Alfin 250mg Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice).
- Dark urine or pale stools.
- Severe pain in the upper right abdomen.
- A painful, spreading skin rash with blisters or peeling.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Unusual bruising or bleeding.
- Persistent nausea, vomiting, or loss of appetite.
- Severe headache with confusion or vision changes.
If experiencing severe symptoms, call emergency services immediately.
What is anibret 250mg tablet used for?
This medicine contains terbinafine 250 mg, an oral antifungal tablet used to treat fungal infections of the skin, hair, and nails. It works by blocking an enzyme that fungi need to build their cell membranes. The usual adult dose is 250 mg once daily, but the duration depends on the type of infection. It should be taken under medical supervision because it can rarely affect the liver.
- Generic Name: Terbinafine
- Manufacturer: Esma Formulations
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anibret 250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टर्बिनाफाइन 250 मिलीग्राम की एक ओरल एंटीफंगल टैबलेट है। इसका उपयोग त्वचा, बालों और नाखूनों के फंगल संक्रमण के इलाज के लिए किया जाता है, जैसे दाद, खाज-खुजली, एथलीट फुट और नाखून का फंगस। यह फंगस को मारने का काम करती है और संक्रमण को फैलने से रोकती है। यह दवा डॉक्टर की सलाह के बिना नहीं लेनी चाहिए क्योंकि यह कभी-कभी लिवर को प्रभावित कर सकती है।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे सिरदर्द, जी मिचलाना, पेट में गड़बड़ी, दस्त या हल्का रैश। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी स्वाद में बदलाव या भूख कम लगना भी हो सकता है। गंभीर दुष्प्रभाव बहुत कम होते हैं, लेकिन अगर आंखों या त्वचा का रंग पीला पड़े, गहरे रंग का पेशाब आए, पेट में तेज दर्द हो या शरीर पर छाले पड़ें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है। इस दवा को लेते समय शराब न पिएं क्योंकि इससे लिवर पर असर पड़ सकता है। अपने डॉक्टर को अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। दवा लेते समय लिवर की जांच करानी पड़ सकती है, इसलिए डॉक्टर के बताए सभी टेस्ट समय पर कराएं।
💊 anibret 250mg tablet Uses & Benefits
- [{"condition":"Onychomycosis (fungal nail infection)","description":"This medicine is used to treat fungal infections of the fingernails and toenails caused by dermatophytes.
- It helps clear the infection and allows healthy nail to grow.","evidence":"Well-established"},{"condition":"Tinea capitis (fungal scalp infection)","description":"This medicine is prescribed for scalp ringworm when oral treatment is needed, especially in cases where topical therapy is not enough.","evidence":"Well-established"},{"condition":"Tinea corporis (ringworm of the body)","description":"This medicine is used for extensive or stubborn ringworm infections of the body when oral therapy is considered appropriate.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"This medicine may be prescribed for persistent or widespread jock itch that has not responded to topical treatment.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"This medicine is used for severe or recurrent athlete's foot when oral antifungal therapy is needed.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cutaneous candidiasis","description":"This medicine is sometimes used off-label for certain skin yeast infections, but it is not the first-choice treatment.","evidence":"Limited"},{"condition":"Sporotrichosis","description":"This medicine has been used off-label in some cases of sporotrichosis, but evidence is limited and specialist guidance is required.","evidence":"Limited"}]
Primary treatment for: Fungal infections of the skin, hair, and nails (dermatophytosis).
Also treats: Onychomycosis, Tinea capitis, Tinea corporis, Tinea cruris, Tinea pedis
📋 Drug Information
| Generic Name(s) | Terbinafine |
| Brand Name | Af-ter Lotion |
| Manufacturer | Esma Formulations |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral. This medicine is taken by mouth as a tablet |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Keep it in the original container, tightly closed, and protect it from light and moisture. Do not store it in the bathroom. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture, but check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the fungal enzyme squalene epoxidase. This enzyme is needed to convert squalene into lanosterol, which is a building block for ergosterol in the fungal cell membrane. When the enzyme is blocked, squalene builds up inside the fungus and ergosterol production falls. The lack of ergosterol weakens the fungal cell membrane, and the excess squalene is toxic to the fungus. Together, these effects stop the fungus from growing and eventually kill it.
Mechanism Steps
💡 How to Take anibret 250mg tablet
Strength: Immediate-release tablet containing 250 mg of terbinafine.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg taken by mouth once daily. For skin infections, treatment may last 2 to 6 weeks. For fingernail infections, treatment may last 6 weeks, and for toenail infections, it may last 12 weeks. The exact dose and duration depend on the type and severity of the infection, your liver and kidney function, and other medicines you take. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially liver effects. The dose is usually the same as for younger adults, but your doctor may check your liver and kidney function more often. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In people with mild to moderate kidney problems, the usual dose may be used. In severe kidney disease, this medicine may need to be avoided or the dose reduced because it is removed more slowly from the body. Your doctor will decide the right dose based on your kidney function. |
| Hepatic Impairment | This medicine is not recommended for people with active liver disease or persistently abnormal liver tests. In people with mild liver impairment, it should be used with caution and liver function should be monitored. Your doctor will decide if the benefits outweigh the risks. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 250 mg once daily. Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anibret 250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Rifampin | Major | |
| Cimetidine | Major | |
| Warfarin | Moderate | |
| Amitriptyline | Moderate | |
| Metoprolol | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Rifampin
- Cimetidine
- Terbinafine (other products containing the same ingredient)
⚡ Moderate Interactions
- Tricyclic antidepressants (e.g., amitriptyline, nortriptyline)
- Beta-blockers (e.g., metoprolol)
- Oral contraceptives
- Warfarin and other oral anticoagulants
🍷 Alcohol Interaction
It is best to avoid alcohol while taking this medicine. Both alcohol and this medicine are metabolized by the liver, and drinking alcohol may increase the chance of liver-related side effects. If you do drink, keep it to a minimum and tell your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to terbinafine or any ingredient in this medicine.","Active liver disease or persistently abnormal liver function tests.","Severe kidney impairment without specialist supervision.","Breastfeeding, unless specifically approved by a doctor.","Pregnancy, unless the benefit clearly outweighs the risk."]
⚠️ Warnings & Precautions
["This medicine can rarely cause serious liver problems. Report yellowing of skin or eyes, dark urine, or severe tiredness immediately.","Avoid alcohol while taking this medicine to reduce the risk of liver injury.","Tell your doctor about all other medicines you take, especially antidepressants, beta-blockers, and blood thinners.","Do not use this medicine for fungal infections that can be treated with a topical cream unless your doctor advises oral therapy.","This medicine may reduce the effectiveness of oral contraceptives. Use a backup method of birth control.","If you develop a severe skin rash or blistering, stop the medicine and seek emergency care.","Do not share this medicine with others, even if they have similar symptoms."]
🤱 Lactation Safety
This medicine passes into breast milk. It is generally not recommended while breastfeeding unless your doctor decides it is essential. If you must take it, your doctor may advise monitoring the baby for any side effects.
💊 Overdose Management
If you take more than the prescribed dose of this medicine, contact your doctor or a poison control center right away. Symptoms of overdose may include nausea, vomiting, stomach pain, dizziness, and headache. Treatment is supportive and may include activated charcoal if the overdose is recent. Do not try to make yourself vomit unless a healthcare professional tells you to.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily with or without food. Do not crush, chew, or split the tablet unless your doctor advises otherwise. Avoid alcohol while taking this medicine because both are processed by the liver and alcohol may increase the risk of liver problems. Tell your doctor about all other medicines, supplements, and herbal products you use, especially antidepressants, beta-blockers, cimetidine, rifampin, and oral contraceptives. Do not start or stop this medicine on your own. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this medicine. Keep all follow-up appointments and blood tests as advised.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more prone to liver side effects and drug interactions because they often take multiple medicines. Your doctor may check your liver and kidney function more frequently. The dose is usually the same as for younger adults, but careful monitoring is important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor before starting or continuing it. This medicine may not be recommended during pregnancy unless clearly needed. Use effective contraception while taking this medicine and for a short period after stopping, as advised by your doctor.
🏥 Post-Surgery Considerations
This medicine does not usually interfere with surgery, but you should inform your surgeon and anesthesiologist that you are taking it. If you are scheduled for surgery, your doctor may advise you to continue or temporarily stop the medicine based on your overall health and liver function.
🦷 Dental Procedures
This medicine does not typically affect dental procedures. However, tell your dentist about all medicines you take, including this one, especially if you are taking blood thinners or have liver problems. Good oral hygiene is important, and fungal infections of the mouth are not treated with this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine does not usually limit exercise. However, if you feel dizzy or unwell, avoid strenuous activity until you feel better. If you have a fungal infection on your feet, keep them dry and wear clean socks during exercise. Avoid sharing gym equipment without cleaning it first.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness, headache, or stomach upset, avoid driving or operating heavy machinery until you feel better. You can continue your normal daily activities, but take care not to spread the fungal infection to others by sharing personal items.
🛑 When to Stop This Medicine
Do not stop this medicine before completing the prescribed course, even if you feel better, because the infection may return. However, stop immediately and seek medical help if you develop signs of a serious reaction such as yellowing of the skin or eyes, dark urine, severe skin rash, or difficulty breathing. Always consult your doctor before stopping the medicine for any other reason.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not needed for most skin infections, but nail infections may require up to 12 weeks of treatment. Prolonged use can increase the risk of liver injury and blood disorders. Your doctor may monitor your liver function periodically. If you need treatment for more than a few months, your doctor will reassess the risks and benefits. Do not continue this medicine beyond the prescribed duration without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild, localized fungal skin infections, creams containing clotrimazole, miconazole, or terbinafine may be enough.
Evidence: Well-establishedKeeping feet dry, wearing breathable footwear, and using antifungal powder can help prevent and manage athlete's foot.
Evidence: Well-establishedSome people use tea tree oil for mild fungal infections, but evidence is limited and it should not replace prescribed treatment.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and vaccines. You can receive routine vaccinations while taking this medicine. However, if you are unwell with a fever or severe infection, your doctor may advise delaying vaccination until you recover.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless the label says so.
✅ DO
Keep the tablets in the original container, tightly closed.
❌ DON'T
Do not transfer them to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about importing medicines. Keep the tablets in your hand luggage rather than checked baggage to avoid loss or extreme temperatures. Store them at room temperature and away from direct sunlight. If you are crossing time zones, continue taking your dose at the same interval as prescribed; you do not need to adjust the timing unless your doctor advises otherwise. Carry enough medicine for your entire trip plus a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice improvement in skin infections within 1 to 2 weeks. Nail infections take longer, often 6 to 12 weeks, because nails grow slowly.
A: Yes, you can take it with or without food. If it upsets your stomach, try taking it with a light meal.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double the dose.
A: This medicine can rarely cause liver problems. Your doctor may check your liver function before and during treatment. Report any yellowing of skin or eyes, dark urine, or severe tiredness immediately.
A: It is best to avoid alcohol because both alcohol and this medicine are processed by the liver, and together they may increase the risk of liver side effects.
A: This medicine may reduce the effectiveness of oral contraceptives. Use an additional non-hormonal method of contraception while taking it.
🤔 Common Patient Concerns
🔄 Substitutes for anibret 250mg tablet
View AllAlternative brands with exact same active ingredient:
-
hifen 250mg tabletLyka Labs ₹7.41 96.1% CHEAPER
-
Terfexx 250mg TabletVelite Pharmaceuticals ₹17.81 90.6% CHEAPER
-
tefdin 250mg tabletPsycormedies ₹23.11 87.8% CHEAPER
-
herpside 250mg tabletSurya Pharmaceutical Ltd ₹23.44 87.7% CHEAPER
-
terbofin 250mg tabletOchoa Laboratories Ltd ₹24.38 87.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any skin problem.
Fact: This medicine only treats fungal infections. It does not work for eczema, psoriasis, bacterial infections, or viral rashes. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor. Stopping early can allow the fungus to return and may lead to resistance. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for people with active liver disease or severe kidney disease, and it should be used with caution in pregnancy and breastfeeding. - Myth: This medicine works immediately.
Fact: It may take 1 to 2 weeks to see improvement in skin infections and several weeks to months for nail infections.
🔄 Alternative Options
Generic Alternatives
- Terbinafine 250 mg tablet
Brand Alternatives
- Alfin 250mg Tablet