Buscopan Plus 10 mg/500 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Fast or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is dolokind spas 10 mg/500 mg tablet used for?
This medicine is a combination of hyoscine butylbromide and paracetamol used to relieve abdominal cramps and pain associated with irritable bowel syndrome and other smooth muscle spasms. It works by relaxing gut muscles and reducing pain.
- Generic Name: Hyoscine butylbromide + Paracetamol
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dolokind spas 10 mg/500 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पेट की ऐंठन और दर्द के इलाज के लिए इस्तेमाल की जाती है। यह हाइओसीन ब्यूटाइलब्रोमाइड और पैरासिटामोल का संयोजन है। यह आंतों की मांसपेशियों को आराम देकर ऐंठन को कम करती है और दर्द को शांत करती है। इसका उपयोग इरिटेबल बाउल सिंड्रोम, मासिक धर्म की ऐंठन, और पित्त या मूत्र पथ की ऐंठन में किया जाता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, कब्ज, धुंधली दृष्टि, चक्कर आना, नींद आना, मतली और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, और यकृत की क्षति हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित मात्रा से अधिक न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे यकृत को नुकसान हो सकता है। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 dolokind spas 10 mg/500 mg tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS) associated abdominal cramps","description":"Relieves abdominal pain and cramping by relaxing smooth muscle in the gut.","evidence":"Well-established"},{"condition":"Functional gastrointestinal disorders with spasm","description":"Reduces spasm-related pain and discomfort in the digestive tract.","evidence":"Moderate"},{"condition":"Menstrual cramps (dysmenorrhea)","description":"Helps relieve uterine cramps and associated pain.","evidence":"Moderate"},{"condition":"Biliary and urinary tract spasms","description":"May be used for spasm-related pain in bile ducts or urinary tract.","evidence":"Limited"}]
Off-label uses: [{"condition":"Renal colic","description":"Sometimes used off-label for pain relief in kidney stones, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome
Also treats: Functional gastrointestinal disorders, Dysmenorrhea, Biliary spasm, Urinary tract spasm
📋 Drug Information
| Generic Name(s) | Hyoscine butylbromide + Paracetamol |
| Brand Name | Buscopan Plus |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Hyoscine butylbromide is a quaternary ammonium antimuscarinic agent that blocks muscarinic acetylcholine receptors on smooth muscle, thereby reducing muscle spasm and motility in the gastrointestinal and genitourinary tracts. Paracetamol acts primarily in the central nervous system to reduce pain and fever, though its exact mechanism is not fully understood. Together, they provide relief from spasm-related pain.
Mechanism Steps
💡 How to Take dolokind spas 10 mg/500 mg tablet
Strength: Each tablet contains hyoscine butylbromide 10 mg and paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally up to three times a day, as needed for relief of cramps and pain. The maximum daily dose should not exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the anticholinergic effects of hyoscine butylbromide. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | The maximum daily dose is 6 tablets (60 mg hyoscine butylbromide and 3000 mg paracetamol) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dolokind spas 10 mg/500 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Tricyclic antidepressants | Major | |
| Antihistamines | Moderate | |
| Metoclopramide | Moderate | |
| Cholestyramine | Moderate | |
| Alcohol | Major |
🚨 Major Interactions
- Other anticholinergic drugs (e.g., tricyclic antidepressants, antihistamines)
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Metoclopramide
- Cholestyramine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may worsen drowsiness or dizziness caused by hyoscine butylbromide.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to hyoscine butylbromide, paracetamol, or any component","Glaucoma","Myasthenia gravis","Pyloric stenosis","Paralytic ileus","Severe liver disease","Severe kidney disease"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of paracetamol to avoid liver damage.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of anticholinergic effects.","Use with caution in patients with liver or kidney disease.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Do not take other paracetamol-containing products concurrently.","Consult doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Hyoscine butylbromide and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose of paracetamol can cause severe liver damage. Seek immediate medical attention even if you feel well. Treatment may include activated charcoal, N-acetylcysteine, and supportive care. Overdose of hyoscine butylbromide may cause anticholinergic symptoms such as dry mouth, blurred vision, palpitations, urinary retention, and confusion. Management is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol while taking this medicine because it can increase the risk of liver damage from paracetamol and worsen drowsiness or dizziness. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have glaucoma, myasthenia gravis, liver disease, kidney disease, or any heart condition. Do not take other paracetamol-containing products while on this medicine to avoid overdose. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the anticholinergic effects of hyoscine butylbromide, such as confusion, urinary retention, and constipation. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. The safety of this medicine during pregnancy has not been fully established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, especially if you have been prescribed other painkillers. Paracetamol may interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or drowsy. Light to moderate exercise is generally safe. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause dry mouth, which can be managed by sipping water.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine should be avoided unless prescribed by a doctor. Prolonged use of paracetamol can increase the risk of liver and kidney damage. Hyoscine butylbromide may cause persistent anticholinergic effects. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods and eating a balanced diet can help reduce cramps.
Evidence: Well-establishedYoga, meditation, and counseling can help reduce stress-related gut symptoms.
Evidence: ModerateGentle exercise and stretching can help relieve muscle tension.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. Consult your doctor for routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving cramps within 15-30 minutes after taking it.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: Consult your doctor before taking this medicine during pregnancy. The safety has not been fully established.
A: Do not take other paracetamol-containing products concurrently. Consult your doctor before taking any other painkillers.
🤔 Common Patient Concerns
🔄 Substitutes for dolokind spas 10 mg/500 mg tablet
View AllAlternative brands with exact same active ingredient:
-
buscopan plus 10 mg/500 mg tabletZydus Cadila ₹55.70 137.6% COSTLIER
-
hyocimax plus tabletZydus Cadila ₹65.00 177.3% COSTLIER
-
betaspas 10mg/500mg tabletBetamax Remedies ₹95.00 305.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for cramping and spasm-related pain, not for all types of pain. - Myth: It is safe to take extra doses if pain persists.
Fact: Taking more than the recommended dose can cause serious liver damage from paracetamol. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided as it increases the risk of liver damage and side effects.
🔄 Alternative Options
Generic Alternatives
- Hyoscine butylbromide + Paracetamol 10 mg/500 mg tablet
Brand Alternatives
- Buscopan Plus 10 mg/500 mg tablet