Metrogyl 200 Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing.
- A widespread rash with blisters or peeling skin.
- Severe abdominal pain that may spread to the back, with nausea and vomiting.
- Numbness, tingling, or weakness in the hands or feet.
- A seizure or unusual confusion.
- Yellowing of the eyes or skin, or dark urine.
- Unusual tiredness, fever, sore throat, or easy bruising.
- Severe headache with fever, neck stiffness, or sensitivity to light.
If experiencing severe symptoms, call emergency services immediately.
What is iveomezoled 200mg injection used for?
This medicine contains Metronidazole 200 mg, an antibiotic and antiparasitic tablet used to treat infections such as amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, and certain dental and anaerobic infections. It works by damaging the DNA of the infecting organisms. It is taken by mouth, usually with food, and alcohol must be strictly avoided during treatment and for 48 hours after.
- Generic Name: Metronidazole (200mg)
- Manufacturer: Fresenius Kabi India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 iveomezoled 200mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेट्रोनिडाजोल 200 मिलीग्राम की गोली है, जिसका उपयोग कई प्रकार के बैक्टीरिया और परजीवी संक्रमणों के इलाज के लिए किया जाता है। इसमें पेट और आंतों के संक्रमण जैसे अमीबियासिस और जियार्डियासिस, दांत और मसूड़ों के संक्रमण, बैक्टीरियल वेजिनोसिस, और कुछ एनारोबिक बैक्टीरिया के संक्रमण शामिल हैं। यह दवा संक्रमण पैदा करने वाले कीटाणुओं के डीएनए को नष्ट करके उन्हें मार देती है। इसे डॉक्टर के निर्देशानुसार खाने के साथ लेना चाहिए। इस दवा को लेते समय और आखिरी खुराक के 48 घंटे बाद तक शराब बिल्कुल नहीं पीनी चाहिए, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, मुँह में धातु जैसा स्वाद, सिरदर्द, पेट में असहजता और चक्कर आना शामिल हैं। ये आमतौर पर हल्के होते हैं और इलाज जारी रखने पर ठीक हो जाते हैं। कभी-कभी मुँह सूखना, जीभ पर परत जमना या स्वाद में बदलाव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें तेज एलर्जी, चेहरे या गले में सूजन, सांस लेने में कठिनाई, दौरे, हाथ-पैरों में झुनझुनी या कमजोरी, और अग्न्याशय की सूजन शामिल हो सकते हैं। अगर ऐसा कुछ हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न बदलें और इलाज बीच में न छोड़ें, भले ही आप बेहतर महसूस करें। गोली को पानी के साथ निगलें और खाने के साथ या तुरंत बाद लें ताकि पेट खराब न हो। इलाज के दौरान और आखिरी खुराक के 48 घंटे बाद तक शराब बिल्कुल न पिएं। अगर आपको लीवर या किडनी की बीमारी है, या कोई तंत्रिका तंत्र की समस्या है, तो डॉक्टर को बताएं। गर्भवती होने, गर्भधारण की योजना बनाने या स्तनपान कराने के बारे में डॉक्टर से सलाह लें। यह दवा दूसरों के साथ साझा न करें।
💊 iveomezoled 200mg injection Uses & Benefits
- [{"condition":"Amoebiasis (intestinal and hepatic)","description":"This medicine is used to treat infection caused by Entamoeba histolytica, including amoebic dysentery and amoebic liver abscess, often followed by a luminal agent to clear cysts.","evidence":"Well-established"},{"condition":"Giardiasis","description":"It is a first-line treatment for diarrhoea and malabsorption caused by Giardia lamblia.","evidence":"Well-established"},{"condition":"Trichomoniasis","description":"This medicine is highly effective against Trichomonas vaginalis infection and is usually given to sexual partners as well to prevent reinfection.","evidence":"Well-established"},{"condition":"Bacterial vaginosis","description":"It is commonly prescribed to treat the overgrowth of anaerobic bacteria in the vagina, relieving discharge and odour.","evidence":"Well-established"},{"condition":"Anaerobic bacterial infections","description":"It is used for infections caused by susceptible anaerobic bacteria, including intra-abdominal infections, pelvic infections, and aspiration pneumonia, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Dental and gum infections","description":"This medicine is used for acute necrotising ulcerative gingivitis and other anaerobic dental infections, sometimes with amoxicillin.","evidence":"Well-established"},{"condition":"Helicobacter pylori eradication","description":"It is a component of some multi-drug regimens used to eradicate H.
- pylori in peptic ulcer disease.","evidence":"Well-established"},{"condition":"Clostridioides difficile infection (mild to moderate)","description":"This medicine is an alternative to vancomycin for mild to moderate C.
- difficile infection when first-line options are not suitable.","evidence":"Established"}]
Off-label uses: [{"condition":"Rosacea","description":"Topical or oral Metronidazole is sometimes used for inflammatory rosacea, but this tablet form is not the usual first choice.","evidence":"Limited"},{"condition":"Crohn's disease with perianal involvement","description":"Occasionally used as part of combination therapy for perianal fistulising Crohn's disease.","evidence":"Limited"},{"condition":"Bacterial overgrowth in the small intestine","description":"Sometimes prescribed when other antibiotics are not effective, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Anaerobic bacterial and parasitic infections
Also treats: Amoebiasis, Giardiasis, Trichomoniasis, Bacterial vaginosis, Dental infections, Helicobacter pylori infection
📋 Drug Information
| Generic Name(s) | Metronidazole (200mg) |
| Brand Name | iveomezoled 200mg injection |
| Manufacturer | Fresenius Kabi India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | 5-Nitroimidazole (Antiprotozoal & Antibacterial) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Metronidazole is included in the WHO Model List of Essential Medicines for the treatment of anaerobic infections and protozoal infections. Specific regimens should follow current national and WHO guidelines. |
| ICMR Guideline | The Indian Council of Medical Research recognises Metronidazole as a first-line treatment for amoebiasis, giardiasis, and trichomoniasis. It is also included in standard treatment guidelines for anaerobic infections. Always follow the latest ICMR guidelines and your doctor's advice. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a nitroimidazole antimicrobial that works by entering susceptible bacteria and parasites and being reduced by their internal electron transport proteins. This reduction creates reactive compounds that damage the organism's DNA, breaking its strands and preventing it from copying itself. As a result, the microbe cannot multiply and is killed. Because this process depends on the low-oxygen environment inside certain bacteria and parasites, the medicine is selective for those organisms and has little effect on normal human cells.
Mechanism Steps
💡 How to Take iveomezoled 200mg injection
Strength: Metronidazole 200 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine depends on the infection being treated. For many infections, 200 mg to 400 mg is taken two or three times a day, but the exact dose, frequency, and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For some conditions, a higher dose or a single large dose may be used. Always follow your doctor's prescription exactly and complete the full course. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and nerve-related symptoms. Dose adjustment may be needed based on liver and kidney function. Your doctor will decide the appropriate dose. |
| Renal Impairment | In severe kidney disease, the dose may need to be reduced, and the dosing interval may be lengthened. Your doctor will determine the appropriate adjustment based on your kidney function. |
| Hepatic Impairment | In severe liver disease, the dose may need to be reduced because the medicine is metabolised by the liver. Your doctor will decide the appropriate dose and monitor you closely. |
| Maximum Daily Dose | The maximum daily dose depends on the infection and is determined by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of iveomezoled 200mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Lithium | Major | |
| Alcohol | Major | |
| Disulfiram | Major | |
| Phenytoin | Major | |
| Cimetidine | Moderate | |
| Carbamazepine | Moderate | |
| Cyclosporine | Moderate | |
| Tacrolimus | Moderate | |
| Fluorouracil | Moderate |
🚨 Major Interactions
- Alcohol (ethanol)
- Warfarin
- Lithium
- Disulfiram
- Phenytoin
⚡ Moderate Interactions
- Cimetidine
- Carbamazepine
- Cyclosporine
- Tacrolimus
- Fluorouracil
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 48 hours after the last dose. Combining them can cause a disulfiram-like reaction with severe nausea, vomiting, flushing, headache, and a fast heartbeat. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Metronidazole or other nitroimidazole medicines.","Use of disulfiram within the past two weeks.","First trimester of pregnancy, unless the doctor decides it is essential.","Alcohol consumption during treatment and for at least 48 hours after.","Severe liver disease, unless under close medical supervision."]
⚠️ Warnings & Precautions
["Avoid alcohol completely during treatment and for at least 48 hours after the last dose.","Tell your doctor if you have liver disease, kidney disease, or a nervous system disorder.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Prolonged use may cause numbness or tingling in the hands or feet; report these symptoms to your doctor.","This medicine may interfere with certain blood tests; inform the laboratory staff that you are taking it.","Do not share this medicine with others.","If you are pregnant or breastfeeding, consult your doctor before taking this medicine."]
🤱 Lactation Safety
Metronidazole passes into breast milk. For a single dose, breastfeeding may be paused for 12 to 24 hours after the dose. For longer courses, your doctor may advise either interrupting breastfeeding during treatment and for 12 to 24 hours after the last dose, or using a shorter course. Discuss with your doctor to decide what is best for you and your baby.
💊 Overdose Management
If you take too much of this medicine, seek immediate medical attention. Overdose may cause nausea, vomiting, dizziness, headache, and in severe cases, numbness, seizures, or confusion. Treatment is supportive and may include activated charcoal if taken recently. Do not try to vomit unless told to do so by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop treatment early, even if you feel better, because the infection may return. Swallow the tablet whole with a full glass of water and take it with or just after food to reduce stomach upset. Avoid all alcohol, including beer, wine, and alcohol-containing medicines or mouthwashes, during treatment and for at least 48 hours after the last dose. Alcohol can cause a distressing reaction with severe nausea, vomiting, flushing, headache, and a fast heartbeat. Tell your doctor if you have liver disease, kidney disease, or a nervous system disorder before starting this medicine. Inform your doctor about all other medicines you take, especially blood thinners such as warfarin, lithium, and medicines for seizures. If you are pregnant, planning pregnancy, or breastfeeding, discuss this with your doctor before taking this medicine. Do not share this medicine with anyone else, even if they have similar symptoms. Keep this medicine out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to side effects such as dizziness, confusion, and peripheral neuropathy. Dose adjustment may be needed based on liver and kidney function. Your doctor will monitor you closely and may recommend a lower dose.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive, discuss this with your doctor before taking this medicine. It is generally avoided in the first trimester. Your doctor may recommend delaying treatment or using an alternative if appropriate. Use effective contraception during treatment if you are of childbearing age.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to prevent or treat anaerobic infections. Follow your surgeon's instructions carefully. Inform your surgical team if you are taking this medicine before any operation.
🦷 Dental Procedures
This medicine is sometimes prescribed for dental infections. Inform your dentist if you are taking it before any dental procedure. It may interact with other medicines used during dental work, so always disclose your full medication list.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue in some people. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you feel unsteady, rest and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or nausea in some people. If you experience these, avoid driving or operating heavy machinery until you feel better. Most people can continue their usual activities, but take precautions if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the prescribed course, even if you feel better, as the infection may return. If you experience serious side effects such as severe allergic reaction, seizures, or numbness in the hands or feet, stop the medicine and seek medical help immediately. Always consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of peripheral neuropathy, which causes numbness, tingling, or weakness in the hands and feet. It may also rarely affect the blood or liver. Prolonged use can lead to fungal infections such as oral thrush. Regular monitoring may be needed if you take it for a long time. Always follow your doctor's advice and do not use it for longer than prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A related antibiotic that may be used as an alternative for some infections, often with a shorter course.
Evidence: Well-establishedAnother nitroimidazole that can be used for similar infections.
Evidence: Well-establishedFor mild infections, rest, hydration, and a bland diet may help while the body fights the infection, but antibiotics are usually needed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are unwell with an infection, your doctor may advise delaying vaccination until you recover. Follow your doctor's advice regarding routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking your doses at the same intervals as prescribed; you may need to adjust the timing gradually. Check the customs regulations of your destination regarding prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 1 to 2 days, but it is important to complete the full course as prescribed.
A: No, you must avoid alcohol completely during treatment and for at least 48 hours after the last dose to prevent a serious reaction.
A: Take it as soon as you remember if it is not almost time for your next dose. If it is, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is generally avoided in the first trimester unless clearly needed. Consult your doctor before taking it during pregnancy.
A: It may be prescribed for dental infections, but you should not self-medicate. Consult a dentist or doctor for proper diagnosis and treatment.
🤔 Common Patient Concerns
🔄 Substitutes for iveomezoled 200mg injection
View AllAlternative brands with exact same active ingredient:
-
Tosgyl 200mg TabletTOSC International Pvt Ltd ₹3.00 86.9% CHEAPER
-
aristogyl 200mg tabletAristo Pharmaceuticals Pvt Ltd ₹3.98 82.6% CHEAPER
-
metron 200mg tabletAlkem Laboratories Ltd ₹4.27 81.3% CHEAPER
-
unimegyl 200mg tabletTorrent Pharmaceuticals Ltd ₹4.69 79.5% CHEAPER
-
metropro 200mg tabletAvecia Healthcare ₹7.00 69.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Metrogyl 200 is a painkiller.
Fact: This medicine is an antibiotic and antiparasitic, not a painkiller. It treats the infection that may be causing pain. - Myth: You can stop taking it once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce the risk of resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a serious reaction with severe nausea, vomiting, and flushing. Avoid it completely during treatment and for 48 hours after. - Myth: Metrogyl 200 can be used for any diarrhoea.
Fact: It is only effective for specific bacterial and parasitic infections. Using it for other causes of diarrhoea is not helpful and may cause side effects.
🔄 Alternative Options
Generic Alternatives
- Metronidazole 200 mg tablet
Brand Alternatives
- Metrogyl 200 tablet