Celebrex 100mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain, shortness of breath, or pain radiating to the arm or jaw
- Sudden weakness, numbness, confusion, or difficulty speaking
- Black or bloody stools, or vomiting blood
- Severe abdominal pain or persistent indigestion
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Decreased urination or swelling in the legs
- Yellowing of the skin or eyes, or dark urine
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is Celcox 100mg Capsule used for?
This medicine is a selective COX-2 inhibitor NSAID used to treat pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by blocking the COX-2 enzyme, reducing prostaglandins that cause pain and swelling. It is taken orally, usually 100 mg twice daily or 200 mg once daily, with food. It carries risks of heart and stomach problems, so it should be used at the lowest effective dose for the shortest duration.
- Generic Name: Celecoxib (100mg)
- Manufacturer: Lupin Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Celcox 100mg Capsule के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), रीढ़ की अकड़न (एंकिलोज़िंग स्पॉन्डिलाइटिस), और तीव्र दर्द के इलाज के लिए इस्तेमाल की जाती है। यह सूजन और दर्द को कम करने में मदद करती है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, अपच, दस्त, मतली, पेट दर्द और हल्का चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें दिल का दौरा, स्ट्रोक, पेट में रक्तस्राव, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको सीने में दर्द, सांस लेने में कठिनाई, काला या खूनी मल, खून की उल्टी, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप से खुराक न बढ़ाएं। इसे भोजन के साथ या पानी के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर की सलाह के बिना यह दवा न लें। इस दवा को कमरे के तापमान पर सूखी जगह पर रखें।
💊 Celcox 100mg Capsule Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, inflammation, and stiffness in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, swelling, and tenderness in adults with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and stiffness in the spine and other joints associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute pain","description":"Used for short-term management of acute pain, such as musculoskeletal pain or post-operative pain.","evidence":"Well-established"},{"condition":"Primary dysmenorrhea","description":"Relieves menstrual cramps and associated pain in women.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Familial adenomatous polyposis","description":"Sometimes prescribed off-label to reduce the number of colorectal polyps in patients with familial adenomatous polyposis.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally used off-label to prevent migraines, but evidence is limited and it is not a first-line option.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute pain, Primary dysmenorrhea
📋 Drug Information
| Generic Name(s) | Celecoxib (100mg) |
| Brand Name | Celcox 100mg Capsule |
| Manufacturer | Lupin Ltd |
| Packaging / Form | strip of 10 capsules (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Keep the capsule in its original container until ready to use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is induced during inflammation and pain. By blocking COX-2, it reduces the production of prostaglandins, which are chemicals that cause pain, swelling, and fever. Unlike non-selective NSAIDs, it has less effect on COX-1, an enzyme that protects the stomach lining and helps with blood clotting. This selectivity is thought to lower the risk of gastrointestinal ulcers, but it does not eliminate them completely. The exact mechanism for its analgesic and anti-inflammatory effects is not fully understood but is believed to involve both peripheral and central actions.
Mechanism Steps
💡 How to Take Celcox 100mg Capsule
Strength: 100 mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose for osteoarthritis is 200 mg once daily or 100 mg twice daily. For rheumatoid arthritis, the usual dose is 100 mg to 200 mg twice daily. For ankylosing spondylitis, the dose is 200 mg once daily or 100 mg twice daily. For acute pain, the initial dose is 400 mg, followed by 200 mg if needed on the first day, then 200 mg twice daily as needed. The maximum daily dose is 400 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be at increased risk of serious cardiovascular and gastrointestinal side effects. Use the lowest effective dose for the shortest duration. No specific dose adjustment is required based on age alone, but individualization is recommended. |
| Renal Impairment | For patients with mild to moderate kidney impairment (creatinine clearance 30-60 mL/min), no dose adjustment is necessary. For severe kidney impairment (creatinine clearance <30 mL/min), use is not recommended. Consult your doctor for individualized dosing. |
| Hepatic Impairment | For patients with mild liver impairment (Child-Pugh Class A), no dose adjustment is necessary. For moderate liver impairment (Child-Pugh Class B), reduce the dose by 50%. For severe liver impairment (Child-Pugh Class C), use is not recommended. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | 400 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Celcox 100mg Capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Fluconazole | Major | |
| Corticosteroids | Moderate | |
| Methotrexate | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Warfarin
- ACE inhibitors
- Diuretics
- Lithium
- Fluconazole
⚡ Moderate Interactions
- Corticosteroids
- Methotrexate
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen stomach irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to celecoxib or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Use in the peri-operative period of coronary artery bypass graft (CABG) surgery","Severe heart failure","Active gastrointestinal bleeding or peptic ulcer","Severe kidney disease (e.g., creatinine clearance
⚠️ Warnings & Precautions
["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with cardiovascular risk factors.","Gastrointestinal bleeding, ulceration, and perforation can occur at any time without warning. Use with caution in patients with a history of peptic ulcer disease.","This medicine can cause kidney injury. Monitor kidney function in patients with kidney disease, heart failure, or dehydration.","Serious skin reactions have been reported. Discontinue at the first sign of rash or other allergic reaction.","This medicine may cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","Do not use this medicine for pain before or after CABG surgery.","Elderly patients are at higher risk of serious side effects. Use the lowest effective dose for the shortest duration."]
🤱 Lactation Safety
This medicine is excreted in human milk in low amounts. It is not recommended for use while breastfeeding unless the potential benefit justifies the potential risk to the infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe stomach pain, vomiting, drowsiness, and difficulty breathing. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis is not likely to be effective due to high protein binding.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or a glass of water to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Inform your doctor about all other medicines you are taking, especially blood thinners, ACE inhibitors, diuretics, and other NSAIDs. Do not use this medicine if you are pregnant, especially after 30 weeks, or breastfeeding without medical advice. If you have a history of heart disease, kidney problems, or stomach ulcers, your doctor will monitor you closely. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of serious cardiovascular and gastrointestinal side effects from this medicine. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid use in frail elderly patients unless clearly necessary.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. It is not recommended during pregnancy, especially in the third trimester, as it may cause harm to the fetus. Your doctor may recommend alternative treatments.
🏥 Post-Surgery Considerations
This medicine is contraindicated for pain management in the peri-operative period of coronary artery bypass graft (CABG) surgery. For other surgeries, consult your surgeon before taking this medicine. It may increase the risk of bleeding and kidney problems after surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding during dental work. Your dentist may recommend stopping the medicine temporarily or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience reduced pain and improved mobility, but avoid overexertion. Start with gentle exercises and gradually increase intensity. If you experience increased pain, swelling, or dizziness during exercise, stop and consult your doctor. Avoid high-impact activities that stress your joints.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities, but take precautions if you feel unwell. Inform your employer if your work involves operating machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as chest pain, difficulty breathing, severe stomach pain, or signs of an allergic reaction, seek immediate medical attention. Your doctor may advise stopping the medicine if your condition improves or if you develop complications.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of serious cardiovascular events, gastrointestinal bleeding, kidney problems, and liver toxicity. Regular monitoring of blood pressure, kidney and liver function is recommended. Use the lowest effective dose for the shortest duration possible. Discuss with your doctor if you need to use this medicine for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedLosing excess weight reduces stress on joints and can alleviate pain.
Evidence: Well-establishedMay help reduce pain in some individuals with osteoarthritis.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine. It is generally safe to receive vaccines while on this medicine, but consult your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check local customs regulations regarding prescription medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30 to 60 minutes after taking a dose. However, full anti-inflammatory effects may take several days to weeks of regular use.
A: Yes, taking this medicine with food or milk can help reduce stomach upset. It is generally recommended to take it with meals.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine may increase the risk of heart attack and stroke, especially with long-term use. Discuss your cardiovascular risk with your doctor before starting this medicine.
A: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for Celcox 100mg Capsule
View AllAlternative brands with exact same active ingredient:
-
Orthocel 100mg TabletBiochem Pharmaceutical Industries ₹25.31 1.9% COSTLIER
-
Celira 100mg CapsuleShreya Life Sciences Pvt Ltd ₹30.00 20.8% COSTLIER
-
Celib 100mg CapsuleTorrent Pharmaceuticals Ltd ₹34.31 38.1% COSTLIER
-
Colcibra 100mg TabletSun Pharmaceutical Industries Ltd ₹37.50 51% COSTLIER
-
Celact 100mg Tablet MDSun Pharmaceutical Industries Ltd ₹39.57 59.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is completely safe for the stomach.
Fact: While it may have a lower risk of stomach ulcers than some other NSAIDs, it can still cause gastrointestinal bleeding and ulcers. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription-only medicine and should only be taken under medical supervision. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus.
🔄 Alternative Options
Generic Alternatives
- Celecoxib 100 mg capsule
Brand Alternatives
- Celebrex 100mg Capsule