abalin-sr tablet - Pregabalin (75mg) medicine

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🏭 Holy Evolution Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, or throat
  • Difficulty breathing or shortness of breath
  • Suicidal thoughts or self-harm
  • Severe dizziness or fainting
  • Unusual muscle pain or weakness
  • Dark or decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is abalin-sr tablet used for?

This medicine is a prescription medication used to treat neuropathic pain, fibromyalgia, and partial-onset seizures. It works by reducing the release of certain neurotransmitters in the brain.

  • Generic Name: Pregabalin (75mg)
  • Manufacturer: Holy Evolution Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 abalin-sr tablet के बारे में (Hindi Summary)

उपयोग: यह दवा न्यूरोपैथिक दर्द, फाइब्रोमायल्जिया और आंशिक दौरे के इलाज के लिए इस्तेमाल की जाती है। यह तंत्रिका कोशिकाओं में कैल्शियम चैनलों से जुड़कर दर्द संकेतों को कम करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, नींद आना, मुँह सूखना, वजन बढ़ना और हाथ-पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई और आत्मघाती विचार हो सकते हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें। शराब से बचें। गाड़ी चलाते समय सावधानी बरतें। गुर्दे की समस्या हो तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 abalin-sr tablet Uses & Benefits

[{"condition":"Diabetic peripheral neuropathy","description":"This medicine is used to relieve nerve pain associated with diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"This medicine helps reduce pain that persists after a shingles infection.","evidence":"Well-established"},{"condition":"Fibromyalgia","description":"This medicine is prescribed to manage widespread muscle pain and fatigue.","evidence":"Well-established"},{"condition":"Partial-onset seizures","description":"This medicine is used as an add-on treatment for partial seizures in adults.","evidence":"Well-established"},{"condition":"Generalized anxiety disorder","description":"This medicine may be used in some countries for anxiety, but it is not approved for this use in all regions.","evidence":"Limited"}]

Off-label uses: [{"condition":"Chronic low back pain","description":"Sometimes prescribed off-label for chronic back pain with a neuropathic component.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally used off-label to prevent migraines, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Neuropathic pain

Also treats: Epilepsy, Fibromyalgia, Generalized anxiety disorder

📋 Drug Information

Generic Name(s)Pregabalin (75mg)
Brand Nameabalin-sr tablet
ManufacturerHoly Evolution Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAlpha 2 delta ligands (AED)
Route of AdministrationOral
StorageStore at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Avoid driving or operating machinery until you know how this medicine affects you.
3
Do not stop this medicine abruptly; your doctor will taper the dose gradually.
4
Inform your doctor if you experience swelling in your hands or feet.
5
Report any mood changes or suicidal thoughts immediately.
6
Use effective contraception if you are of childbearing age and taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Nerve pain
This medicine is commonly prescribed for this.
Likely Use
Seizures
This medicine is used as an add-on treatment for partial seizures.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration. The bioavailability is approximately 90% and is not affected by food.
DistributionThis medicine does not bind to plasma proteins and has a volume of distribution of approximately 0.5 L/kg.
Protein BindingThis medicine does not bind to plasma proteins.
MetabolismThis medicine undergoes negligible metabolism in humans. It is excreted largely unchanged in the urine.
Half-LifeThe elimination half-life of this medicine is approximately 6.3 hours.
ExcretionThis medicine is primarily excreted unchanged in the urine, with about 90% of the dose recovered in urine as unchanged drug.
BioavailabilityThe oral bioavailability of this medicine is approximately 90%.
Onset of ActionThe onset of action for pain relief may occur within a few days to weeks, depending on the condition being treated.
Peak Plasma TimePeak plasma concentrations are reached within 1.5 hours after oral administration.
Duration of ActionThe duration of action is not well established, but the effects are generally dose-dependent and may last for several hours.

How It Works

This medicine works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the influx of calcium into nerve cells, which in turn decreases the release of several neurotransmitters, including glutamate, norepinephrine, and substance P. These neurotransmitters are involved in transmitting pain signals and in seizure activity. By reducing their release, this medicine helps to alleviate neuropathic pain and reduce the frequency of seizures.

Mechanism Steps

1
Binding to calcium channels: This medicine binds to the alpha-2-delta subunit of voltage-gated calcium channels in the brain and spinal cord.
2
Reduced calcium influx: This binding reduces the influx of calcium into presynaptic nerve terminals.
3
Decreased neurotransmitter release: As a result, the release of excitatory neurotransmitters such as glutamate and substance P is reduced.
4
Pain relief and seizure control: The decreased neurotransmitter release leads to reduced pain signaling and decreased seizure activity.

💡 How to Take abalin-sr tablet

Strength: Capsule: 75 mg

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3You can take it with or without food.
4Do not crush, chew, or break the capsule.
5Take it at the same time each day to maintain consistent levels.

Dosage Information

Adult DosageThe usual starting dose for neuropathic pain is 75 mg twice daily or 50 mg three times daily. The dose may be increased gradually up to a maximum of 600 mg per day in divided doses, depending on the condition and response. For seizures, the starting dose is 75 mg twice daily, which may be increased to a maximum of 600 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function. Dose should be adjusted based on creatinine clearance.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance 30-60 mL/min, the dose should be reduced by 50%. For creatinine clearance 15-30 mL/min, the dose should be reduced by 75%. For creatinine clearance less than 15 mL/min, the dose should be reduced to 25% of the normal dose.
Hepatic ImpairmentNo dose adjustment is required for patients with hepatic impairment.
Maximum Daily Dose600 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not affect absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of abalin-sr tablet

✅ Common Side Effects

Dizziness (Common (1-10%))
Avoid driving or operating machinery until you know how this medicine affects you. If dizziness persists, consult your doctor.
Drowsiness (Common (1-10%))
Take the medicine at bedtime if it makes you sleepy during the day. Avoid alcohol.
Dry mouth (Common (1-10%))
Sip water frequently or chew sugar-free gum. Consult your doctor if it becomes bothersome.
Weight gain (Common (1-10%))
Monitor your weight and maintain a healthy diet. Consult your doctor if weight gain is significant.
Peripheral edema (Common (1-10%))
Elevate your legs when sitting. Consult your doctor if swelling is severe or persistent.

🚨 Serious Side Effects

Angioedema (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, or tongue.
Suicidal thoughts (Rare (<0.1%))
Contact your doctor immediately if you have thoughts of harming yourself.
Respiratory depression (Rare (<0.1%))
Seek emergency help if you have difficulty breathing, especially if you are taking other sedatives.

⚠️ Rare Side Effects

Rhabdomyolysis
Seek immediate medical attention if you experience muscle pain, weakness, or dark urine.
Heart failure
Report symptoms such as shortness of breath, swelling, or fatigue to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Opioids Major
Benzodiazepines Major
Alcohol Moderate
Antihypertensives Moderate
Antacids Minor

🚨 Major Interactions

  • Opioids
  • Benzodiazepines

⚡ Moderate Interactions

  • Alcohol
  • Antihypertensives

🍷 Alcohol Interaction

Alcohol can increase the sedative and dizzying effects of this medicine. It is recommended to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to pregabalin or any component of the formulation."]

⚠️ Warnings & Precautions

["May cause dizziness and drowsiness; avoid driving or operating machinery until you know how it affects you.","May increase the risk of suicidal thoughts; monitor for mood changes.","Use with caution in patients with renal impairment; dose adjustment may be needed.","May cause peripheral edema; use with caution in patients with heart failure.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","May cause respiratory depression when used with other CNS depressants."]

🤱 Lactation Safety

This medicine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. There is no specific antidote for pregabalin overdose. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. Be cautious when driving or operating machinery until you know how this medicine affects you. Inform your doctor if you have kidney problems, as the dose may need to be adjusted. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to experience dizziness, drowsiness, and peripheral edema. Dose adjustment based on renal function is often necessary.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine should be used during pregnancy only if the potential benefit justifies the risk. Effective contraception is recommended for women of childbearing age.

🏥 Post-Surgery Considerations

This medicine may be continued before and after surgery, but inform your surgeon and anesthesiologist. It may interact with anesthetic agents and increase sedation.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain medications used in dental procedures and increase drowsiness.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on your joints and nerves.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice relaxation techniques to manage stress and anxiety.
💧
Get adequate sleep to help your body recover.
🧘
Avoid alcohol and recreational drugs.

🏋️ Exercise Considerations

This medicine may cause dizziness and drowsiness. Avoid activities that require mental alertness until you know how it affects you. Gentle exercise is encouraged but avoid high-risk activities.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include omega-3 fatty acids from fish or flaxseed.
Limit processed foods and added sugars.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. It is important to assess your response before engaging in such activities. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or if your doctor decides to discontinue, the dose will be tapered gradually to prevent withdrawal symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to weight gain, peripheral edema, and dependence. Regular monitoring of renal function and mental health is recommended. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help improve strength and reduce pain.

Evidence: Well-established
Cognitive behavioral therapy

Helps manage chronic pain and anxiety.

Evidence: Well-established
Acupuncture

May provide pain relief for some patients.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, adjust your dosing schedule gradually in consultation with your doctor. Check local customs regulations for controlled substances.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with diabetic nerve pain
He started this medicine as prescribed for his burning foot pain. After a few weeks, he noticed significant relief and was able to sleep better. He experienced mild dizziness initially, which went away after a few days.
💡 Lesson: Consistent use and patience are key; side effects often diminish over time.
👤 A 40-year-old woman with fibromyalgia
She was prescribed this medicine for widespread muscle pain. She found that taking it at bedtime helped with her sleep and reduced her pain during the day. She also incorporated gentle exercise and stress management techniques.
💡 Lesson: Combining medication with lifestyle changes can improve overall outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may start to relieve pain within a few days, but it may take several weeks to achieve full effect.

Q: Can I stop taking this medicine suddenly?

A: No, stopping suddenly can cause withdrawal symptoms. Your doctor will gradually reduce the dose.

Q: Is this medicine safe during pregnancy?

A: It should be used during pregnancy only if clearly needed. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for abalin-sr tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a painkiller like ibuprofen.
    Fact: This medicine is not a typical painkiller; it works on the nervous system to reduce nerve pain.
  • Myth: This medicine is addictive.
    Fact: This medicine has a low potential for abuse, but it can cause dependence if taken for a long time. It should be tapered gradually.

🔄 Alternative Options

Generic Alternatives

  • Pregabalin 75 mg capsule

Brand Alternatives

  • Lyrica 75 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Pregabalin","class":"Anticonvulsant","primary_use":"Neuropathic pain, seizures","common_side_effects":"Dizziness, drowsiness"},{"medicine":"Gabapentin","class":"Anticonvulsant","primary_use":"Neuropathic pain, seizures","common_side_effects":"Dizziness, drowsiness"},{"medicine":"Duloxetine","class":"SNRI","primary_use":"Neuropathic pain, depression","common_side_effects":"Nausea, dry mouth"}]

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