Lornit 150 Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe abdominal pain or persistent vomiting
- Blood in vomit or black, tarry stools
- Yellowing of the skin or eyes (jaundice)
- Confusion, disorientation, or extreme drowsiness
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is hepaford 150mg tablet used for?
This medicine contains L-Ornithine L-Aspartate 150 mg, used to lower blood ammonia levels in liver conditions like hepatic encephalopathy. It works by supporting the urea cycle and glutamine synthesis. Take it orally with food, as prescribed by your doctor.
- Generic Name: L-Ornithine L-Aspartate (150mg)
- Manufacturer: Leeford Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hepaford 150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लीवर से जुड़ी समस्याओं जैसे हेपेटिक एन्सेफेलोपैथी और क्रोनिक लिवर डिजीज में इस्तेमाल की जाती है। यह खून में अमोनिया के स्तर को कम करने में मदद करती है, जिससे दिमागी कार्यों में सुधार होता है। यह लीवर को सपोर्ट करने और अमोनिया को यूरिया में बदलने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, पेट दर्द, दस्त, सिरदर्द और थकान शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गर्भावस्था या स्तनपान के दौरान इसका उपयोग डॉक्टर की सलाह के बिना न करें। शराब का सेवन बिल्कुल न करें। दवा को बच्चों की पहुंच से दूर रखें। निर्धारित खुराक से अधिक न लें।
💊 hepaford 150mg tablet Uses & Benefits
[{"condition":"Hepatic encephalopathy","description":"This medicine is used as an adjunct to treat hepatic encephalopathy by lowering blood ammonia levels and improving mental status in patients with liver cirrhosis.","evidence":"Well-established"},{"condition":"Chronic liver disease","description":"It is used to support liver function and reduce ammonia levels in patients with chronic liver disease, including cirrhosis.","evidence":"Moderate"},{"condition":"Acute liver injury","description":"Sometimes used as supportive therapy in acute liver injury to help manage hyperammonemia.","evidence":"Limited"}]
Off-label uses: [{"condition":"Hepatic encephalopathy prophylaxis","description":"May be used off-label to prevent episodes of hepatic encephalopathy in patients with advanced liver disease.","evidence":"Limited"},{"condition":"Chronic fatigue associated with liver disease","description":"Occasionally prescribed off-label to improve fatigue in patients with chronic liver conditions.","evidence":"Insufficient"}]
Primary treatment for: Hepatic encephalopathy
Also treats: Chronic liver disease, Cirrhosis, Acute liver injury
📋 Drug Information
| Generic Name(s) | L-Ornithine L-Aspartate (150mg) |
| Brand Name | hepaford 150mg tablet |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Amino acids |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by supplying two amino acids, L-ornithine and L-aspartate, which are key substrates in the urea cycle. L-ornithine is converted to citrulline and then to arginine, which helps in the detoxification of ammonia into urea. L-aspartate participates in the malate-aspartate shuttle and also helps in the synthesis of glutamine from ammonia. Together, they reduce blood ammonia levels, which is beneficial in conditions like hepatic encephalopathy where ammonia accumulation is harmful to the brain.
Mechanism Steps
💡 How to Take hepaford 150mg tablet
Strength: Tablet, 150 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 to 2 tablets (150 mg each) taken two to three times daily, or as directed by your physician. The dose may vary depending on the indication, severity of liver disease, and individual patient factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal or hepatic function, so the dose should be adjusted cautiously. Your doctor may start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. Use with caution and under medical supervision. Not established from the available information for specific dose adjustments. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment, but use under medical supervision. The dose should be individualized based on the severity of liver disease. |
| Maximum Daily Dose | The maximum recommended daily dose is not established from the available information. Follow your doctor's prescription strictly. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hepaford 150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to L-Ornithine L-Aspartate or any component of the tablet","Severe renal impairment (e.g., end-stage renal disease) without medical supervision","Use in children unless prescribed by a pediatrician"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be required.","Avoid alcohol consumption during treatment.","Do not exceed the prescribed dose.","Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not drive or operate heavy machinery if you experience dizziness or drowsiness.","Keep out of reach of children.","Inform your doctor about all other medications you are taking."]
🤱 Lactation Safety
It is not known whether L-Ornithine L-Aspartate is excreted in human breast milk. Caution is advised when used during breastfeeding. Consult your doctor before taking this medicine if you are breastfeeding.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs and provide appropriate care as needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have any kidney or liver problems, as dose adjustments may be necessary. Do not take this medicine if you are allergic to L-Ornithine L-Aspartate or any of its components. This medicine is not recommended during pregnancy or breastfeeding unless clearly needed and prescribed by a doctor. Avoid consuming alcohol while taking this medicine, as it may worsen liver damage and reduce the effectiveness of the treatment. Do not drive or operate heavy machinery if you experience dizziness or drowsiness after taking this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use this medicine beyond its expiry date. Always follow your doctor's instructions regarding dosage and duration of treatment. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney or liver function, so this medicine should be used with caution. Dose adjustment may be necessary. Regular monitoring of renal and hepatic function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It is generally safe, but your doctor may adjust the dose based on your postoperative condition.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your complete medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you have advanced liver disease or feel dizzy or fatigued, avoid strenuous activities and consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you feel alert. Otherwise, it should not significantly affect your daily work life. Inform your employer about your condition if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when to stop based on your condition and response to treatment. If you experience severe side effects, contact your doctor immediately; they may adjust or stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when taken under medical supervision. It is important to have regular monitoring of liver and kidney function. In some patients, prolonged use may lead to electrolyte imbalances. Your doctor will determine the duration of treatment based on your condition. Do not use for longer than prescribed without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A laxative that helps reduce ammonia absorption from the gut.
Evidence: Well-establishedAn antibiotic that reduces ammonia-producing bacteria in the gut.
Evidence: Well-establishedMay be recommended in some cases but should be done under medical supervision.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, patients with liver disease should discuss vaccination against hepatitis A and B with their doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies. Some patients may notice improvement in symptoms within a few days, while others may take weeks. Follow your doctor's advice and attend regular check-ups.
A: Yes, it is often prescribed with other medicines like lactulose or rifaximin. However, always inform your doctor about all medicines you are taking to avoid interactions.
A: This medicine is generally safe, but if you have kidney problems, your doctor may adjust the dose. Regular monitoring may be needed.
A: Do not stop without consulting your doctor. Stopping suddenly may cause your ammonia levels to rise and symptoms to return.
🤔 Common Patient Concerns
🔄 Substitutes for hepaford 150mg tablet
View AllAlternative brands with exact same active ingredient:
-
lorni-s 150mg tabletSidhbali Formulations ₹56.25 48.9% CHEAPER
-
olson 150mg tabletZytras Life Sciences ₹64.69 41.2% CHEAPER
-
hepmend 150mg tabletEmcure Pharmaceuticals Ltd ₹69.56 36.8% CHEAPER
-
hepastar 150mg tabletInvision Medi Sciences Pvt Ltd ₹79.69 27.6% CHEAPER
-
royace liv 150mg tabletPHC Healthcare Pvt Ltd ₹141.48 28.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Lornit 150 can cure liver cirrhosis.
Fact: This medicine does not cure cirrhosis; it helps manage symptoms and complications like high ammonia levels. - Myth: You can stop taking Lornit 150 once you feel better.
Fact: You should only stop if your doctor advises, as stopping suddenly may worsen your condition. - Myth: Lornit 150 is a vitamin supplement.
Fact: It is not a vitamin; it is a medicine used for specific liver conditions.
🔄 Alternative Options
Generic Alternatives
- L-Ornithine L-Aspartate 150 mg tablet (various manufacturers)
Brand Alternatives
- Lornit 150 tablet