jevacain suspension - Oxetacaine (10mg) + Aluminium Hydroxide (291mg) medicine

Antarich Oral Suspension Sugar Free: Complete Medicine Guide

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🏭 Esma Formulations 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of acid-related disorders.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain
  • Difficulty breathing or swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Confusion or muscle weakness (signs of aluminium toxicity)

If experiencing severe symptoms, call emergency services immediately.

What is jevacain suspension used for?

This medicine is a combination of oxetacaine and aluminium hydroxide used to treat heartburn, gastritis, and acid reflux. It works by numbing the stomach lining and neutralising acid.

  • Generic Name: Oxetacaine (10mg) + Aluminium Hydroxide (291mg)
  • Manufacturer: Esma Formulations
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 jevacain suspension के बारे में (Hindi Summary)

उपयोग: यह दवा ऑक्सेटाकेन और एल्युमिनियम हाइड्रॉक्साइड का संयोजन है, जिसका उपयोग एसिडिटी, गैस्ट्रिटिस, हार्टबर्न और पेट के अल्सर से होने वाले दर्द और जलन को कम करने के लिए किया जाता है। ऑक्सेटाकेन पेट और अन्नप्रणाली की परत को सुन्न करके दर्द से राहत देता है, जबकि एल्युमिनियम हाइड्रॉक्साइड पेट के एसिड को न्यूट्रलाइज़ करता है। यह शुगर-फ्री फॉर्मूलेशन है, इसलिए मधुमेह रोगी भी इसका उपयोग कर सकते हैं।

साइड इफेक्ट्स: आमतौर पर यह दवा सही तरीके से लेने पर अच्छी तरह सहन की जाती है। कुछ लोगों को कब्ज, मतली, या मुँह में चॉकी स्वाद का अनुभव हो सकता है। दुर्लभ मामलों में एलर्जी, त्वचा पर चकत्ते, या सूजन हो सकती है। गुर्दे की बीमारी वाले लोगों में लंबे समय तक उपयोग से एल्युमिनियम जमा हो सकता है, जिससे हड्डियों में दर्द, मांसपेशियों में कमजोरी या भ्रम हो सकता है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं। दवा को मापने के लिए दिए गए कप या चम्मच का ही उपयोग करें। इसे भोजन से पहले या सोने से पहले लेना बेहतर होता है। अन्य दवाओं के साथ लेने से पहले कम से कम 2 घंटे का अंतराल रखें। गुर्दे की बीमारी होने पर डॉक्टर की सलाह के बिना इसका उपयोग न करें। बच्चों को डॉक्टर की सलाह के बिना न दें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 jevacain suspension Uses & Benefits

[{"condition":"Gastritis","description":"Provides symptomatic relief from pain and burning in the stomach lining.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Helps relieve heartburn and acid regurgitation by neutralising acid and numbing the oesophagus.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Used as an adjunct to reduce pain and protect the ulcerated mucosa.","evidence":"Well-established"},{"condition":"Dyspepsia","description":"Relieves upper abdominal discomfort associated with excess acid.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Mucositis due to chemotherapy or radiotherapy","description":"Sometimes used off-label for symptomatic relief of oral and oesophageal mucositis.","evidence":"Limited"}]

Primary treatment for: Gastritis

Also treats: Gastroesophageal reflux disease, Peptic ulcer disease, Dyspepsia

📋 Drug Information

Generic Name(s)Oxetacaine (10mg) + Aluminium Hydroxide (291mg)
Brand Namejevacain suspension
ManufacturerEsma Formulations
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine 30 minutes before meals for best effect.
2
Shake the bottle well before each use to ensure proper mixing.
3
Separate this medicine from other medications by at least 2 hours.
4
Do not use for more than 7 days without consulting your doctor.
5
If you have kidney disease, inform your doctor before using this medicine.
6
Report any persistent constipation or abdominal pain to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
✅
Epigastric pain
This medicine can help relieve this symptom.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOxetacaine is poorly absorbed from the gastrointestinal tract; its action is primarily local. Aluminium hydroxide is minimally absorbed; small amounts of aluminium may be absorbed and excreted by the kidneys.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismOxetacaine is likely metabolised in the liver, but specific data are not established. Aluminium hydroxide is not metabolised.
Half-LifeNot established from the available information.
ExcretionAbsorbed aluminium is excreted primarily in the urine. Unabsorbed aluminium is excreted in the faeces. Oxetacaine and its metabolites are likely excreted in urine and faeces, but specific data are not established.
BioavailabilityNot established from the available information.
Onset of ActionThe local anaesthetic effect of oxetacaine begins within a few minutes of contact with the mucosa. The antacid effect of aluminium hydroxide also starts within minutes.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe anaesthetic effect may last for approximately 20-30 minutes. The antacid effect lasts until the stomach empties, typically 1-2 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Oxetacaine is a local anaesthetic that reversibly blocks sodium channels in nerve endings, reducing the transmission of pain signals from the irritated mucosa of the oesophagus and stomach. Aluminium hydroxide is an antacid that neutralises gastric acid by chemical reaction, forming aluminium chloride and water, thereby raising the pH of the stomach contents. This reduces acid irritation and helps protect the mucosal lining. The combination provides both rapid pain relief and acid neutralisation.

Mechanism Steps

1
Local anaesthetic action: Oxetacaine blocks sodium channels in the nerve endings of the gastrointestinal mucosa, preventing the generation and conduction of pain impulses.
2
Acid neutralisation: Aluminium hydroxide reacts with hydrochloric acid in the stomach to form aluminium chloride and water, raising the gastric pH.
3
Mucosal protection: By reducing acid and numbing the surface, the medicine helps protect the irritated mucosa from further damage and provides symptomatic relief.

💡 How to Take jevacain suspension

Strength: Each 5 mL contains Oxetacaine 10 mg and Aluminium Hydroxide 291 mg.

1Shake the bottle well before each use.
2Measure the prescribed dose using the provided measuring cup or spoon.
3Take the medicine orally, preferably 30 minutes before meals or as directed by your doctor.
4Do not dilute with water unless instructed.
5Rinse your mouth after taking to remove any chalky taste.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL of the suspension taken three to four times daily, preferably before meals and at bedtime, or as directed by your doctor. The dose may vary depending on the condition being treated and the severity of symptoms. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to side effects, especially constipation and aluminium accumulation. Use with caution and monitor renal function.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Consult your doctor.
Hepatic ImpairmentNo specific dosage adjustment is established for hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum daily dose should not exceed 40 mL of the suspension in divided doses, unless otherwise directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take 30 minutes before meals
Enhances antacid effect and reduces stomach upset.
Citrus fruits
Avoid large amounts
May increase aluminium absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of jevacain suspension

✅ Common Side Effects

Constipation (Common (5-10%))
Increase dietary fibre and fluid intake. Consult your doctor if it persists.
Nausea (Common (5-10%))
Take with food or milk if advised. Usually resolves on its own.
Chalky taste (Common (5-10%))
Rinse mouth after taking. Usually not bothersome.

🚨 Serious Side Effects

Aluminium accumulation (in renal impairment) (Rare (<0.1%))
Seek medical attention if you experience bone pain, muscle weakness, or confusion.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical help if you develop rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hypophosphataemia
Prolonged high-dose use may cause low phosphate levels. Monitor if on long-term therapy.
Encephalopathy (aluminium toxicity)
Report confusion, seizures, or personality changes immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Fluoroquinolones Major
Iron salts Moderate
Digoxin Moderate
Ketoconazole Moderate

🚨 Major Interactions

  • Tetracycline antibiotics
  • Fluoroquinolone antibiotics
  • Iron salts

⚡ Moderate Interactions

  • Digoxin
  • Ketoconazole

🍷 Alcohol Interaction

Alcohol can irritate the stomach lining and worsen the condition being treated. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to oxetacaine or aluminium hydroxide","Severe renal impairment","Hypophosphataemia"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment.","Avoid prolonged use without medical supervision.","May interfere with the absorption of other medicines; separate doses.","Not recommended for children unless prescribed by a doctor.","Consult a doctor if symptoms persist beyond 7 days."]

🤱 Lactation Safety

It is not known whether oxetacaine or aluminium hydroxide passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause constipation, abdominal pain, or in severe cases, aluminium toxicity. Treatment is symptomatic and supportive. Seek immediate medical attention if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the ingredients are evenly mixed. Measure the dose with the provided measuring cup or spoon; do not use a household spoon. It is best taken at bedtime or between meals, but follow your doctor's specific instructions. Do not exceed the recommended dose or duration without medical advice. Avoid taking other medicines within two hours of this product, as aluminium hydroxide can reduce the absorption of many drugs. If you have kidney disease, use this medicine only under strict medical supervision. Do not use it for longer than recommended without consulting your doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to constipation and aluminium accumulation. Use with caution, especially in those with reduced renal function. Monitor for signs of aluminium toxicity.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your surgeon. It may interact with other medications or affect healing. Follow your surgeon's instructions.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It is generally safe for dental procedures, but your dentist may need to know for medication interactions.

💚 Lifestyle Tips for Better Results

🏃
Avoid spicy, fatty, and acidic foods that can trigger heartburn.
🥗
Eat smaller, more frequent meals instead of large ones.
😴
Do not lie down immediately after eating; wait at least 2-3 hours.
💧
Elevate the head of your bed if you have night-time reflux.
🧘
Maintain a healthy weight to reduce pressure on the stomach.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Moderate exercise is generally safe. However, avoid vigorous exercise immediately after meals as it may worsen reflux. Listen to your body and stop if you feel discomfort.

🥗 Diet Recommendations

Include fibre-rich foods like fruits, vegetables, and whole grains.
Choose lean proteins such as chicken, fish, and tofu.
Avoid caffeine, chocolate, and mint, which can relax the lower oesophageal sphincter.
Stay well hydrated with water.
Limit carbonated drinks.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid these activities until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine, especially at high doses, may lead to aluminium accumulation, particularly in patients with kidney disease. This can cause bone pain, muscle weakness, and in severe cases, encephalopathy. Prolonged use may also cause hypophosphataemia. Regular monitoring of renal function and phosphate levels is advised if used for extended periods. It is not intended for long-term use without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Dietary changes, weight loss, and avoiding trigger foods can significantly reduce symptoms of acid reflux and gastritis.

Evidence: Well-established
Proton pump inhibitors

For more severe or persistent symptoms, doctors may prescribe PPIs to reduce acid production.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, if you are scheduled for any vaccine, inform your healthcare provider about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store at room temperature and protect from direct sunlight. If travelling across time zones, continue your regular dosing schedule as close as possible. Declare it at customs if required. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic gastritis
He was prescribed this medicine for persistent heartburn and stomach pain. After taking it as directed before meals, he noticed significant relief within a few days. He also reduced his intake of spicy foods and alcohol, which helped further.
💡 Lesson: Taking the medicine as prescribed and making lifestyle changes can greatly improve symptoms.
👤 A 60-year-old woman with diabetes and acid reflux
She needed an antacid but was concerned about sugar content. Her doctor prescribed this sugar-free suspension. She found it effective for her heartburn and did not experience any rise in blood sugar levels.
💡 Lesson: Sugar-free formulations are a good option for people with diabetes who need antacid therapy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The local anaesthetic effect starts within minutes, and the antacid effect also begins quickly. Symptomatic relief is usually felt within 30 minutes.

Q: Can I take it with other medicines?

A: It can interact with many medicines by reducing their absorption. Always separate this medicine from other oral drugs by at least 2 hours and consult your doctor.

Q: Is it safe for diabetics?

A: Yes, this is a sugar-free formulation, making it suitable for people with diabetes. However, always check with your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for jevacain suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure ulcers permanently.
    Fact: It provides symptomatic relief but does not eradicate the cause of ulcers. Proper treatment requires addressing the underlying cause.
  • Myth: It is safe to take indefinitely.
    Fact: Prolonged use can lead to aluminium accumulation and other side effects. Use only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Oxetacaine + Aluminium Hydroxide suspension

Brand Alternatives

  • Antarich Oral Suspension Sugar Free

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Oxetacaine + Aluminium Hydroxide","key_feature":"Sugar-free, local anaesthetic + antacid"},{"medicine":"Aluminium hydroxide + Magnesium hydroxide","composition":"Aluminium hydroxide + Magnesium hydroxide","key_feature":"Antacid only, no local anaesthetic"}]

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