Dericip 77mg/23mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe nausea or vomiting
- Irregular or rapid heartbeat
- Seizures
- Difficulty breathing or chest tightness
- Severe headache with visual changes
- Swelling of face, lips, or throat
- Blood in vomit or stool
If experiencing severe symptoms, call emergency services immediately.
What is graphyllin tablet used for?
This medicine is a bronchodilator combination used to treat asthma and COPD. It works by relaxing airway muscles to make breathing easier. Take it exactly as prescribed, usually 2-3 times daily with food.
- Generic Name: Etofylline (77mg) + Theophylline (23mg)
- Manufacturer: Gracure Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 graphyllin tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोफिलिन और थियोफिलिन का संयोजन है, जिसका उपयोग अस्थमा, क्रोनिक ब्रोंकाइटिस और सीओपीडी जैसी सांस की बीमारियों में किया जाता है। यह वायुमार्ग की मांसपेशियों को आराम देकर सांस लेने में मदद करती है। इसे डॉक्टर के निर्देशानुसार नियमित रूप से लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, सिरदर्द, बेचैनी और दिल की धड़कन बढ़ना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि दिल की धड़कन अनियमित हो, दौरा पड़े या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। खाने के साथ लें। शराब और कैफीन से बचें। यदि आपको हृदय, यकृत या गुर्दे की समस्या है तो डॉक्टर को बताएं।
💊 graphyllin tablet Uses & Benefits
[{"condition":"Asthma","description":"Helps prevent and control asthma symptoms by relaxing airway muscles.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to relieve bronchospasm and improve breathing in chronic bronchitis.","evidence":"Well-established"},{"condition":"COPD","description":"May be used as a bronchodilator in chronic obstructive pulmonary disease.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Apnea of prematurity","description":"Sometimes used off-label in premature infants, but not for this formulation.","evidence":"Limited"}]
Primary treatment for: Asthma
Also treats: Chronic bronchitis, COPD
📋 Drug Information
| Generic Name(s) | Etofylline (77mg) + Theophylline (23mg) |
| Brand Name | graphyllin tablet |
| Manufacturer | Gracure Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting phosphodiesterase enzymes, which leads to increased levels of cyclic AMP in bronchial smooth muscle cells. This causes relaxation of the muscles around the airways, resulting in bronchodilation. Additionally, it blocks adenosine receptors, which contributes to its bronchodilator and mild anti-inflammatory effects.
Mechanism Steps
💡 How to Take graphyllin tablet
Strength: Each tablet contains etofylline 77 mg and theophylline 23 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, or as directed by your physician. Dosage may be adjusted based on clinical response and serum theophylline levels. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses due to reduced clearance. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose reduction may be required. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed 3 tablets (231 mg etofylline and 69 mg theophylline) unless otherwise directed by a physician. Individual dosing must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of graphyllin tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Propranolol | Major | |
| Phenytoin | Moderate | |
| Cimetidine | Moderate | |
| Erythromycin | Moderate | |
| Rifampicin | Moderate | |
| Oral contraceptives | Moderate | |
| Allopurinol | Minor | |
| Aminoglutethimide | Minor | |
| Ketoconazole | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Propranolol
⚡ Moderate Interactions
- Phenytoin
- Cimetidine
🍷 Alcohol Interaction
Alcohol may increase the risk of side effects such as nausea, headache, and rapid heart rate. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to etofylline, theophylline, or any component of the formulation","Active peptic ulcer disease","Uncontrolled seizure disorders","Severe cardiac arrhythmias","Acute porphyria"]
⚠️ Warnings & Precautions
["Use with caution in patients with heart disease, hypertension, or hyperthyroidism.","May impair ability to drive or operate machinery due to dizziness or restlessness.","Avoid excessive caffeine intake.","Do not exceed prescribed dose; toxicity can occur.","Use with caution in elderly patients and those with liver or kidney impairment.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
This medicine passes into breast milk and may cause irritability or insomnia in the infant. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose can cause severe nausea, vomiting, seizures, and cardiac arrhythmias. Seek emergency medical attention immediately. Treatment is supportive and symptomatic; there is no specific antidote. Gastric lavage may be considered if recent ingestion. Monitor vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not crush or chew the tablet; swallow it whole with water. Avoid alcohol and caffeine while taking this medicine as they can increase side effects. Inform your doctor if you have heart, liver, or kidney problems. Do not start or stop this medicine without consulting your doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine and may require lower doses. Regular monitoring of heart rate and theophylline levels is advised.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy. This medicine should be used during pregnancy only if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increase heart rate during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activity in cold or polluted air. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or restlessness in some people. Avoid driving or operating heavy machinery until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use may require periodic monitoring of theophylline levels, heart rate, and liver function. Tolerance to the bronchodilator effect is rare. Do not stop suddenly without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement or be an alternative for asthma control.
Evidence: Well-establishedOral medications for asthma prophylaxis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor about flu and pneumonia vaccines, which are recommended for people with chronic respiratory diseases.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 2 hours after taking a dose.
A: Yes, taking it with food helps reduce stomach upset.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for graphyllin tablet
View AllAlternative brands with exact same active ingredient:
-
zeriphylline tabletHealthy Life Pharma Pvt Ltd ₹2.22 11.2% CHEAPER
-
agrophyllin 77mg/23mg tabletAgron Remedies Pvt Ltd ₹2.24 10.4% CHEAPER
-
euroder 77mg/23mg tabletEuro Biogenics ₹3.20 28% COSTLIER
-
deripen 77mg/23mg tabletMorepen Laboratories Ltd ₹4.22 68.8% COSTLIER
-
dericip 77mg/23mg tabletCipla Ltd ₹5.92 136.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used as a rescue inhaler for sudden attacks.
Fact: This medicine is for maintenance therapy, not for acute attacks. Use a rescue inhaler for sudden symptoms. - Myth: It is safe to take extra doses if breathing is difficult.
Fact: Taking extra doses can cause serious side effects. Follow your doctor's instructions exactly.
🔄 Alternative Options
Generic Alternatives
- Etofylline + Theophylline tablet
Brand Alternatives
- Dericip 77mg/23mg tablet