koldwin tablet - Caffeine (30mg) + Paracetamol (325mg) medicine

Burdy AC Tablet: Complete Medicine Guide

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🏭 Surewin Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for paracetamol and caffeine combination in pain relief.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes
  • Dark urine or pale stools
  • Severe abdominal pain
  • Blood in vomit or stool
  • Difficulty breathing or swelling of face, lips, or throat
  • Unusual bleeding or bruising
  • Persistent high fever

If experiencing severe symptoms, call emergency services immediately.

What is koldwin tablet used for?

This medicine is a combination of paracetamol and caffeine used for relief of mild to moderate pain and fever. It works by reducing pain signals in the brain and enhancing the pain-relieving effect of paracetamol.

  • Generic Name: Caffeine (30mg) + Paracetamol (325mg)
  • Manufacturer: Surewin Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 koldwin tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और कैफीन का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, माइग्रेन, दांत दर्द, मांसपेशियों में दर्द और मासिक धर्म के दर्द में राहत देती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट में असुविधा, बेचैनी, अनिद्रा और घबराहट शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन जिगर की क्षति हो सकती है, खासकर अधिक मात्रा में लेने पर।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अधिक मात्रा में न लें। शराब का सेवन न करें। पैरासिटामोल युक्त अन्य दवाओं के साथ न लें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 koldwin tablet Uses & Benefits

[{"condition":"Tension headache","description":"Relieves mild to moderate headache pain by combined analgesic effect of paracetamol and caffeine.","evidence":"Well-established"},{"condition":"Migraine","description":"Used for acute treatment of migraine attacks; caffeine enhances paracetamol's efficacy.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever through paracetamol's antipyretic action.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides temporary relief from toothache and post-dental procedure pain.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Eases mild to moderate muscle aches and joint pain.","evidence":"Moderate"},{"condition":"Menstrual cramps","description":"Alleviates dysmenorrhea pain.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used as part of multimodal analgesia, but not a primary choice.","evidence":"Limited"},{"condition":"Cancer pain","description":"May be used as adjunct for mild cancer pain, but not for severe pain.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Migraine, Dental pain, Musculoskeletal pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Caffeine (30mg) + Paracetamol (325mg)
Brand Namekoldwin tablet
ManufacturerSurewin Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from direct sunlight, moisture, and heat. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose; high doses can cause liver damage.
3
Avoid alcohol while taking this medicine.
4
Do not take other paracetamol-containing products simultaneously.
5
Consult your doctor if pain persists beyond 5 days or fever beyond 3 days.
6
Limit caffeine intake from other sources to avoid insomnia and palpitations.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly used for headache relief.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
❌
Chronic joint pain
This medicine is not primarily for chronic joint pain; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Caffeine is also rapidly absorbed. Peak plasma concentrations occur within 30-60 minutes for paracetamol and 15-45 minutes for caffeine.
DistributionParacetamol distributes widely into body tissues, with a volume of distribution of about 0.9 L/kg. Caffeine distributes throughout body water, with a volume of distribution of about 0.6 L/kg. Both cross the placenta and are excreted in breast milk.
Protein BindingParacetamol: 10-25% bound to plasma proteins. Caffeine: about 15-25% bound to plasma proteins.
MetabolismParacetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction via CYP2E1 to N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione. Caffeine is metabolized in the liver by CYP1A2 to paraxanthine, theobromine, and theophylline.
Half-LifeParacetamol: 2-3 hours. Caffeine: 3-5 hours.
ExcretionParacetamol metabolites are excreted primarily in urine. Caffeine metabolites are excreted in urine, with less than 2% excreted unchanged.
BioavailabilityParacetamol: 80-100% oral bioavailability. Caffeine: nearly 100% oral bioavailability.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeParacetamol: 30-60 minutes. Caffeine: 15-45 minutes.
Duration of ActionPain relief lasts approximately 4-6 hours.

How It Works

Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, likely through COX-3 inhibition and descending serotonergic pathways, leading to reduced pain perception and fever. Caffeine is a methylxanthine that blocks adenosine receptors, causing vasoconstriction and enhancing the analgesic effect of paracetamol by increasing its bioavailability and modulating pain signaling.

Mechanism Steps

1
Paracetamol central COX inhibition: Paracetamol inhibits prostaglandin synthesis in the brain and spinal cord, reducing pain and fever.
2
Caffeine adenosine receptor blockade: Caffeine blocks adenosine A1 and A2A receptors, leading to vasoconstriction and increased neuronal activity.
3
Enhanced analgesia: Caffeine increases the bioavailability and central effects of paracetamol, resulting in stronger pain relief.

💡 How to Take koldwin tablet

Strength: Tablet containing Caffeine 30 mg and Paracetamol 325 mg.

1Take this medicine orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food or milk to reduce stomach upset.
4Follow the prescribed dose and frequency.
5Do not exceed the maximum daily dose.

Dosage Information

Adult DosageThe usual adult dose is 1 to 2 tablets taken orally every 4 to 6 hours as needed for pain or fever, not exceeding 6 tablets in 24 hours. The maximum daily dose of paracetamol should not exceed 3,000 mg from all sources. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of caffeine and paracetamol. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentIn patients with mild to moderate renal impairment, dose reduction or increased dosing interval may be necessary. In severe renal impairment (creatinine clearance <30 mL/min), use with caution and consult a doctor. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, reduce dose and limit duration of use. In severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily DoseMaximum 6 tablets in 24 hours, providing 1,950 mg paracetamol and 180 mg caffeine. Do not exceed 3,000 mg paracetamol from all sources per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or snacks
Reduces stomach upset.
Grapefruit juice
Avoid large amounts
May increase caffeine levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of koldwin tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset. Consult doctor if persistent.
Insomnia (Common (5-10%))
Avoid taking close to bedtime. Limit caffeine intake from other sources.
Restlessness (Common (5-10%))
Usually resolves as body adjusts. Reduce dose if bothersome after consulting doctor.
Stomach discomfort (Common (5-10%))
Take with a meal or snack. Consult doctor if severe.

🚨 Serious Side Effects

Severe liver injury (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, throat, or difficulty breathing.
Blood disorders (thrombocytopenia, leukopenia) (Very rare (<0.01%))
Report unusual bleeding, bruising, or persistent fever to your doctor immediately.

⚠️ Rare Side Effects

Skin rash
Discontinue and consult doctor if rash develops.
Hypokalemia
Report muscle weakness or cramps to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Fluconazole Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other paracetamol-containing products

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, rifampicin
  • Fluconazole, ketoconazole

🍷 Alcohol Interaction

Avoid alcohol consumption while taking this medicine. Alcohol increases the risk of paracetamol-induced liver damage and may worsen caffeine-related side effects such as insomnia and palpitations.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to paracetamol or caffeine","Severe hepatic impairment or active liver disease","Severe renal impairment","Children under 12 years of age","Chronic alcoholism"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose; high doses can cause liver damage.","Avoid alcohol during treatment.","Do not use with other paracetamol-containing products.","Use with caution in patients with liver or kidney disease.","May cause insomnia; avoid taking close to bedtime.","Consult doctor if pain persists beyond 5 days or fever beyond 3 days.","Not recommended for children under 12 years without medical advice.","Pregnant women should limit caffeine intake from all sources."]

🤱 Lactation Safety

Paracetamol and caffeine are excreted in breast milk in small amounts. Short-term use at recommended doses is generally considered safe, but consult your doctor. Avoid high doses of caffeine to prevent infant irritability.

💊 Overdose Management

Overdose of paracetamol can cause severe liver damage, which may be delayed. Symptoms of overdose include nausea, vomiting, abdominal pain, and sweating. If overdose is suspected, seek emergency medical help immediately. Treatment with N-acetylcysteine is most effective when given within 8-10 hours of ingestion. Caffeine overdose may cause palpitations, tremors, and insomnia; supportive care is usually sufficient.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose or duration. Avoid consuming alcohol while taking this medicine as it increases the risk of liver damage. Do not take other products containing paracetamol simultaneously to prevent overdose. Inform your doctor if you have liver or kidney disease, or if you are pregnant or breastfeeding. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to caffeine and paracetamol. Use the lowest effective dose and monitor for side effects. Consult a doctor for dose adjustments.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Paracetamol is generally considered safe, but limit caffeine intake.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain relief, but follow your surgeon's instructions. Do not exceed the recommended dose.

🦷 Dental Procedures

This medicine can be taken for dental pain before or after procedures. Inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Stay hydrated throughout the day.
😴
Get adequate sleep to help manage pain.
💧
Practice relaxation techniques to reduce tension headaches.
🧘
Limit caffeine intake from other sources.

🏋️ Exercise Considerations

Moderate exercise is generally safe while taking this medicine. Avoid strenuous activities if you feel dizzy or fatigued. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include anti-inflammatory foods like fruits and vegetables.
Reduce processed food intake.
Stay well hydrated.
Limit alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause insomnia or restlessness due to caffeine. Avoid driving or operating machinery if you feel drowsy or dizzy. It is generally safe for most people to continue their daily activities.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if pain persists beyond 5 days, fever lasts more than 3 days, or if you experience any serious side effects. Do not stop prescribed medication without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be avoided unless prescribed. Prolonged high-dose paracetamol can cause liver damage. Regular monitoring of liver function may be needed. Consult your doctor for alternative treatments if pain persists.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help manage chronic pain conditions.

Evidence: Well-established
Relaxation techniques

Useful for tension headaches and stress-related pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever, but consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. When traveling across time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with tension headaches
She took this medicine as prescribed for her headaches. She noticed relief within 30 minutes. She was advised to take it with food to avoid stomach upset and to limit caffeine intake.
💡 Lesson: Taking with food improves tolerability, and limiting additional caffeine prevents side effects.
👤 A 50-year-old man with dental pain
He used this medicine for toothache before his dental appointment. It provided effective pain relief, but he was cautioned not to exceed the dose due to risk of liver damage.
💡 Lesson: Short-term use at recommended doses is safe and effective for acute pain.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe during pregnancy?

A: Paracetamol is generally safe, but caffeine should be limited. Consult your doctor before use.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for koldwin tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It is safe to take unlimited paracetamol.
    Fact: Exceeding the recommended dose can cause severe liver damage.
  • Myth: Caffeine in painkillers is harmful.
    Fact: Caffeine in small doses enhances pain relief and is safe for most people.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol 325 mg + Caffeine 30 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Burdy AC Tablet","composition":"Paracetamol 325 mg + Caffeine 30 mg","uses":"Pain and fever","onset":"30-60 minutes"},{"medicine":"Paracetamol 500 mg","composition":"Paracetamol 500 mg","uses":"Pain and fever","onset":"30-60 minutes"},{"medicine":"Ibuprofen 200 mg","composition":"Ibuprofen 200 mg","uses":"Pain, fever, inflammation","onset":"30-60 minutes"}]

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