korisuma tablet - Carisoprodol (350mg) medicine

Carisoprodol 350mg Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Holy Evolution Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term use in acute musculoskeletal conditions.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe drowsiness or difficulty staying awake
  • Slow or shallow breathing
  • Confusion or hallucinations
  • Seizures or unusual movements
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Signs of liver problems (yellowing of eyes or skin, dark urine, severe abdominal pain)
  • Withdrawal symptoms (anxiety, tremors, insomnia) after stopping the medicine

If experiencing severe symptoms, call emergency services immediately.

What is korisuma tablet used for?

This medicine is a muscle relaxant used for short-term relief of muscle spasms and pain. It works by blocking pain signals in the brain and spinal cord. It is usually taken three times a day and at bedtime, but only for up to 2-3 weeks because it can be habit-forming.

  • Generic Name: Carisoprodol (350mg)
  • Manufacturer: Holy Evolution Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 korisuma tablet के बारे में (Hindi Summary)

उपयोग: यह दवा कैरिसोप्रोडोल 350 मिलीग्राम युक्त एक मसल रिलैक्सेंट है। इसका उपयोग मांसपेशियों में ऐंठन, खिंचाव और दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह दवा मस्तिष्क और रीढ़ की हड्डी में दर्द के संकेतों को रोककर मांसपेशियों को आराम देती है। यह आमतौर पर 2 से 3 सप्ताह से अधिक समय तक नहीं ली जानी चाहिए क्योंकि इसकी लत लग सकती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द और जी मिचलाना शामिल हैं। कुछ लोगों को धुंधली दृष्टि, मुँह सूखना या पेट खराब हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, दौरे या त्वचा पर गंभीर प्रतिक्रिया हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न बढ़ाएं और न ही लंबे समय तक लें। शराब और नींद लाने वाली अन्य दवाओं से बचें। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, तब तक वाहन न चलाएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। दवा को बच्चों से दूर रखें और कमरे के तापमान पर स्टोर करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 korisuma tablet Uses & Benefits

[{"condition":"Muscle spasms","description":"This medicine helps relieve acute, painful muscle spasms associated with musculoskeletal conditions.","evidence":"Well-established for short-term use"},{"condition":"Musculoskeletal pain","description":"It is used for short-term relief of pain and stiffness from strains, sprains, and other muscle injuries.","evidence":"Well-established for short-term use"},{"condition":"Low back pain","description":"Sometimes prescribed for short-term relief of acute low back pain with muscle spasm.","evidence":"Limited, short-term use only"}]

Off-label uses: [{"condition":"Tension headache","description":"Rarely used off-label for tension-type headaches associated with muscle tightness.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"Not recommended for routine use in fibromyalgia due to lack of evidence and risk of dependence.","evidence":"Insufficient"}]

Primary treatment for: Muscle spasms

Also treats: Musculoskeletal pain, Acute low back pain

📋 Drug Information

Generic Name(s)Carisoprodol (350mg)
Brand Namekorisuma tablet
ManufacturerHoly Evolution Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassSkeletal muscle relaxant- Centrally acting
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep in the original container, tightly closed.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed, usually three times a day and at bedtime.
2
Take it with food or milk if it upsets your stomach.
3
Avoid alcohol and other sedating medicines while taking this medicine.
4
Do not drive or operate heavy machinery until you know how this medicine affects you.
5
Do not take this medicine for more than 2-3 weeks without your doctor's advice.
6
If you have been taking it for a long time, do not stop suddenly; talk to your doctor about tapering.
7
Report any signs of dependence, such as craving or needing more medicine, to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Muscle spasms
This medicine is commonly prescribed for this.
Likely Use
✅
Acute back pain with muscle tightness
This medicine may be used short-term for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Chronic pain without muscle spasm
This medicine is not recommended for long-term chronic pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. It is rapidly absorbed, but exact bioavailability data are not established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismThis medicine is metabolized in the liver, primarily by the CYP2C19 enzyme, to its active metabolite meprobamate. Meprobamate is then further metabolized and eliminated.
Half-LifeThe elimination half-life of this medicine is approximately 2 hours, while its active metabolite meprobamate has a half-life of about 10 hours.
ExcretionThis medicine and its metabolites are excreted mainly in the urine, primarily as meprobamate and its glucuronide conjugate.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action is typically within 30 minutes to 1 hour after taking a dose.
Peak Plasma TimePeak plasma levels are usually reached within 1 to 2 hours after oral administration.
Duration of ActionThe muscle relaxant effect usually lasts about 4 to 6 hours, but sedation may last longer.

How It Works

This medicine works in the central nervous system to produce muscle relaxation and pain relief. It is metabolized in the liver to meprobamate, which is believed to be responsible for much of its sedative and muscle-relaxant effects. It blocks pain signals between the nerves and the brain, helping to reduce muscle spasm and associated pain. It does not act directly on the muscles themselves.

Mechanism Steps

1
Absorption and metabolism: After you take this medicine by mouth, it is absorbed and then broken down in the liver into meprobamate, its active metabolite.
2
Central nervous system action: Meprobamate acts on the brain and spinal cord to reduce the transmission of pain signals and to relax muscles.
3
Muscle relaxation: By reducing nerve signals that cause muscle tightness, this medicine helps relieve muscle spasms and the pain they cause.
4
Sedation: The same action also produces drowsiness, which can help you rest but may affect your ability to drive or operate machinery.

💡 How to Take korisuma tablet

Strength: Carisoprodol 350 mg immediate-release tablet

1Take this medicine by mouth with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole. Do not crush, chew, or break it unless your doctor tells you to.
4Take it at the same times each day to maintain a consistent level in your body.
5Do not take more than the prescribed dose or for longer than recommended.
6If you miss a dose, follow the missed dose instructions.
7Do not stop taking this medicine suddenly without talking to your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 350 mg taken by mouth three times a day and at bedtime. However, the dose and duration must be individualized by a qualified clinician based on your condition, age, liver and kidney function, and other medicines you are taking. Do not take more than the prescribed dose. This medicine is usually prescribed for short-term use only, up to 2 to 3 weeks.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are more sensitive to the sedative effects of this medicine. The dose may need to be reduced, and it should be used with caution. Consult your doctor for individualized dosing.
Renal ImpairmentIn patients with kidney disease, this medicine may accumulate and cause increased side effects. Dose adjustment may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with liver disease, this medicine should be used with caution. Dose reduction may be needed. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 1400 mg (four 350 mg tablets) per day. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels and side effects.
Alcohol
Avoid
Increases sedation and risk of respiratory depression.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of korisuma tablet

✅ Common Side Effects

Drowsiness (Common (more than 10%))
Avoid driving or operating machinery. If drowsiness is severe or persistent, contact your doctor.
Dizziness (Common (5-10%))
Get up slowly from sitting or lying down. If dizziness continues, talk to your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or does not go away, consult your doctor.
Nausea (Common (5-10%))
Take this medicine with food or milk to reduce stomach upset. If nausea persists, tell your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (less than 0.1%))
Seek emergency medical help immediately if you have rash, itching, swelling of the face, lips, or throat, or difficulty breathing.
Drug dependence and withdrawal (Uncommon (0.1-1%) with long-term use)
Do not stop suddenly. Talk to your doctor about tapering. Seek help if you feel you cannot control your use.
Seizures (Rare (less than 0.1%))
Call emergency services if you have a seizure. Do not drive or operate machinery.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (less than 0.01%))
Stop this medicine and seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Low blood pressure
Seek medical attention if you feel faint or have a sudden drop in blood pressure.
Blood disorders (e.g., aplastic anemia)
Report unusual tiredness, bruising, or bleeding to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Opioids Major
Benzodiazepines Major
MAO inhibitors Major
Antihistamines Moderate
Tricyclic antidepressants Moderate
CYP2C19 inhibitors Moderate
Antacids Minor

🚨 Major Interactions

  • Alcohol
  • Opioid painkillers (e.g., codeine, morphine)
  • Benzodiazepines (e.g., diazepam, lorazepam)
  • MAO inhibitors (e.g., phenelzine, tranylcypromine)

⚡ Moderate Interactions

  • Antihistamines (e.g., diphenhydramine)
  • Tricyclic antidepressants (e.g., amitriptyline)
  • CYP2C19 inhibitors (e.g., omeprazole, fluoxetine)

🍷 Alcohol Interaction

Do not drink alcohol while taking this medicine. Alcohol increases the sedative effects of this medicine and can cause severe drowsiness, dizziness, and difficulty breathing. It also increases the risk of dependence and liver problems.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Carisoprodol, meprobamate, or any ingredient in this medicine","Porphyria (a rare blood disorder)","History of drug dependence or substance abuse","Severe liver or kidney disease","Children under 12 years of age"]

⚠️ Warnings & Precautions

["This medicine can cause drowsiness and dizziness. Do not drive or operate machinery until you know how it affects you.","Avoid alcohol and other central nervous system depressants while taking this medicine.","Do not take this medicine for longer than 2 to 3 weeks unless directed by your doctor, as it can be habit-forming.","Do not stop taking this medicine suddenly after long-term use; withdrawal symptoms may occur.","Use with caution in the elderly, as they are more sensitive to the sedative effects.","Tell your doctor if you have liver or kidney disease, as dose adjustment may be needed.","This medicine may cause seizures in some people. Report any unusual movements or seizures to your doctor.","Keep this medicine out of reach of children and store it safely to prevent accidental ingestion."]

🤱 Lactation Safety

This medicine passes into breast milk and may cause drowsiness in a nursing infant. It is not recommended while breastfeeding. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose of this medicine can cause severe drowsiness, confusion, coma, shock, and respiratory depression. If you suspect an overdose, seek emergency medical help immediately. Treatment is supportive and may include stomach emptying, activated charcoal, and monitoring of vital signs. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it for longer than recommended, as this can lead to dependence. Avoid alcohol and other medicines that make you sleepy, such as opioid painkillers, benzodiazepines, and antihistamines, because they can increase drowsiness and breathing problems. Do not drive or use machines until you know how this medicine affects you. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. If you have liver or kidney disease, your doctor may need to adjust your dose or monitor you more closely. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat. Do not stop taking this medicine suddenly without talking to your doctor, especially if you have been taking it for more than a few weeks.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and dizzying effects of this medicine. They are at higher risk of falls and confusion. The dose may need to be reduced, and it should be used with caution. Regular monitoring for side effects is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, talk to your doctor before taking this medicine. It should be used during pregnancy only if clearly needed, as it may harm the unborn baby. Discuss alternative treatments for muscle spasms that are safer during pregnancy.

🏥 Post-Surgery Considerations

This medicine may be used after surgery for short-term relief of muscle spasms, but it can increase sedation when combined with other postoperative pain medicines. Your doctor will decide if it is appropriate for you and will monitor you closely.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It can increase drowsiness when combined with sedatives or anesthetics used in dentistry. Your dentist may adjust your treatment plan accordingly.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your muscles and joints.
🥗
Engage in regular low-impact exercises like walking or swimming, as advised by your doctor.
😴
Practice good posture and body mechanics to prevent muscle strain.
💧
Apply heat or cold packs to tense muscles for additional relief.
🧘
Get adequate sleep to help your body recover.
🌞
Manage stress with relaxation techniques like deep breathing or meditation.

🏋️ Exercise Considerations

While taking this medicine, you may feel drowsy or dizzy. Avoid activities that require alertness, such as driving or operating machinery. If you exercise, do so with caution and avoid heavy lifting or high-impact activities that could worsen your muscle spasms. Follow your doctor's or physical therapist's advice on safe exercises.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits, vegetables, and whole grains.
Include anti-inflammatory foods like fatty fish, nuts, and olive oil.
Stay well hydrated by drinking plenty of water.
Limit processed foods, sugary drinks, and excessive caffeine.
Avoid alcohol completely while taking this medicine.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to work, drive, or operate machinery. Avoid these activities until you know how the medicine affects you. If your job requires alertness, talk to your doctor about adjusting your dose or timing. You may need to take time off or modify your tasks temporarily.

🛑 When to Stop This Medicine

Stop taking this medicine after the prescribed short-term course, usually 2-3 weeks, unless your doctor advises otherwise. If you experience serious side effects, stop and seek medical help immediately. Do not stop suddenly if you have been taking it for a long time; consult your doctor for a tapering plan.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. It may also cause liver problems and blood disorders in rare cases. It is not recommended for long-term use. If you need treatment for more than 2-3 weeks, your doctor should reassess your condition and consider other options.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help strengthen muscles, improve flexibility, and reduce pain without medication.

Evidence: Well-established
Heat or cold therapy

Applying heat or cold packs can relax muscles and relieve pain.

Evidence: Well-established
Massage therapy

May help relieve muscle tension and improve circulation.

Evidence: Limited
Acupuncture

Some people find relief from muscle pain with acupuncture.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while taking this medicine, but inform your healthcare provider about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue taking it at the same intervals as prescribed, but consult your doctor if you are unsure. Check local customs regulations for controlled medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute lower back pain and muscle spasm
Ravi was prescribed this medicine for short-term relief of back spasm. He took it as directed with food and avoided alcohol. Within a few days, his muscle tightness eased, and he was able to start physical therapy. He stopped the medicine after two weeks as advised and had no withdrawal symptoms.
💡 Lesson: Short-term use as prescribed, along with physical therapy, can provide effective relief without dependence.
👤 A 60-year-old woman with muscle spasms after a fall
Mrs. Sharma started this medicine but felt very drowsy and dizzy. She spoke to her doctor, who reduced her dose. She was advised not to drive and to take it only at bedtime. Her spasms improved, and she avoided falls by taking precautions.
💡 Lesson: Elderly patients may need a lower dose and should be cautious about drowsiness and falls.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour after you take it.

Q: How long can I take this medicine?

A: It is usually prescribed for short-term use, up to 2-3 weeks. Longer use should only be under your doctor's supervision.

Q: Can I stop this medicine suddenly?

A: If you have been taking it for more than a few weeks, do not stop suddenly. Talk to your doctor about tapering to avoid withdrawal symptoms.

Q: Is it safe to take with other painkillers?

A: It can be taken with some painkillers like paracetamol, but always check with your doctor or pharmacist first, especially if you take opioids or sedatives.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is this medicine addictive?
  • How long does it stay in my system?

🔄 Substitutes for korisuma tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take for months.
    Fact: This medicine is only for short-term use, usually up to 2-3 weeks, because it can cause dependence and withdrawal.
  • Myth: This medicine can be taken with alcohol.
    Fact: Alcohol increases the sedative effects and can cause dangerous drowsiness and breathing problems.
  • Myth: This medicine is a painkiller like paracetamol.
    Fact: This medicine is a muscle relaxant, not a general painkiller. It works on the brain and spinal cord to relax muscles.

🔄 Alternative Options

Generic Alternatives

  • Carisoprodol 350 mg tablet

Brand Alternatives

  • Korisuma tablet

📊 Comparison with Similar Medicines

[{"medicine":"Carisoprodol","class":"Centrally acting muscle relaxant","common_use":"Muscle spasms","sedation":"High","dependence":"Yes"},{"medicine":"Cyclobenzaprine","class":"Centrally acting muscle relaxant","common_use":"Muscle spasms","sedation":"Moderate","dependence":"Low"},{"medicine":"Chlorzoxazone","class":"Centrally acting muscle relaxant","common_use":"Muscle spasms","sedation":"Moderate","dependence":"Low"}]

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