it pride 100mg capsule - Itraconazole (100mg) medicine

It-mac 100 Capsule: Complete Guide to Uses, Side Effects, and Safety

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🏭 Care Pride Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes, dark urine, or severe fatigue
  • Swelling of legs, ankles, or abdomen, or sudden weight gain
  • Shortness of breath or difficulty breathing
  • Severe skin rash with blisters or peeling
  • Numbness, tingling, or burning in hands or feet
  • Fever, sore throat, or unusual bleeding or bruising
  • Chest pain or irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is it pride 100mg capsule used for?

This medicine is an oral antifungal containing itraconazole 100 mg. It is used to treat fungal infections of the skin, nails, mouth, and internal organs. It works by damaging the fungal cell membrane. Take it with food for best absorption. Do not use if you have heart failure or are taking certain interacting medicines.

  • Generic Name: Itraconazole (100mg)
  • Manufacturer: Care Pride Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 it pride 100mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा इट्राकोनाज़ोल 100 मिलीग्राम कैप्सूल है, जिसका उपयोग फंगल संक्रमण के इलाज के लिए किया जाता है। यह त्वचा, नाखून, मुंह और शरीर के आंतरिक अंगों के फंगल संक्रमण में प्रभावी है। यह फंगस की कोशिका झिल्ली को नष्ट करके उसके विकास को रोकती है। इसे भोजन के साथ लेना चाहिए ताकि यह अच्छी तरह से अवशोषित हो सके। हृदय विफलता या गंभीर यकृत रोग वाले मरीजों को यह दवा नहीं लेनी चाहिए। इस दवा को डॉक्टर के परामर्श के बिना न लें और न ही बीच में बंद करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द और त्वचा पर चकत्ते शामिल हैं। ये आमतौर पर हल्के होते हैं और इलाज जारी रखने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें यकृत की क्षति, हृदय विफलता, गंभीर एलर्जी और तंत्रिका संबंधी समस्याएं शामिल हो सकती हैं। अगर आपको आंखों या त्वचा का पीलापन, गहरे रंग का पेशाब, सांस लेने में कठिनाई, पैरों में सूजन, या हाथ-पैरों में झुनझुनी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे दूसरों के साथ साझा न करें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, क्योंकि यह कई दवाओं के साथ प्रतिक्रिया कर सकती है। इलाज के दौरान शराब न पिएं। अगर आप गर्भवती हो सकती हैं, तो इलाज के दौरान और आखिरी खुराक के बाद कम से कम दो महीने तक गर्भनिरोधक का इस्तेमाल करें। लक्षण ठीक होने पर भी दवा बीच में न छोड़ें, वरना संक्रमण फिर से हो सकता है। नियमित जांच और फॉलो-अप के लिए डॉक्टर के पास जाएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 it pride 100mg capsule Uses & Benefits

  • [{"condition":"Dermatophytosis (skin, hair, and nail infections)","description":"This medicine is used to treat fungal infections of the skin, hair, and nails caused by dermatophytes.
  • It helps clear the infection and relieve symptoms such as itching, scaling, and redness.","evidence":"Well-established"},{"condition":"Onychomycosis (fungal nail infection)","description":"This medicine is prescribed for fungal infections of the toenails and fingernails.
  • It is often given in pulse dosing regimens to achieve high drug levels in the nail tissue.","evidence":"Well-established"},{"condition":"Oral and esophageal candidiasis","description":"This medicine is used to treat yeast infections of the mouth and esophagus, especially in patients with weakened immune systems.
  • It helps relieve pain and difficulty swallowing.","evidence":"Well-established"},{"condition":"Systemic fungal infections","description":"This medicine is used for systemic infections such as histoplasmosis, blastomycosis, and aspergillosis in appropriate patients.
  • It may be used as initial therapy or after other treatments.","evidence":"Well-established"},{"condition":"Allergic bronchopulmonary aspergillosis (ABPA)","description":"This medicine may be used in certain patients with ABPA to reduce fungal burden and control symptoms.
  • It is usually part of a broader treatment plan.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Tinea versicolor","description":"Sometimes prescribed off-label for widespread or recurrent tinea versicolor when topical treatments are not effective.","evidence":"Limited"},{"condition":"Seborrheic dermatitis","description":"Occasionally used off-label for severe seborrheic dermatitis, though topical antifungals are usually preferred.","evidence":"Limited"}]

Primary treatment for: Fungal infections

Also treats: Dermatophytosis, Onychomycosis, Candidiasis, Histoplasmosis, Aspergillosis

📋 Drug Information

Generic Name(s)Itraconazole (100mg)
Brand Nameit pride 100mg capsule
ManufacturerCare Pride Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with a full meal to ensure proper absorption.
2
Do not take antacids or acid-reducing medicines within 2 hours of this medicine.
3
Inform your doctor immediately if you have heart failure or any heart condition.
4
Avoid grapefruit juice and alcohol while on this medicine.
5
Complete the full course even if symptoms improve to prevent recurrence.
6
Report any signs of liver problems like yellowing of eyes or dark urine.
7
Use effective contraception during treatment and for two months after.
8
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Itchy, scaly skin rash
This medicine is commonly prescribed for skin fungal infections.
Likely Use
Thick, discolored nails
This medicine is used for nail fungal infections.
Likely Use
White patches in mouth or throat
This medicine is used for oral candidiasis.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract, but absorption is variable and depends on gastric acidity and food intake. Taking it with a full meal significantly increases absorption. Acid-reducing medicines can reduce absorption.
DistributionThis medicine is highly lipophilic and distributes widely into tissues, including skin, nails, and fatty tissue. It accumulates in keratinous tissues, which is why it remains effective in nails for months after treatment ends.
Protein BindingThis medicine is approximately 99.8% bound to plasma proteins, primarily albumin.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4. It produces multiple metabolites, some of which have antifungal activity.
Half-LifeThe elimination half-life of this medicine is approximately 21 hours after a single dose, but it increases to about 30-40 hours with repeated dosing due to tissue accumulation.
ExcretionThis medicine is excreted mainly in the urine and feces as inactive metabolites. About 35% of a dose is excreted in urine and 54% in feces over 4 days.
BioavailabilityThe bioavailability of this medicine is variable, ranging from 40% to 55% when taken with food. It is higher when taken with a full meal compared to fasting.
Onset of ActionThe onset of action depends on the infection being treated. Improvement in skin infections may be seen within 1-2 weeks, while nail infections may take several months to clear.
Peak Plasma TimePeak plasma concentration is reached approximately 2 to 5 hours after oral administration.
Duration of ActionThe duration of action varies with the infection and treatment duration. For skin infections, effects last as long as treatment continues. For nail infections, the drug remains in the nail for several months after stopping treatment.

How It Works

This medicine works by inhibiting the fungal enzyme cytochrome P450 14-alpha-demethylase, which is responsible for converting lanosterol to ergosterol. Ergosterol is a vital component of the fungal cell membrane. When ergosterol production is blocked, the fungal cell membrane becomes weak and leaky, leading to cell death and inhibition of fungal growth. This medicine is active against a broad range of fungi, including dermatophytes, yeasts, and dimorphic fungi.

Mechanism Steps

1
Binding to fungal CYP51: This medicine binds to the heme iron of fungal cytochrome P450 14-alpha-demethylase, blocking its activity.
2
Inhibition of ergosterol synthesis: Without this enzyme, the fungus cannot convert lanosterol to ergosterol, a key component of its cell membrane.
3
Membrane disruption: The lack of ergosterol weakens the fungal cell membrane, making it leaky and unable to function properly.
4
Fungal growth inhibition and death: The damaged membrane leads to inhibition of fungal growth and, in some cases, cell death. The body's immune system can then clear the infection.

💡 How to Take it pride 100mg capsule

Strength: Itraconazole 100 mg immediate-release capsule

1Take this medicine with a full meal to improve absorption.
2Swallow the capsule whole with a glass of water.
3Do not crush, chew, or open the capsule.
4Take it at the same time each day to maintain consistent levels.
5If you are on acid-reducing medicines, take this medicine with an acidic beverage like cola, or consult your doctor.
6Do not take antacids within 2 hours of this medicine.

Dosage Information

Adult DosageThe dose of this medicine depends on the type and severity of the fungal infection. For skin infections, a typical dose is 100 mg to 200 mg once daily for 7 to 15 days. For nail infections, pulse dosing of 200 mg twice daily for one week per month for 2 to 3 months may be used. For systemic infections, doses may be higher and duration longer. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be needed based on liver and kidney function. Consult your doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be needed in patients with severe kidney impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentThis medicine is extensively metabolized in the liver. Dose reduction may be needed in patients with liver cirrhosis or severe liver impairment. Monitor liver function closely.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg per day, but this depends on the indication and must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Full meal
Take with a full meal
Increases absorption of itraconazole.
Grapefruit juice
Avoid
May increase drug levels and side effects.
Acidic beverages (e.g., cola)
May enhance absorption
Increased stomach acidity can improve absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of it pride 100mg capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. Avoid fatty or spicy foods. Consult doctor if severe or persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Use acetaminophen if needed, but consult your doctor first.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, contact your doctor.
Rash (Common (1-5%))
Monitor for worsening. If rash spreads or is accompanied by fever, seek medical attention.

🚨 Serious Side Effects

Liver injury (hepatotoxicity) (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, severe fatigue, or right upper abdominal pain.
Heart failure (Rare (<0.1%))
Seek immediate care if you experience swelling of legs or abdomen, shortness of breath, or sudden weight gain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face, lips, or throat, or a severe rash.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning in hands or feet to your doctor promptly.
Hearing loss (Rare (<0.1%))
Inform your doctor if you notice any hearing changes or ringing in the ears.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek emergency care if you develop painful skin rash, blisters, or peeling skin.
Toxic epidermal necrolysis
Seek emergency care immediately if you have severe skin peeling or blistering.
Agranulocytosis
Report fever, sore throat, or unusual infections to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Simvastatin Major
Midazolam Major
Rifampicin Major
Clarithromycin Moderate
Omeprazole Moderate
Nifedipine Moderate
Glibenclamide Moderate
Antacids Minor
Sucralfate Minor

🚨 Major Interactions

  • Cisapride, quinidine, pimozide, levomethadyl
  • Midazolam, triazolam
  • Statins (simvastatin, lovastatin)
  • Warfarin
  • Rifampicin, rifabutin, phenytoin, carbamazepine

⚡ Moderate Interactions

  • Calcium channel blockers (e.g., nifedipine, amlodipine)
  • Oral hypoglycemics (e.g., glibenclamide)
  • Proton pump inhibitors (e.g., omeprazole)
  • H2 blockers (e.g., ranitidine)
  • Macrolide antibiotics (e.g., clarithromycin)

🍷 Alcohol Interaction

Alcohol may increase the risk of liver damage and stomach upset when taken with this medicine. It is advisable to avoid alcohol during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to itraconazole or other azole antifungals","Ventricular dysfunction or heart failure","Concurrent use with cisapride, quinidine, pimozide, levomethadyl","Concurrent use with midazolam or triazolam","Concurrent use with certain statins (simvastatin, lovastatin)","Pregnancy for onychomycosis (except in life-threatening cases)"]

⚠️ Warnings & Precautions

["This medicine should be taken with food to ensure adequate absorption.","Avoid use in patients with heart failure or ventricular dysfunction.","Monitor liver function before and during treatment.","Use with caution in patients with kidney disease.","Avoid alcohol during treatment.","Use effective contraception during treatment and for two months after.","Do not use for onychomycosis in pregnant women.","Report any signs of liver problems, heart failure, or neuropathy immediately.","Inform your doctor of all other medicines you are taking."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is not recommended during breastfeeding unless the benefit outweighs the risk. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

There is no specific antidote for overdose with this medicine. Treatment should be symptomatic and supportive. If overdose is suspected, contact a poison control center or emergency room immediately. Gastric lavage may be considered if ingestion is recent.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others, even if they have similar symptoms. Inform your doctor about all other medicines you are taking, including over-the-counter products and herbal supplements, because this medicine can interact with many drugs. Avoid alcohol while taking this medicine. Use effective contraception during treatment and for at least two months after the last dose if you are a woman of childbearing potential. Do not stop treatment early, even if you feel better, as the infection may return. Keep all follow-up appointments and blood tests as advised by your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects, especially heart failure and liver problems. Dose adjustment may be needed based on liver and kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy, especially for nail infections. Use effective contraception during treatment and for two months after the last dose.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with certain anesthetic agents. Your doctor may adjust your treatment plan.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain medications used in dentistry, such as midazolam. Your dentist may need to adjust medications.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent fungal infections.
🥗
Keep your skin dry, especially in folds and feet.
😴
Wear breathable clothing and footwear.
💧
Avoid sharing towels, shoes, or nail clippers.
🧘
Manage underlying conditions like diabetes to reduce infection risk.
🌞
Eat a balanced diet to support your immune system.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue in some people. Avoid strenuous exercise if you feel unwell. If you have heart failure, consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Take this medicine with a full meal.
Include probiotics to support gut health if on prolonged therapy.
Avoid grapefruit juice.
Stay well hydrated.
Limit alcohol intake.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or headache in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it usually does not interfere with daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like liver problems, heart failure symptoms, or severe allergic reactions, stop and seek immediate medical attention. Your doctor will decide if treatment should be discontinued or changed.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of liver injury, heart failure, and peripheral neuropathy. Regular monitoring of liver function and heart health is recommended. Prolonged use can also lead to fungal resistance. It should only be used for as long as necessary under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungals

For mild skin infections, topical creams may be sufficient and have fewer systemic side effects.

Evidence: Well-established
Terbinafine

An alternative oral antifungal for dermatophyte infections, with a different side effect profile.

Evidence: Well-established
Fluconazole

Another oral antifungal for candidiasis and some systemic infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fungal infection, your immune system may be weakened, so discuss vaccination timing with your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, continue your dosing schedule as close to the usual time as possible. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with toenail fungus
He was prescribed this medicine in pulse doses for his thickened, discolored toenails. He took it with a full meal as directed and avoided alcohol. After three months, his nails began to grow clear. He reported mild stomach upset initially, which resolved when he took it with food.
💡 Lesson: Taking this medicine with food improves tolerability and absorption. Complete the full course for nail infections, as results take months.
👤 A 32-year-old woman with recurrent vaginal candidiasis
She was given this medicine for a week. She experienced nausea and headache, which were mild. She was advised to use contraception during treatment. Her symptoms resolved, and she was advised on lifestyle changes to prevent recurrence.
💡 Lesson: This medicine is effective for candidiasis, but side effects like nausea can occur. Contraception is important during treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in skin infections may be seen within 1-2 weeks. Nail infections may take several months to clear completely.

Q: Can I take this medicine with food?

A: Yes, take it with a full meal to improve absorption and reduce stomach upset.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol, grapefruit juice, and antacids within 2 hours of this medicine. Also avoid certain drugs like statins and midazolam.

Q: Is it safe during pregnancy?

A: It is not recommended during pregnancy, especially for nail infections. Consult your doctor if you are pregnant or planning to become pregnant.

Q: Can I stop taking it when I feel better?

A: No, complete the full course as prescribed to prevent recurrence of infection.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • How long does it take to work?

🔄 Substitutes for it pride 100mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Itraconazole can cure any fungal infection quickly.
    Fact: Itraconazole is effective for many fungal infections but requires correct diagnosis and appropriate duration. Some infections need months of treatment.
  • Myth: You can stop taking itraconazole once symptoms improve.
    Fact: Stopping early can lead to recurrence of infection. Always complete the full course as prescribed.
  • Myth: Itraconazole is safe for everyone.
    Fact: Itraconazole has significant interactions and contraindications, especially in heart failure and with certain drugs. It requires a prescription and monitoring.

🔄 Alternative Options

Generic Alternatives

  • Itraconazole 100 mg capsule

Brand Alternatives

  • It-mac 100 capsule

📊 Comparison with Similar Medicines

[{"medicine":"Itraconazole","class":"Triazole antifungal","common_uses":"Dermatophytosis, onychomycosis, candidiasis, systemic mycoses","route":"Oral","key_side_effects":"Nausea, headache, liver injury, heart failure"},{"medicine":"Fluconazole","class":"Triazole antifungal","common_uses":"Candidiasis, cryptococcosis","route":"Oral, IV","key_side_effects":"Nausea, headache, liver injury"},{"medicine":"Terbinafine","class":"Allylamine antifungal","common_uses":"Dermatophytosis, onychomycosis","route":"Oral, topical","key_side_effects":"Headache, GI upset, taste disturbance, liver injury"}]

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