Vasoprin 60 mg/75 mg Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is ismorin 60 mg/75 mg capsule used for?
This medicine is a combination of Isosorbide Mononitrate and Aspirin used to prevent and treat angina and reduce the risk of heart attack and stroke. It works by widening blood vessels and preventing blood clots.
- Generic Name: Isosorbide Mononitrate (60mg) + Aspirin (75mg)
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ismorin 60 mg/75 mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) के इलाज और रोकथाम के लिए इस्तेमाल की जाती है। यह दिल के दौरे और स्ट्रोक के खतरे को कम करने में भी मदद करती है। यह रक्त वाहिकाओं को फैलाकर और रक्त के थक्के बनने से रोककर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा और मतली शामिल हैं। गंभीर दुष्प्रभावों में गंभीर निम्न रक्तचाप, जीआई रक्तस्राव और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें। अन्य दवाओं के साथ लेने से पहले डॉक्टर से सलाह लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। दवा को ठंडी और सूखी जगह पर रखें।
💊 ismorin 60 mg/75 mg capsule Uses & Benefits
[{"condition":"Angina pectoris","description":"Used for the prevention and treatment of angina attacks by reducing cardiac workload and improving coronary blood flow.","evidence":"Well-established"},{"condition":"Secondary prevention of myocardial infarction","description":"Aspirin component helps prevent recurrent heart attacks in patients with a history of cardiovascular events.","evidence":"Well-established"},{"condition":"Secondary prevention of stroke","description":"Low-dose aspirin reduces the risk of recurrent ischemic stroke.","evidence":"Well-established"},{"condition":"Coronary artery disease","description":"Used in combination to manage symptoms and prevent complications in patients with coronary artery disease.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label to reduce the risk of preeclampsia in high-risk pregnancies.","evidence":"Limited"},{"condition":"Prevention of colorectal cancer","description":"Aspirin has been studied for chemoprevention of colorectal cancer, but this is not a standard indication.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Myocardial infarction prevention, Stroke prevention
📋 Drug Information
| Generic Name(s) | Isosorbide Mononitrate (60mg) + Aspirin (75mg) |
| Brand Name | ismorin 60 mg/75 mg capsule |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Isosorbide Mononitrate acts by releasing nitric oxide, which activates guanylate cyclase, leading to increased cyclic GMP levels. This results in relaxation of vascular smooth muscle, particularly in veins, causing vasodilation and reduced preload. Aspirin irreversibly inhibits cyclooxygenase-1 (COX-1) and COX-2 enzymes, thereby reducing the synthesis of thromboxane A2, a potent platelet aggregator and vasoconstrictor. The combined effect reduces cardiac workload and prevents thrombus formation.
Mechanism Steps
💡 How to Take ismorin 60 mg/75 mg capsule
Strength: Tablet containing Isosorbide Mononitrate 60 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily or as directed by your physician. The dose may be adjusted based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially hypotension and dizziness. Dose adjustment may be necessary. Consult your doctor. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be required. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be required. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (60 mg isosorbide mononitrate + 75 mg aspirin) or as prescribed by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ismorin 60 mg/75 mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Warfarin | Major | |
| Ibuprofen | Major | |
| Lisinopril | Moderate | |
| Prednisone | Moderate | |
| Antacid | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)
- Anticoagulants (e.g., warfarin)
- Other NSAIDs
⚡ Moderate Interactions
- Antihypertensives
- Corticosteroids
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine as it can potentiate the blood pressure-lowering effect and increase the risk of gastrointestinal bleeding.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nitrates or aspirin","Severe hypotension","Active bleeding disorders","Severe liver or kidney disease","Concurrent use of phosphodiesterase-5 inhibitors","History of asthma induced by aspirin or NSAIDs"]
⚠️ Warnings & Precautions
["Avoid abrupt discontinuation of isosorbide mononitrate as it may cause rebound angina.","Use with caution in patients with glaucoma or increased intracranial pressure.","Aspirin may cause gastrointestinal bleeding; use with caution in patients with peptic ulcer disease.","Avoid alcohol consumption.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe hypotension, headache, flushing, dizziness, and tachycardia. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Avoid alcohol while taking this medicine as it can increase the risk of low blood pressure and gastrointestinal bleeding. Inform your doctor about all other medications you are taking, especially blood thinners, other nitrates, and erectile dysfunction drugs. Do not use this medicine if you are pregnant or breastfeeding without medical advice. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to hypotension and dizziness. Dose adjustment and close monitoring are advised.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. This medicine may not be safe during pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon about this medicine before surgery. It may need to be stopped temporarily due to bleeding risk.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you, as it may cause dizziness or low blood pressure.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most daily activities if taken as prescribed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use may lead to tolerance to nitrates, requiring dose adjustment or a nitrate-free interval. Aspirin long-term use increases risk of gastrointestinal bleeding. Regular monitoring of blood pressure, renal function, and signs of bleeding is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress management can complement medicine for heart health.
Evidence: Well-establishedBeta-blockers or calcium channel blockers may be alternatives or additions.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. Consult your doctor for routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, consult your doctor for dose adjustment. Keep enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Isosorbide Mononitrate starts working within 30-60 minutes, while Aspirin's antiplatelet effect begins within 30-60 minutes. Full benefits may take days to weeks.
A: No, do not stop without consulting your doctor. Abrupt discontinuation can worsen angina.
🤔 Common Patient Concerns
🔄 Substitutes for ismorin 60 mg/75 mg capsule
View AllAlternative brands with exact same active ingredient:
-
monosprin 60 capsule srSun Pharmaceutical Industries Ltd ₹22.25 45.4% CHEAPER
-
nitroprin 60 mg/75 mg tabletLife Medicare & Biotech Pvt Ltd ₹38.75 5% CHEAPER
-
isoloprin 60 mg/75 mg capsuleTorrent Pharmaceuticals Ltd ₹39.59 2.9% CHEAPER
-
vasoprin 60 mg/75 mg tabletTorrent Pharmaceuticals Ltd ₹39.84 2.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: It is safe to stop this medicine suddenly.
Fact: Abrupt discontinuation can worsen angina. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Isosorbide Mononitrate + Aspirin combination generics
Brand Alternatives
- Vasoprin 60 mg/75 mg tablet