Ambro S 1.25mg/15mg Syrup: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or worsening of asthma symptoms after taking the medicine.
- Chest pain, palpitations, or irregular heartbeat.
- Severe allergic reaction: rash, itching, swelling of face, lips, or throat.
- Severe dizziness or fainting.
- Muscle weakness or cramps (possible low potassium).
- Yellowing of eyes or skin (jaundice).
- Blood in cough or vomit.
If experiencing severe symptoms, call emergency services immediately.
What is kafno syrup used for?
This medicine is a combination syrup containing terbutaline (a bronchodilator) and ambroxol (a mucolytic). It is used to relieve cough with thick mucus and to ease breathing in conditions like bronchitis, COPD, and asthma. It works by relaxing airway muscles and thinning mucus. It should be taken only as prescribed by a doctor.
- Generic Name: Terbutaline (1.25mg) + Ambroxol (15mg)
- Manufacturer: Bio-Med Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kafno syrup के बारे में (Hindi Summary)
उपयोग: यह दवा टर्ब्यूटालीन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस लेने में कठिनाई के इलाज के लिए किया जाता है। यह ब्रोंकाइटिस, सीओपीडी और अस्थमा जैसी स्थितियों में राहत देती है। यह वायुमार्ग की मांसपेशियों को आराम देकर और बलगम को पतला करके काम करती है। इसका उपयोग डॉक्टर के परामर्श के अनुसार ही करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, सिरदर्द, चक्कर आना, धड़कन बढ़ना और कंपन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, अनियमित धड़कन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाला कप या चम्मच इस्तेमाल करें। चक्कर आने पर वाहन न चलाएं। दवा को ठंडी और सूखी जगह पर रखें।
💊 kafno syrup Uses & Benefits
[{"condition":"Acute bronchitis with productive cough","description":"Helps loosen mucus and relax airways, making cough more productive and easing breathing.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) exacerbation","description":"Provides symptomatic relief by bronchodilation and mucus clearance.","evidence":"Established"},{"condition":"Asthma (adjunctive therapy)","description":"Used as add-on therapy for acute bronchospasm, but not for long-term control.","evidence":"Established"},{"condition":"Cough with thick mucus","description":"Ambroxol thins mucus, making it easier to cough out.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of respiratory distress syndrome in premature infants","description":"Ambroxol has been studied off-label for this purpose, but not with this combination.","evidence":"Limited"}]
Primary treatment for: Productive cough associated with bronchitis
📋 Drug Information
| Generic Name(s) | Terbutaline (1.25mg) + Ambroxol (15mg) |
| Brand Name | kafno syrup |
| Manufacturer | Bio-Med Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Terbutaline is a selective beta-2 adrenergic agonist that binds to beta-2 receptors on bronchial smooth muscle, leading to relaxation and bronchodilation. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and promotes ciliary clearance. Together, they improve airflow and ease cough.
Mechanism Steps
💡 How to Take kafno syrup
Strength: Each 5 mL contains Terbutaline 1.25 mg and Ambroxol 15 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 mL (1-2 teaspoons) two to three times a day, or as directed by your physician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of terbutaline, especially cardiac effects. Use with caution and lower doses may be considered. Individualize by a clinician. |
| Renal Impairment | Use with caution in renal impairment. Dose adjustment may be needed. Consult your doctor. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed 30 mL (6 teaspoons) in adults, unless otherwise prescribed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kafno syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| Furosemide | Moderate | |
| Digoxin | Moderate | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Corticosteroids | Moderate | |
| Theophylline | Moderate | |
| Other beta-2 agonists | Moderate | |
| Anticholinergics | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase dizziness and drowsiness. Avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to terbutaline, ambroxol, or any component","Severe cardiac disease","Hypertrophic obstructive cardiomyopathy","Thyrotoxicosis","Children under 2 years (unless directed by specialist)"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disorders, including coronary insufficiency and hypertension.","May cause tremors and nervousness; avoid driving if affected.","Use with caution in diabetes mellitus; may increase blood glucose.","Use with caution in hyperthyroidism.","Not for prolonged use without medical supervision.","Do not exceed recommended dose."]
🤱 Lactation Safety
Terbutaline is excreted in breast milk in small amounts. Ambroxol is also likely excreted. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Symptoms of overdose include severe tachycardia, palpitations, tremor, nausea, and vomiting. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Shake the bottle well before each use. Use a proper measuring cup or spoon to ensure accurate dosing. Avoid driving or operating heavy machinery if you feel dizzy or shaky. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver/kidney disease. Do not use this medicine for a prolonged period without medical advice. Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture. Do not use if the syrup is discolored or has particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to cardiac side effects like tachycardia and arrhythmias. Use with caution and monitor heart rate. Lower doses may be needed.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. Terbutaline is FDA category C; ambroxol safety is not established. Use only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine, as it may interact with anesthetic agents and affect heart rate.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may cause dry mouth or interact with local anesthetics containing epinephrine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy, shaky, or have a rapid heartbeat. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or tremors, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to rest and recover.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, or if you experience severe side effects. Do not stop abruptly if you have been on it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of terbutaline may lead to tolerance and reduced effectiveness. Prolonged use of ambroxol is generally well tolerated but monitoring of liver function may be advisable. This medicine is usually prescribed for short-term relief. Do not use for extended periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and ease breathing.
Evidence: Well-establishedTechniques to clear mucus from airways.
Evidence: EstablishedMay help with congestion.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Ensure vaccinations like influenza and pneumococcal are up to date, especially if you have chronic respiratory conditions. This medicine does not interact with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Terbutaline starts working within 30 minutes, while ambroxol's effect on mucus may take a few hours.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: Consult a pediatrician. Dosing in children is not established from available information.
A: Take it as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for kafno syrup
View AllAlternative brands with exact same active ingredient:
-
tercuf syrupG-Nine Formulations Pvt Ltd ₹28.59 15.3% CHEAPER
-
Terlin A ExpectorantHinglaj Laboratories ₹32.00 5.2% CHEAPER
-
broxtid syrupAveon Healthcare & Pharma Pvt Ltd ₹37.00 9.6% COSTLIER
-
historil syrupAcuition Pharmaceutical ₹37.50 11.1% COSTLIER
-
cosox syrupAelida Healthcare ₹42.19 25% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of cough.
Fact: It is specifically for cough with thick mucus and breathing difficulty. It is not effective for dry cough or cough due to allergies. - Myth: It is safe to take this medicine for a long time.
Fact: Prolonged use without medical supervision can lead to side effects. It is usually prescribed for short-term relief. - Myth: More syrup means faster relief.
Fact: Taking more than the prescribed dose can cause serious side effects like rapid heartbeat and tremors. Always follow the prescribed dose.
🔄 Alternative Options
Generic Alternatives
- Terbutaline + Ambroxol syrup (various manufacturers)
Brand Alternatives
- Ambro S 1.25mg/15mg syrup (Galpha Laboratories Ltd)