hyocimax plus tablet - Hyoscine butylbromide (10mg) + Paracetamol (500mg) medicine

Hyocimax Plus Tablet: Complete Information

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Consult your doctor for guidance. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is hyocimax plus tablet used for?

This medicine is a combination of hyoscine butylbromide and paracetamol used to treat abdominal cramps and pain. It works by relaxing smooth muscles and reducing pain.

  • Generic Name: Hyoscine butylbromide (10mg) + Paracetamol (500mg)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hyocimax plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पेट की ऐंठन, मासिक धर्म के दर्द, और आंतों की समस्याओं में राहत देने के लिए इस्तेमाल की जाती है। यह मांसपेशियों को आराम देकर दर्द कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, कब्ज, धुंधली दृष्टि, चक्कर आना और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लिवर की समस्या, या पेशाब रोकने जैसी स्थिति हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब न पिएं। अगर आपको ग्लूकोमा, मायस्थेनिया ग्रेविस, या लिवर/किडनी की बीमारी है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 hyocimax plus tablet Uses & Benefits

[{"condition":"Abdominal cramps","description":"Relieves spasmodic pain in the gastrointestinal tract by relaxing smooth muscles.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Reduces uterine spasms and associated pain during menstruation.","evidence":"Well-established"},{"condition":"Irritable bowel syndrome (IBS)","description":"Helps alleviate abdominal pain and cramping associated with IBS.","evidence":"Moderate"},{"condition":"Biliary colic","description":"Provides relief from pain due to gallstones or biliary spasm.","evidence":"Limited"},{"condition":"Urinary tract spasms","description":"May be used to relieve spasms in the urinary tract.","evidence":"Limited"}]

Off-label uses: [{"condition":"Painful bladder syndrome","description":"Sometimes used to relieve bladder spasms and pain.","evidence":"Limited"},{"condition":"Dysmenorrhea resistant to NSAIDs","description":"May be used when NSAIDs are contraindicated or ineffective.","evidence":"Limited"}]

Primary treatment for: Abdominal cramps

Also treats: Menstrual cramps, Irritable bowel syndrome, Biliary colic

📋 Drug Information

Generic Name(s)Hyoscine butylbromide (10mg) + Paracetamol (500mg)
Brand Namehyocimax plus tablet
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Menstrual pain
This medicine helps relieve uterine spasms.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionHyoscine butylbromide is poorly absorbed from the gastrointestinal tract, with only about 10-20% of an oral dose reaching systemic circulation. Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract.
DistributionHyoscine butylbromide is distributed mainly in the abdominal and pelvic regions, with limited penetration into the central nervous system due to its quaternary structure. Paracetamol is distributed widely throughout body fluids.
Protein BindingHyoscine butylbromide is approximately 80% bound to plasma proteins. Paracetamol has low protein binding (about 10-25%).
MetabolismHyoscine butylbromide undergoes limited metabolism in the liver. Paracetamol is metabolized primarily in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeHyoscine butylbromide: approximately 5 hours. Paracetamol: 2-3 hours.
ExcretionHyoscine butylbromide is excreted mainly in the feces, with a small amount in urine. Paracetamol is excreted in urine as metabolites.
BioavailabilityHyoscine butylbromide: low oral bioavailability (about 10-20%). Paracetamol: high oral bioavailability (about 80-90%).
Onset of ActionHyoscine butylbromide: onset of antispasmodic effect within 15-30 minutes. Paracetamol: onset of analgesia within 30-60 minutes.
Peak Plasma TimeHyoscine butylbromide: 1-2 hours. Paracetamol: 0.5-1 hour.
Duration of ActionHyoscine butylbromide: 4-6 hours. Paracetamol: 4-6 hours.

How It Works

Hyoscine butylbromide is a quaternary ammonium antimuscarinic agent that blocks muscarinic acetylcholine receptors on smooth muscle cells, leading to relaxation of the gastrointestinal and genitourinary smooth muscles. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. The combination provides both antispasmodic and analgesic effects.

Mechanism Steps

1
Antimuscarinic action: Hyoscine butylbromide binds to muscarinic receptors on smooth muscle, preventing acetylcholine from activating them.
2
Smooth muscle relaxation: Blockade of muscarinic receptors leads to decreased intracellular calcium and relaxation of smooth muscle.
3
Central analgesia: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain perception.
4
Antipyretic effect: Paracetamol acts on the hypothalamus to lower fever.

💡 How to Take hyocimax plus tablet

Strength: Tablet containing hyoscine butylbromide 10 mg and paracetamol 500 mg.

1Swallow the tablet whole with a glass of water.
2Take with or without food, but with food if it upsets your stomach.
3Do not crush or chew the tablet.
4Take at the same times each day to maintain consistent levels.
5Do not exceed the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is 1 tablet taken 2 to 3 times daily, depending on the severity of symptoms and the doctor's recommendation. The maximum daily dose should not exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the anticholinergic effects of hyoscine butylbromide. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Paracetamol dose should be reduced or avoided in severe liver disease. Consult a doctor.
Maximum Daily DoseMaximum 6 tablets in 24 hours (3000 mg paracetamol and 60 mg hyoscine butylbromide).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of hyocimax plus tablet

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water or chew sugar-free gum. Consult doctor if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if severe.
Blurred vision (Common (5-10%))
Avoid driving if affected. Usually resolves; consult if persistent.
Dizziness (Common (5-10%))
Avoid sudden movements. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food. Consult doctor if persistent.

🚨 Serious Side Effects

Allergic reactions (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Liver damage (paracetamol overdose) (Rare (<0.1%))
Seek immediate medical attention if symptoms like yellowing of skin or eyes, dark urine, or severe abdominal pain occur.
Urinary retention (Rare (<0.1%))
Consult doctor immediately if unable to urinate.
Palpitations (Rare (<0.1%))
Seek medical advice if persistent or accompanied by chest pain.

⚠️ Rare Side Effects

Confusion
Consult doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency medical care.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Antihistamines Moderate
Tricyclic antidepressants Moderate
Metoclopramide Moderate
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., antihistamines, tricyclic antidepressants)
  • Metoclopramide

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen anticholinergic side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Glaucoma","Myasthenia gravis","Severe liver disease","Hypersensitivity to any component","Urinary retention","Paralytic ileus"]

⚠️ Warnings & Precautions

["Avoid alcohol","Do not exceed recommended dose","Use with caution in elderly","Use with caution in renal or hepatic impairment","May cause drowsiness; avoid driving"]

🤱 Lactation Safety

Hyoscine butylbromide and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe liver damage from paracetamol and anticholinergic symptoms from hyoscine butylbromide. Seek immediate medical attention. Treatment includes activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it increases the risk of liver damage. Do not drive or operate heavy machinery if you feel dizzy or have blurred vision. Inform your doctor if you have glaucoma, myasthenia gravis, liver or kidney disease, or difficulty urinating. Do not take other paracetamol-containing products simultaneously to avoid overdose. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to anticholinergic side effects such as confusion, dry mouth, and urinary retention. Use with caution and lower doses may be required. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery. It may also mask symptoms of complications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications used during dental work.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Eat a balanced diet rich in fiber to prevent constipation.
😴
Stay hydrated by drinking plenty of water.
💧
Practice stress-reducing techniques like yoga or meditation.
🧘
Avoid trigger foods that worsen your symptoms.
🌞
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or fatigued. Light activities like walking are generally safe. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Avoid spicy and oily foods that may irritate the stomach.
Stay well hydrated.
Limit caffeine and alcohol intake.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or blurred vision, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause drowsiness; take caution during work.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms persist beyond 7 days, if you experience any serious side effects, or if you develop new symptoms. Do not stop abruptly without medical advice if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of liver and kidney damage due to paracetamol. Regular monitoring of liver and kidney function is advised if used for extended periods. It is generally recommended for short-term use only.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Heat therapy

Applying a heating pad to the abdomen can help relax muscles and relieve cramps.

Evidence: Well-established
Dietary changes

Avoiding trigger foods and eating a balanced diet can reduce cramping.

Evidence: Moderate
Stress management

Yoga, meditation, and deep breathing can help reduce stress-induced cramps.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before any vaccination if you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat or moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with severe menstrual cramps
She was prescribed this medicine for menstrual pain. She took it as directed and experienced significant relief within an hour. She noted that taking it with food helped avoid stomach discomfort.
💡 Lesson: Taking this medicine with food improves tolerability and ensures better relief.
👤 A 50-year-old man with irritable bowel syndrome
He experienced frequent abdominal cramps. His doctor prescribed this medicine. He found that avoiding alcohol and taking the medicine regularly reduced his symptoms. He also incorporated dietary changes.
💡 Lesson: Combining medication with lifestyle changes enhances overall symptom control.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving cramps within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking it with food reduces the risk of stomach upset.

Q: Is it safe during pregnancy?

A: Consult your doctor before use during pregnancy. The safety profile is not well established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for hyocimax plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Hyocimax plus tablet is a general painkiller for all types of pain.
    Fact: It is specifically for spasmodic pain and cramps, not for all types of pain.
  • Myth: It is safe to take more than the recommended dose for faster relief.
    Fact: Exceeding the dose can cause serious liver damage from paracetamol.

🔄 Alternative Options

Generic Alternatives

  • Hyoscine butylbromide + Paracetamol tablet

Brand Alternatives

  • Buscopan Plus
  • Hyospas Plus

📊 Comparison with Similar Medicines

[{"medicine":"Hyoscine butylbromide + Paracetamol","composition":"Hyoscine butylbromide 10 mg + Paracetamol 500 mg","uses":"Abdominal cramps, menstrual pain","notes":"Antispasmodic + analgesic"},{"medicine":"Dicyclomine + Paracetamol","composition":"Dicyclomine 20 mg + Paracetamol 500 mg","uses":"Abdominal cramps, IBS","notes":"Similar but different antispasmodic"}]

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