acne rob 20mg capsule - Isotretinoin (20mg) medicine

acne rob 20mg capsule - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Park Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is acne rob 20mg capsule used for?

Acutret 10 Capsule (Isotretinoin) is used to treat DERMA. It contains Isotretinoin (20mg), which Reduces sebum production, normalizes follicular keratinization, inhibits Propion. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Isotretinoin
  • Manufacturer: Park Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š acne rob 20mg capsule Uses & Benefits

Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.

Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.

๐Ÿ“‹ Drug Information

Generic Name(s)Isotretinoin
Brand NameAcutret 10 Capsule
ManufacturerPark Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- First generation
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed orally with high bioavailability; absorption enhanced with food.
DistributionExtensively distributed; crosses placenta; enters breast milk.
Protein Binding99.9% bound to albumin.
MetabolismHepatic metabolism via CYP450 enzymes to active metabolites (4-oxo-isotretinoin).
Half-Life20-24 hours for parent drug; longer for metabolites.
ExcretionExcreted in urine and feces equally.
Bioavailability25% (increased with food).
Onset of Action1-2 weeks for initial improvement.
Peak Plasma Time3-4 hours.
Duration of ActionTherapeutic effect persists weeks after discontinuation.

How It Works

Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.

Mechanism Steps

1Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in the nucleus.
2Modulates gene transcription involved in cell growth, differentiation, and apoptosis.
3Reduces sebocyte proliferation and sebum production.

๐Ÿ’ก How to Take acne rob 20mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acne rob 20mg capsule

โœ… Common Side Effects

  • Cheilitis
  • Dry skin
  • Xerophthalmia
  • Epistaxis
  • Arthralgia
  • Myalgia
  • Headache
  • Increased triglycerides

๐Ÿšจ Serious Side Effects

  • Pseudotumor cerebri
  • Hepatotoxicity
  • Pancreatitis
  • Depression/suicidal ideation
  • Inflammatory bowel disease
  • Teratogenicity

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Vasculitis
  • Hearing impairment
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tetracyclines Major Increased risk of pseudotumor cerebri
Vitamin A supplements Major Additive toxicity (hypervitaminosis A)
Methotrexate Major Increased hepatotoxicity risk
Oral contraceptives Major Reduced contraceptive efficacy
Phenytoin Moderate Increased phenytoin levels
Corticosteroids Moderate Increased osteoporosis risk
Azole antifungals Moderate Increased retinoid toxicity
Alcohol Minor Increased hepatotoxicity risk
Antacids Minor Reduced isotretinoin absorption

๐Ÿšจ Major Interactions

  • Tetracyclines
  • Vitamin A supplements
  • Methotrexate
  • Oral contraceptives (reduced efficacy)

โšก Moderate Interactions

  • Phenytoin
  • Corticosteroids
  • Antifungals (azole)

โ„น๏ธ Minor Interactions

  • Alcohol
  • Antacids

๐Ÿฝ๏ธ Food Interactions

High-fat meals increase absorption.

๐Ÿท Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acne rob 20mg capsule

View All

Alternative brands with exact same active ingredient (Isotretinoin (20mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install