Dapanova M 5mg/500mg Tablet: Comprehensive Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or rapid breathing
- Severe abdominal pain or stomach discomfort
- Unusual muscle pain or weakness
- Dizziness or lightheadedness
- Irregular heartbeat
- Severe pain, redness, or swelling in the genital area
- Decreased urine output
- Yellowing of skin or eyes
- Signs of hypoglycemia (shakiness, sweating, confusion)
If experiencing severe symptoms, call emergency services immediately.
What is glyfloz-m 5mg/500mg tablet er used for?
This medicine is a combination of dapagliflozin and metformin used to treat type 2 diabetes. It helps lower blood sugar by increasing glucose excretion in urine and reducing glucose production in the liver. It is taken orally with meals.
- Generic Name: Dapagliflozin (5mg) + Metformin (500mg)
- Manufacturer: Chemo Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 glyfloz-m 5mg/500mg tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में ब्लड शुगर को कंट्रोल करने में मदद करती है। इसमें डापाग्लिफ्लोज़िन और मेटफॉर्मिन दो दवाएं होती हैं। डापाग्लिफ्लोज़िन किडनी के जरिए शुगर को यूरिन से बाहर निकालता है, जबकि मेटफॉर्मिन लिवर में शुगर बनने को कम करता है और शरीर में इंसुलिन के असर को बढ़ाता है। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए। इसे खाने के साथ लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में जननांग में फंगल इन्फेक्शन, यूरिन इन्फेक्शन, जी मिचलाना, दस्त, पेट में गड़बड़ी और सिरदर्द शामिल हैं। गंभीर साइड इफेक्ट्स में डायबिटिक कीटोएसिडोसिस, लैक्टिक एसिडोसिस और किडनी की समस्या हो सकती है। अगर आपको सांस लेने में तकलीफ, पेट में तेज दर्द, मांसपेशियों में दर्द, चक्कर आना या दिल की धड़कन अनियमित लगे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे खाने के साथ लें ताकि पेट में गड़बड़ी न हो। दिनभर पर्याप्त पानी पिएं। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आपको किडनी या लिवर की समस्या है तो डॉक्टर को बताएं। ब्लड शुगर की नियमित जांच कराएं। किसी भी तरह के इन्फेक्शन के लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
💊 glyfloz-m 5mg/500mg tablet er Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Weight management","description":"Dapagliflozin component may promote modest weight loss, but this is not an approved indication.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease","description":"Some studies suggest potential benefit, but not an approved use.","evidence":"Investigational"}]
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Obesity, Hypertension, Dyslipidemia
📋 Drug Information
| Generic Name(s) | Dapagliflozin (5mg) + Metformin (500mg) |
| Brand Name | glyfloz-m 5mg/500mg tablet er |
| Manufacturer | Chemo Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Dapagliflozin inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules, reducing glucose reabsorption and increasing urinary glucose excretion. Metformin decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Mechanism Steps
💡 How to Take glyfloz-m 5mg/500mg tablet er
Strength: Tablet containing dapagliflozin 5 mg and metformin hydrochloride 500 mg.
Dosage Information
| Adult Dosage | The usual starting dose is one tablet taken orally once daily with meals. The dose may be increased based on blood sugar levels and tolerability. The maximum recommended dose is one tablet twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Renal function should be monitored regularly. Dose adjustment may be needed based on renal function. |
| Renal Impairment | Not recommended in patients with eGFR <30 mL/min/1.73 m2. Dose adjustment may be needed for eGFR 30-45 mL/min/1.73 m2. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Not recommended in severe hepatic impairment. |
| Maximum Daily Dose | One tablet twice daily (dapagliflozin 10 mg + metformin 1000 mg total daily dose). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of glyfloz-m 5mg/500mg tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Contrast media | Major | |
| Alcohol | Major | |
| Diuretics | Moderate | |
| Insulin | Moderate | |
| Sulfonylureas | Moderate | |
| Cationic drugs | Moderate | |
| Nifedipine | Minor |
🚨 Major Interactions
- Contrast media (iodinated)
- Alcohol
⚡ Moderate Interactions
- Diuretics
- Insulin or sulfonylureas
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
🍷 Alcohol Interaction
Alcohol should be avoided or limited while taking this medicine because it can increase the risk of lactic acidosis, a rare but serious complication of metformin. Alcohol can also cause unpredictable changes in blood sugar levels.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Lactic acidosis: Rare but serious. Discontinue and seek medical help if suspected.","Diabetic ketoacidosis: May occur even with normal blood sugar. Monitor for symptoms.","Renal impairment: Dose adjustment may be needed. Monitor renal function.","Hypotension: May occur due to volume depletion. Monitor blood pressure.","Genital mycotic infections: Maintain hygiene. Report symptoms.","Vitamin B12 deficiency: Long-term metformin use may cause deficiency. Monitor levels.","Hypoglycemia: Risk increases when used with insulin or sulfonylureas.","Surgery: Discontinue temporarily before surgery and restart after 48 hours."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause hypoglycemia, lactic acidosis, or renal impairment. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for metformin overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider. Swallow the tablet whole with a glass of water. Take it with meals to reduce stomach upset. Stay well hydrated throughout the day to help prevent kidney problems. Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or imaging tests with contrast dyes. Check your blood sugar regularly as advised. Report any signs of infection, especially in the genital or urinary area, promptly. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially regarding kidney function. Regular monitoring of renal function is recommended. Dose adjustment may be needed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Discontinue this medicine temporarily before surgery and restart after 48 hours, as advised by your doctor. Monitor blood sugar closely during this period.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is beneficial for diabetes management, but monitor your blood sugar before and after exercise. Carry a source of fast-acting sugar in case of hypoglycemia. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not significantly impact your daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of kidney function, blood sugar, and vitamin B12 levels. Metformin can cause vitamin B12 deficiency over time. Dapagliflozin may increase the risk of genital infections. Regular follow-up with your doctor is essential to adjust the dose and monitor for complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are essential for managing type 2 diabetes and can complement medicine.
Evidence: Well-establishedOther classes like DPP-4 inhibitors, sulfonylureas, or insulin may be considered based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, maintain routine vaccinations as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about adjusting the timing of doses. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few days, but full effects on HbA1c may take 2-3 months.
A: It is not recommended if you have severe kidney impairment. Consult your doctor for dose adjustment.
A: Mild side effects often improve with time. If you experience severe or persistent symptoms, contact your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for glyfloz-m 5mg/500mg tablet er
View AllAlternative brands with exact same active ingredient:
-
dapatab m 5mg/500mg tabletOrris Pharmaceuticals ₹65.34 56.2% CHEAPER
-
dapasach m 5mg/500mg tabletCipla Ltd ₹70.00 53% CHEAPER
-
dapixa m 5mg/500mg tablet erTas Med India Pvt Ltd ₹70.31 52.8% CHEAPER
-
justoza-m 5/500 tablet erMankind Pharma Ltd ₹72.18 51.6% CHEAPER
-
dexiglu m 5 tablet erFusion Healthcare Pvt Ltd ₹72.19 51.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar levels but does not cure diabetes. Lifestyle changes and ongoing treatment are essential. - Myth: This medicine can be taken without food.
Fact: It should be taken with meals to reduce stomach upset and improve tolerability. - Myth: This medicine causes weight gain.
Fact: Dapagliflozin may cause modest weight loss, while metformin is weight-neutral or may cause slight weight loss.
🔄 Alternative Options
Generic Alternatives
- Dapagliflozin + Metformin generic tablets
Brand Alternatives
- Dapanova M 5mg/500mg Tablet