insumet 1000mg tablet sr - Metformin (1000mg) medicine

Glycomet 1gm Tablet SR: Comprehensive Medicine Guide

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🏭 Cadila Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Muscle pain or weakness
  • Difficulty breathing or shortness of breath
  • Severe abdominal pain
  • Extreme fatigue or unusual sleepiness
  • Irregular heartbeat or palpitations
  • Yellowing of skin or eyes
  • Decreased urine output
  • Signs of hypoglycemia: shakiness, sweating, confusion, fast heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is insumet 1000mg tablet sr used for?

This medicine is a sustained-release tablet containing Metformin 1000 mg, used to treat type 2 diabetes by lowering blood sugar levels. It works by reducing glucose production in the liver, decreasing glucose absorption from the intestines, and improving insulin sensitivity. It is taken orally, usually once daily with the evening meal.

  • Generic Name: Metformin (1000mg)
  • Manufacturer: Cadila Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 insumet 1000mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा मेटफॉर्मिन 1000 मिलीग्राम का सस्टेन्ड-रिलीज़ टैबलेट है, जिसका उपयोग टाइप 2 डायबिटीज़ (मधुमेह) के इलाज के लिए किया जाता है। यह शरीर में ब्लड शुगर को कम करने में मदद करती है। यह लिवर में ग्लूकोज़ के उत्पादन को कम करती है, आंतों में ग्लूकोज़ के अवशोषण को घटाती है, और शरीर की इंसुलिन के प्रति संवेदनशीलता को बढ़ाती है। यह दवा आमतौर पर रात के खाने के साथ एक बार ली जाती है। इसे डॉक्टर की सलाह के बिना बंद न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, भूख न लगना और मुँह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ हफ्तों में ठीक हो जाते हैं। गंभीर लेकिन दुर्लभ दुष्प्रभावों में लैक्टिक एसिडोसिस हो सकता है, जिसमें मांसपेशियों में दर्द, सांस लेने में कठिनाई, पेट में तेज दर्द, अत्यधिक थकान और अनियमित दिल की धड़कन शामिल हैं। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर रात के खाने के साथ। टैबलेट को पूरा निगलें, चबाएं या तोड़ें नहीं। इस दवा को लेते समय शराब का सेवन न करें या सीमित करें, क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आपको किडनी या लिवर की समस्या है, तो डॉक्टर को बताएं। सर्जरी या कंट्रास्ट डाई वाली जांच से पहले डॉक्टर से सलाह लें। नियमित रूप से ब्लड शुगर की जांच करें और फॉलो-अप अपॉइंटमेंट न भूलें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 insumet 1000mg tablet sr Uses & Benefits

[{"condition":"Type 2 Diabetes Mellitus","description":"First-line therapy to improve glycemic control in adults with type 2 diabetes, especially in overweight patients, when diet and exercise alone are insufficient.","evidence":"Well-established"},{"condition":"Prediabetes","description":"May be prescribed off-label to delay progression to type 2 diabetes in high-risk individuals, but lifestyle changes remain the primary intervention.","evidence":"Moderate"},{"condition":"Polycystic Ovary Syndrome (PCOS)","description":"Used off-label to improve insulin sensitivity and restore menstrual cycles in women with PCOS, though it is not FDA-approved for this indication.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Gestational Diabetes","description":"Sometimes used off-label during pregnancy when insulin is not feasible, but safety data are limited and insulin remains the preferred treatment.","evidence":"Limited"},{"condition":"Weight Management","description":"May cause modest weight loss or prevent weight gain in some patients, but it is not approved as a weight-loss drug.","evidence":"Limited"},{"condition":"Non-Alcoholic Fatty Liver Disease (NAFLD)","description":"Preliminary studies suggest potential benefit in improving liver enzymes and insulin resistance, but evidence is not definitive.","evidence":"Limited"}]

Primary treatment for: Type 2 Diabetes Mellitus

Also treats: Prediabetes, Polycystic Ovary Syndrome (PCOS), Gestational Diabetes

📋 Drug Information

Generic Name(s)Metformin (1000mg)
Brand Nameinsumet 1000mg tablet sr
ManufacturerCadila Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassBiguanides
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization includes metformin in its Model List of Essential Medicines for the treatment of type 2 diabetes.
ICMR GuidelineThe Indian Council of Medical Research recommends metformin as a first-line oral antidiabetic agent for type 2 diabetes, unless contraindicated.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with the evening meal to reduce stomach upset and improve absorption.
2
Swallow the tablet whole; do not crush, chew, or break it.
3
Monitor your blood sugar levels regularly as advised by your doctor.
4
Avoid excessive alcohol consumption while taking this medicine.
5
Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or imaging tests.
6
Report any symptoms of lactic acidosis, such as muscle pain, difficulty breathing, or extreme fatigue, immediately.
7
Your doctor may periodically check your vitamin B12 levels, especially with long-term use.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar (hyperglycemia)
This medicine is commonly prescribed for this.
Likely Use
✅
Frequent urination and excessive thirst
These are symptoms of diabetes that this medicine helps manage.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Joint pain
This medicine is not indicated for joint pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed slowly from the gastrointestinal tract, with peak plasma concentrations reached in about 7 hours for the sustained-release formulation. Food slightly reduces the rate but not the extent of absorption.
DistributionIt is rapidly distributed into body tissues, with highest concentrations in the liver, kidney, and gastrointestinal tract. It does not bind significantly to plasma proteins.
Protein BindingNegligible protein binding.
MetabolismThis medicine is not metabolized by the liver and is excreted unchanged in the urine.
Half-LifeThe elimination half-life is approximately 6.5 hours for the immediate-release form; for the sustained-release form, it may be slightly longer.
ExcretionIt is excreted unchanged in the urine by active tubular secretion and glomerular filtration.
BioavailabilityThe absolute bioavailability of the sustained-release formulation is approximately 50-60% under fasting conditions.
Onset of ActionThe blood sugar-lowering effect begins within a few days, but maximum effect may take up to 2 weeks.
Peak Plasma TimePeak plasma concentration is reached in about 7 hours after oral administration of the sustained-release tablet.
Duration of ActionThe glucose-lowering effect lasts for approximately 24 hours, allowing once-daily dosing.

How It Works

This medicine belongs to the biguanide class. It reduces hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis. It also decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Unlike sulfonylureas, it does not stimulate insulin secretion, so it rarely causes hypoglycemia when used alone.

Mechanism Steps

1
Inhibition of hepatic gluconeogenesis: This medicine reduces the production of glucose in the liver by inhibiting key enzymes involved in gluconeogenesis and glycogenolysis.
2
Decreased intestinal glucose absorption: It slows the absorption of glucose from the gastrointestinal tract, leading to lower postprandial blood sugar spikes.
3
Enhanced insulin sensitivity: It increases the sensitivity of peripheral tissues, especially skeletal muscle and fat, to insulin, promoting greater glucose uptake.
4
Activation of AMPK: This medicine activates AMP-activated protein kinase, which regulates cellular energy metabolism and contributes to its glucose-lowering effects.

💡 How to Take insumet 1000mg tablet sr

Strength: Sustained-release tablet, 1000 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Do not crush, chew, or break the tablet.
4Take it with the evening meal to reduce stomach upset.
5Follow a consistent schedule to maintain blood levels.

Dosage Information

Adult DosageThe usual starting dose of this medicine is 500 mg once daily with the evening meal, which may be increased gradually based on blood sugar levels and tolerability. The maximum recommended dose is 2000 mg per day. For the sustained-release 1000 mg tablet, the typical dose is one tablet once daily with the evening meal. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function. Renal function should be monitored regularly, and the dose should be adjusted accordingly. Dose must be individualized by a qualified clinician.
Renal ImpairmentFor patients with eGFR 30-45 mL/min/1.73 m², this medicine should be used with caution and at reduced doses. It is contraindicated if eGFR is below 30 mL/min/1.73 m². Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentThis medicine should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Dose adjustment may be necessary. Dose must be individualized by a qualified clinician.
Maximum Daily Dose2000 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with the evening meal
Reduces stomach upset and improves tolerability.
Alcohol
Avoid excessive intake
Increases risk of lactic acidosis and hypoglycemia.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of insumet 1000mg tablet sr

✅ Common Side Effects

Nausea (Common (up to 30%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (up to 20%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.
Abdominal discomfort (Common (10-20%))
Usually improves over time. Taking with meals may help.
Metallic taste (Common (5-10%))
This is temporary and usually resolves. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Lactic acidosis (Rare (<0.1%))
Seek immediate medical attention if you experience muscle pain, difficulty breathing, stomach pain, extreme fatigue, or irregular heartbeat.
Vitamin B12 deficiency (Uncommon (5-10% with long-term use))
Your doctor may monitor B12 levels periodically. Report symptoms like tingling in hands or feet, weakness, or anemia.
Hypoglycemia (when used with other diabetes drugs) (Uncommon)
Know the signs: shakiness, sweating, confusion, fast heartbeat. Carry fast-acting sugar. Consult your doctor if episodes occur.

⚠️ Rare Side Effects

Severe allergic reaction (anaphylaxis)
Seek emergency help if you have rash, itching, swelling of face/lips/tongue, or difficulty breathing.
Megaloblastic anemia due to B12 deficiency
Report unusual fatigue, pale skin, or shortness of breath to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Iodinated contrast media Major
Alcohol Major
Diuretics Moderate
NSAIDs Moderate
Corticosteroids Moderate
Cationic drugs Moderate
ACE inhibitors Minor
Beta-blockers Minor

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol
  • Diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, triamterene, trimethoprim, vancomycin)
  • NSAIDs
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol can increase the risk of lactic acidosis and hypoglycemia when taken with this medicine. It is advisable to limit or avoid alcohol consumption while on this medication. Discuss safe limits with your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Lactic acidosis is a rare but serious metabolic complication that can occur due to metformin accumulation. Seek immediate medical attention if you experience symptoms.","Temporarily discontinue this medicine before undergoing radiologic studies with iodinated contrast materials.","Avoid excessive alcohol intake while taking this medicine.","Use with caution in elderly patients, who may have reduced renal function.","Monitor renal function regularly, especially in patients with kidney disease.","This medicine may cause vitamin B12 deficiency with long-term use; periodic monitoring is advised.","Do not use in patients with severe heart failure or unstable cardiac conditions."]

🤱 Lactation Safety

This medicine is excreted in small amounts in breast milk. It is generally considered compatible with breastfeeding, but monitor the infant for signs of hypoglycemia. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can lead to lactic acidosis, which is a medical emergency. Symptoms include severe nausea, vomiting, diarrhea, abdominal pain, muscle pain, difficulty breathing, and extreme fatigue. If overdose is suspected, seek immediate medical attention. Treatment includes supportive care, hemodialysis to remove metformin and correct acidosis, and management of electrolyte imbalances.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, usually once daily with the evening meal to reduce stomach upset and improve absorption. Swallow the tablet whole; do not crush, chew, or break it, as this can release the drug too quickly and increase the risk of side effects. Do not skip meals while taking this medicine, as it can increase the risk of low blood sugar if used with other diabetes medications. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems, heart failure, or if you are scheduled for surgery or imaging tests with contrast dye. Your doctor may ask you to temporarily stop this medicine before such procedures. Regularly monitor your blood sugar levels as advised and keep all follow-up appointments. Do not start or stop any new medication without consulting your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of renal impairment and lactic acidosis. Renal function should be assessed before starting and monitored regularly. Lower doses may be required. Close monitoring of blood sugar and vitamin B12 levels is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine may be continued during pregnancy under medical supervision, but insulin is often preferred. Good blood sugar control before conception is important to reduce risks to the baby.

🏥 Post-Surgery Considerations

This medicine may be temporarily stopped before surgery and restarted after your doctor confirms that renal function is normal. Follow your surgeon's and doctor's instructions regarding when to resume.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but if you are scheduled for a procedure requiring sedation or contrast, your doctor may adjust your medication.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve insulin sensitivity.
🥗
Engage in regular physical activity, such as brisk walking or swimming, for at least 30 minutes most days.
😴
Follow a balanced diet rich in fiber, lean proteins, and healthy fats.
💧
Limit intake of refined sugars and processed foods.
🧘
Monitor your blood sugar levels regularly as advised.
🌞
Get adequate sleep and manage stress to help control blood sugar.

🏋️ Exercise Considerations

Exercise is beneficial for managing diabetes, but if you take this medicine with other glucose-lowering drugs, be aware of the risk of hypoglycemia during or after exercise. Carry a source of fast-acting sugar with you. Stay hydrated, especially during intense workouts. Consult your doctor before starting a new exercise regimen.

🥗 Diet Recommendations

Include high-fiber foods like whole grains, vegetables, and legumes.
Choose lean protein sources such as fish, poultry, and tofu.
Limit sugary drinks and snacks.
Eat regular meals and avoid skipping meals.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine generally does not impair your ability to drive or operate machinery. However, if you experience hypoglycemia (which is more likely if combined with other diabetes drugs), it can affect your concentration. Be aware of the signs and carry fast-acting sugar. Inform your employer about your condition if necessary.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like lactic acidosis, your doctor will advise you to stop. In certain situations, such as before surgery or contrast imaging, your doctor may temporarily discontinue it. Always follow your doctor's guidance.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing type 2 diabetes. However, it may lead to vitamin B12 deficiency, so periodic monitoring is recommended. Renal function should be checked regularly, especially in elderly patients. Lactic acidosis is a rare but serious risk, particularly in patients with kidney or liver disease. Regular follow-up with your doctor is essential to monitor for these effects and adjust treatment as needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are cornerstone treatments for type 2 diabetes and can complement or reduce the need for medication.

Evidence: Well-established
Other oral antidiabetic drugs

Sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, etc., may be used alone or in combination.

Evidence: Well-established
Insulin therapy

May be necessary if oral agents fail to control blood sugar.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, maintaining up-to-date vaccinations, including influenza and pneumococcal vaccines, is recommended for people with diabetes.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip and a few extra days in case of delays. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with newly diagnosed type 2 diabetes
He was started on this medicine 1000 mg once daily with dinner. Initially, he experienced mild nausea and diarrhea, but these improved after two weeks. His blood sugar levels gradually normalized, and he lost 3 kg over three months. He emphasized the importance of taking the tablet with food and not skipping meals.
💡 Lesson: Gastrointestinal side effects are common initially but often subside. Taking the medicine with food and adhering to the prescribed schedule improves tolerability and outcomes.
👤 A 45-year-old woman with PCOS and insulin resistance
She was prescribed this medicine off-label to help with insulin resistance and irregular periods. After three months, her menstrual cycles became more regular, and her energy levels improved. She also noticed a reduction in sugar cravings. She stressed the need for regular follow-up and blood tests.
💡 Lesson: This medicine can be beneficial for conditions like PCOS, but it should be used under medical supervision with regular monitoring.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within a few days, but it may take up to 2 weeks to see the full effect. Regular monitoring will help track your progress.

Q: Can I take this medicine with other diabetes medications?

A: Yes, it is often used in combination with other diabetes drugs, but only under your doctor's supervision. Combining with certain drugs may increase the risk of hypoglycemia.

Q: What should I do if I experience side effects?

A: Mild side effects like nausea or diarrhea often improve over time. Taking the medicine with food can help. If side effects are severe or persistent, contact your doctor.

Q: Can I stop taking this medicine if my blood sugar is normal?

A: No, do not stop without consulting your doctor. This medicine is usually a long-term treatment. Stopping abruptly can cause blood sugar to rise.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Does it cause weight gain?

🔄 Substitutes for insumet 1000mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is insulin.
    Fact: This medicine is not insulin. It is an oral medication that helps lower blood sugar by improving insulin sensitivity and reducing glucose production.
  • Myth: This medicine can be taken without food.
    Fact: It should be taken with food, preferably the evening meal, to reduce stomach upset and improve tolerability.
  • Myth: This medicine causes weight gain.
    Fact: This medicine is weight-neutral or may cause modest weight loss, unlike some other diabetes medications.
  • Myth: This medicine can be stopped once blood sugar is normal.
    Fact: This medicine is usually a long-term treatment. Stopping it without medical advice can lead to uncontrolled blood sugar.

🔄 Alternative Options

Generic Alternatives

  • Metformin 1000 mg sustained-release tablet

Brand Alternatives

  • Glycomet 1gm Tablet SR
  • Gluconorm 1gm Tablet SR
  • Zomet 1gm Tablet SR
  • Carbophage 1gm Tablet SR

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Biguanide","primary_use":"Type 2 diabetes","route":"Oral","common_side_effects":"GI upset, metallic taste"},{"medicine":"Glimepiride","class":"Sulfonylurea","primary_use":"Type 2 diabetes","route":"Oral","common_side_effects":"Hypoglycemia, weight gain"},{"medicine":"Sitagliptin","class":"DPP-4 inhibitor","primary_use":"Type 2 diabetes","route":"Oral","common_side_effects":"Headache, nasopharyngitis"}]

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