davaindia itraconazole 100mg capsule - Itraconazole (100mg) medicine

davaindia itraconazole 100mg capsule

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Itraconazole (100mg)
🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is davaindia itraconazole 100mg capsule used for?

This medicine contains Itraconazole (100mg) and is used to treat OPHTHAL. Inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis and disrupting funga. Always consult your doctor before use.

  • Generic Name: Itraconazole
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 davaindia itraconazole 100mg capsule Uses & Benefits

Onychomycosis, dermatophytosis, candidiasis, histoplasmosis, blastomycosis, aspergillosis.

Off-label uses: Coccidioidomycosis, sporotrichosis, chromoblastomycosis, prophylaxis in immunocompromised patients.

📋 Drug Information

Generic Name(s)Itraconazole
Brand NameAlcros 100 Capsule
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; absorption is enhanced when taken with food.
DistributionWidely distributed in body tissues, including skin, nails, and adipose tissue.
Protein Binding99.8% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via CYP3A4 to active metabolite hydroxyitraconazole.
Half-Life21-25 hours (itraconazole); 12-15 hours (hydroxyitraconazole)
ExcretionPrimarily excreted in feces (40%) and urine (35%) as metabolites.
BioavailabilityApproximately 55% (fasting); increased to 100% with food.
Onset of Action1-2 weeks for therapeutic effect in fungal infections.
Peak Plasma Time4-6 hours after oral administration.
Duration of ActionUp to 2-3 weeks after discontinuation due to tissue accumulation.

How It Works

Inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.

Mechanism Steps

1Itraconazole enters fungal cell via diffusion.
2Binds to heme iron of fungal CYP450 14α-demethylase.
3Inhibits conversion of lanosterol to ergosterol.
4Depletes ergosterol in fungal cell membrane.
5Accumulates toxic 14α-methyl sterols.
6Disrupts membrane integrity and function.
7Leads to fungal cell death (fungistatic).

💡 How to Take davaindia itraconazole 100mg capsule

Follow your doctor's prescription exactly.

⚠️ Side Effects of davaindia itraconazole 100mg capsule

✅ Common Side Effects

Nausea
Abdominal pain
Diarrhea
Headache
Dizziness
Rash

🚨 Serious Side Effects

Hepatotoxicity
Congestive heart failure
QT prolongation
Torsades de pointes
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Peripheral neuropathy
Adrenal suppression
Hypokalemia
Gynecomastia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate Increased INR and bleeding risk
Simvastatin Major Increased risk of rhabdomyolysis
Midazolam Major Prolonged sedation and respiratory depression

🚨 Major Interactions

  • CYP3A4 substrates (e.g., midazolam, triazolam)
  • HMG-CoA reductase inhibitors (e.g., simvastatin, lovastatin)
  • Ergot alkaloids
  • Cisapride
  • Pimozide
  • Quinidine
  • Dofetilide
  • Lovastatin
  • Simvastatin

⚡ Moderate Interactions

  • Warfarin
  • Oral hypoglycemics
  • Calcium channel blockers
  • Digoxin
  • Cyclosporine
  • Tacrolimus
  • Sirolimus
  • Carbamazepine
  • Phenytoin
  • Rifampin
  • Isoniazid
  • Antacids
  • H2 blockers
  • Proton pump inhibitors

🍷 Alcohol Interaction

Avoid alcohol due to potential hepatotoxicity.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to itraconazole or excipients; concomitant use with CYP3A4 substrates with narrow therapeutic index; ventricular dysfunction; pregnancy (category C).

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Supportive care; no specific antidote; gastric lavage if recent; monitor liver function and ECG.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

🔄 Substitutes for davaindia itraconazole 100mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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