histaplus tablet - Paracetamol (500mg) + Pseudoephedrine (60mg) medicine

Fastorik Tablet: Complete Medicine Guide

No reviews yet
🏭 Park Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is histaplus tablet used for?

This medicine is a combination of Paracetamol and Pseudoephedrine used for short-term relief of nasal congestion, headache, body ache, and fever associated with cold, allergies, or sinusitis. It works by reducing pain and fever and shrinking nasal blood vessels.

  • Generic Name: Paracetamol (500mg) + Pseudoephedrine (60mg)
  • Manufacturer: Park Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 histaplus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और स्यूडोएफेड्रिन का संयोजन है, जिसका उपयोग सर्दी, एलर्जी और साइनसाइटिस के लक्षणों जैसे नाक बंद होना, सिरदर्द, शरीर दर्द और बुखार से राहत के लिए किया जाता है। यह दवा अल्पकालिक उपयोग के लिए है और इसे डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, मुँह सूखना, बेचैनी, अनिद्रा, चक्कर आना और धड़कन बढ़ना शामिल हैं। यदि आपको गंभीर एलर्जी, पीलिया, या सीने में दर्द हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड या प्रोस्टेट की समस्या है तो डॉक्टर को बताएं। 7 दिनों से अधिक उपयोग न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 histaplus tablet Uses & Benefits

[{"condition":"Common cold","description":"Relieves nasal congestion, headache, body ache, and fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces nasal stuffiness and sneezing due to allergies.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps relieve sinus pressure and congestion.","evidence":"Well-established"},{"condition":"Influenza","description":"Provides symptomatic relief from fever, aches, and nasal congestion.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Eustachian tube dysfunction","description":"Sometimes used to relieve ear pressure during flights or altitude changes.","evidence":"Limited"}]

Primary treatment for: Common cold

Also treats: Allergic rhinitis, Sinusitis, Influenza

📋 Drug Information

Generic Name(s)Paracetamol (500mg) + Pseudoephedrine (60mg)
Brand Namehistaplus tablet
ManufacturerPark Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Monitor your blood pressure if you have hypertension.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
Paracetamol helps reduce fever.
Likely Use
✅
Headache
Paracetamol provides pain relief.
Likely Use
❌
Sore throat
This medicine is not a primary throat reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and almost completely absorbed from the gastrointestinal tract. Pseudoephedrine is also readily absorbed from the gastrointestinal tract.
DistributionParacetamol distributes widely into most body tissues. Pseudoephedrine distributes into body tissues and crosses the placenta and blood-brain barrier.
Protein BindingParacetamol: 10-25%; Pseudoephedrine: Not established from the available information.
MetabolismParacetamol is metabolized in the liver primarily by conjugation with glucuronic acid and sulfate. Pseudoephedrine undergoes minimal hepatic metabolism.
Half-LifeParacetamol: 2-3 hours; Pseudoephedrine: 3-6 hours.
ExcretionParacetamol metabolites are excreted in urine. Pseudoephedrine is excreted largely unchanged in urine.
BioavailabilityParacetamol: 80-100%; Pseudoephedrine: Not established from the available information.
Onset of ActionParacetamol: 30-60 minutes; Pseudoephedrine: 15-30 minutes.
Peak Plasma TimeParacetamol: 0.5-2 hours; Pseudoephedrine: 1-2 hours.
Duration of ActionParacetamol: 4-6 hours; Pseudoephedrine: 4-6 hours.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Paracetamol acts primarily in the central nervous system to inhibit prostaglandin synthesis, which elevates the pain threshold and reduces fever. Pseudoephedrine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing vasoconstriction of nasal mucosal blood vessels, thereby reducing nasal congestion and swelling.

Mechanism Steps

1
Paracetamol action: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain and fever.
2
Pseudoephedrine action: Pseudoephedrine stimulates alpha-adrenergic receptors on nasal blood vessels, causing vasoconstriction and reduced congestion.
3
Combined effect: The combination provides simultaneous relief from pain, fever, and nasal congestion.

💡 How to Take histaplus tablet

Strength: Tablet: Paracetamol 500 mg + Pseudoephedrine 60 mg

1Take this medicine orally with a glass of water.
2Take with food or milk to reduce stomach upset.
3Do not crush or chew the tablet; swallow whole.
4Take exactly as prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 6 to 8 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 7 days without consulting a doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of pseudoephedrine. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseParacetamol: 4000 mg; Pseudoephedrine: 240 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of histaplus tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugarless gum.
Insomnia (Common (5-10%))
Avoid taking close to bedtime.
Restlessness (Common (5-10%))
Usually resolves; consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe hypertension (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, chest pain, or blurred vision.

⚠️ Rare Side Effects

Blood dyscrasias
Report any unusual bleeding, bruising, or infections to your doctor.
Seizures
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Beta-blockers Major
Warfarin Moderate
Tricyclic antidepressants Moderate
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Beta-blockers

⚡ Moderate Interactions

  • Warfarin
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase the risk of liver damage and enhance central nervous system effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe hypertension","Severe coronary artery disease","Use with MAOIs","Hypersensitivity to any component","Severe liver disease"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid alcohol.","Use with caution in patients with heart disease, diabetes, thyroid disorders, or prostate enlargement.","Do not use for more than 7 days without medical advice.","May cause dizziness; avoid driving if affected."]

🤱 Lactation Safety

Paracetamol is considered safe during breastfeeding. Pseudoephedrine may pass into breast milk and can cause irritability in the infant. Consult your doctor before use.

💊 Overdose Management

Seek immediate medical attention. Overdose can cause severe liver damage from paracetamol and severe hypertension from pseudoephedrine. Treatment is symptomatic and supportive. Acetylcysteine may be used as an antidote for paracetamol overdose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid consuming alcohol while taking this medicine, as it can increase the risk of liver damage. If you have high blood pressure, heart disease, diabetes, thyroid problems, or prostate enlargement, inform your doctor before taking this medicine. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the cardiovascular effects of pseudoephedrine. Use with caution and monitor blood pressure regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy or are pregnant. Paracetamol is generally considered safe, but pseudoephedrine should be used with caution.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, especially if you are on other medications or have underlying conditions.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or fatigued while taking this medicine. Stay hydrated during exercise.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine if symptoms persist beyond 7 days or if you experience any serious side effects. Consult your doctor before stopping if you have been on long-term therapy.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of paracetamol can increase the risk of liver damage, and pseudoephedrine can cause cardiovascular effects. Regular monitoring of liver and kidney function may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Saline nasal spray

Provides temporary relief from nasal stuffiness.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your doctor about all medications you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with common cold and nasal congestion
He took this medicine as prescribed and experienced significant relief from congestion and headache within 30 minutes. He was advised to take it with food to avoid stomach upset.
💡 Lesson: Taking this medicine with food improves tolerability and ensures better symptom relief.
👤 A 50-year-old woman with allergic rhinitis
She used this medicine for 3 days and found relief from sneezing and nasal stuffiness. She was cautioned not to exceed the recommended dose due to her mild hypertension.
💡 Lesson: Patients with hypertension should use this medicine with caution and monitor blood pressure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral intake.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for histaplus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: It should not be used for more than 7 days without medical advice.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol + Pseudoephedrine combination tablets

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Paracetamol 500 mg + Pseudoephedrine 60 mg","uses":"Cold, allergy, sinusitis","notes":"Combines analgesic and decongestant"},{"medicine":"Paracetamol + Phenylephrine","composition":"Paracetamol 500 mg + Phenylephrine 10 mg","uses":"Cold, allergy","notes":"Phenylephrine is a less potent decongestant"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory