J Flex 100mg Capsule - Celecoxib (100mg) medicine

Celebrex 100mg Capsule: Complete Medicine Guide

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🏭 Veritaz Healthcare Ltd 📦 strip of 10 capsules 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Chest pain, shortness of breath, or pain radiating to the arm or jaw
  • Sudden weakness, numbness, confusion, or difficulty speaking
  • Black or bloody stools, or vomiting blood
  • Severe abdominal pain or persistent indigestion
  • Swelling of the face, lips, tongue, or throat, or difficulty breathing
  • Decreased urination or swelling in the legs
  • Yellowing of the skin or eyes, or dark urine
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is J Flex 100mg Capsule used for?

This medicine is a selective COX-2 inhibitor NSAID used to treat pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by blocking the COX-2 enzyme, reducing prostaglandins that cause pain and swelling. It is taken orally, usually 100 mg twice daily or 200 mg once daily, with food. It carries risks of heart and stomach problems, so it should be used at the lowest effective dose for the shortest duration.

  • Generic Name: Celecoxib (100mg)
  • Manufacturer: Veritaz Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 J Flex 100mg Capsule के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), रीढ़ की अकड़न (एंकिलोज़िंग स्पॉन्डिलाइटिस), और तीव्र दर्द के इलाज के लिए इस्तेमाल की जाती है। यह सूजन और दर्द को कम करने में मदद करती है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, अपच, दस्त, मतली, पेट दर्द और हल्का चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें दिल का दौरा, स्ट्रोक, पेट में रक्तस्राव, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको सीने में दर्द, सांस लेने में कठिनाई, काला या खूनी मल, खून की उल्टी, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप से खुराक न बढ़ाएं। इसे भोजन के साथ या पानी के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर की सलाह के बिना यह दवा न लें। इस दवा को कमरे के तापमान पर सूखी जगह पर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 J Flex 100mg Capsule Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain, inflammation, and stiffness in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, swelling, and tenderness in adults with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and stiffness in the spine and other joints associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute pain","description":"Used for short-term management of acute pain, such as musculoskeletal pain or post-operative pain.","evidence":"Well-established"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain in women.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Familial adenomatous polyposis","description":"Sometimes prescribed off-label to reduce the number of colorectal polyps in patients with familial adenomatous polyposis.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally used off-label to prevent migraines, but evidence is limited and it is not a first-line option.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute pain, Primary dysmenorrhea

📋 Drug Information

Generic Name(s)Celecoxib (100mg)
Brand NameJ Flex 100mg Capsule
ManufacturerVeritaz Healthcare Ltd
Packaging / Formstrip of 10 capsules (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Keep the capsule in its original container until ready to use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce the risk of stomach upset.
2
Use the lowest effective dose for the shortest duration possible to minimize cardiovascular and gastrointestinal risks.
3
Monitor your blood pressure regularly while taking this medicine, as it can cause hypertension.
4
Inform your doctor if you have a history of heart disease, kidney problems, or stomach ulcers before starting this medicine.
5
Avoid taking other NSAIDs or blood thinners concurrently unless specifically advised by your doctor.
6
Report any signs of gastrointestinal bleeding, such as black stools or vomiting blood, immediately.
7
If you are scheduled for surgery, including dental procedures, inform your surgeon or dentist that you are taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
✅
Joint swelling and stiffness
This medicine helps reduce inflammation.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not typically used for headache unless prescribed for another condition.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is not well established but is thought to be high. Food, especially a high-fat meal, can delay absorption and increase peak plasma levels.
DistributionThis medicine is widely distributed throughout the body. It is highly protein-bound, primarily to albumin. The volume of distribution is approximately 400 L in healthy adults.
Protein BindingApproximately 97% bound to plasma proteins, mainly albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 2C9 (CYP2C9). The main metabolites are carboxylic acid derivatives, which are inactive.
Half-LifeThe elimination half-life is approximately 11 hours.
ExcretionThis medicine is excreted mainly in the feces (approximately 57%) and urine (approximately 27%) as metabolites. Less than 1% is excreted unchanged in urine.
BioavailabilityThe absolute bioavailability is not well established but is thought to be high, approximately 40-50% due to first-pass metabolism.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached in about 2 to 4 hours after oral administration.
Duration of ActionThe duration of pain relief is approximately 8 to 12 hours, but it may vary depending on the individual and the condition being treated.

How It Works

This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is induced during inflammation and pain. By blocking COX-2, it reduces the production of prostaglandins, which are chemicals that cause pain, swelling, and fever. Unlike non-selective NSAIDs, it has less effect on COX-1, an enzyme that protects the stomach lining and helps with blood clotting. This selectivity is thought to lower the risk of gastrointestinal ulcers, but it does not eliminate them completely. The exact mechanism for its analgesic and anti-inflammatory effects is not fully understood but is believed to involve both peripheral and central actions.

Mechanism Steps

1
Selective COX-2 binding: This medicine selectively binds to and inhibits the COX-2 enzyme, which is primarily induced during inflammation.
2
Reduced prostaglandin synthesis: By inhibiting COX-2, it decreases the production of prostaglandins, which are mediators of pain, inflammation, and fever.
3
Less COX-1 inhibition: Unlike non-selective NSAIDs, it has minimal effect on COX-1, which helps maintain stomach lining integrity and platelet function.
4
Analgesic and anti-inflammatory effects: The reduction in prostaglandins leads to decreased pain and swelling in inflamed tissues.
5
Antipyretic effect: It also reduces fever by acting on the hypothalamus to lower body temperature.

💡 How to Take J Flex 100mg Capsule

Strength: 100 mg immediate-release capsule

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3Take with food or milk to reduce stomach upset.
4Do not crush, chew, or open the capsule.
5Take at the same time each day to maintain consistent levels.
6If you miss a dose, follow the missed dose instructions.
7Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose for osteoarthritis is 200 mg once daily or 100 mg twice daily. For rheumatoid arthritis, the usual dose is 100 mg to 200 mg twice daily. For ankylosing spondylitis, the dose is 200 mg once daily or 100 mg twice daily. For acute pain, the initial dose is 400 mg, followed by 200 mg if needed on the first day, then 200 mg twice daily as needed. The maximum daily dose is 400 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be at increased risk of serious cardiovascular and gastrointestinal side effects. Use the lowest effective dose for the shortest duration. No specific dose adjustment is required based on age alone, but individualization is recommended.
Renal ImpairmentFor patients with mild to moderate kidney impairment (creatinine clearance 30-60 mL/min), no dose adjustment is necessary. For severe kidney impairment (creatinine clearance <30 mL/min), use is not recommended. Consult your doctor for individualized dosing.
Hepatic ImpairmentFor patients with mild liver impairment (Child-Pugh Class A), no dose adjustment is necessary. For moderate liver impairment (Child-Pugh Class B), reduce the dose by 50%. For severe liver impairment (Child-Pugh Class C), use is not recommended. Consult your doctor for individualized dosing.
Maximum Daily Dose400 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of J Flex 100mg Capsule

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Indigestion (Common (5-10%))
Take with food. If it continues, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if it lasts more than a few days.
Nausea (Common (5-10%))
Take with food. If it persists, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. If severe, contact your doctor.

🚨 Serious Side Effects

Heart attack (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or pain radiating to the arm or jaw.
Stroke (Rare (<0.1%))
Seek immediate medical attention if you experience sudden weakness, numbness, confusion, or difficulty speaking.
Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Kidney problems (Rare (<0.1%))
Contact your doctor if you notice decreased urination, swelling in legs, or fatigue.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, tongue, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Liver failure
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Severe skin reactions
Seek immediate medical attention if you develop a rash, blisters, or peeling skin.
Aseptic meningitis
Seek medical help if you experience severe headache, stiff neck, fever, or sensitivity to light.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
ACE inhibitors Major
Diuretics Major
Lithium Major
Fluconazole Major
Corticosteroids Moderate
Methotrexate Moderate
SSRIs Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • ACE inhibitors
  • Diuretics
  • Lithium
  • Fluconazole

⚡ Moderate Interactions

  • Corticosteroids
  • Methotrexate
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen stomach irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to celecoxib or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Use in the peri-operative period of coronary artery bypass graft (CABG) surgery","Severe heart failure","Active gastrointestinal bleeding or peptic ulcer","Severe kidney disease (e.g., creatinine clearance

⚠️ Warnings & Precautions

["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with cardiovascular risk factors.","Gastrointestinal bleeding, ulceration, and perforation can occur at any time without warning. Use with caution in patients with a history of peptic ulcer disease.","This medicine can cause kidney injury. Monitor kidney function in patients with kidney disease, heart failure, or dehydration.","Serious skin reactions have been reported. Discontinue at the first sign of rash or other allergic reaction.","This medicine may cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","Do not use this medicine for pain before or after CABG surgery.","Elderly patients are at higher risk of serious side effects. Use the lowest effective dose for the shortest duration."]

🤱 Lactation Safety

This medicine is excreted in human milk in low amounts. It is not recommended for use while breastfeeding unless the potential benefit justifies the potential risk to the infant. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe stomach pain, vomiting, drowsiness, and difficulty breathing. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis is not likely to be effective due to high protein binding.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or a glass of water to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Inform your doctor about all other medicines you are taking, especially blood thinners, ACE inhibitors, diuretics, and other NSAIDs. Do not use this medicine if you are pregnant, especially after 30 weeks, or breastfeeding without medical advice. If you have a history of heart disease, kidney problems, or stomach ulcers, your doctor will monitor you closely. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients (above 65 years) are at higher risk of serious cardiovascular and gastrointestinal side effects from this medicine. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid use in frail elderly patients unless clearly necessary.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, discuss with your doctor before taking this medicine. It is not recommended during pregnancy, especially in the third trimester, as it may cause harm to the fetus. Your doctor may recommend alternative treatments.

🏥 Post-Surgery Considerations

This medicine is contraindicated for pain management in the peri-operative period of coronary artery bypass graft (CABG) surgery. For other surgeries, consult your surgeon before taking this medicine. It may increase the risk of bleeding and kidney problems after surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding during dental work. Your dentist may recommend stopping the medicine temporarily or taking precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking can help improve joint mobility.
😴
Practice good posture to reduce strain on joints.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

While taking this medicine, you may experience reduced pain and improved mobility, but avoid overexertion. Start with gentle exercises and gradually increase intensity. If you experience increased pain, swelling, or dizziness during exercise, stop and consult your doctor. Avoid high-impact activities that stress your joints.

🥗 Diet Recommendations

Include omega-3 rich foods such as salmon, flaxseeds, and walnuts.
Reduce intake of processed foods and red meat.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated by drinking plenty of water.
Limit salt intake to help manage blood pressure.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities, but take precautions if you feel unwell. Inform your employer if your work involves operating machinery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as chest pain, difficulty breathing, severe stomach pain, or signs of an allergic reaction, seek immediate medical attention. Your doctor may advise stopping the medicine if your condition improves or if you develop complications.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of serious cardiovascular events, gastrointestinal bleeding, kidney problems, and liver toxicity. Regular monitoring of blood pressure, kidney and liver function is recommended. Use the lowest effective dose for the shortest duration possible. Discuss with your doctor if you need to use this medicine for more than a few weeks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Weight management

Losing excess weight reduces stress on joints and can alleviate pain.

Evidence: Well-established
Acupuncture

May help reduce pain in some individuals with osteoarthritis.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine. It is generally safe to receive vaccines while on this medicine, but consult your healthcare provider.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check local customs regulations regarding prescription medicines before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with knee osteoarthritis
He was prescribed this medicine 100 mg twice daily for knee pain. He took it with breakfast and dinner as advised. After two weeks, he noticed significant improvement in his morning stiffness and could walk longer distances without pain. He also started a low-impact exercise routine. He experienced mild indigestion initially, which resolved after taking it with food consistently.
💡 Lesson: Taking this medicine with food improves tolerability and consistency with the prescribed dose leads to better pain relief.
👤 A 45-year-old woman with rheumatoid arthritis
She had been struggling with joint pain and swelling in her hands and wrists. Her doctor prescribed this medicine 100 mg twice daily. She was initially worried about side effects but her doctor monitored her kidney and liver function regularly. After a month, her joint swelling decreased, and she could perform daily activities more comfortably. She was advised to avoid alcohol and to report any unusual symptoms.
💡 Lesson: Regular monitoring and adherence to prescribed dose are key to safe and effective use of this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 to 60 minutes after taking a dose. However, full anti-inflammatory effects may take several days to weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, taking this medicine with food or milk can help reduce stomach upset. It is generally recommended to take it with meals.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe for my heart?

A: This medicine may increase the risk of heart attack and stroke, especially with long-term use. Discuss your cardiovascular risk with your doctor before starting this medicine.

Q: Can I take this medicine if I am pregnant?

A: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus. Consult your doctor if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for J Flex 100mg Capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe for the stomach.
    Fact: While it may have a lower risk of stomach ulcers than some other NSAIDs, it can still cause gastrointestinal bleeding and ulcers.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription-only medicine and should only be taken under medical supervision.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus.

🔄 Alternative Options

Generic Alternatives

  • Celecoxib 100 mg capsule

Brand Alternatives

  • Celebrex 100mg Capsule

📊 Comparison with Similar Medicines

[{"medicine":"Celecoxib","class":"Selective COX-2 inhibitor","common_use":"Osteoarthritis, rheumatoid arthritis","gi_risk":"Lower than non-selective NSAIDs","cardiac_risk":"Increased"},{"medicine":"Ibuprofen","class":"Non-selective NSAID","common_use":"Pain, inflammation","gi_risk":"Higher","cardiac_risk":"Increased"},{"medicine":"Naproxen","class":"Non-selective NSAID","common_use":"Pain, inflammation","gi_risk":"Higher","cardiac_risk":"Increased"}]

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