne lesions.
4
Comedolysis: Benzoyl peroxide helps to unclog pores by reducing keratin plugging, allowing better penetration of clindamycin.

💡 How to Take acnegel-b gel

Strength: Gel containing Benzoyl Peroxide 5% w/w and Clindamycin 1% w/w.

1Wash your hands and the affected area with a mild cleanser.
2Pat the skin dry gently.
3Apply a thin layer of the gel to the affected areas.
4Avoid contact with eyes, lips, and mucous membranes.
5Wash your hands after application.
6Use sunscreen during the day.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected areas once or twice daily, or as directed by your doctor. Wash the area gently with a mild cleanser and pat dry before application. The dose and frequency must be individualized by a qualified clinician based on the severity of acne, skin sensitivity, and response to treatment. Do not apply more than prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. Use with caution and monitor for skin irritation.
Renal ImpairmentNo dosage adjustment is required for renal impairment when used topically, as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required for hepatic impairment when used topically, as systemic absorption is minimal.
Maximum Daily DoseNot established from the available information. Use as directed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
Not applicable
This medicine is applied topically and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of acnegel-b gel

✅ Common Side Effects

Dry skin (Common (10-30%))
Apply a moisturizer and reduce frequency if severe.
Peeling (Common (10-30%))
Use gentle cleansers and moisturizers; avoid scrubbing.
Redness (Common (10-30%))
Usually subsides; if persistent, consult doctor.
Burning or stinging (Common (5-15%))
Apply less frequently or use a lower strength if advised.
Itching (Common (5-15%))
Avoid scratching; consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Pseudomembranous colitis (Rare (<0.1%))
Stop use and seek medical help if you develop severe or persistent diarrhea, abdominal cramps, or blood in stool.
Severe skin irritation or blistering (Rare (<0.1%))
Discontinue use and consult a doctor.

⚠️ Rare Side Effects

Contact dermatitis
Stop use and consult a dermatologist.
Fungal skin infections
Consult doctor for appropriate antifungal treatment.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tretinoin Major
Salicylic acid Major
Erythromycin Moderate
Neuromuscular blockers Major
PABA sunscreens Minor

🚨 Major Interactions

  • Other topical acne products (e.g., tretinoin, salicylic acid)
  • Neuromuscular blocking agents

⚡ Moderate Interactions

  • Erythromycin
  • Kaolin-pectin antidiarrheals

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol consumption may worsen acne and should be limited.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to benzoyl peroxide, clindamycin, or any component","History of regional enteritis or ulcerative colitis","History of antibiotic-associated colitis","Use on broken or eczematous skin"]

⚠️ Warnings & Precautions

["For external use only.","Avoid contact with eyes, lips, and mucous membranes.","May cause skin irritation; if severe, discontinue use.","Clindamycin can cause severe colitis; monitor for diarrhea.","Benzoyl peroxide can bleach hair and colored fabrics.","Use sunscreen and protective clothing during treatment.","Do not use on large areas of skin without medical advice.","Keep away from children."]

🤱 Lactation Safety

It is not known whether topical clindamycin or benzoyl peroxide is excreted in breast milk. Consult your doctor before use. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Overdose with topical application is unlikely. If excessive amounts are applied, wash the area thoroughly with water. If ingested, seek medical attention immediately. Symptoms of oral overdose may include nausea, vomiting, and diarrhea.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Apply a thin layer to affected areas after washing with a mild cleanser and patting dry. Avoid contact with eyes, lips, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken, sunburned, or irritated skin. Use sunscreen daily and avoid excessive sun exposure, as benzoyl peroxide can increase sun sensitivity. Do not use other topical acne products unless advised by your doctor, as this may cause irritation. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep out of reach of children. Do not share this medicine with others. If no improvement is seen after 6-8 weeks, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have thinner, more sensitive skin. Use with caution and monitor for irritation. No dosage adjustment is typically needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of topical clindamycin and benzoyl peroxide during pregnancy is not fully established, and your doctor may recommend alternative treatments.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine on or near the surgical site to avoid irritation or infection.

🦷 Dental Procedures

No specific precautions for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Cleanse your face gently twice daily with a mild cleanser.
🥗
Avoid picking or squeezing pimples to prevent scarring.
😴
Use non-comedogenic moisturizers and sunscreens.
💧
Maintain a balanced diet and stay hydrated.
🧘
Manage stress through relaxation techniques, as stress can worsen acne.
🌞
Get adequate sleep to support skin health.

🏋️ Exercise Considerations

Exercise is generally safe while using this medicine. However, sweat may irritate the skin, so wash your face gently after workouts. Avoid sharing towels or equipment that may spread bacteria.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Reduce intake of high-glycemic foods that may trigger acne.
Stay well hydrated by drinking adequate water.
Limit dairy and sugary beverages if they seem to worsen your acne.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience skin irritation or allergic reaction, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor, especially if you are seeing improvement. Stopping too early may cause acne to return. If you experience severe side effects, stop use and seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe for acne management. However, prolonged use of topical antibiotics like clindamycin can lead to bacterial resistance. It is important to use it as prescribed and not for extended periods without medical supervision. Regular follow-up with your doctor is recommended to assess continued need and to monitor for any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Salicylic acid cleansers

Can help unclog pores and reduce mild acne.

Evidence: Well-established
Oral antibiotics

For moderate to severe acne, oral antibiotics like doxycycline may be prescribed.

Evidence: Well-established
Hormonal therapy

For women with hormonal acne, oral contraceptives or spironolactone may be options.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. When flying, keep it in your carry-on luggage. If traveling across time zones, continue your regular application schedule as close as possible. Customs may require documentation for prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 22-year-old college student with moderate acne
Started using this medicine once daily as prescribed. Initially experienced mild dryness and peeling, which subsided after two weeks with moisturizer use. After 8 weeks, inflammatory lesions reduced significantly. Emphasized not to skip applications.
💡 Lesson: Consistent use and proper skin care can lead to good results despite initial irritation.
👤 A 30-year-old woman with hormonal acne
Used this medicine twice daily for 12 weeks. Noticed improvement in pustules but developed dry patches. Reduced frequency to once daily and added a gentle moisturizer, which helped. Acne remained controlled.
💡 Lesson: Adjusting frequency and using adjunctive skin care can improve tolerability without losing efficacy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement in 2-4 weeks, but full effects may take 8-12 weeks of consistent use.

Q: Can I use this medicine with other acne products?

A: Consult your doctor before combining with other topical acne treatments, as it may increase irritation.

Q: Is this medicine safe during pregnancy?

A: Consult your doctor. The safety of topical clindamycin and benzoyl peroxide during pregnancy is not fully established.

Q: What should I do if I get severe irritation?

A: Stop using the medicine and consult your doctor. They may adjust the frequency or recommend a different treatment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it bleach my clothes?
  • Can I wear makeup while using this medicine?
  • Does it interact with my other acne treatments?
  • What if I miss a dose?
  • Can I use it on my back and chest?

🔄 Substitutes for acnegel-b gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine works overnight.
    Fact: It may take several weeks to see noticeable improvement.
  • Myth: More application means faster results.
    Fact: Applying more than directed can cause severe irritation without speeding up results.
  • Myth: You can stop using it once acne clears.
    Fact: Stopping too soon may lead to recurrence; follow your doctor's advice.

🔄 Alternative Options

Generic Alternatives

  • Benzoyl peroxide 5% + clindamycin 1% gel (generic)

Brand Alternatives

  • Acnelak-CL
  • Clindac A
  • Deriva-CL
  • Eclind
  • Peroclin

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Benzoyl peroxide 5% + clindamycin 1%","form":"Gel","frequency":"Once or twice daily"},{"medicine":"Adapalene + clindamycin","composition":"Adapalene 0.1% + clindamycin 1%","form":"Gel","frequency":"Once daily"},{"medicine":"Tretinoin + clindamycin","composition":"Tretinoin 0.025% + clindamycin 1%","form":"Gel","frequency":"Once daily"}]

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